The Regulation of Microorganisms on Human Endocrine and Metabolic Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 25 February 2026 | Viewed by 428
Special Issue Editors
Interests: gut microbiome; microbial fermentation; microbiome-based therapy; metabolic disease
Special Issue Information
Dear Colleagues,
There has been a concerning global rise in the prevalence of metabolic diseases, including type 2 diabetes, metabolic dysfunction-associated fatty liver disease, and obesity. Recent multi-omics studies have highlighted the gut microbiome as an important factor in the modulation of the risk for cardiometabolic disease development. Furthermore, the gut microbiome has been shown to influence the efficacy of current treatments, such as glucose-lowering drugs. The role of microorganisms in regulating endocrine processes and responses to treatments is an emerging area of research, underscoring the complex relationship between the microbiome and human metabolic health, potentially through bacterial enzymes, cellular components, and metabolites.
Understanding how microorganisms influence endocrine and metabolic functions and responses to drugs is crucial for developing novel therapeutic approaches for cardiometabolic diseases. This Special Issue will explore the role of the gut microbiome in regulating the host responses using in vitro models, animal studies, human cohorts, and clinical interventions. We invite original research articles and review papers that contribute to a deeper understanding of the mechanisms modulated by the gut microbiota and their potential therapeutic implications.
Dr. Thi Phuong Nam Bui
Dr. Valentina Tremaroli
Guest Editors
Manuscript Submission Information
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Keywords
- human gut microbiome
- endocrine signaling
- metabolism
- obesity
- type 2 diabetes
- cardiometabolic diseases
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