Advances in Hematology Laboratory—2nd Edition
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Laboratory Medicine".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 94
Special Issue Editor
Interests: medicine laboratory; clinical analysis technology; robotics in hematology; iron and anemia; erythropoiesis; glycohemoglobin; infection Inflammation; health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Complete blood counts (CBCs) and leukocyte differentials are among the most frequently requested laboratory tests. These analyses are highly automated, and the evolution of automation in the hematology laboratory has enabled not only high throughput, greater reliability, and accuracy in the results, but also, as automated hematology systems become more sophisticated with the introduction of new physical principles for cellular analysis, a generation of new parameters to characterize blood cells in more detail. Several parameters have been introduced to CBCs, such as nucleated red blood cells, immature granulocytes, immature platelet fraction, and new parameters for the detection of ineffective erythropoiesis (reticulocyte hemoglobin, red cell subsets). Leucocyte morphometric parameters (cell population data) aid in the preliminary diagnosis of diseases (i.e., differentiating between abnormal lymphocytes in leukemia and viral conditions) and could be useful to ascertain infection and sepsis, and the discrimination of the etiology.
Different technologies can be used to enumerate platelets, and modern counters can provide not only platelet count, but also derived indices relating to the morphology, size, or cytoplasm complexity, related to their functional activity.
The primary aim of this Special Issue is to update the information on the new parameters reported along with CBCs and leukocyte differentials to review the possible clinical applications of these parameters provided by modern hematologic instruments.
Dr. Eloisa Urrechaga
Guest Editor
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Keywords
- complete blood counts
- leukocyte differential
- reticulocyte indices
- immature platelet fraction
- cell population data
- blood cell analyzers
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