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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Techniques to Study Food Safety Challenges submission deadline 20 Apr 2026 | Viewed by 151 | Submission Open
Keywords: food safety; hazards; foodborne pathogens; advanced microbial detection technologies; omics techniques; preventive measures
(This special issue belongs to the Section Molecular Microbiology)
Antimicrobial Agents and the Quest for Resistance Breakthroughs
edited by
submission deadline 20 Apr 2026 | Viewed by 149 | Submission Open
Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research on Andrology
edited by Elikanah Olusayo Adegoke
submission deadline 20 Apr 2026 | Viewed by 147 | Submission Open
Keywords: fertilty; assisted reproduction technology; endocrine disrupting chemicals; hormones; male reproductive aging; semen analysis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanomedicine: Application of Nanostructured Biomaterials in the Biomedical Field
edited by
submission deadline 20 Apr 2026 | Viewed by 144 | Submission Open
Keywords: nanomedicine; nanostructured biomaterials; targeted drug delivery; tissue regeneration; biosensing
(This special issue belongs to the Section Molecular Nanoscience)
New Advances in Reversing Cancer Therapy Resistance
edited by
submission deadline 20 Apr 2026 | Viewed by 142 | Submission Open
Keywords: cancer; natural compound; cell death; radioresistance; chemoresistance
(This special issue belongs to the Section Molecular Pharmacology)
Mitochondria-Associated Non-Coding RNAs
edited by , Jaime E. Villegas and
submission deadline 20 Apr 2026 | Viewed by 137 | Submission Open
Keywords: mitochondrial-encoded ncRNAs; mitochondrial miRNAs; mitochondrial lncRNAs; mitochondrial circRNAs; nuclear-encoded mitochondrial ncRNAs
(This special issue belongs to the Section Molecular Biology)
Novel Therapeutic Strategies and Targets in Rheumatoid Arthritis
edited by David Fox and
submission deadline 20 Apr 2026 | Viewed by 136 | Submission Open
Keywords: RA; synovium; FLS; synovial fluid; microbiome; autoimmunity; DMARD; joint inflammation; joint damage; nanoparticle
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 129 | Submission Open
Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging
(This special issue belongs to the Section Molecular Nanoscience)
Eco-Conscious Therapeutics: Molecular Foundations and Future Directions in Green Medicine
edited by and
submission deadline 20 Apr 2026 | Viewed by 128 | Submission Open
Keywords: green medicine; molecular therapeutics; sustainable healthcare; biomarker profiling; predictive toxicology; eco-friendly drug design; environmental impact; biodegradable materials
(This special issue belongs to the Section Molecular Toxicology)
Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection
edited by Enrico Gallo
submission deadline 20 Apr 2026 | Viewed by 128 | Submission Open
Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems
(This special issue belongs to the Section Materials Science)
Molecular Research in Leukemia
edited by Juan Manuel Mejia-Arangure
submission deadline 20 Apr 2026 | Viewed by 125 | Submission Open
Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nano-Biomaterials for Biomedicine and Tissue Regeneration
edited by and
submission deadline 20 Apr 2026 | Viewed by 121 | Submission Open
Keywords: nanostructured biomaterials; cell-scaffold interactions; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Antimicrobial Agents and Resistance Mechanisms submission deadline 20 Apr 2026 | Viewed by 120 | Submission Open
Keywords: acquired resistance; antibiotic inactivation; antibiotic modifications; antibiotic uptake; antibiotics; antimicrobial agents; bacterial dormancy; efflux pumps; extrachromosomal elements; genomic mutations; novel antimicrobial molecules; resistant mechanisms
(This special issue belongs to the Section Molecular Microbiology)
Genome Editing in Autologous Stem Cells: From Bench to Bedside
edited by
submission deadline 20 Apr 2026 | Viewed by 118 | Submission Open
Keywords: genome editing; gene therapy; autologous transplant; preclinical studies; process development; scalability; quality control; manufacturing; regulatory compliance; IND-enabling studies
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Advances in Antimicrobial Nanoparticles
edited by and
submission deadline 20 Apr 2026 | Viewed by 113 | Submission Open
Keywords: antimicrobial nanoparticles; resistant pathogens; antimicrobial resistance; lipid nanoparticles; biomimetic nanostructures; combined therapy; antimicrobial strategies
(This special issue belongs to the Section Molecular Nanoscience)
Nanocomposite Fibers: Current Status and Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 111 | Submission Open
Keywords: advanced fibrous and particulate materials; nano-enhanced textiles; natural fiber utilization; fiber quality; textile processing
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition
edited by
submission deadline 20 Apr 2026 | Viewed by 111 | Submission Open
Keywords: metastasis; fibrosis; tumor microenvironment; molecular pathways; EMT reversion
(This special issue belongs to the Section Molecular Biology)
Metal Toxicity and Particle Toxicity
edited by Alicja Piotrowska-Niczyporuk
submission deadline 20 Apr 2026 | Viewed by 106 | Submission Open
Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae
(This special issue belongs to the Section Molecular Toxicology)
Dynamic Nanoarchitectonics in Supramolecular Assemblies and Nanosystems: From Synthesis to Applications submission deadline 20 Apr 2026 | Viewed by 103 | Submission Open
Keywords: supramolecular chemistry; synthetic chemistry; nanoscale materials; nanostructured materials; molecular self-assembly; nanoparticles; nanotechnology
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Molecular Genetics of Head and Neck Cancer
edited by
submission deadline 20 Apr 2026 | Viewed by 102 | Submission Open
Keywords: head and neck cancer; molecular genetics; tumor heterogeneity; driver mutations; epigenetic alterations; non-coding RNAs; oncogenes and tumor suppressors; gene expression profiling; genomic instability; biomarkers for diagnosis and therapy
(This special issue belongs to the Section Molecular Oncology)
Biomaterials for Dental and Orthopedic Applications, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 68 | Submission Open
Keywords: personalized biomaterials; dental and orthopedic applications; tissue regeneration; 3D biorinting
(This special issue belongs to the Section Materials Science)
Tumor Markers and Tumor Microenvironment
edited by Tamás Micsik
submission deadline 20 Apr 2026 | Viewed by 66 | Submission Open
Keywords: tumor markers; tumor environment; molecular and genetics; omics; artificial intelligence; digital pathology; computational pathology; individualized therapy; prognostication
(This special issue belongs to the Section Molecular Oncology)
Latest Research on Drug-Diagnostics Co-Development in Oncology submission deadline 20 Apr 2026 | Viewed by 57 | Submission Open
Keywords: companion diagnostics; tumor; drug– diagnostic co-development; molecular profiling; biomarker; theranostics
(This special issue belongs to the Section Molecular Oncology)
Plant Responses to Abiotic and Biotic Stresses: 2nd Editon
edited by and
submission deadline 20 Apr 2026 | Viewed by 57 | Submission Open
Keywords: climate change and crop production; abiotic stress; biotic stress; plant resistance to abiotic and biotic stresses; molecular mechanism; physiological responses; plant hormones; carbohydrate metabolism and transport; molecular signaling; reactive oxygen species (ROS); calcium ions; photosynthesis; respiration; energy metabolism
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Advances in Obstetrical and Gynaecological Disorders: 2nd Edition submission deadline 20 Apr 2026 | Viewed by 44 | Submission Open
Keywords: gynaecological disorders; obstetrical disorders; gynaecological diseases; genetic markers; molecular therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Research on Natural Compounds: Biosynthesis, Analysis, and Application submission deadline 20 Apr 2026 | Viewed by 39 | Submission Open
Keywords: phytochemicals; natural compounds; chromatography; MS; NMR; analysis; identification; extraction; standardisation; quantitation; activity; moleabular mechanism; biosynthesis
(This special issue belongs to the Section Biochemistry)
From Molecular Mechanisms to Precision Medicine in Gastrointestinal Cancers: (Epi)genetics, Pharmacogenomics, and Emerging Biomarkers submission deadline 20 Apr 2026 | Viewed by 37 | Submission Open
Keywords: gastrointestinal and colorectal cancer; genetic and epigenetic regulation; multi-omics and computational biology; molecular pathology and biomarker discovery; translational and precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Epigenetic and Post-Transcriptional Regulation of Gene Expression
edited by Lidia Borkiewicz
submission deadline 20 Apr 2026 | Viewed by 32 | Submission Open
Keywords: epigenome; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; epitranscriptome; alternative splicing; RNA methylation; RNA edition
(This special issue belongs to the Section Molecular Biology)
Advances in Metalloproteinase, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 16 | Submission Open
Keywords: matrix metalloproteinases (MMPs); substrate specificity; pathological condition; metalloproteinases inhibitors
(This special issue belongs to the Section Biochemistry)
Triosephosphate Isomerase: Potential Target in Cancer Treatment and Other Diseases submission deadline 24 Apr 2026 | 1 articles | Viewed by 1245 | Submission Open
Keywords: cancer; glycolytic; triosephosphate isomerase; TPI; post-translational modification; cancer treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Food Allergens: Latest Molecular Advancements
edited by and
submission deadline 24 Apr 2026 | Viewed by 156 | Submission Open
Keywords: food allergies; allergen; allergenicity; epitope; desensitization; immunity reaction; hypoallergen; Ig E binding             TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in German   Translate to Simplified Chinese         Abkhazian Acehnese Acholi Afar Afrikaans Albanian Alur Amharic Arabic Armenian Assamese Avaric Awadhi Aymara Azerbaijani Balinese Baluchi Bambara Baoulé Bashkir Basque Batak Batak Simalungun Batak Toba Belarusian Bemba Bengali Betawi Bhojpuri Bikol Bosnian Breton Bulgarian Buryat Cantonese Catalan Cebuano Chamorro Chechen Chichewa Chuukese Chuvash Corsican Crimean Tatar Crimean Tatar (Latin) Croatian Czech Danish Dari Dinka Divehi Dogri Dombe Dutch Dyula Dzongkha English English (USA) Esperanto Estonian Ewe Faroese Fijian Filipino Finnish Fon French French (Canadian) Frisian Friulian Fulah Ga Galician Georgian German Greek Guarani Gujarati Haitian Creole Hakha Falam Hausa Hawaiian Hebrew Hiligaynon Hindi Hmong Hungarian Hunsrik Iban Icelandic Igbo Ilocano Indonesian Inuktitut Inuktitut (Latin) Irish Italian Jamaican Patois Japanese Javanese Jingpho Kalaallisut Kannada Kanuri Kapampangan Kazakh Khasi Khmer Kiga Kikongo Kinyarwanda Kokborok Komi Konkani (Latin) Korean Krio Kurdish (Kurmanji) Kurdish (Sorani) Kyrgyz Lao Latgalian Latin Latvian Ligurian Limburgish Lingala Lithuanian Lombard Luganda Luo Luxembourgish Macedonian Madurese Maithili Makassarese Malagasy Malay Malay (Arabic) Malayalam Maltese Mam Manx Maori Marathi Mari Marshallese Marwari Mauritian Creole Meitei/Meetei (Mayek) Minangkabau Mizo Mongolian Myanmar (Burmese) N'Ko Bambara Nahuatl Ndau (Zimbabwe) Ndebele Nepali Newari Northern Sami Norwegian Nuer Occitan Odia Oromo Ossetian Pangasinan Papiamento Pashto Persian Polish Portuguese Portuguese (Portugal) Punjabi Punjabi (Arabic) Q'eqchi' Quechua Romani Romanian Rundi Russian Samoan Sango Sanskrit Santali Santali (Latin) Scots Gaelic Sepedi Serbian Sesotho Seychellois Creole Shan Shona Sicilian Silesian Simplified Chinese Sindhi Sinhala Slovak Slovenian Somali Spanish Sundanese Susu Swahili Swati Swedish Tahitian Tajik Tamazight Tamazight (Latin) Tamil Tatar Telugu Tetum Thai Tibetan Tigrinya Tiv Tok Pisin Tongan Traditional Chinese Tshiluba Tsonga Tswana Tulu Tumbuka Turkish Turkmen Tuvan Twi Udmurt Ukrainian Urdu Uyghur Uzbek Venda Venetian Vietnamese Waray Welsh Wolof Xhosa Yakut Yiddish Yoruba Yucatec Maya Zapotec Zulu   Always translate German to Simplified Chinese Never translate German Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Biology)
Identification of Predictive Molecular Markers for Cancer Progression, Response to Therapy, and Disease Outcome
edited by
submission deadline 25 Apr 2026 | Viewed by 195 | Submission Open
Keywords: predictive biomarkers; cancer progression; therapy response; molecular signatures; precision oncology
(This special issue belongs to the Section Molecular Oncology)
Innovations in Functional Biomaterials for Biomedical Applications
edited by
submission deadline 25 Apr 2026 | Viewed by 109 | Submission Open
Keywords: functional biomaterials; molecular mechanisms; drug delivery systems; tissue engineering; biointerface interactions; smart/stimuli-responsive materials; molecular modeling and simulation; gene and protein expression; biomolecular characterization; regenerative medicine
(This special issue belongs to the Section Materials Science)
Nanomaterials and Regulated Cell Death Pathways: Novel Therapeutic Opportunities
edited by
submission deadline 25 Apr 2026 | Viewed by 89 | Submission Open
Keywords: apoptosis; ferroptosis; nanotherapy; nanotoxicity; necroptosis; oxidative stress; PANoptosis; pyroptosis; regulated cell death
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Cardiovascular Disease and Medicine
edited by Kristoffer Berg-Hansen
submission deadline 25 Apr 2026 | Viewed by 68 | Submission Open
Keywords: cardiovascular disease; molecular mechanisms; genetics; epigenetics; omics; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Ophthalmic Diseases
edited by
submission deadline 27 Apr 2026 | Viewed by 182 | Submission Open
Keywords: environmental hazards; ophthalmic diseases; molecular mechanisms; risk factors; disease prevention; oxidative stress; biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advance in Nutraceutical Research: From Bioactive Discovery to Translational Application submission deadline 27 Apr 2026 | Viewed by 94 | Submission Open
Keywords: bioactive compounds; nutraceuticals; molecular mechanisms; nutraceutical formulations; preclinical and clinical validation; targeted delivery systems
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Next-Generation Sequencing for Aging and Cancer Research
edited by Hyunsoo Kim
submission deadline 28 Apr 2026 | Viewed by 6 | Submission Open
Keywords: next-generation sequencing; aging; cancer genomics; cellular senescence; single-cell sequencing; epigenomics; transcriptomics; tumor evolution; biomarkers; precision medicine
(This special issue belongs to the Section Molecular Informatics)
Molecular Insights into Toxicity: Identifying Biomarkers and Molecular Pathways Involved in Toxicological Responses
edited by Irma Martha Medina Díaz
submission deadline 29 Apr 2026 | 1 articles | Viewed by 2133 | Submission Open
Keywords: biomarkers; molecular pathways; chemical exposure assessment; environmental exposure; human health; public health toxicology
(This special issue belongs to the Section Molecular Toxicology)
Harnessing Natural Compounds to Combat Cancer and Metastasis
edited by
submission deadline 29 Apr 2026 | Viewed by 294 | Submission Open
Keywords: natural compounds; bioactive molecules; natural extracts; chemotherapy; immunomodulatory compounds; anti-metastatic compounds; anti-angiogenic compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms of Cardiac Development and Disease (Second Edition) submission deadline 29 Apr 2026 | Viewed by 146 | Submission Open
Keywords: cardiac development; cardiac repair; regeneration; cardiac cell-cell interaction; fibrosis; remodeling; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Systemic and Mucosal Inflammation in Colorectal Cancer: Underlying Factors, Significance, and Related Biomarkers, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1903 | Submission Open
Keywords: molecular changes; colorectal cancer; normal mucosa; apoptotic proteins; inflammatory mechanism; adenoma– carcinoma sequence; cancer biomarkers
(This special issue belongs to the Section Molecular Oncology)
Advances in Molecular Approaches to Asthma Management submission deadline 30 Apr 2026 | 1 articles | Viewed by 1291 | Submission Open
Keywords: severe asthma; type 2 and non-type 2 inflammation; antibodies; comorbidities; treatable traits
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Maternal Effects on Infant Neurodevelopment submission deadline 30 Apr 2026 | 1 articles | Viewed by 437 | Submission Open
Keywords: maternal– fetal interactions; epigenetic regulation; neurodevelopmental programming; placental signaling; glucocorticoid receptors; brain-derived neurotrophic factor (BDNF); oxidative stress; synaptic plasticity; perinatal stress; corticotropin-releasing factor (CRF) pathway
(This special issue belongs to the Section Molecular Neurobiology)
Deciphering the Molecular Symphony of Microbiome-Driven Immune Modulation
edited by Edda Russo and
submission deadline 30 Apr 2026 | Viewed by 396 | Submission Open
Keywords: microbiome; immune; microbial-host interactions
(This special issue belongs to the Section Molecular Immunology)
Computer Simulation Insight into Ligand–Receptor Interaction submission deadline 30 Apr 2026 | Viewed by 247 | Submission Open
Keywords: structure– activity relationship (SAR); free energy perturbation (FEP); structure-based drug design (SBDD); machine learning in drug discovery; hybrid qm/mm methods; binding affinity prediction; enhanced sampling techniques; target binding kinetics
(This special issue belongs to the Section Molecular Informatics)
Human Meningioma: Recent Developments
edited by Jason P. Sheehan, Yuki Shinya and Stylianos Pikis
submission deadline 30 Apr 2026 | Viewed by 202 | Submission Open
Keywords: meningioma; molecular pathogenesis; genomic alteration; radiogenomics; tumor microenvironment; biomarkers; neurosurgery; radiosurgery; translational neuroscience; artificial intelligence
(This special issue belongs to the Section Molecular Oncology)
Design, Synthesis, and Applications of Advanced Functional Materials
edited by
submission deadline 30 Apr 2026 | Viewed by 199 | Submission Open
Keywords: advanced functional materials; materials synthesis; nanomaterials; hybrid materials
(This special issue belongs to the Section Materials Science)
Exploring Molecular Progression in Inorganic Synthesis
edited by
submission deadline 30 Apr 2026 | Viewed by 179 | Submission Open
Keywords: inorganic synthesis; materials science; catalysis; energy materials; bioinorganic systems; organometallic compounds; supramolecular chemistry; molecular design
(This special issue belongs to the Section Materials Science)
Transition-Metal-Based Nanoparticles: Synthesis, Properties and Applications
edited by Ramin Yousefi and
submission deadline 30 Apr 2026 | Viewed by 164 | Submission Open
Keywords: transition metal nanoparticles; synthesis; structure– property relationship; catalysis; photocatalysis; energy storage and conversion; biomedical applications; drug delivery; environmental remediation; plasmonics
(This special issue belongs to the Section Molecular Nanoscience)
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