Recent Research in RNA-Protein Networks
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 5
Special Issue Editor
Interests: lncRNA function; RNA stability; RNA drug discovery; liquid–liquid phase separation (LLPS); stress response; RNA splicing; machine learning; RNA–protein interaction network
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
RNA-protein interactions represent one of the most fundamental and dynamic regulatory mechanisms in cellular biology, governing essential processes from gene expression to protein synthesis and cellular signaling. This Special Issue aims to showcase cutting-edge research and emerging methodologies in the rapidly evolving field of RNA–protein networks, providing insights into their complex regulatory roles and therapeutic potential.
We invite original research articles and comprehensive review manuscripts addressing the following key areas: (a) RNA–protein interaction prediction and computational approaches. Submissions exploring advanced computational methods, machine learning algorithms, and bioinformatics tools for predicting RNA–protein binding sites, interaction networks, and binding affinities are welcome. Articles discussing novel databases, web servers, and integrated platforms for RNA–protein interaction analysis are particularly welcome. (b) Functional RNA–protein complexes and ribonucleoprotein particles: research focusing on the structural and functional characterization of RNA–protein complexes, including ribosomes, spliceosomes, stress granules, and P-bodies. Studies investigating the assembly, dynamics, and regulatory mechanisms of these complexes are of high interest. (c) RNA-binding proteins and their regulatory networks: papers examining the roles of RNA-binding proteins in post-transcriptional regulation, alternative splicing, RNA stability, and localization. Investigations into disease-associated RNA-binding proteins and their therapeutic targeting are encouraged. (d) Emerging technologies and experimental approaches: submissions highlighting innovative experimental techniques such as CLIP-seq, RIP-seq, crosslinking mass spectrometry, and single-molecule imaging for studying RNA–protein interactions. Articles discussing the integration of multi-omics approaches and systems biology to understand RNA-protein networks are also welcome.
This Special Issue will provide a comprehensive platform for researchers, computational biologists, and clinicians working at the intersection of RNA biology and protein science, fostering collaboration and advancing our understanding of these critical cellular networks. This Special Issue will focus particularly on innovative methodologies for elucidating the roles of RNA–protein interactions in cellular processes, but other related topics will also be considered.
Dr. Hidenori Tani
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- machine learning
- bioinformatics
- ribonucleoprotein
- RNA-protein complex
- alternative splicing
- RNA stability
- RNA localization
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