Advances in Diagnostic Approaches for Otologic Diseases in Otolaryngology

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 548

Special Issue Editor


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Guest Editor
Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea
Interests: hearing loss; eustachian tube; bilateral vestibulopathy

Special Issue Information

Dear Colleagues,

Otologic diseases comprise a broad range of disorders involving the external, middle, and inner ear and are a major cause of hearing loss, vertigo, tinnitus, and balance dysfunction worldwide. Accurate and timely diagnosis is essential for appropriate management.

Recent advances in diagnostic technologies have substantially improved the evaluation of otologic disorders. High-resolution imaging techniques, including advanced temporal bone computed tomography and inner ear magnetic resonance imaging, now allow more precise anatomical and pathological assessment. In parallel, objective auditory and vestibular function tests—such as wideband tympanometry, electrocochleography, vestibular evoked myogenic potentials, and video head impulse testing—have enhanced functional evaluation across a wide spectrum of otologic diseases. Moreover, emerging diagnostic approaches incorporating molecular biomarkers, genetic testing, and artificial intelligence-based analysis are paving the way toward precision diagnosis and personalized management in otology.

This Special Issue aims to present recent advances and future perspectives in the diagnosis of otologic diseases. We welcome original research articles, comprehensive reviews, and technical studies that address innovative diagnostic methods, multimodal assessment strategies, and translational approaches that bridge basic research and clinical practice, offering an updated overview of evolving diagnostic paradigms in otology.

Dr. Sung-Won Choi
Guest Editor

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Keywords

  • otologic diseases
  • diagnostic methods
  • hearing loss
  • vestibular disorders
  • advanced imaging
  • audiovestibular testing

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Published Papers (1 paper)

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Research

12 pages, 920 KB  
Article
Validation of NB CE-Chirps in the Diagnosis of Superior Semicircular Canal Dehiscence Syndrome
by Quentin Mat, Christophe Lelubre, Antonino Maniaci, Stéphane Gargula, Giannicola Iannella, Jerome R. Lechien and Sophie Tainmont
Diagnostics 2026, 16(6), 868; https://doi.org/10.3390/diagnostics16060868 - 14 Mar 2026
Viewed by 348
Abstract
Background/Objectives: The aim of this study was to assess NB CE-Chirps for diagnosing Superior Semicircular Canal Dehiscence Syndrome (SSCDS) with cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs), and to compare them with Tone Bursts (TBs). Methods: Nine subjects [...] Read more.
Background/Objectives: The aim of this study was to assess NB CE-Chirps for diagnosing Superior Semicircular Canal Dehiscence Syndrome (SSCDS) with cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs), and to compare them with Tone Bursts (TBs). Methods: Nine subjects diagnosed with SSCDS were included (four men/five women, median = 61 years, range = 31–79 years). Intensity thresholds at 500 Hz were investigated with both stimuli. A response was also sought when NB CE-Chirps and TBs were delivered at 4000 Hz for c and oVEMPs. Results: Both 500 Hz TBs and 500 Hz NB CE-Chirps significantly differentiated affected ears from healthy ears for cVEMPs (p < 10−3 in both cases) and oVEMPs (p < 10−3 in both cases). Furthermore, we observed significantly lower intensity thresholds in SSCDS ears with 500 Hz NB CE-Chirps than with 500 Hz TBs for both cVEMPs (p < 10−3) and oVEMPs (p = 0.036). Regarding the response rate at 4000 Hz, only TBs consistently showed a response in 100% of cases for the affected ears, with no response in healthy ears for both cVEMPs and oVEMPs. However, there was no significant difference between the response rates obtained at 4000 Hz using TBs and NB CE-Chirps in affected ears (p = 1.000 for cVEMPs and p = 1.000 for oVEMPs). Conclusions: Searching for intensity thresholds with NB CE-Chirps 500 Hz in cVEMPs and oVEMPs is an effective method for diagnosing SSCDS, likely with better frequency specificity than with 500 Hz TBs. Stimulation at 4000 Hz with both TBs and NB CE-Chirps appears to be a promising test for easily screening this syndrome, reducing both sound exposure and the duration of the examination. The possibility to reduce rise time in 4000 Hz TBs may favor this stimulus over NB CE-Chirps at this frequency for this disease. These results should be confirmed in larger cohorts including patients with more severe forms. Full article
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