Novel Approaches to the Management of Patients with Gastrointestinal Tumors
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 15 March 2026 | Viewed by 252
Special Issue Editors
Interests: gastrointestinal oncology; gastric cancer; colorectal cancer; pancreatic cancer; immunotherapy; clinical trials; neuroendocrine tumors
Special Issues, Collections and Topics in MDPI journals
Interests: gastrointestinal oncology; gastric cancer; colorectal cancer; immunotherapy; phase I clinical trials; neuroendocrine tumors; early drug development
Special Issue Information
Dear Colleagues,
Cancers of the digestive system are major contributors to global cancer-associated morbidity and mortality, accounting for 35% of cancer deaths annually. Although surgical resection remains the most common curative treatment for digestive cancers, the introduction of multimodal therapeutic approaches has improved the survival of many of these tumors. In addition, significant advancements in our understanding of the molecular biology underlying these tumors, including the interplay between cancer cells and the surrounding cancer microenvironment, have provided novel therapeutic alternatives and unprecedented insights into the genetic drivers of tumor progression, the mechanisms of therapy resistance, the role of targeted therapies, especially immunotherapy, and the key role of cfDNA in providing prognostic information. This knowledge is continuously translated into novel treatment concepts and targets, which are transforming the therapeutic landscape of these tumors. In this Special Issue, we will focus on novel approaches to the management of patients with esophageal, gastric, and colorectal cancers. This may include TNT approaches, the pharmacological management of these malignancies, including chemo-, targeted, and immunotherapy, innovative therapeutic strategies such as CAR-T cell therapy or novel antibody-drug conjugates, and the impact of artificial intelligence, the microbiome or omics on the design of alternative strategies.
Dr. Javier Rodríguez
Dr. Ignacio Matos García
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- clinical management
- gastric cancer
- colorectal cancer
- predictive factors
- novel therapies
- artificial intelligence
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