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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection
edited by Enrico Gallo
submission deadline 20 Apr 2026 | Viewed by 138 | Submission Open
Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems
(This special issue belongs to the Section Materials Science)
Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition
edited by
submission deadline 20 Apr 2026 | Viewed by 137 | Submission Open
Keywords: metastasis; fibrosis; tumor microenvironment; molecular pathways; EMT reversion
(This special issue belongs to the Section Molecular Biology)
Epigenetic and Post-Transcriptional Regulation of Gene Expression
edited by
submission deadline 20 Apr 2026 | Viewed by 135 | Submission Open
Keywords: epigenome; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; epitranscriptome; alternative splicing; RNA methylation; RNA edition
(This special issue belongs to the Section Molecular Biology)
Nano-Biomaterials for Biomedicine and Tissue Regeneration
edited by and
submission deadline 20 Apr 2026 | Viewed by 135 | Submission Open
Keywords: nanostructured biomaterials; cell-scaffold interactions; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Molecular Nanoscience)
Genome Editing in Autologous Stem Cells: From Bench to Bedside
edited by
submission deadline 20 Apr 2026 | Viewed by 128 | Submission Open
Keywords: genome editing; gene therapy; autologous transplant; preclinical studies; process development; scalability; quality control; manufacturing; regulatory compliance; IND-enabling studies
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Advances in Antimicrobial Nanoparticles
edited by and
submission deadline 20 Apr 2026 | Viewed by 126 | Submission Open
Keywords: antimicrobial nanoparticles; resistant pathogens; antimicrobial resistance; lipid nanoparticles; biomimetic nanostructures; combined therapy; antimicrobial strategies
(This special issue belongs to the Section Molecular Nanoscience)
Nanocomposite Fibers: Current Status and Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 122 | Submission Open
Keywords: advanced fibrous and particulate materials; nano-enhanced textiles; natural fiber utilization; fiber quality; textile processing
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Molecular Genetics of Head and Neck Cancer submission deadline 20 Apr 2026 | Viewed by 119 | Submission Open
Keywords: head and neck cancer; molecular genetics; tumor heterogeneity; driver mutations; epigenetic alterations; non-coding RNAs; oncogenes and tumor suppressors; gene expression profiling; genomic instability; biomarkers for diagnosis and therapy
(This special issue belongs to the Section Molecular Oncology)
Metal Toxicity and Particle Toxicity
edited by Alicja Piotrowska-Niczyporuk
submission deadline 20 Apr 2026 | Viewed by 118 | Submission Open
Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae
(This special issue belongs to the Section Molecular Toxicology)
Dynamic Nanoarchitectonics in Supramolecular Assemblies and Nanosystems: From Synthesis to Applications submission deadline 20 Apr 2026 | Viewed by 116 | Submission Open
Keywords: supramolecular chemistry; synthetic chemistry; nanoscale materials; nanostructured materials; molecular self-assembly; nanoparticles; nanotechnology
(This special issue belongs to the Section Molecular Nanoscience)
Plant Responses to Abiotic and Biotic Stresses: 2nd Editon
edited by and
submission deadline 20 Apr 2026 | Viewed by 90 | Submission Open
Keywords: climate change and crop production; abiotic stress; biotic stress; plant resistance to abiotic and biotic stresses; molecular mechanism; physiological responses; plant hormones; carbohydrate metabolism and transport; molecular signaling; reactive oxygen species (ROS); calcium ions; photosynthesis; respiration; energy metabolism
(This special issue belongs to the Section Molecular Plant Sciences)
From Molecular Mechanisms to Precision Medicine in Gastrointestinal Cancers: (Epi)genetics, Pharmacogenomics, and Emerging Biomarkers submission deadline 20 Apr 2026 | Viewed by 89 | Submission Open
Keywords: gastrointestinal and colorectal cancer; genetic and epigenetic regulation; multi-omics and computational biology; molecular pathology and biomarker discovery; translational and precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biomaterials for Dental and Orthopedic Applications, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 87 | Submission Open
Keywords: personalized biomaterials; dental and orthopedic applications; tissue regeneration; 3D biorinting
(This special issue belongs to the Section Materials Science)
Tumor Markers and Tumor Microenvironment
edited by Tamás Micsik
submission deadline 20 Apr 2026 | Viewed by 85 | Submission Open
Keywords: tumor markers; tumor environment; molecular and genetics; omics; artificial intelligence; digital pathology; computational pathology; individualized therapy; prognostication
(This special issue belongs to the Section Molecular Oncology)
Molecular Advances in Obstetrical and Gynaecological Disorders: 2nd Edition submission deadline 20 Apr 2026 | Viewed by 85 | Submission Open
Keywords: gynaecological disorders; obstetrical disorders; gynaecological diseases; genetic markers; molecular therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Latest Research on Drug-Diagnostics Co-Development in Oncology submission deadline 20 Apr 2026 | Viewed by 82 | Submission Open
Keywords: companion diagnostics; tumor; drug– diagnostic co-development; molecular profiling; biomarker; theranostics
(This special issue belongs to the Section Molecular Oncology)
Recent Research on Natural Compounds: Biosynthesis, Analysis, and Application submission deadline 20 Apr 2026 | Viewed by 79 | Submission Open
Keywords: phytochemicals; natural compounds; chromatography; MS; NMR; analysis; identification; extraction; standardisation; quantitation; activity; moleabular mechanism; biosynthesis
(This special issue belongs to the Section Biochemistry)
Advances in Metalloproteinase, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 36 | Submission Open
Keywords: matrix metalloproteinases (MMPs); substrate specificity; pathological condition; metalloproteinases inhibitors
(This special issue belongs to the Section Biochemistry)
Biomolecular Stratification in Antiphospholipid Syndrome
edited by
submission deadline 20 Apr 2026 | Viewed by 33 | Submission Open
Keywords: antiphospholipid syndrome; antiphospholipid; stratification; biomolecular; risk stratification; classification
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Triosephosphate Isomerase: Potential Target in Cancer Treatment and Other Diseases submission deadline 24 Apr 2026 | 1 articles | Viewed by 1494 | Submission Open
Keywords: cancer; glycolytic; triosephosphate isomerase; TPI; post-translational modification; cancer treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Food Allergens: Latest Molecular Advancements
edited by and
submission deadline 24 Apr 2026 | 1 articles | Viewed by 437 | Submission Open
Keywords: food allergies; allergen; allergenicity; epitope; desensitization; immunity reaction; hypoallergen; Ig E binding             TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in German   Translate to Simplified Chinese         Abkhazian Acehnese Acholi Afar Afrikaans Albanian Alur Amharic Arabic Armenian Assamese Avaric Awadhi Aymara Azerbaijani Balinese Baluchi Bambara Baoulé Bashkir Basque Batak Batak Simalungun Batak Toba Belarusian Bemba Bengali Betawi Bhojpuri Bikol Bosnian Breton Bulgarian Buryat Cantonese Catalan Cebuano Chamorro Chechen Chichewa Chuukese Chuvash Corsican Crimean Tatar Crimean Tatar (Latin) Croatian Czech Danish Dari Dinka Divehi Dogri Dombe Dutch Dyula Dzongkha English English (USA) Esperanto Estonian Ewe Faroese Fijian Filipino Finnish Fon French French (Canadian) Frisian Friulian Fulah Ga Galician Georgian German Greek Guarani Gujarati Haitian Creole Hakha Falam Hausa Hawaiian Hebrew Hiligaynon Hindi Hmong Hungarian Hunsrik Iban Icelandic Igbo Ilocano Indonesian Inuktitut Inuktitut (Latin) Irish Italian Jamaican Patois Japanese Javanese Jingpho Kalaallisut Kannada Kanuri Kapampangan Kazakh Khasi Khmer Kiga Kikongo Kinyarwanda Kokborok Komi Konkani (Latin) Korean Krio Kurdish (Kurmanji) Kurdish (Sorani) Kyrgyz Lao Latgalian Latin Latvian Ligurian Limburgish Lingala Lithuanian Lombard Luganda Luo Luxembourgish Macedonian Madurese Maithili Makassarese Malagasy Malay Malay (Arabic) Malayalam Maltese Mam Manx Maori Marathi Mari Marshallese Marwari Mauritian Creole Meitei/Meetei (Mayek) Minangkabau Mizo Mongolian Myanmar (Burmese) N'Ko Bambara Nahuatl Ndau (Zimbabwe) Ndebele Nepali Newari Northern Sami Norwegian Nuer Occitan Odia Oromo Ossetian Pangasinan Papiamento Pashto Persian Polish Portuguese Portuguese (Portugal) Punjabi Punjabi (Arabic) Q'eqchi' Quechua Romani Romanian Rundi Russian Samoan Sango Sanskrit Santali Santali (Latin) Scots Gaelic Sepedi Serbian Sesotho Seychellois Creole Shan Shona Sicilian Silesian Simplified Chinese Sindhi Sinhala Slovak Slovenian Somali Spanish Sundanese Susu Swahili Swati Swedish Tahitian Tajik Tamazight Tamazight (Latin) Tamil Tatar Telugu Tetum Thai Tibetan Tigrinya Tiv Tok Pisin Tongan Traditional Chinese Tshiluba Tsonga Tswana Tulu Tumbuka Turkish Turkmen Tuvan Twi Udmurt Ukrainian Urdu Uyghur Uzbek Venda Venetian Vietnamese Waray Welsh Wolof Xhosa Yakut Yiddish Yoruba Yucatec Maya Zapotec Zulu   Always translate German to Simplified Chinese Never translate German Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Biology)
Identification of Predictive Molecular Markers for Cancer Progression, Response to Therapy, and Disease Outcome
edited by
submission deadline 25 Apr 2026 | Viewed by 257 | Submission Open
Keywords: predictive biomarkers; cancer progression; therapy response; molecular signatures; precision oncology
(This special issue belongs to the Section Molecular Oncology)
Innovations in Functional Biomaterials for Biomedical Applications
edited by
submission deadline 25 Apr 2026 | Viewed by 117 | Submission Open
Keywords: functional biomaterials; molecular mechanisms; drug delivery systems; tissue engineering; biointerface interactions; smart/stimuli-responsive materials; molecular modeling and simulation; gene and protein expression; biomolecular characterization; regenerative medicine
(This special issue belongs to the Section Materials Science)
Nanomaterials and Regulated Cell Death Pathways: Novel Therapeutic Opportunities
edited by
submission deadline 25 Apr 2026 | Viewed by 105 | Submission Open
Keywords: apoptosis; ferroptosis; nanotherapy; nanotoxicity; necroptosis; oxidative stress; PANoptosis; pyroptosis; regulated cell death
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Cardiovascular Disease and Medicine
edited by Kristoffer Berg-Hansen
submission deadline 25 Apr 2026 | Viewed by 92 | Submission Open
Keywords: cardiovascular disease; molecular mechanisms; genetics; epigenetics; omics; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Ophthalmic Diseases
edited by
submission deadline 27 Apr 2026 | Viewed by 213 | Submission Open
Keywords: environmental hazards; ophthalmic diseases; molecular mechanisms; risk factors; disease prevention; oxidative stress; biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advance in Nutraceutical Research: From Bioactive Discovery to Translational Application submission deadline 27 Apr 2026 | Viewed by 110 | Submission Open
Keywords: bioactive compounds; nutraceuticals; molecular mechanisms; nutraceutical formulations; preclinical and clinical validation; targeted delivery systems
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Next-Generation Sequencing for Aging and Cancer Research
edited by Hyunsoo Kim
submission deadline 28 Apr 2026 | Viewed by 36 | Submission Open
Keywords: next-generation sequencing; aging; cancer genomics; cellular senescence; single-cell sequencing; epigenomics; transcriptomics; tumor evolution; biomarkers; precision medicine
(This special issue belongs to the Section Molecular Informatics)
Molecular Insights into Toxicity: Identifying Biomarkers and Molecular Pathways Involved in Toxicological Responses
edited by Irma Martha Medina Díaz
submission deadline 29 Apr 2026 | 1 articles | Viewed by 2331 | Submission Open
Keywords: biomarkers; molecular pathways; chemical exposure assessment; environmental exposure; human health; public health toxicology
(This special issue belongs to the Section Molecular Toxicology)
Harnessing Natural Compounds to Combat Cancer and Metastasis
edited by
submission deadline 29 Apr 2026 | Viewed by 332 | Submission Open
Keywords: natural compounds; bioactive molecules; natural extracts; chemotherapy; immunomodulatory compounds; anti-metastatic compounds; anti-angiogenic compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms of Cardiac Development and Disease (Second Edition) submission deadline 29 Apr 2026 | Viewed by 179 | Submission Open
Keywords: cardiac development; cardiac repair; regeneration; cardiac cell-cell interaction; fibrosis; remodeling; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism Discovery of the Bioactive Phytochemicals Against Different Diseases Based on Network Pharmacology and Molecular Docking, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 6 articles | Viewed by 13875 | Submission Open
Keywords: molecular mechanism; phytochemicals; network pharmacology; molecular docking; diseases; curing targets; signaling pathway; biological processes
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Insights into the Developmental Origins of Health and Disease, 2nd Edition submission deadline 30 Apr 2026 | 2 articles | Viewed by 2660 | Submission Open
Keywords: Developmental Origins of Health and Disease (DOHaD); fetal development; maternal nutrition; molecular programming; epigenetic modifications; environmental exposures; genetic factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Systemic and Mucosal Inflammation in Colorectal Cancer: Underlying Factors, Significance, and Related Biomarkers, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2054 | Submission Open
Keywords: molecular changes; colorectal cancer; normal mucosa; apoptotic proteins; inflammatory mechanism; adenoma– carcinoma sequence; cancer biomarkers
(This special issue belongs to the Section Molecular Oncology)
Advances in Molecular Approaches to Asthma Management submission deadline 30 Apr 2026 | 1 articles | Viewed by 1507 | Submission Open
Keywords: severe asthma; type 2 and non-type 2 inflammation; antibodies; comorbidities; treatable traits
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Therapeutic Targets in Cancers: 4th Edition
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 932 | Submission Open
Keywords: targeted therapy; precision oncology; immune modulation; cancer stem cell targeting; RNA-based therapy
(This special issue belongs to the Section Molecular Oncology)
Computer Simulation Insight into Ligand–Receptor Interaction submission deadline 30 Apr 2026 | 1 articles | Viewed by 655 | Submission Open
Keywords: structure– activity relationship (SAR); free energy perturbation (FEP); structure-based drug design (SBDD); machine learning in drug discovery; hybrid qm/mm methods; binding affinity prediction; enhanced sampling techniques; target binding kinetics
(This special issue belongs to the Section Molecular Informatics)
Molecular Mechanisms of Maternal Effects on Infant Neurodevelopment submission deadline 30 Apr 2026 | 1 articles | Viewed by 639 | Submission Open
Keywords: maternal– fetal interactions; epigenetic regulation; neurodevelopmental programming; placental signaling; glucocorticoid receptors; brain-derived neurotrophic factor (BDNF); oxidative stress; synaptic plasticity; perinatal stress; corticotropin-releasing factor (CRF) pathway
(This special issue belongs to the Section Molecular Neurobiology)
The Latest Research on Molecular Studies of Crustaceans
edited by and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 483 | Submission Open
Keywords: crustacean; molecular; genetics; physiology; ecology; environmental
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Heredity and Metabolism of Osteosarcoma submission deadline 30 Apr 2026 | 1 articles | Viewed by 481 | Submission Open
Keywords: osteosarcoma; clinical imaging; genetics; epigenetics; metabolism; signal transduction; stemness; pathology; metastasis; novel druggable target
(This special issue belongs to the Section Molecular Oncology)
New Insights in Antibiotic Resistance/Tolerance
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 472 | Submission Open
Keywords: antibiotic resistance; biofilm; innovative antimicrobial strategies and compounds; synergistic actions; One Health; bacterial tolerant phenotypes; resistant pathogenic microorganisms; mechanisms of antimicrobial resistance
(This special issue belongs to the Section Molecular Microbiology)
Green Synthesis of Biomaterials Using Plant Extracts with Potential Application in Medicine and Biotechnology submission deadline 30 Apr 2026 | 1 articles | Viewed by 438 | Submission Open
Keywords: green synthesis; biomaterials; antimicrobial activity; plant-mediated green synthesis; biomedical application; antibiotic resistance
(This special issue belongs to the Section Materials Science)
Deciphering the Molecular Symphony of Microbiome-Driven Immune Modulation
edited by Edda Russo and
submission deadline 30 Apr 2026 | Viewed by 420 | Submission Open
Keywords: microbiome; immune; microbial-host interactions
(This special issue belongs to the Section Molecular Immunology)
Intermittent Hypoxia: Physiological and Biomedical Perspectives
edited by , and Norma Alva
submission deadline 30 Apr 2026 | 1 articles | Viewed by 368 | Submission Open
Keywords: altitude training; cardiovascular adaptation; endothelial dysfunction; EPO; intermittent hypoxia conditioning programs; HIF-1; neuroplasticity; obstructive sleep apnea; oxidative stress; pulmonary hypertension
(This special issue belongs to the Section Molecular Biology)
Next-Generation Antimicrobials and Anticancer Agents: From Natural to Synthetic Compounds
edited by and Roxana Popescu
submission deadline 30 Apr 2026 | 1 articles | Viewed by 351 | Submission Open
Keywords: bioactive molecules; natural products; synthetic compounds; molecular design; antimicrobial agents; anticancer agents; drug-resistant infections; drug discovery
(This special issue belongs to the Section Biochemistry)
Molecular Insights in Women’s Health: Advances in Gynecological Disease Mechanisms and Therapeutics
edited by
submission deadline 30 Apr 2026 | Viewed by 322 | Submission Open
Keywords: ART and IVF; prenatal diagnosis; infertility; minimally invasive surgery; robotic surgery; PCOS; endometriosis; menopause; AI
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Fibroblasts in the Regulation of Tissue Inflammation and Repair
edited by Rebeca Illescas Montes
submission deadline 30 Apr 2026 | 1 articles | Viewed by 276 | Submission Open
Keywords: fibroblast; wound healing; inflammation; tissue repair; immune– stromal crosstalk; extracellular matrix remodeling; myofibroblast; regenerative medicine; exosomes; biomaterials
(This special issue belongs to the Section Molecular Immunology)
Human Meningioma: Recent Developments
edited by Jason P. Sheehan, Yuki Shinya and Stylianos Pikis
submission deadline 30 Apr 2026 | Viewed by 275 | Submission Open
Keywords: meningioma; molecular pathogenesis; genomic alteration; radiogenomics; tumor microenvironment; biomarkers; neurosurgery; radiosurgery; translational neuroscience; artificial intelligence
(This special issue belongs to the Section Molecular Oncology)
Design, Synthesis, and Applications of Advanced Functional Materials
edited by
submission deadline 30 Apr 2026 | Viewed by 226 | Submission Open
Keywords: advanced functional materials; materials synthesis; nanomaterials; hybrid materials
(This special issue belongs to the Section Materials Science)
Exploring Molecular Progression in Inorganic Synthesis
edited by
submission deadline 30 Apr 2026 | Viewed by 226 | Submission Open
Keywords: inorganic synthesis; materials science; catalysis; energy materials; bioinorganic systems; organometallic compounds; supramolecular chemistry; molecular design
(This special issue belongs to the Section Materials Science)
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