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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Hematological Malignancies in Children

edited by

Radosław Chaber

submission deadline 30 Jun 2026 | 3 articles | Viewed by 7132 | Submission Open

Keywords: acute lymphoblastic leukemia; acute myeloid leukemia; hematological malignancies in children; diagnostic and therapeutic methods; supportive care strategies

(This special issue belongs to the Section Pediatric Oncology)

Clinical Research on Thoracic Cancer

edited by

Yuichi Saito

and

Hiroyuki Adachi

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6809 | Submission Open

Keywords: thoracic cancer; lung cancer; thymic cancer; malignant mesothelioma; radiotherapy; surgery; chemotherapy; immunotherapy; driver mutation

(This special issue belongs to the Section Clinical Research of Cancer)

Novel Diagnosis and Treatment Approaches in Pancreatic Cancer

edited by

Atsushi Masamune

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6539 | Submission Open

Keywords: pancreatic cancer; pancreatic fibrosis; biomarker; risk factor; genetic testing; artificial intelligence; endoscopic ultrasound; stroma; cancer-associated fibroblasts; familial pancreatic cancer

(This special issue belongs to the Section Cancer Therapy)

Natural Compounds in Cancers: 2nd Edition

edited by

Ivan Cruz-Chamorro

and

Guillermo Santos-Sánchez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 6166 | Submission Open

Keywords: nutrition; bioactive molecules; inflammation; natural extracts; nutraceuticals; immunotherapy; chemotherapy

(This special issue belongs to the Section Molecular Cancer Biology)

Advancements in the Diagnosis and Surgical Treatment of Prostate Cancer

edited by

Christian Peter Gilfrich

and Christian Thomas

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6092 | Submission Open

Keywords: robotic-assisted radical prostatectomy; significance of pelvic lymph node dissection in the context of radical prostatectomy; complications of surgical therapy for prostate cancer; magnetic resonance imaging/ultrasound-guided target biopsy of the prostate; comparison of various robotic systems for radical prostatectomy; learning curves; hospital volume; prostate cancer centers

(This special issue belongs to the Section Clinical Research of Cancer)

Exploring Immunotherapy in Colorectal Cancer

edited by

Alessandro Passardi

Luca Esposito

and

Chiara Gallio

submission deadline 30 Jun 2026 | 1 articles | Viewed by 5892 | Submission Open

Keywords: colorectal cancer; immunotherapy; immune checkpoint inhibitors; mismatch repair; microsatellite instability; biomarkers

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Pancreatic Cancer: Clinical Standards, Unmet Needs and Future Directions

edited by

Dimitrios H. Roukos

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5124 | Submission Open

Keywords: standard clinical management; surgery; neoadjuvant and/or adjuvant treatment; cancer immunotherapy; targeted therapy; detection and elimination of MRD

(This special issue belongs to the Section Clinical Research of Cancer)

Applications of Ex Vivo Microscopy in Cancer Detection and Diagnosis

edited by J. Quincy Brown

submission deadline 30 Jun 2026 | 4 articles | Viewed by 5059 | Submission Open

Keywords: microscopy; cancer; optical sectioning; diagnosis; detection

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Cancer Data and Statistics: 2nd Edition

edited by

Vesna Zadnik

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4814 | Submission Open

Keywords: cancer registries; cancer incidence; cancer survival; population-based studies; cancer risk factors

(This special issue belongs to the Section Cancer Informatics and Big Data)

Next-Generation Cancer Therapies

edited by

Achilleas Mitrakas

, Ioannis Lamprou and Erasmia Xanthopoulou

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4497 | Submission Open

Keywords: cancer; current therapies; cancer cells metabolism; autophagy; immunotherapy; targeted treatments; oncolytic viruses; vaccines

(This special issue belongs to the Section Cancer Therapy)

Sequence Variants in Breast/Ovarian Cancer Susceptibility Genes: From Risk Assessment to Clinical Management in Carrier Individuals and Their Blood Relatives

edited by Arcangela De Nicolo and

Miguel De la Hoya

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4463 | Submission Open

Keywords: breast/ovarian cancer susceptibility genes; risk assessment and clinical management of carrier individuals and their blood relatives; risk models; variant classification; multifactorial approaches

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Mechanosensing

edited by Meenal Datta and Xin Tang

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4277 | Submission Open

Keywords: cancer mechanosensing; mechanotransduction; mechanical cues; mechanosensitive ion channels; focal adhesions; cytoskeletal elements; tumor microenvironments; fluid shear stress; stiffness; cell compression; tumor progression; metastasis; drug resistance; immune response; biophysical tools

(This special issue belongs to the Section Cancer Pathophysiology)

Integrating Precision Medicine with Nanotechnology to Overcome Drug Resistance in Cancer

edited by Yan Li

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4241 | Submission Open

Keywords: precision medicine; nanotechnology; drug resistance

(This special issue belongs to the Section Methods and Technologies Development)

NK Cells in the Tumor Microenvironment: Immunosuppressive Mechanisms and Therapy

edited by

Alexander Barrow

and Julian Vivian

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4237 | Submission Open

Keywords: immunosuppression; activation; inhibition; receptor; NK-CAR; checkpoint; adoptive cell therapy; immunotherapy; tumor microenvironment; nanoparticles

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3848 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

(This special issue belongs to the Section Methods and Technologies Development)

Stereotactic Body Radiation and Stereotactic Ablative Radiotherapy Therapy for Cancers 2nd edition

edited by

Sam Beddar

and Michael D. Chuong

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3778 | Submission Open

Keywords: radiation therapy (oncology); stereotactic body radiation therapy (SBRT) and stereotactic ablative radiotherapy (SABR); ultra-hypofractionated and hypofractionated studies; ablative/dose-escalated studies; SBRT; SABR; and cyberknife technology; MRI guidance; tumor motion techniques and management; frame and frameless immobilization devices; SBRT/SABR dose constraints and toxicities; artificial intelligence/machine learning

(This special issue belongs to the Section Cancer Therapy)

Neurosurgical Advances in Brain Tumor Surgery

edited by Camilla Bonaudo, Alessandro Della Puppa and

Antonello Grippo

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3534 | Submission Open

Keywords: brain lesions/tumors; preoperative mapping; neuro-oncology; navigated TMS (n TMS); brain stimulation; optical imaging; cognitive mapping; awake surgery; functional mapping; functional preservation; intraoperative monitoring; neurophysiological monitoring

(This special issue belongs to the Section Clinical Research of Cancer)

Neuroscience of Brain Tumors

edited by Zefferino Rossini,

Miguel Segura Ginard

and Maria Pia Tropeano

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3427 | Submission Open

Keywords: neurosurgery; neuroscience; brain tumors (gliomas; meningiomas; and pituitary tumors); neural pathway; neuroimaging; neurogenetics

(This special issue belongs to the Section Molecular Cancer Biology)

Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition

edited by Claudio Spinelli and Marco Ghionzoli

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3379 | Submission Open

Keywords: thyroid nodule; thyroid cancer; guidelines; surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Fertility Preservation in Gynecological Cancer

edited by

Giuseppe Gullo

and

Luigi Della Corte

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3354 | Submission Open

Keywords: gynecological cancer; fertility preservation; surgery treatments; fertility sparing; psychological implication

(This special issue belongs to the Section Methods and Technologies Development)

Chemoprevention Advances in Cancer (2nd Edition)

edited by

Komal Raina

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3350 | Submission Open

Keywords: cancer prevention; chemoprevention; nutrition and cancer; bio-active food components; natural products; non-toxic anticancer agents; precision nutrition in cancer; tumor metabolomics; gut microbiome in cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice

edited by

Maria Trovato

, Silvia Martina Ferrari and

Fausto Famà

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3234 | Submission Open

Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities

(This special issue belongs to the Section Clinical Research of Cancer)

Molecular and Genetic Biomarkers in Oral Squamous Cell Carcinoma

edited by

Kalu U.E. Ogbureke

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3166 | Submission Open

Keywords: oral cancer; oropharyngeal cancer; biomarkers; liquid biopsy; genetic determinants

(This special issue belongs to the Section Cancer Biomarkers)

New Strategies for the Treatment of Melanoma and Non-Melanoma Skin Cancer

edited by

Yoshihide Asano

and

Taku Fujimura

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3104 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; immunotherapy; anti-PD-1 antibody; BRAF/MEK inhibitors; racial differences; prognosis

(This special issue belongs to the Section Cancer Therapy)

Technical and Technological Innovations in Head and Neck Cancer Surgery

edited by Marta Filauro

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2932 | Submission Open

Keywords: head and neck; squamous cell carcinoma; larynx; oral cavity; free flap; exoscope; TORS

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Neurofibromatosis

edited by Yunjia Chen and Yulong Fu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2909 | Submission Open

Keywords: neurofibromatosis; schwannomatosis; NF1; NF2; SMARCB1; LZTR1

(This special issue belongs to the Section Molecular Cancer Biology)

Innovations in Microsurgical Techniques for Breast Cancer Reconstruction

edited by

Babak J. Mehrara

and Robert J. Allen

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2827 | Submission Open

Keywords: breast reconstruction; autologous breast reconstruction; DIEP flap; robotic DIEP flap; sensibility; alternative flaps; post-mastectomy pain; PAP flap; LAP flap; GAP flap; LTP flap; perforator flap; latissimus flap; fat grafting; nerve repair

(This special issue belongs to the Section Methods and Technologies Development)

Radioimmunotherapy, Neoadjuvant Immunotherapy, and Adjuvant Immunotherapy for Cancer

edited by

Rashidul Alam Mahumud

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2594 | Submission Open

Keywords: immunotherapy; radioimmunotherapy; neoadjuvant immunothearpy; radiopharmaceuticals

(This special issue belongs to the Section Cancer Therapy)

Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention

edited by Adam Barsouk

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2487 | Submission Open

Keywords: epidemiology; disparities; oncology; cancer; prevention

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2393 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Molecular Pathology and Human Cancers

edited by Stefano Marletta, Alessandro Russo and Giuliana Pavone

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2314 | Submission Open

Keywords: molecular pathology; cancer pathogenesis; targeted therapy; personalized medicine; cancer signaling

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Breast Cancer Imaging: From Detection to Personalized Diagnosis

edited by

Nuno Matela

and

Ana Margarida Mota

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2207 | Submission Open

Keywords: breast cancer imaging; artificial intelligence; radiomics; deep learning; personalized diagnosis; multimodal imaging; predictive modeling; early detection; treatment response; clinical applications

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Challenges and New Developments in the Diagnosis and Treatment of Sarcoma

edited by

Xiaolan Feng

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1988 | Submission Open

Keywords: bone and soft tissue sarcoma; prognostic and predictive biomarker; transcriptomic/genomic profiling; immunotherapy; targeted treatment

(This special issue belongs to the Section Cancer Therapy)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1960 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Plasma and Cancer Treatment

edited by

Michael Keidar

and

Vikas Soni

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1934 | Submission Open

Keywords: cold atmospheric plasma (CAP); cancer treatment; plasma medicine; reactive oxygen species (ROS); apoptosis; tumor; non-thermal plasma; plasma oncology; cancer and molecular biology; clinical translation; in vivo/preclinical

(This special issue belongs to the Section Cancer Therapy)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1664 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1459 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1447 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Surgery in Metastatic Cancer (2nd Edition)

edited by

Ulrich Ronellenfitsch

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1422 | Submission Open

Keywords: metastatic cancer; surgery; metastasectomy; indication; timing

(This special issue belongs to the Section Cancer Therapy)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1274 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition)

edited by

Daochun Sun

and

Sameer Farouk Sait

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1259 | Submission Open

Keywords: NF1; tumorigenesis; cancer stem cells; targeted therapy; tumor microenvironment; epigenetics; case report; metastasis; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Recent Advances in Epidemiology of Childhood Cancer

edited by Rafael Peris-Bonet,

Rebeca Ramis

and Adela Cañete

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1254 | Submission Open

Keywords: childhood cancer epidemiology; childhood cancer registries; environmental causes of childhood cancer; genetic epidemiology; molecular epidemiology; survival of children with cancer; quality of life; social determinants and inequalities; information technologies and statistical innovations

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1207 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Understanding the Molecular Basis and Immunobiology of Renal Cell Carcinoma and Exploring Novel Therapeutic Strategies

edited by

Heba Khella

submission deadline 30 Jun 2026 | 1 articles | Viewed by 925 | Submission Open

Keywords: renal cell carcinoma; molecular basis; immunobiology; tumor microenvironment; immunotherapy; targeted therapy; metastasis; precision medicine; biomarkers; non-coding RNA; miRNA; prognosis; molecular diagnostics; translational research

(This special issue belongs to the Section Cancer Therapy)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Jun 2026 | 1 articles | Viewed by 895 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Advances in Pancreatic Cancer: Exploring Biomarkers and Prognostic Predictors

edited by

Makoto Abue

submission deadline 30 Jun 2026 | 1 articles | Viewed by 785 | Submission Open

Keywords: pancreatic cancer; biomarkers; diagnosis; prognosis; liquid biopsy; proteomics; metabolomics; tumor microenvironment; genetic aberrations/mutations; inflammatory markers

(This special issue belongs to the Section Cancer Biomarkers)

Non-Coding RNAs and Extracellular Vesicles in Cancer Crosstalk: Diagnostic and Therapeutic Implications 2nd Edition

edited by

Simona Taverna

and

Giuseppe Cammarata

submission deadline 30 Jun 2026 | 1 articles | Viewed by 762 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; inflammation; non-coding RNA; microRNAs; circular-RNAs; PIWI-RNAs; lnc-RNAs

(This special issue belongs to the Section Cancer Therapy)

Pleural Mesothelioma: From Diagnosis to Treatment

edited by

Giovanni Luca Ceresoli

and

Paolo Andrea Zucali

submission deadline 30 Jun 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: pleural mesothelioma; histological classification; molecular characteristics; immunotherapy; chemotherapy; radiotherapy; surgery; targeted therapy; emerging therapies

(This special issue belongs to the Section Cancer Therapy)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 30 Jun 2026 | 1 articles | Viewed by 597 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 30 Jun 2026 | 1 articles | Viewed by 576 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 751-800 on page 16 of 25.

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