Targeted Therapy of Cholangiocarcinoma

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: 19 March 2026 | Viewed by 30

Special Issue Editor


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Guest Editor
Department of Medical, Surgery and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, 07100 Sassari, Italy
Interests: molecular cancer biology; cancer biomarkers; cancer epidemiology and prevention; cancer pathophysiology; tumor microenvironment; cancer causes; screening and diagnosis; clinical trials of cancer; systematic review or meta-analysis in cancer research; methods and technologies development

Special Issue Information

Dear Colleagues,

We are pleased to announce the call for submissions to a Special Issue titled “Targeted Therapy of Cholangiocarcinoma”. Cholangiocarcinoma is a highly aggressive malignancy accounting for around 15% of primary liver cancers. Its silent development is often responsible for a diagnosis at an advanced stage. Recent knowledge has highlighted cholangiocarcinoma heterogeneity at the genomic and epigenetic molecular levels. Discovering molecular alteration(s) of cells of origin and their differentiation grade could pave the way for precision medicine approaches in cholangiocarcinoma management.

This Special Issue aims at providing a comprehensive overview of targeted therapies for cholangiocarcinoma, highlighting breakthroughs in molecular and genetic research, novel treatment strategies, and ongoing clinical trials. We invite submissions of original research articles and reviews that explore the following:

  1. Molecular and genetic alterations in cholangiocarcinoma;
  2. Novel targeted therapies and drug development;
  3. Biomarker-driven treatment approaches;
  4. The role of immunotherapy in cholangiocarcinoma;
  5. Combination therapies and emerging clinical trials.

All submitted articles will undergo rigorous peer review to ensure the highest scientific quality and relevance to the field. We encourage contributions from researchers, clinicians, and oncology experts to enhance the current understanding and treatment landscape of cholangiocarcinoma.

By consolidating the latest research findings and clinical experiences, we aim at advancing the development of personalized and effective treatment strategies. Your valuable contributions will play a crucial role in shaping the future of targeted therapy for cholangiocarcinoma.

Should you have any questions or require further information, please do not hesitate to contact us. We look forward to your submissions.

Prof. Rosa Pascale
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cholangiocarcinoma
  • targeted therapy
  • molecular alterations
  • immunotherapy
  • precision medicine

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Published Papers

This special issue is now open for submission.
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