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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular and Cellular Targets on Anticancer Research and Perspectives submission deadline 20 Aug 2026 | 1 articles | Viewed by 2374
Keywords: anticancer; molecular targets; targeted cancer therapies; malignancy
(This special issue belongs to the Section Molecular Oncology)
Advances in Stem Cell Biology and Translational Medicine
edited by Yangluowa Qu
submission deadline 20 Aug 2026 | 1 articles | Viewed by 2147
Keywords: stem cell regulation; differentiation; proliferation; self-renewal; stem cell-based therapy; tissue engineering; translational research
(This special issue belongs to the Section Molecular Biology)
Biomaterials and Antibacterial Materials for Medical Applications
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 2096
Keywords: biomaterial science; photodynamic antibacterial materials; photothermal antibacterial materials; advanced antibacterial materials; antimicrobial nanostructured materials; polymer-based biomaterials; infected wound dressings
(This special issue belongs to the Section Materials Science)
Kidney Disease: Molecular Insights and Emerging Therapies
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 2011
Keywords: kidney disease; molecular mechanism; precision medicine; translational nephrology; targeted molecular therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Insights into Mitochondrial Signaling and Homeostasis in Metabolic Diseases
edited by Ching-Yi Chen
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1988
Keywords: diabetes mellitus; cardiovascular disease; fatty liver; chronic kidney disease; mitochondrial homeostasis
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Advances and Views in Triple-Negative Breast Cancer
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1986
Keywords: breast cancer; molecular biology; personalized medicine; triple-negative breast cancer
(This special issue belongs to the Section Molecular Oncology)
Significance and Challenges of Plant-Derived Natural Compounds in Cancers
edited by Ba Vinh Le
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1977
Keywords: metabolomic; bioactive compound; pharmacognosy; oriental medicine; drug discovery; pharmacology; anti-cancer; pharmacological effects
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Fluorescent Sensors submission deadline 20 Aug 2026 | 1 articles | Viewed by 1966
Keywords: fluorescence probe; fluorescent nanomaterials; analyte recognition; fluorescence imaging; real-time monitoring; photoinduced electron transfer; Förster resonance energy transfer; genetically encoded indicators; sensor devices; fluorescence microscopy
(This special issue belongs to the Section Materials Science)
Evolutionary Drivers and Adaptive Mechanisms in Algal Organellar Genomes
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1912
Keywords: organellar genome of algae; molecular evolution; secondary structure of intron; evolutionary driving force; horizontal gene transfer
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Insights into Microglia in Neurological Diseases
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1904
Keywords: microglia; neuroinflammation; neurodegenerative diseases; molecular signaling; central nervous system (CNS)
(This special issue belongs to the Section Molecular Neurobiology)
Telocytes: Unraveling Their Roles in Health and Disease
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1845
Keywords: telocytes; telopodes; intercellular communication; stem cell niche; extracellular vesicles; regenerative medicine; tissue remodelling; stromal cells
(This special issue belongs to the Section Molecular Biology)
New Progress in Peptidic Protease Inhibitors
edited by and Carla Di Chio
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1792
Keywords: peptide inhibitors; infectious diseases; cancer; metabolic disorders; neurological disorders; inflammation
(This special issue belongs to the Section Biochemistry)
Natural Compounds in Neurological Diseases
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1790
Keywords: natural compounds; neuroprotection; neuroinflammation; oxidative stress; mitochondrial dysfunction; autophagy; bioactive molecules (polyphenols, flavonoids, melatonin, etc.); nutraceuticals (bioactive peptides, hydrolysates, etc.); neurodegenerative diseases
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms of Thromboinflammation
edited by Ana B. Arroyo
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1775
Keywords: thromboinflammation; coagulation; inflammation; immune system; sepsis; stroke; autoimmune diseases; cancer; hematology; biomarkers; translational medicine
(This special issue belongs to the Section Molecular Immunology)
Research on the Key Role of Ubiquitination in Signaling and Cancer
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1773
Keywords: ubiquitin; ubiquitination; E3 ligase; deubiquitinating enzymes; protein degradation; mutations; cancer progression; signal transduction; drug development
(This special issue belongs to the Section Molecular Oncology)
Molecular Research in Functional Nanomaterials
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1756
Keywords: functional materials; nanomaterials; molecular structure; molecular materials; functional molecules; nanotechnology; self-assembly methods
(This special issue belongs to the Section Molecular Nanoscience)
Research Progress of Fluorescent Proteins in Molecular Biology
edited by Matteo Grenzi
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1735
Keywords: fluorescence microscopy; fluorescence live-cell imaging; quantitative imaging; fluorescent biosensors; in vivo imaging; innovative fluorescence microscopy techniques
(This special issue belongs to the Section Molecular Biology)
New Insight into Bacteriophage and Their Potential Applications
edited by Wilfried Moreira
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1716
Keywords: bacteriophage; phage biology; phage-host interactions; antimicrobial resistance
(This special issue belongs to the Section Molecular Microbiology)
Recent Advances in Brain Tumor Research and Treatment submission deadline 20 Aug 2026 | 2 articles | Viewed by 1715
Keywords: brain tumor; gliomas; brain metastases; translational research; molecular biology
(This special issue belongs to the Section Molecular Oncology)
Molecular Research and Insights into Anti-Cancer Vaccines
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1683
Keywords: anti-cancer vaccines; tumor antigens; molecular mechanisms; immunotherapy; molecular oncology
(This special issue belongs to the Section Molecular Oncology)
Tumor Specific Immunotherapeutic Targets
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1660
Keywords: immunotherapy; immunotherapeutics; tumour-specific antigens; immunotherapeutic targets; multi-omics approaches
(This special issue belongs to the Section Molecular Immunology)
Molecular Research in Protein–Ligand Interactions
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1610
Keywords: interaction; protein–ligand; computer simulation; docking; molecular simulation
(This special issue belongs to the Section Biochemistry)
Recent Research on Natural Compounds in Cancer Treatment and Prevention submission deadline 20 Aug 2026 | 2 articles | Viewed by 1582
Keywords: natural compounds; bioactive phytochemicals; anticancer therapy; chemoprevention
(This special issue belongs to the Section Molecular Oncology)
AIEgens in Action: Design, Mechanisms, and Emerging Applications submission deadline 20 Aug 2026 | 1 articles | Viewed by 1560
Keywords: fluorescence effects; photophysical properties of small molecules; ion detection; molecular spectroscopy; various nanoparticle-based additives; fluorescent and phosphorescent phenomena in solvents, amorphous states, and crystals; quantum-mechanical calculations for molecular systems and compositions (DFT, TD-DFT); molecular aggregation influencing fluorescence and phosphorescence properties of tested systems
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
State-of-the-Art Electrochemical Reaction Technologies submission deadline 20 Aug 2026 | 1 articles | Viewed by 1531
Keywords: energy storage; electrochemical sensors; electrocatalysis; supercapacitors; molecular electrochemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Advances in Heart Disease: Genomics and Bioinformatics of Heart Research—2nd Edition
edited by Justyna Fert-Bober
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1472
Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Dendritic Cell-Based Immunotherapy of Cancer
edited by Helena Haque Chowdhury and Matjaz Jeras
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1466
Keywords: DC-based immunotherapy of cancer; immunostimulatory dendritic cell (DC) generation; dosage and routes of DC administration; body distribution of DCs post-application; frequency and duration of DC applications; tumour immunosuppressive mechanisms’ modulation; combinatorial DC-based anticancer immunotherapy
(This special issue belongs to the Section Molecular Immunology)
The Role of Diet in Lipid and Lipoprotein Metabolism
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1436
Keywords: dyslipidemia; hypertension; diabetes; dementia
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
New Optical, Electrical, and Thermal Materials: Recent Advances and Challenges
edited by Luyi Zou
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1433
Keywords: optical materials; electrical materials; thermal materials; molecular structure; molecular composition; structural performance
(This special issue belongs to the Section Materials Science)
Pregnancy-Related Complications: Molecular Pathogenesis and Therapeutic Strategies
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1388
Keywords: pregnancy-related complications; placental dysfunction; maternal-fetal communication; extracellular vesicles; translational research; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Early Diagnosis and Advanced Therapies of Genetic Disorders
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1382
Keywords: genetic disorders; rare diseases; disease diagnostics; therapeutic targets; gene variants
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Solid Tumors: From Molecular Mechanisms to Targeted Therapies
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1330
Keywords: solid tumors; cancer molecular mechanisms; oncogenic signaling pathways; epigenetic regulation; tumor microenvironment; molecular biomarkers; targeted therapies; precision oncology; drug resistance; translational cancer research
(This special issue belongs to the Section Molecular Oncology)
Protein-Targeted Therapeutics: Functional Modulation in Disease Pathways submission deadline 20 Aug 2026 | 1 articles | Viewed by 1316
Keywords: protein-targeted therapeutics; proteins inhibitors; ligand binding; conformational changes
(This special issue belongs to the Section Biochemistry)
Systems Approaches to Diabetic Complications
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1301
Keywords: diabetes; diabetic complications; molecular mechanisms; precision medicine
(This special issue belongs to the Section Molecular Biology)
Natural Products in Immune Regulation
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1280
Keywords: natural products; immune responses; immunomodulatory therapies
(This special issue belongs to the Section Molecular Immunology)
Chemical Tools for Microbial Functionalization: Bridging Organic Chemistry and Biotechnology
edited by Stefania Cicco and
submission deadline 20 Aug 2026 | Viewed by 1258
Keywords: organometallic biochemistry; green chemistry; bioorthogonal; living polymers; living functionalization; hybrid materials
(This special issue belongs to the Section Molecular Microbiology)
Endothelial Cells in Vascular Health and Immunity
edited by and Xianming Zhang
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1237
Keywords: endothelial cells; vascular health; cardiovascular disease; kidney disease; lung injury; inflammation; regenerative medicine; molecular therapy
(This special issue belongs to the Section Biochemistry)
Cognitive Aging: Molecular Perspectives
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1145
Keywords: brain; neuron; aging; neurodegeneration; cognitive neuroscience; inflammation; regeneration; behavioral neuroscience; pharmacology; brain disorders
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants
edited by Chi-Rei Wu and Li-Wei Lin
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1133
Keywords: plants; phenolic profiles; inflammation; cardiovascular disorders; cancer; diabetes; neurodegenerative disorders
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research in Renal Endocrinology submission deadline 20 Aug 2026 | 1 articles | Viewed by 1130
Keywords: renin–angiotensin system; natriuretic peptides; calcitriol; erythropoietin; prostaglandins; endothelins; adrenomedullin
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
MicroRNAs as Biomarkers in Chronic Diseases
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1066
Keywords: microRNA; biomarker; chronic diseases; cancer; cardiovascular diseases; psychiatric conditions
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Roots, Transporters, and Signals: Molecular Insights into Plant Mineral Nutrition and Heavy Metals Stress
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1018
Keywords: plant mineral nutrition; heavy metals; toxic element; transporter; signaling pathway
(This special issue belongs to the Section Molecular Plant Sciences)
Health-Promoting Benefits of Natural Products and Functional Foods, 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 1016
Keywords: natural products; functional foods; health promotion; nutrigenomics; evidence-based preventive healthcare; phytochemicals; biomarkers; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Recent Research in RNA–Protein Networks
edited by Hidenori Tani
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1006
Keywords: machine learning; bioinformatics; ribonucleoprotein; RNA–protein complex; alternative splicing; RNA stability; RNA localization
(This special issue belongs to the Section Molecular Biology)
Molecular Interactions at Biomaterial Interfaces submission deadline 20 Aug 2026 | 1 articles | Viewed by 985
Keywords: biocompatibility; biomaterial; surface-biomolecule interaction; surface science; material science
(This special issue belongs to the Section Molecular Biophysics)
Crucial Role of Intestinal Barriers and Their Impact on the Gut–Brain Axis in Health and Disease: Addressing Future Therapies submission deadline 20 Aug 2026 | 1 articles | Viewed by 965
Keywords: age; brain–gut microbiota axis; intestinal barrier; fetal; gender; sex
(This special issue belongs to the Section Molecular Biology)
New Therapies for CNS Diseases Targeting Biogenic Amines and Their Receptors submission deadline 20 Aug 2026 | 1 articles | Viewed by 958
Keywords: neurotransmitters; biogenic amines; receptors; ligands (antagonists, agonists, inverse agonists, biased ligands); neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease); neuroinflammation; CNS cancers; autoimmune disease (e.g., multiple sclerosis); neurological diseases; mental illness (schizophrenia, depression); epilepsy; pain; in vitro studies; in silico studies (ADMET, molecular modelling); in vivo studies
(This special issue belongs to the Section Molecular Neurobiology)
Plant Responses to Abiotic Stress: Mechanisms and Adaptations submission deadline 20 Aug 2026 | Viewed by 913
Keywords: salinity stress; heat and cold stress; oxidative stress; signal transduction; stress-responsive genes; antioxidant defence mechanisms; hormonal regulation; molecular adaptation; epigenetic regulation; plant-microbe interaction; crop improvement; stress-resilient plants
(This special issue belongs to the Section Molecular Plant Sciences)
Amino Acid and Sugar Metabolism in Disease
edited by V. Tkach
submission deadline 20 Aug 2026 | 1 articles | Viewed by 900
Keywords: metabolic diseases; metabolic disturbances; carbohydrate metabolism; aminoacid metabolism; artificial sweeteners; metabolic path alterations
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Carbon Fiber, Carbon Nanofiber for Composites: Synthesis, Processing, Molecular Structure, Characterization, and Application
edited by Tridung Ngo
submission deadline 20 Aug 2026 | Viewed by 894
Keywords: carbon fiber; carbon nanofiber; nanotube; carbon fiber composites; synthesis; advanced manufacturing; characterization; recent advancements; applications
(This special issue belongs to the Section Materials Science)
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