Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Radiomics and Artificial Intelligence Applications in the Diagnosis of Brain Lesions
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 4990 | Submission Open
Keywords: brain lesions; biomarker; prognosis; diagnosis; radiomics; artificial intelligence
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Physiological Sound Processing for Medical Diagnostics: Innovations, Challenges, and Applications
edited by and Prabal Datta Barua
submission deadline 30 Sep 2026 | 2 articles | Viewed by 4953 | Submission Open
Keywords: heart sounds; lung sounds; cough analysis; sleep apnea and snoring; wearable devices; explainability and ethical AI; standardization and clinical validation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Laboratory Markers of Human Disease—2nd Edition
edited by
submission deadline 30 Sep 2026 | 5 articles | Viewed by 4917 | Submission Open
Keywords: laboratory biomarkers; genomics; proteomics; molecular diagnostics; clinical chemistry
(This special issue belongs to the Section Clinical Laboratory Medicine)
Diagnostics Advances in Peripheral Nerve Injuries
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 4663 | Submission Open
Keywords: peripheral nerve injuries; diagnosis challenges; magnetic resonance imaging (MRI); electromyography (EMG); brachial plexus injury; nerve trunk lesions; radicular lesions; nerve recovery assessment; advances in nerve imaging; EMG-guided treatment
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnosis, Treatment, and Management of Hair Disorders
edited by Neil Jairath and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 4628 | Submission Open
Keywords: hair loss; alopecia; management; cicatricial; diagnosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition submission deadline 30 Sep 2026 | 4 articles | Viewed by 4430 | Submission Open
Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma
(This special issue belongs to the Section Medical Imaging and Theranostics)
Contemporary Clinical Anatomy in Diagnostic Practice: Imaging, Artificial Intelligence, and Diagnostic Interpretation
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 4094 | Submission Open
Keywords: clinical anatomy; diagnostic interpretation; medical imaging; artificial intelligence; diagnostic accuracy; anatomical variability; translational diagnostics; radiological anatomy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advancing Blood-Based Diagnostics: Innovations, Challenges and Clinical Impact
edited by Sapha Shibeeb
submission deadline 30 Sep 2026 | 4 articles | Viewed by 3889 | Submission Open
Keywords: diagnostic biomarkers; analytical performance; test interpretability; prognostic markers; translational diagnostics; artificial intelligence in diagnostics; precision medicine; clinical decision-making
(This special issue belongs to the Section Clinical Laboratory Medicine)
Insights into Imaging Diagnosis of Heart Disease
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 3746 | Submission Open
Keywords: cardiovascular imaging including echocardiography and CTCA; cardiovascular imaging; echocardiography; cardiac magnetic resonance; myocardial perfusion imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Complex Digestive Diseases: Diagnosis and Management
edited by
submission deadline 30 Sep 2026 | 5 articles | Viewed by 3584 | Submission Open
Keywords: complex digestive diseases; precision diagnosis; advanced endoscopy; personalized management; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnosis, Treatment and Management of Gastrointestinal Diseases submission deadline 30 Sep 2026 | 3 articles | Viewed by 3499 | Submission Open
Keywords: gastrointestinal diseases; liver diseases; biomarkers in GI disease; imaging in GI diagnosis (CT, MRI, ultrasound); non-invasive diagnostic tools; GI Endoscopic procedures; treatment approaches; personalized medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Imaging-Guided Diagnosis and Precision Assessment in Spine and Joint Disorders
edited by Giuliano Lo Bianco, Timothy Deer and Kenneth B. Chapman
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3188 | Submission Open
Keywords: imaging-guided diagnostics; precision pain medicine; chronic pain; spine and joint disorders; artificial intelligence in imaging; radiomics and imaging biomarkers; neuromodulation and image-guided interventions
(This special issue belongs to the Section Medical Imaging and Theranostics)
Allergy and Asthma: Clinical Diagnostics and Management
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3158 | Submission Open
Keywords: allergy; asthma; precision medicine; biomarkers; airway inflammation; clinical diagnostics; biologic therapies; phenotyping; disease management; immunology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Ultrasound Imaging: Current Status and Future Perspectives submission deadline 30 Sep 2026 | 3 articles | Viewed by 3048 | Submission Open
Keywords: elastography; CEUS; fat quantification; radiomics/ultrasomics; point-of-care ultrasound
(This special issue belongs to the Section Medical Imaging and Theranostics)
Current Trends in Computed Tomography: Optimization and Clinical Practice
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 3001 | Submission Open
Keywords: computed tomography (CT); CT protocol optimization; radiation dose optimization; iterative reconstruction; deep learning reconstruction; artificial intelligence in CT; diagnostic reference levels (DRLs); clinical CT practice
(This special issue belongs to the Section Medical Imaging and Theranostics)
Research Updates in Vestibular Dysfunction: Diagnostic Breakthroughs
edited by and
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2986 | Submission Open
Keywords: vestibular disorders; vertigo; biomarkers; molecular diagnostics; vestibular compensation; Meniere’s disease; BPPV; vestibular migraine; PPPD; dizziness; balance
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advancing Medical Imaging with AI: From Cutting-Edge Algorithms to Clinical Integration
edited by
submission deadline 30 Sep 2026 | 3 articles | Viewed by 2882 | Submission Open
Keywords: artificial intelligence; medical imaging; deep learning; computer-aided diagnosis (CADx); diagnostic imaging; clinical validation; medical image analysis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Recent Advances in Hematology and Oncology, 2nd Edition
edited by Chohao Lee
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2870 | Submission Open
Keywords: hematological malignancies; lymphoma; leukemia; multiple myeloma; precision medicine; immunotherapy; genomics; targeted therapies
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in Pain Medicine: Diagnosis and Management
edited by Alessandro Dario
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2792 | Submission Open
Keywords: neuropathic pain; fibromialgia; low back pain; nociplastic pain; artificial intelligence in pain medicine; evidence-based consensus guidelines; pain measuring; cancer pain medicine; interventional pain medicine; topic analgesic for chronic pain; SPECT/CT scan
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Obstetrics in the 21st Century: New Challenges and Translational Perspectives in Diagnostics submission deadline 30 Sep 2026 | 1 articles | Viewed by 2662 | Submission Open
Keywords: obstetrics; high-risk pregnancies; ultrasound; magnetic resonance imaging; pathology; immunology; experimental; genomics; biomarkers; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Maternal-Fetal Medicine: Diagnosis, Prognosis and Clinical Features
edited by Antonio Braga
submission deadline 30 Sep 2026 | 4 articles | Viewed by 2617 | Submission Open
Keywords: maternal–fetal medicine; prenatal diagnosis; fetal ultrasound and doppler; prediction models; high-risk pregnancy; perinatal outcomes
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Gastrointestinal Pathology submission deadline 30 Sep 2026 | 3 articles | Viewed by 2596 | Submission Open
Keywords: gastroesophageal reflux disease; gastritis; dysplasia; gastric cancer; inflammatory bowel disease; microscopic colitis; microbiota; celiac disease; colorectal cancer
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Diagnostic Approaches for Otologic Diseases in Otolaryngology
edited by Sung-Won Choi
submission deadline 30 Sep 2026 | 3 articles | Viewed by 2582 | Submission Open
Keywords: otologic diseases; diagnostic methods; hearing loss; vestibular disorders; advanced imaging; audiovestibular testing
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diabetes Mellitus: Clinical Diagnostics and Management
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2578 | Submission Open
Keywords: diabetes mellitus; clinical diagnostics; biomarkers; precision medicine; glycemic control; digital health
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Multilayered Insights into Next-Generation Sequencing (NGS) and Endocrine Tumors/Malignancies: From Molecular Mechanisms to Precision Diagnosis
edited by and
submission deadline 30 Sep 2026 | Viewed by 2387 | Submission Open
Keywords: thyroid; adrenal; pituitary; parathyroid; germline; somatic; gene; molecular biology; diagnosis; hormone; gene
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Soft Tissue and Bone Sarcomas: Advances in Diagnosis, Treatment, and Prognosis
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 2383 | Submission Open
Keywords: soft tissue sarcomas; bone sarcomas; diagnosis; prognosis; biomarkers
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
EEG Analysis in Diagnostics, 2nd Edition
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2146 | Submission Open
Keywords: advanced EEG Techniques; the characterization of EEG signal patterns; the identification of EEG signal abnormalities; functional connectivity analysis in EEG; sleep studies based on EEG; EEG in epilepsy diagnosis and monitoring; neurofeedback and EEG in cognitive enhancement; event-related potentials in clinical EEG; understanding pathophysiology via EEG
(This special issue belongs to the Section Medical Imaging and Theranostics)
New Advances in Gastrointestinal Endoscopy
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 2085 | Submission Open
Keywords: artificial intelligence; bariatric endoscopy; gastrointestinal bleeding; endoscopic imaging; endoscopic resection; endoscopic ultrasonography; gastrointestinal tumor; third-space endoscopy
(This special issue belongs to the Section Biomedical Optics)
Diagnosis and Treatment of Kidney Disease—2nd Edition submission deadline 30 Sep 2026 | 2 articles | Viewed by 2049 | Submission Open
Keywords: kidney diseases; acute kidney injury; nephropathy; biomarkers; diagnosis; chronic renal failure
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Innovative Diagnostic Imaging Technology in Musculoskeletal Tumors
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1908 | Submission Open
Keywords: musculoskeletal tumors; diagnostic imaging; innovative technology; advanced imaging modalities; tumor classification; tumor staging; imaging protocols; image analysis techniques
(This special issue belongs to the Section Medical Imaging and Theranostics)
Ocular Surface Alterations in Eyelid Malpositions: Pathophysiology, Diagnostic Tools, and Therapeutic Approaches
edited by Massimiliano Serafino and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1868 | Submission Open
Keywords: lid malpositions and ocular surface disorders; dry eye syndrome; exposure keratopathy; tear film instability; anterior segment imaging; lid surgery outcomes
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advanced Diagnostics in Women's Health: From Biomarkers to Imaging
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 1851 | Submission Open
Keywords: women’s health diagnostics; biomarkers; medical imaging; ultrasound; risk stratification; early diagnosis; precision medicine; obstetrics and gynaecology; non-invasive diagnostics; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Autopsy Pathology's Paradigm Shift: Are AI and New Technologies Forging a New Era?
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1618 | Submission Open
Keywords: autopsy pathology; AI; artificial intelligence; immunohistochemistry; molecular pathology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Hematology Laboratory—2nd Edition
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1493 | Submission Open
Keywords: complete blood counts; leukocyte differential; reticulocyte indices; immature platelet fraction; cell population data; blood cell analyzers
(This special issue belongs to the Section Clinical Laboratory Medicine)
Innovations in Diagnosis and Management of Cardiovascular Diseases
edited by and José Luiz Barros Pena
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1480 | Submission Open
Keywords: diagnosis; artificial intelligence; cardiovascular diseases
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Frontier Exploration of Multimodal Imaging in Cardiac Rheumatic and Immune Diseases
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1469 | Submission Open
Keywords: myopericarditis; valvular heart disease; coronary artery disease; vasculitis vascular stenosis; vascular aneurysm; reynard phenomenon
Deep Learning Applications in Medical Image Analysis and Diagnosis
edited by Jorge M. Núñez-Córdoba
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1334 | Submission Open
Keywords: deep learning; machine learning; artificial intelligence; medical imaging; diagnostic imaging; clinical validation; accuracy
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Dental Imaging, 2nd Edition
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1273 | Submission Open
Keywords: dental imaging; optical coherence tomography; ultrasound; dental MRI; dental CT; cone-beam computed tomography; optical imaging; acoustic imaging; dental radiography; panoramic radiography; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Achievements in Oral and Maxillofacial Radiology
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1266 | Submission Open
Keywords: cone-beam computed tomography (CBCT); artificial intelligence (AI) in radiology; maxillofacial pathology detection and evaluation; image-guided surgery; radiation dose optimization; radiographic interpretation; virtual surgical planning; temporomandibular joint imaging; temporomandibular joint and temporal bone diagnostics; oral cancer detection and evaluation
(This special issue belongs to the Section Medical Imaging and Theranostics)
Optical Coherence Tomography in Ophthalmology: Advanced Diagnostics and Intraoperative Applications
edited by
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1260 | Submission Open
Keywords: optical coherence tomography; retinal diseases; glaucoma; intraoperative imaging; surgical guidance; diagnostic imaging; vascular imaging; anterior segment; microvasculature; blood flow
(This special issue belongs to the Section Medical Imaging and Theranostics)
Diagnosis and Management of Pulmonary Fibrosis
edited by Yi Wang
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1240 | Submission Open
Keywords: pulmonary fibrosis; idiopathic pulmonary fibrosis; interstitial lung disease; diagnosis; biomarkers; antifibrotic therapy; imaging; disease management
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Machine Learning Approaches for the Diagnosis of Sleep and Respiratory Disorders
edited by , Shyam Subramanian and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1025 | Submission Open
Keywords: diagnostics; artificial intelligence; sleep; respiratory disorders; healthcare
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
AI-Powered Medical Image Diagnosis: From Algorithm Development to Clinical Validation
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 943 | Submission Open
Keywords: artificial intelligence ; medical image diagnosis ; deep learning ; clinical validation ; diagnostic accuracy
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Applications of Optical Coherence Tomography in the Ocular Diagnosis: From the Tear Film to the Sclera 2.0 submission deadline 30 Sep 2026 | 1 articles | Viewed by 851 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; corneal curvature; tear film; central corneal thickness; glaucoma; anterior chamber; iris angiography; macular thickness; choroidal thickness; axial length measurement; retinal vascular plexuses; choroidal vasculature; macular surgery
(This special issue belongs to the Section Biomedical Optics)
Periodontal Disease: Diagnosis and Management, 2nd Edition submission deadline 30 Sep 2026 | 1 articles | Viewed by 770 | Submission Open
Keywords: periodontal disease ; periodontitis ; management ; diagnosis ; biomarker ; periodontology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Pediatric Musculoskeletal Radiology Diagnosis: From Imaging Signs to Clinical Decisions
edited by Dhouib Amira
submission deadline 30 Sep 2026 | 1 articles | Viewed by 681 | Submission Open
Keywords: pediatric bone disorders; inflammatory bone disease; musculoskeletal infection; imaging signs; advanced MRI techniques
(This special issue belongs to the Section Medical Imaging and Theranostics)
Laboratory Diagnosis of Cardiovascular Diseases
edited by Ibrahim A. Hashim
submission deadline 30 Sep 2026 | 1 articles | Viewed by 601 | Submission Open
Keywords: laboratory diagnostics; cardiovascular diseases; biomarkers; metabolomics; point-of-care testing; artificial intelligence
(This special issue belongs to the Section Clinical Laboratory Medicine)
Clinical Advances in Diagnosis and Prognosis of Urological Diseases
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 584 | Submission Open
Keywords: urological diagnostics; prognostic biomarkers; artificial intelligence in urology; precision medicine; liquid biopsy; advanced imaging; prostate cancer; bladder cancer; kidney cancer; clinical risk stratification
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Feature Review Papers in Histopathology
edited by Dong Ren
submission deadline 30 Sep 2026 | Viewed by 578 | Submission Open
Keywords: histopathological features; histologic subtypes; diagnostic dilemma and pitfall; ancillary testing; tumor pathogenesis
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Clinical Updates in Diagnosis and Management of Thrombocytopenia
edited by Maria Eva Mingot-Castellano and Cristina Pascual-Izquierdo
submission deadline 30 Sep 2026 | Viewed by 561 | Submission Open
Keywords: ITP; bleeding; thrombosis; anticoagulant; antiplatelet
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
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