Molecular Insights into Toxicity: Identifying Biomarkers and Molecular Pathways Involved in Toxicological Responses
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: closed (29 April 2026) | Viewed by 3245
Special Issue Editor
Interests: biomarkers; molecular biology; toxicology; gene expression; environmental exposure
Special Issue Information
Dear Colleagues,
Recent advances in molecular biology, chemistry, and omics technologies have significantly enhanced our understanding of the mechanisms driving toxicity and disease development. Biomarkers have become essential tools for the early detection of adverse effects, monitoring of disease progression, and assessment of environmental and occupational exposures. These molecular indicators serve as crucial links between chemical exposure and health outcomes in both humans and wildlife, playing a central role in toxicology and molecular medicine. In light of increasing concerns regarding the effects of pollutants—such as pesticides, heavy metals, and emerging contaminants—on public and environmental health, there is an urgent need to identify novel biomarkers and to elucidate the molecular pathways involved in toxicological responses.
This Special Issue is supervised by Prof. Dr. Irma Martha Medina Díaz and assisted by Dr. José Francisco Herrera Moreno and Dr. Gabriela María Ávila Villareal (Universidad Autónoma de Nayarit). It aims to provide a platform for high-quality original research, reviews, short communications, perspectives, and other contributions focused on the discovery, validation, and application of biomarkers in toxicological settings. We particularly welcome interdisciplinary studies that integrate molecular biology, chemistry, toxicology, and systems biology to address health risks associated with chemical and environmental exposures. Topics of interest include, but are not limited to, mechanistic toxicology, biomarker development for human and ecological health, exposure assessment, oxidative stress, inflammation, epigenetic and transcriptomic responses, as well as advances in in vitro and in vivo models. By bridging the fields of human and environmental health, this Special Issue seeks to promote scientific dialogue that supports evidence-based risk assessment and informs public health and regulatory policy.
Prof. Dr. Irma Martha Medina Díaz
Guest Editor
Dr. José Francisco Herrera Moreno
Dr. Gabriela María Ávila Villareal
Guest Editor Assistants
Manuscript Submission Information
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Keywords
- biomarkers
- molecular pathways
- chemical exposure assessment
- environmental exposure
- human health
- public health toxicology
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