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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanistic Insights and Therapeutic Advances in the Prostate Tumor Microenvironment

edited by Omar E. Franco

submission deadline 28 Feb 2026 | Viewed by 74 | Submission Open

Keywords: prostate stromal cells; tumor microenvironment; stromal– epithelial interactions; extracellular matrix; tumor immune evasion; metabolic reprogramming; hypoxia; single-cell data analysis; in vitro/in vivo model systems; carcinoma-associated fibroblasts (CAFs)

(This special issue belongs to the Section Tumor Microenvironment)

The Role of Regucalcin in Cancer

edited by

Masayoshi Yamaguchi

submission deadline 1 Mar 2026 | 2 articles | Viewed by 3449 | Submission Open

Keywords: cancer suppressor protein; cell signaling; metabolic regulation; transcription factor; cell proliferation; cell death; drug development; cancer therapy

(This special issue belongs to the Section Tumor Microenvironment)

Lynch Syndrome (HNPCC): Symptoms, Causes, and Outlooks

edited by

Francesca Duraturo

submission deadline 1 Mar 2026 | Viewed by 612 | Submission Open

Keywords: Lynch syndrome; genotype– phenotype correlation; highly immunogenic frame-shift neo-peptides; immunotherapy; mismatch repair genes; unclassified genetic variants; new role of MMR proteins; miRNAs; functional assay MMR deficiency

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Brain and Spinal Cord Tumors: Symptoms, Diagnosis and Treatment—2nd Edition

edited by

Alberto Feletti

and

Takashi Sugawara

submission deadline 1 Mar 2026 | Viewed by 171 | Submission Open

Keywords: brain; spinal cord; primary tumors; metastases; imaging; neuro-oncology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Castration-Resistant Prostate Cancer: Progress and Promise: 2nd Edition

edited by

Shiv Verma

Vaibhav Singh

and

Man Mohan

submission deadline 1 Mar 2026 | Viewed by 131 | Submission Open

Keywords: castrate-resistant prostate cancer (CRPC); prostate cancer; treatment; a new therapy; drug-resistant; marker genes; bone metastasis; androgen receptor (AR); enzalutamid; e abiraterone acetate; Docetaxel

(This special issue belongs to the Section Cancer Therapy)

Quality of Care for Patients with Head and Neck Cancer

edited by Khara Marissa Sauro

submission deadline 1 Mar 2026 | Viewed by 86 | Submission Open

Keywords: patient safety; treatment delays; healthcare resource use; effectiveness; health economics; continuity of care; outcomes research

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Prognostic and Predictive Markers in Gynecological Cancers

edited by Anna Plotkin

submission deadline 1 Mar 2026 | Viewed by 79 | Submission Open

Keywords: biomarker; gynecological cancer; management; prognostic marker; predictive marker; personalized medicine

(This special issue belongs to the Section Cancer Biomarkers)

Fertility Preservation and Hormonal Health in Oncology

edited by

Amelia Barcellini

and

Chiara Cassani

submission deadline 6 Mar 2026 | 2 articles | Viewed by 1049 | Submission Open

Keywords: oncofertility; fertility preservation; hormonal health; cancer survivorship; reproductive oncology

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Immunotherapy for Skin Cancers

edited by

Reinhard Dummer

and Lara Valeska Maul-Duwendag

submission deadline 10 Mar 2026 | 3 articles | Viewed by 6512 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; merkel cell carcinoma; kaposi sarcoma; cutaneous angi-osarcoma; immune checkpoint; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

RAS Proteins and Their Regulators in Human Cancer

edited by Zhiwei Zhou

submission deadline 10 Mar 2026 | Viewed by 189 | Submission Open

Keywords: RAS; RAS regulators; RAS-driven diseases; RAS-targeting therapy

(This special issue belongs to the Section Cancer Therapy)

Study on Clinical Treatment of Brain Tumors

edited by Shinya Watanabe

submission deadline 13 Mar 2026 | 3 articles | Viewed by 6660 | Submission Open

Keywords: brain tumors; clinical treatment; anti-tumor drugs; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Molecular Pathology of Brain Tumors

edited by Ho-Keung NG

submission deadline 15 Mar 2026 | 10 articles | Viewed by 31062 | Submission Open

Keywords: molecular pathology; brain tumors; AI; biomarkers; histopathology

(This special issue belongs to the Section Molecular Cancer Biology)

State of the Art: Cardiothoracic Tumors

edited by

Calvin Sze Hang Ng

and Panagiotis Tasoudis

submission deadline 15 Mar 2026 | 5 articles | Viewed by 12508 | Submission Open

Keywords: lung cancer; non-small cell lung cancer; esophageal cancer; diagnostic imaging; robotic-assisted thoracoscopic surgery; video-assisted thoracoscopic surgery; immunotherapy; radiotherapy; molecular oncology; lung cancer screening

(This special issue belongs to the Section Cancer Therapy)

Breast Cancer Survivorship: Challenges and Innovations from Treatment to Long-Term Care

edited by Médéa Locquet

submission deadline 15 Mar 2026 | 8 articles | Viewed by 8092 | Submission Open

Keywords: breast cancer survivorship; cancer treatments; late effects: societal impact; supportive care; psychosocial well-being; cancer treatment optimization; interventions

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Novel Approaches to the Management of Patients with Gastrointestinal Tumors

edited by Javier Rodriguez and Ignacio Matos García

submission deadline 15 Mar 2026 | 3 articles | Viewed by 4006 | Submission Open

Keywords: clinical management; gastric cancer; colorectal cancer; predictive factors; novel therapies; artificial intelligence

(This special issue belongs to the Section Methods and Technologies Development)

Robot-Assisted Surgery for Urologic Cancer

edited by Gabriele Sorce, Francesco Pellegrino and Ettore Di Trapani

submission deadline 15 Mar 2026 | 3 articles | Viewed by 3603 | Submission Open

Keywords: robot-assisted surgery; urologic oncology; minimally invasive surgery; prostate cancer surgery; kidney cancer surgery; bladder cancer surgery; robotic platforms; robotic surgery training

(This special issue belongs to the Section Cancer Therapy)

Advances in Artificial Intelligence Methodologies and Applications in Cancer

edited by Jennifer G. Le-Rademacher and

Nicholas Larson

submission deadline 15 Mar 2026 | 3 articles | Viewed by 3563 | Submission Open

Keywords: artificial intelligence (AI); AI tools; cancer research; diagnostic tools; medical imaging; biomarkers; ethical considerations; patient care

(This special issue belongs to the Section Methods and Technologies Development)

Advances in the Treatment of Relapsed and Refractory Multiple Myeloma: Novel Agents, Immunotherapies and Beyond: 2nd Edition

edited by

Klaus Podar

and

Xavier Leleu

submission deadline 15 Mar 2026 | 2 articles | Viewed by 3108 | Submission Open

Keywords: myeloma relapse setting; drug development; treatment sequences; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Radiotherapy for Sarcoma

edited by Safia K. Ahmed and Miranda Lam

submission deadline 15 Mar 2026 | 3 articles | Viewed by 2578 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; advanced sarcoma; radiation therapy; particle therapy; multidisciplinary sarcoma care

(This special issue belongs to the Section Cancer Therapy)

Advances in Lung Cancer Treatment Strategies

edited by

Alessandro Gonfiotti

and

Alice Ravasin

submission deadline 15 Mar 2026 | 2 articles | Viewed by 1370 | Submission Open

Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors; chemoimmunotherapy; target therapy; biomarkers; non-small cell lung cancer; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Renal Cell Carcinoma: Genetics, Surgical Management, and Systemic Therapy

edited by Alejandro Remigio Rodríguez, Stênio C. Zequi and Maxwell Sandberg

submission deadline 15 Mar 2026 | 2 articles | Viewed by 952 | Submission Open

Keywords: renal cell carcinoma; robotics; laparoscopy; systemic therapy; genetics; surgery; urology; disparities; tumor thrombus; cryotherapy; global health

(This special issue belongs to the Section Methods and Technologies Development)

Endometrial Cancer Therapy: Foundations and Future Directions

edited by

Àngeles Rovirosa

and

Meritxell Arenas

submission deadline 15 Mar 2026 | 1 articles | Viewed by 557 | Submission Open

Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Stress, Epigenetic Regulation, and DNA Damage: Insights into Cancer Development and Therapeutic Challenges

edited by Yanying Huo

submission deadline 15 Mar 2026 | Viewed by 161 | Submission Open

Keywords: ROS; oxidative stress; metabolic stress; DNA damage repair; genomic instability; cancer

(This special issue belongs to the Section Cancer Pathophysiology)

Treatment of Acute Kidney Injury in Cancer Patients: From Theory to Practice

edited by

Umut Selamet

and Shveta S. Motwani

submission deadline 15 Mar 2026 | Viewed by 149 | Submission Open

Keywords: immune check point inhibitor related nephritis; MGRS; CART cell therapy; stem cell transplant; TMA; BK nephropathy; cisplatin nephropathy

(This special issue belongs to the Section Cancer Therapy)

Development of Hepatitis C Virus-Related Cancers

edited by

Anna linda Zignego

submission deadline 15 Mar 2026 | Viewed by 85 | Submission Open

Keywords: hepatitis C virus (HCV); hepatocellular carcinoma (HCC); extrahepatic malignancies; lymphoproliferative disorders; viral oncogenesis; chronic inflammation and cancer; direct-acting antivirals (DAAs); cancer surveillance in HCV patients

(This special issue belongs to the Section Clinical Research of Cancer)

Health Economic and Policy Issues Regarding Cancer

edited by Aviad Tur-Sinai

submission deadline 16 Mar 2026 | 2 articles | Viewed by 2247 | Submission Open

Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Onco-Nephrology: From Molecular to Clinical Studies

edited by

Hans Kristian Lorenzo

submission deadline 16 Mar 2026 | Viewed by 515 | Submission Open

Keywords: acute kidney injury in oncology; chronic kidney disease and cancer; paraneoplastic glomerulonephritis; immunotherapy-related nephrotoxicity; tumor lysis syndrome; nephrotoxicity of chemotherapeutic agents; DNA damage; epigenetic modifications; molecular pathways in cancer-associated kidney injury; biomarkers for early detection of kidney injury

(This special issue belongs to the Section Clinical Research of Cancer)

Novel Insight of MRI for Lung Cancer and Thoracic Neoplasm (2nd Edition)

edited by

Katsuo Usuda

submission deadline 18 Mar 2026 | Viewed by 208 | Submission Open

Keywords: oncologic imaging; cancer imaging; imaging of thoracic disease; magnetic resonance imaging (MRI); computed tomography (CT); positron emission tomography– computed tomography (PET-CT); diffusion-weighted magnetic resonance imaging (DWI); economic evaluation; imaging biomarkers

(This special issue belongs to the Section Methods and Technologies Development)

Targeted Therapy of Cholangiocarcinoma

edited by

Rosa Maria Pascale

submission deadline 19 Mar 2026 | Viewed by 143 | Submission Open

Keywords: cholangiocarcinoma; targeted therapy; molecular alterations; immunotherapy; precision medicine

(This special issue belongs to the Section Tumor Microenvironment)

Hematopoietic Stem Cell Transplant in Hematological Malignancies

edited by

Luisa Giaccone

and Alessandro Cignetti

submission deadline 20 Mar 2026 | 3 articles | Viewed by 7085 | Submission Open

Keywords: stem cell transplant; graft-versus-host disease; conditioning regimen; prophylaxes; immunology; donors; hematological disease

(This special issue belongs to the Section Cancer Therapy)

Drug Targeting Therapy in Multiple Myeloma

edited by

Hiroshi Handa

and

Hideto Tamura

submission deadline 20 Mar 2026 | 2 articles | Viewed by 6707 | Submission Open

Keywords: multiple myeloma; novel drug; novel targets; new therapeutic targets; prognosis

(This special issue belongs to the Section Cancer Drug Development)

Cancer Induced Organ Dysfunctions (Cachexia)

edited by

Sham S. Kakar

and Sarama Saha

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1437 | Submission Open

Keywords: cancer; cachexia; organ dysfunction; cancer-induced cachexia; cancer-induced organ dysfunction; muscle wasting

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Antibody–Drug Conjugates (ADCs) in Cancers

edited by

Jayanth Panyam

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1155 | Submission Open

Keywords: antibody– drug conjugates (ADCs); therapeutic efficacy; drug delivery; structural features; disposition; linker design; payload optimization

(This special issue belongs to the Section Cancer Drug Development)

Cervical Cancer Screening: Current Practices and Future Perspectives

edited by Kimon Chatzistamatiou

submission deadline 20 Mar 2026 | 1 articles | Viewed by 673 | Submission Open

Keywords: cervical cancer screening; cervical carcinogenesis; human papillomavirus; HPV primary screening; self-sampling; triage of HPV-positive; post-conization follow-up; screening for immunocompromised women; screening for vac-cinated women

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Cancer Survivors: Late Effects of Cancer Therapy

edited by

Gaurav Kumar

submission deadline 20 Mar 2026 | 1 articles | Viewed by 162 | Submission Open

Keywords: late effects; cancer survivorship; treatment toxicity; long-term outcomes

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Neuroendocrine Tumors: From Diagnosis to Therapy (2nd Edition)

edited by

Damiano Caruso

Francesco Panzuto

Michela Polici

and Daniela Prosperi

submission deadline 20 Mar 2026 | Viewed by 149 | Submission Open

Keywords: neuroendocrine neoplasms; CT; MR; PET/CT; target therapy; quantitative biomarkers

(This special issue belongs to the Section Cancer Therapy)

Artificial Intelligence in Ocular Oncology

edited by

Bertil E. Damato

submission deadline 20 Mar 2026 | Viewed by 120 | Submission Open

Keywords: ocular tumor; eye cancer; artificial intelligence; ophthalmology

(This special issue belongs to the Section Methods and Technologies Development)

Radiation Therapy in Lung Tumors: Recent Trends and Current Issues

edited by

Paul Jules van Houtte

and Sara Ramella

submission deadline 21 Mar 2026 | Viewed by 90 | Submission Open

Keywords: lung cancer; immunotherapy; chemotherapy; PET-CT; surgery; oligo-metastases

(This special issue belongs to the Section Cancer Therapy)

Bacterial Infections and Cancer Risk: From Biological Mechanisms to Clinical Realities

edited by

Skander Hathroubi

and Shuai Hu

submission deadline 25 Mar 2026 | 1 articles | Viewed by 1776 | Submission Open

Keywords: bacterial infections; cancer risk; biological mechanisms; treatment modalities; therapeutic strategies

(This special issue belongs to the Section Infectious Agents and Cancer)

Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies

edited by Ana Vidović

submission deadline 25 Mar 2026 | Viewed by 74 | Submission Open

Keywords: acute myeloblastic leukemia; diagnosis; prognosis; intensive chemotherapy; target therapy; allogeneic stem cell transplantation

(This special issue belongs to the Section Clinical Research of Cancer)

Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion

edited by

Agata Kabała-Dzik

submission deadline 28 Mar 2026 | Viewed by 155 | Submission Open

Keywords: urokinase-type plasminogen receptor; uPAR; inflammation; cancer; migration; invasion

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Pathology in Cancer: From Diagnosis to Precision Medicine

edited by

Georgia Levidou

submission deadline 28 Mar 2026 | Viewed by 28 | Submission Open

Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker

(This special issue belongs to the Section Cancer Pathophysiology)

Cancer Immunotherapy: Focus on Immune Checkpoint Inhibitors and Immune Modulators

edited by

Katsuaki Ieguchi

submission deadline 30 Mar 2026 | 4 articles | Viewed by 11543 | Submission Open

Keywords: PD-1; PD-L1; CTLA-4; immune checkpoint molecule; immune checkpoint inhibitor; tumor microenvironment; drug resistance; biomarker; BiTE; BiCE

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Quality and Clinical Outcomes Improvement in the Management of Oncology Patients (2nd Edition)

edited by

Dimitrios E. Magouliotis

submission deadline 30 Mar 2026 | 1 articles | Viewed by 1200 | Submission Open

Keywords: oncology; surgical oncology; quality improvement; clinical outcomes; patient safety

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Neoadjuvant Therapy for Pancreatic Cancer

edited by Brice Chanez

submission deadline 30 Mar 2026 | Viewed by 191 | Submission Open

Keywords: induction treatment; biomarkers; chemotherapy

(This special issue belongs to the Section Cancer Therapy)

Women’s Health and Gynaecological Cancers: From Nutrition and Environmental Factors to Novel Diagnostics and Therapies

edited by

and

submission deadline 31 Mar 2026 | 10 articles | Viewed by 31532 | Submission Open

Keywords: breast cancer; ovarian cancer; cervical cancer; endometrial cancer; nutrition; obesity; environmental factors; women's health; gynaecological cancers

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Recent Advances in Hepatobiliary Cancers: From Diagnosis to Treatment (2nd Edition)

edited by

Ilyas Sahin

submission deadline 31 Mar 2026 | 12 articles | Viewed by 28873 | Submission Open

Keywords: hepatobiliary cancers; hepatocellular carcinoma; cholangiocarcinoma; gallbladder cancer; immunotherapy; targeted therapy; precision medicine

(This special issue belongs to the Section Cancer Therapy)

Emerging Trends in Global Cancer Epidemiology: 2nd Edition

edited by Syed Ahsan Raza

submission deadline 31 Mar 2026 | 8 articles | Viewed by 28783 | Submission Open

Keywords: cancer epidemiology; global cancer research; incidence; prevention and control strategies; risk factors; data sources and methods; social and environmental impact; population health; emerging trends; survival and mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

PET/CT and Conventional Imaging in Cancers

edited by

Francesco Dondi

and

Domenico Albano

submission deadline 31 Mar 2026 | 7 articles | Viewed by 15469 | Submission Open

Keywords: PET/CT; CT; MR; conventional imaging; positron emission tomography; neoplasm; cancer

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Invasive Breast Cancer: Treatment and Prognosis (2nd Edition)

edited by

Eleni Timotheadou

and Emmanouil Saloustros

submission deadline 31 Mar 2026 | 7 articles | Viewed by 14351 | Submission Open

Keywords: ER+/HER2– breast cancer; HER2+ breast cancer; triple-negative breast cancer; treatment toxicity and quality of life; survivorship issues

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 401-450 on page 9 of 25.

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