Neuroendocrine Tumors: From Diagnosis to Therapy (2nd Edition)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 26
Special Issue Editors
Interests: imaging; oncology; CT; MRI; artificial intelligence; radiomics; response to therapy
Special Issues, Collections and Topics in MDPI journals
2. Department of Medical, Surgical Sciences and Translational Medicine, Sapienza University of Rome, 00189 Rome, Italy
Interests: neuroendocrine tumors; gastrointestinal disorders; pancreatic diseases; malnutrition
Special Issues, Collections and Topics in MDPI journals
Interests: imaging; oncology; CT; MRI; artificial intelligence; radiomics; response to therapy
Special Issues, Collections and Topics in MDPI journals
Interests: nuclear medicine; PET/CT; response to therapy; PRRT
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our previous Special Issue titled “Neuroendocrine Tumors: From Diagnosis to Therapy” (https://www.mdpi.com/journal/cancers/special_issues/5BRW1F64W9).
Neuroendocrine neoplasms (NENs) are considered rare tumors with a wide spectrum of behaviors. Although they are mainly indolent, NENs are highly dependent on the presence of high-risk clinical features (such as metastatic disease, grading, ki67, the expression of somatostatin receptors, and primary sites). Diagnoses employ a dual morphological and functional approach in NENs and are based on histology and imaging.
However, these conventional evaluations present some intrinsic drawbacks, from limited tissue sampling in the case of tumor biopsy to bias linked to the subjective assessment of medical images. Furthermore, based on the assessment of response to therapy, the morphological RECIST 1.1 criteria may be reductive and inappropriate, especially in the case of target therapy.
In this context, quantitative imaging has acquired relevance as a supporting tool for clinicians in order to overcome the limits associated with the conventional approach, especially in prediction prognosis and in response to therapy. Thus, to outline a structured therapeutic path, one of the future landscapes of NEN management may be the integration of quantitative imaging with conventional evaluations.
This Special Issue will highlight the main strengths and limitations of the management of NENs, from diagnosis to response to therapy and will investigate the emerging role of quantitative biomarkers.
Dr. Damiano Caruso
Prof. Dr. Francesco Panzuto
Dr. Michela Polici
Dr. Daniela Prosperi
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- neuroendocrine neoplasms
- CT
- MR
- PET/CT
- target therapy
- quantitative biomarkers
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