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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Role of BCL-2 Family Proteins in Cancer: Therapeutic Advancements and Challenges

edited by Sajid Khan

submission deadline 31 Aug 2025 | Viewed by 213 | Submission Open

Keywords: BCL-2 family proteins; apoptosis; BH3 mimetics; thrombocytopenia; proteolysis-targeting chimeras; drug resistance; combination therapy; targeted drug delivery

(This special issue belongs to the Section Cancer Therapy)

Lymphoid and Myeloid Leukemias—Current Progress in Biology and Treatment

edited by Ewa Robak and

Tadeusz Robak

submission deadline 31 Aug 2025 | Viewed by 209 | Submission Open

Keywords: acute myeloid leukemia; promyelocytic leukemia; myelomonocytic leukemia; chronic lymphocytic leukemia; hairy cell leukemia; prolymphocytic leukemia; large granular lymphocyte leukemia; acute lymphoblastic leukemia

(This special issue belongs to the Section Molecular Cancer Biology)

CAR T-Cell Therapy and Multiple Myeloma

edited by Jo Caers

submission deadline 31 Aug 2025 | Viewed by 206 | Submission Open

Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Progress in Modelling, Understanding of Cellular Biology of Prostate Cancer

edited by Benyi Li

submission deadline 31 Aug 2025 | Viewed by 202 | Submission Open

Keywords: prostate cancer; cellular biology; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Signaling Networks Controlling Ovarian Cancer Progression and Response to Therapy

edited by

Luca Tamagnone

and Roberta Mastrantonio

submission deadline 31 Aug 2025 | Viewed by 167 | Submission Open

Keywords: ovarian cancer; patient-derived models; mesothelium; ascites; immunotherapy; chemotherapy; drug resistance; metastasis; peritoneum; p53; BRCA; signaling pathway; metabolism

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Neuroendocrine Neoplasms—Second Edition

edited by Costanza Chiapponi

submission deadline 31 Aug 2025 | Viewed by 166 | Submission Open

Keywords: neuroendocrine neoplasms (NENs); neuroendocrine carcinomas (NECs); carcinoid syndrome; medullary thyroid cancer (MTC); gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs); pheochromocytoma/paraganglioma; carcinoids; Merkel cell carcinoma (MCC); small intestinal neuroendocrine neoplasms (siNENs); somatostatin analogs; peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Cancer Pathophysiology)

Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition

edited by Claudio Spinelli and Marco Ghionzoli

submission deadline 31 Aug 2025 | Viewed by 148 | Submission Open

Keywords: thyroid nodule; thyroid cancer; guidelines; surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Genomic Analysis of Breast Cancer

edited by

Hiroshi Tada

and

Hiroko Masuda

submission deadline 31 Aug 2025 | Viewed by 96 | Submission Open

Keywords: breast cancer; comprehensive genomic profiling; molecular-matched therapy

(This special issue belongs to the Section Cancer Pathophysiology)

MicroRNA in Cancer: From Molecular Mechanisms to Therapeutic Applications

edited by Girish Shukla and

Sivakumar Vijayaraghavalu

submission deadline 31 Aug 2025 | Viewed by 91 | Submission Open

Keywords: microRNA (miRNA) therapeutics; cancer biomarkers; oncogenic and tumor-suppressive miRNAs; miRNA delivery systems; precision oncology

(This special issue belongs to the Section Cancer Biomarkers)

AI-Based Applications in Cancers

edited by

Xia Jiang

submission deadline 31 Aug 2025 | Viewed by 35 | Submission Open

Keywords: AI; machine learning; deep learning; Bayesian networks; causal learning; LLM; cancer

(This special issue belongs to the Section Cancer Informatics and Big Data)

Advances in the Management of Pelvic Tumors

edited by

Maria Chiara Sighinolfi

and Giorgia Gaia

submission deadline 1 Sep 2025 | 6 articles | Viewed by 10569 | Submission Open

Keywords: pelvic cancer; prostate cancer; bladder cancer; uterine cancer; ovarian cancer; rectal cancer; anal cancer

(This special issue belongs to the Section Cancer Therapy)

Health Services Research in Cancer Care

edited by

Francesco Giusti

and

Carmen Martos

submission deadline 1 Sep 2025 | 4 articles | Viewed by 7681 | Submission Open

Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

The Role of Aromatase Inhibitors in Breast Cancer Treatment

edited by

Chandra Bhushan Mishra

submission deadline 1 Sep 2025 | 2 articles | Viewed by 2667 | Submission Open

Keywords: aromatase inhibitors; breast cancer; enzyme aromatase; estrogen

(This special issue belongs to the Section Cancer Therapy)

New Perspectives in the Treatment of Thoracic Cancers

edited by

Francesco Londero

and

Francesco Guerrera

submission deadline 1 Sep 2025 | 1 articles | Viewed by 549 | Submission Open

Keywords: lung cancer; pulmonary metastases; thymic malignancies; malignant mesothelioma; immunotherapy; target therapy; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Recent Advances in Radiological Imaging for Head and Neck Squamous Cell Carcinoma

edited by Mintu Nath and

Fergus McKiddie

submission deadline 1 Sep 2025 | Viewed by 218 | Submission Open

Keywords: head and neck squamous cell carcinoma; computed tomography (CT); positron emission tomography (PET); PET-CT; radiological imaging; image processing; image segmentation; diagnosis; treatment modalities; prediction and prognostic models; mathematical and statistical models; machine learning and deep learning techniques

(This special issue belongs to the Section Methods and Technologies Development)

Genetic and Epigenetic Markers in Gliomas: Expanding the Horizon in Diagnosing, Predicting, and Treating Gliomas

edited by Wai Chin Chong

submission deadline 1 Sep 2025 | Viewed by 86 | Submission Open

Keywords: glioma; genetic markers; epigenetic markers; predictive biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Cancer Biology)

Drug Utilization, Safety and Effectiveness of Anti-Cancer Drugs for Solid Tumors: A Focus on Special Populations

edited by

Andrea Spini

and

Sandra Donnini

submission deadline 5 Sep 2025 | 4 articles | Viewed by 10063 | Submission Open

Keywords: drug utilization; safety; effectiveness; anti-cancer drugs; cancer; tumor; observational studies; pharmacoepidemiology; observational study; pharmacovigilance; spontaneous reporting system; children; pediatric; elderly; female; women; gender; minorities; pregnancy; immunotherapy; chemotherapy; target-therapy; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Surgical Advances in the Treatment of Gliomas: Preserving Function and Quality of Life

edited by Francesco Vergani and José Pedro Lavrador

submission deadline 7 Sep 2025 | 2 articles | Viewed by 2303 | Submission Open

Keywords: neuro-oncology; brain mapping; neuroimaging; intraoperative neuro-monitoring; functional MRI; transcranial magnetic stimulation; neurorehabilitation

(This special issue belongs to the Section Cancer Therapy)

Steps towards the Clinics in Spatially Fractionated Radiation Therapy

edited by

Stefan Bartzsch

submission deadline 10 Sep 2025 | 6 articles | Viewed by 12827 | Submission Open

Keywords: microbeams; minibeams; spatially fractionated radiation therapy; dosimetry; treatment planning; radiation sources; synchrotrons; high dose rates; preclinical studies; veterinary trials

(This special issue belongs to the Section Clinical Research of Cancer)

Outcomes in Glioblastoma Patients: From Diagnosis to Palliation

edited by

Alba Scerrati

and Giorgio Mantovani

submission deadline 10 Sep 2025 | 5 articles | Viewed by 10766 | Submission Open

Keywords: high-grade glioma; outcome assessment; prognostic factors; neuro-oncology; glioblastoma

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Tumor-Initiating Cells in Breast Cancer: From Bench to Bedside

edited by

Spiros Vlahopoulos

submission deadline 10 Sep 2025 | 1 articles | Viewed by 3110 | Submission Open

Keywords: breast cancer; cancer stem cell; tissue microenvironment; epithelial– mesenchymal transition; mesenchymal– epithelial transition

(This special issue belongs to the Section Tumor Microenvironment)

Advances in Exosomes and Cancer Biomarkers

edited by

Nathan Wall

submission deadline 12 Sep 2025 | Viewed by 165 | Submission Open

Keywords: exosomes; cancer biomarkers; liquid biopsy; tumor microenvironment; molecular diagnosis

(This special issue belongs to the Section Cancer Biomarkers)

Molecular Imaging in Oncology: Recent Advances

edited by

Lioe-Fee de Geus-Oei

submission deadline 15 Sep 2025 | 12 articles | Viewed by 29195 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET; oncology; cancer; SPECT; precision medicine; personalized medicine; biomarker; targeted radionuclide therapies; personalized dosimetry

(This special issue belongs to the Section Methods and Technologies Development)

Cancer Genetics and Epigenetics: Their Roles and Clinical Implications

edited by

Armita Bahrami

and

Ying Qing

submission deadline 15 Sep 2025 | 5 articles | Viewed by 15321 | Submission Open

Keywords: cancer genetics; cancer epigenetics; carcinogenesis; cancer prognosis; cancer therapeutics; genetic mutations; DNA methylation; histone modifications; RNA methylation

(This special issue belongs to the Section Molecular Cancer Biology)

Dermoscopy in Skin Cancer

edited by

Elisa Zavattaro

and

Paola Savoia

submission deadline 15 Sep 2025 | 8 articles | Viewed by 11907 | Submission Open

Keywords: dermoscopy; skin cancer; differential diagnosis; dermoscopy patterns; non-invasive diagnostic tool

(This special issue belongs to the Section Methods and Technologies Development)

Emerging Trends in Global Cancer Epidemiology: 2nd Edition

edited by Syed Ahsan Raza

submission deadline 15 Sep 2025 | 5 articles | Viewed by 9403 | Submission Open

Keywords: cancer epidemiology; global cancer research; incidence; prevention and control strategies; risk factors; data sources and methods; social and environmental impact; population health; emerging trends; survival and mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Radioligand Therapy (RLT) in Neuroendocrine Neoplasms

edited by

Grzegorz Kamiński

submission deadline 15 Sep 2025 | 4 articles | Viewed by 7032 | Submission Open

Keywords: neuroendocrine neoplasms (NENs); neuroendocrine tumors (NETs); radioligand therapy (RLT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Cancer Therapy)

Advances in Interventional Oncologic Therapies

edited by Edward W. Lee and

Dong Il Gwon

submission deadline 15 Sep 2025 | 3 articles | Viewed by 6824 | Submission Open

(This special issue belongs to the Section Cancer Therapy)

Multi-Omics Analysis in the Study of Carcinogenesis

edited by

Dimiter Avtanski

submission deadline 15 Sep 2025 | 3 articles | Viewed by 5815 | Submission Open

Keywords: carcinogenesis; cancer initiation and progression; oncology research; multi-omics analyses; genomics; transcriptomics; proteomics; metabolomics

(This special issue belongs to the Section Cancer Pathophysiology)

Skin Cancers of the Head and Neck

edited by

Cherie-Ann Nathan

and

Shaun A. Nguyen

submission deadline 15 Sep 2025 | 2 articles | Viewed by 4362 | Submission Open

Keywords: non-melanoma skin cancer (NMSC); squamous cell carcinoma (SCC); basal cell carcinoma (BCC); melanoma; genomic profiling; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Artificial Intelligence and MRI Characterization of Tumors: 2nd Edition

edited by

Eliodoro Faiella

Paolo Soda

Domiziana Santucci

and Ermanno Cordelli

submission deadline 15 Sep 2025 | 1 articles | Viewed by 4146 | Submission Open

Keywords: cancer; MRI; CT; PET 18F-FDG; PET/CT scintigraphy; artificial intelligence (AI); radiomics convolutional neural networks (CNN)

(This special issue belongs to the Section Methods and Technologies Development)

Hematopoietic Stem Cell Transplant in Hematological Malignancies

edited by

Luisa Giaccone

and Alessandro Cignetti

submission deadline 15 Sep 2025 | 2 articles | Viewed by 4057 | Submission Open

Keywords: stem cell transplant; graft-versus-host disease; conditioning regimen; prophylaxes; immunology; donors; hematological disease

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Survivorship: Challenges and Innovations from Treatment to Long-Term Care

edited by Médéa Locquet

submission deadline 15 Sep 2025 | 2 articles | Viewed by 2152 | Submission Open

Keywords: breast cancer survivorship; cancer treatments; late effects: societal impact; supportive care; psychosocial well-being; cancer treatment optimization; interventions

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Genetics of Endometrial Cancer: Latest Insights and Innovations in Research

edited by Ekaterina Olkhov-Mitsel

submission deadline 15 Sep 2025 | 1 articles | Viewed by 2121 | Submission Open

Keywords: endometrial carcinoma; genomic landscape; genetic aberrations; molecular biomarkers; hereditary predisposition to cancer; next-generation sequencing; targetable mutations; somatic mutations

(This special issue belongs to the Section Methods and Technologies Development)

Oxidative Stress and Cancer: Possible Beneficial and Antioxidant Strategies (2nd Edition)

edited by

Rita Rezzani

submission deadline 15 Sep 2025 | 1 articles | Viewed by 1471 | Submission Open

Keywords: oxidative; stress; antioxidant; melatonin; carcinogenesis

(This special issue belongs to the Section Molecular Cancer Biology)

Biomarkers and Targeted Therapy in Malignant Pleural Mesothelioma

edited by

Susana Cedrés

submission deadline 15 Sep 2025 | 2 articles | Viewed by 1389 | Submission Open

Keywords: malignant mesothelioma; target therapy; biomarkers

(This special issue belongs to the Section Cancer Biomarkers)

MicroRNA and Cancer Immunology

edited by

Behzad Mansoori

submission deadline 15 Sep 2025 | Viewed by 792 | Submission Open

Keywords: microRNA; miRNA; tumor microenvironment; biomarkers; cancer immunology; cancer treatment; therapeutic target; tumor angiogenesis; tumor metastasis

(This special issue belongs to the Section Tumor Microenvironment)

Emergencies in Gastrointestinal Surgical Oncology

edited by

Fausto Rosa

Carlo Alberto Schena

and

Nicola De'Angelis

submission deadline 15 Sep 2025 | Viewed by 419 | Submission Open

Keywords: surgical oncology; emergencies; emergency surgery; acute care surgery; palliation; futility in surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in the Treatment of Relapsed and Refractory Multiple Myeloma: Novel Agents, Immunotherapies and Beyond: 2nd Edition

edited by

Klaus Podar

and

Xavier Leleu

submission deadline 15 Sep 2025 | 1 articles | Viewed by 401 | Submission Open

Keywords: myeloma relapse setting; drug development; treatment sequences; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Role of Epstein–Barr Virus in Human Cancers

edited by

Lucia Mundo

, Cristiana Bellan and

Stefano Lazzi

submission deadline 15 Sep 2025 | Viewed by 253 | Submission Open

Keywords: Epstein– Barr virus; cancer; EBV-driven malignancies; tumour microenvironment; immune response; immunotherapy

(This special issue belongs to the Section Infectious Agents and Cancer)

Endothelial Cells in Inflammation, Tissue Repair, Ageing and Cancer: 2nd Edition

edited by

Constantinos Mikelis

submission deadline 15 Sep 2025 | Viewed by 186 | Submission Open

Keywords: ageing; angiogenesis; cancer; cytokines; endothelial cells; growth factors; inflammation; tissue repair

(This special issue belongs to the Section Tumor Microenvironment)

Advances in T-Cell Immunotherapy for Acute Myeloid Leukemia

edited by

Pau Montesinos

submission deadline 15 Sep 2025 | Viewed by 118 | Submission Open

Keywords: T-cell engager; AML; minimal residual disease; relapse/refractory; high-risk MDS; toxicity; antigen; CAR-T cell; myelosuppression; cytokine release syndrome

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy

edited by

Beata Jabłońska

submission deadline 17 Sep 2025 | 1 articles | Viewed by 1043 | Submission Open

Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy

(This special issue belongs to the Section Cancer Therapy)

The Clinical Trials and Management of Acute Myeloid Leukemia

edited by

Margaret T. Kasner

submission deadline 19 Sep 2025 | 4 articles | Viewed by 6947 | Submission Open

Keywords: acute myeloid leukemia; clinical trials; translational research; targeted therapies; novel agents

(This special issue belongs to the Section Clinical Research of Cancer)

New Insights into Urologic Oncology

edited by Justin H. Hwang and Song Yi Bae

submission deadline 20 Sep 2025 | 17 articles | Viewed by 31065 | Submission Open

Keywords: urologic cancer; therapeutic resistance; heterogeneity; genomic alterations; lineage plasticity; epigenetic reprogramming

(This special issue belongs to the Section Cancer Therapy)

Research Progress of Cutaneous Squamous and Basal Cell Carcinomas (Volume II)

edited by

Moran Amit

Frederico O. Gleber-Netto

and Neil D. Gross

submission deadline 20 Sep 2025 | 5 articles | Viewed by 13027 | Submission Open

Keywords: tumor immune microenvironment; cutaneous squamous cell carcinoma; immunodeficiency; biomarkers; therapeutics; ultraviolet

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Communication and Accessibility in the Tumor Microenvironment as a Therapeutic Target

edited by

Gema Jiménez-González

and Carmen Griñán-Lisón

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7803 | Submission Open

Keywords: tumor microenvironment; cellular communication; tumor secretome; signaling; extracellular matrix; cancer treatment; targeted treatment

(This special issue belongs to the Section Cancer Therapy)

Immunotherapy of Non-Small Cell Lung Cancer

edited by Aakash P. Desai

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2964 | Submission Open

Keywords: antibody drug conjugates; ADCs; non-small cell lung cancer; NSCLC; interstitial lung disease; ILD; TROP2; ERBB2

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Multimodality Imaging for More Precise Radiotherapy

edited by

Valeria Faccenda

Denis Panizza

and Stefano Arcangeli

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2866 | Submission Open

Keywords: multimodality imaging; radiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Molecular Pathology Insights in Thyroid Cancer

edited by Salma Khan

submission deadline 20 Sep 2025 | Viewed by 149 | Submission Open

Keywords: non-coding RNAs; epigenetics; biomarkers; BRAF mutations; RAS mutations; targeted therapy; precision medicine; genomic profiling; tumor heterogeneity; therapeutic resistance

(This special issue belongs to the Section Cancer Pathophysiology)

Displaying special issue 401-450 on page 9 of 22.

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