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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research Advances and Therapeutic Strategies (RATS) in Cardio-Oncology submission deadline 1 May 2026 | 2 articles | Viewed by 4072 | Submission Open
Keywords: cardiotoxicity; artificial intelligence; multi-omics; cardiac toxicities; surveillance; cardioprotective agents; multimodal imaging
(This special issue belongs to the Section Cancer Therapy)
Urologic Cancer: Endoscopic, Laparoscopic, and Robot-Assisted Surgery Management (2nd Edition)
edited by Kouji Izumi
submission deadline 1 May 2026 | 1 articles | Viewed by 3292 | Submission Open
Keywords: prostate cancer; urothelial cancer; kidney cancer; adrenal cancer; transurethral technique; ureteroscopy; ureteral stent
(This special issue belongs to the Section Cancer Therapy)
Protein Kinases and Signal Transduction Pathways in Regulating Tumor Growth
edited by
submission deadline 1 May 2026 | 1 articles | Viewed by 986 | Submission Open
Keywords: protein kinases; protein kinase inhibitors; protein phosphatases; inositol kinases; signal integration; kinase– lipid interaction
(This special issue belongs to the Section Cancer Biomarkers)
Advances of Particle Therapy in Prostate Cancer—2nd Edition
edited by
submission deadline 7 May 2026 | Viewed by 315 | Submission Open
Keywords: prostate cancer; particle therapy; radiation therapy; diagnosis; treatment; SBRT; IMRT
(This special issue belongs to the Section Cancer Therapy)
Rehabilitation Opportunities in Cancer Survivorship
edited by and Alejandro Heredia-Ciuro
submission deadline 8 May 2026 | 3 articles | Viewed by 6880 | Submission Open
Keywords: cancer; rehabilitation; sequelae; disability; impairment
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Artificial Intelligence for Cancer Precision Medicine
edited by Chenyang Shen and
submission deadline 8 May 2026 | Viewed by 84 | Submission Open
Keywords: artificial intelligence; cancer; radiomics
(This special issue belongs to the Section Methods and Technologies Development)
Epigenetics in Cancer and Drug Therapeutics
edited by Bethsebie Sailo and Anup R. Sharma
submission deadline 10 May 2026 | 1 articles | Viewed by 2688 | Submission Open
Keywords: cancer epigenetics; chromatin remodeling complexes; histone modifiers; DNA methylation; molecular target; cancer therapy
(This special issue belongs to the Section Molecular Cancer Biology)
Hepatocellular Carcinoma Progression and Metastasis
edited by
submission deadline 10 May 2026 | 1 articles | Viewed by 2265 | Submission Open
Keywords: hepatocellular carcinoma; tumor progression; metastasis; liver cancer; angiogenesis; epithelial– mesenchymal transition; tumor microenvironment; molecular pathways; biomarkers; targeted therapy; systemic therapy
(This special issue belongs to the Section Cancer Metastasis)
Artificial Intelligence for Network-Based Oncomarker Discovery and Cancer Prediction
edited by Oleg Blyuss
submission deadline 10 May 2026 | 3 articles | Viewed by 2180 | Submission Open
Keywords: artificial intelligence (AI); network-based biomarkers; graph neural networks (GNNs); multi-omic integration; cancer prediction; oncomarker discovery; prognostic and predictive biomarkers
(This special issue belongs to the Section Cancer Informatics and Big Data)
Genetics in Hematological Malignancies
edited by
submission deadline 10 May 2026 | 1 articles | Viewed by 1804 | Submission Open
Keywords: hematological malignancies; genomic alterations; personalized medicine; next-generation sequencing; epigenetics; biomarkers; leukemia; lymphoma; myeloma; genetic profiling
(This special issue belongs to the Section Molecular Cancer Biology)
Targeted Therapy of Pediatric Cancer (2nd Edition) submission deadline 10 May 2026 | 1 articles | Viewed by 1368 | Submission Open
Keywords: leukemia; lymphoma; pediatric solid malignancies; targeted therapy; biomarker discovery; actionable mutations; drug vulnerabilities; combination therapy; immunotherapeutic approaches; preclinical studies
(This special issue belongs to the Section Pediatric Oncology)
Oncoproteins in Cancers: Transcriptional Regulation, Signaling and Targeted Therapy submission deadline 11 May 2026 | Viewed by 226 | Submission Open
Keywords: oncoproteins; targeted therapy; oncogenic signaling pathways; tumor microenvironment; oxidative stress and cancer; tumorigenesis; cancer chemoprevention
(This special issue belongs to the Section Molecular Cancer Biology)
Molecular and Clinical Challenges in Metastatic and Oligometastatic Genitourinary Cancers
edited by Marlon Perera
submission deadline 11 May 2026 | Viewed by 48 | Submission Open
Keywords: genitourinary cancers; oligometastatic disease; metastasis-directed therapy; precision oncology; molecular profiling; biomarkers; liquid biopsy; tumour microenvironment; imaging and radiomics
(This special issue belongs to the Section Cancer Metastasis)
Systemic Treatment for Breast Cancer submission deadline 12 May 2026 | Viewed by 43 | Submission Open
Keywords: breast cancer; biomarker; treatment; management
(This special issue belongs to the Section Cancer Therapy)
Immune-Related Adverse Events in Cancer Immunotherapy
edited by Kate Young and Anna Olsson-Brown
submission deadline 15 May 2026 | 6 articles | Viewed by 16711 | Submission Open
Keywords: check point inhibitors (CPIs); immunotherapy; irAEs; immune checkpoint inhibitors (ICIs); survivorship; long-term toxicity; steroid refractory; biologics; CAR-T; TILs
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Infectious Agents and Cancer in Children and Adolescents
edited by and Eleni Tsotridou
submission deadline 15 May 2026 | 4 articles | Viewed by 11989 | Submission Open
Keywords: infectious agents; immune system; tumor development; immunological memory; oncolytic viruses
(This special issue belongs to the Section Infectious Agents and Cancer)
Endoscopic Advances in Gastrointestinal Oncology
edited by Eduardo Rodrigues-Pinto
submission deadline 15 May 2026 | 1 articles | Viewed by 5815 | Submission Open
Keywords: endoscopic oncology; endoscopic screening; endoscopic resection; endoscopic palliation; staging
(This special issue belongs to the Section Cancer Therapy)
Recent Advance in Colorectal Cancer Liver Metastases
edited by and Jennifer Kalil
submission deadline 15 May 2026 | 3 articles | Viewed by 5462 | Submission Open
Keywords: colorectal cancer liver metastases; histological growth patterns; chemotherapy optimization; liver regeneration; future liver remnant; liquid biopsy; treatment resistance
(This special issue belongs to the Section Cancer Metastasis)
Surgical Management of Non-Small Cell Lung Cancer
edited by József Furák
submission deadline 15 May 2026 | 4 articles | Viewed by 4227 | Submission Open
Keywords: non-small cell lung cancer; surgery; treatment; segmentectomy
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer Screening: Global Practices and Future Directions
edited by Rudolf Morant
submission deadline 15 May 2026 | 2 articles | Viewed by 2141 | Submission Open
Keywords: mammography screening; organized screening programs; tomosynthesis; 2D mammography; artificial intelligence; personalized screening
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Recent Advances in Trachea, Bronchus and Lung Cancer Management: 2nd Edition
edited by , Dionisios G. Spyratos and
submission deadline 15 May 2026 | 1 articles | Viewed by 1164 | Submission Open
Keywords: trachea; bronchus and lung cancer; non-small cell lung cancer (NSCLC); small cell lung cancer (SCLC); cancer management; clinical suspicion; diagnosis; treatment; prevention
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Integrative Histopathological–Molecular–Computational Analysis of Primary Brain Tumors
edited by
submission deadline 15 May 2026 | Viewed by 586 | Submission Open
Keywords: brain tumor histopathology; neuropathology; molecular pathology; digital pathology; artificial intelligence; bioinformatics; computational pathology; deep learning
(This special issue belongs to the Section Cancer Informatics and Big Data)
Minimally Invasive Gastric Cancer Surgery
edited by , Simone Giacopuzzi and Felix Berlth
submission deadline 15 May 2026 | Viewed by 392 | Submission Open
Keywords: gastric cancer; laparoscopy; robotic surgery; fluorescence; minimally invasive surgery; lymphadenectomy
(This special issue belongs to the Section Cancer Therapy)
Molecular and Genetic Diagnosis and Targeted Therapy of Myeloproliferative Neoplasms (2nd Edition)
edited by and
submission deadline 15 May 2026 | 1 articles | Viewed by 323 | Submission Open
Keywords: myeloproliferative neoplasm; chronic myeloid leukemia; polycythemia vera; essential thrombocythemia; primary myelofibrosis; MPN; CML; PMF; PV; ET
(This special issue belongs to the Section Molecular Cancer Biology)
Targeted Therapy for Liver Metastases submission deadline 15 May 2026 | Viewed by 310 | Submission Open
Keywords: targeted therapy; liver metastases; biological therapy
(This special issue belongs to the Section Cancer Therapy)
Gene Editing and Delivery for Cancer Therapy (2nd Edition)
edited by and
submission deadline 15 May 2026 | Viewed by 175 | Submission Open
Keywords: gene therapy; gene editing; gene delivery; oncolytic viruses; nanomaterial; peptides; nanostructures; exosomes; translational science
(This special issue belongs to the Section Cancer Therapy)
Mass Spectrometry and Cancers submission deadline 15 May 2026 | Viewed by 136 | Submission Open
Keywords: cancer; biomolecular; mass spectrometry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Locoregional Therapies for Gastrointestinal Cancer Metastases submission deadline 15 May 2026 | Viewed by 105 | Submission Open
Keywords: gastrointestinal cancer metastases; locoregional therapies; interventional radiology; endoscopy; radiation therapy; invasive operations; cytoreductive surgery (CRS); intraperitoneal chemotherapy (IP); heated intraperitoneal chemotherapy (HIPEC); tumor debulking; stereotactic body radiation therapy (SBRT); selective internal radiation therapy (SIRT)
(This special issue belongs to the Section Methods and Technologies Development)
The Surgical Management of Colorectal Cancer
edited by Gyung-mo Son
submission deadline 20 May 2026 | 10 articles | Viewed by 27762 | Submission Open
Keywords: colorectal cancer; surgical management; minimally invasive surgery; laparoscopic surgery; robotic surgery; single port surgery; emergency surgery; image-guided surgery; enhanced recovery after surgery (ERAS); systemic metastasis in colorectal cancer (involving the liver; lung; peritoneum; etc.)
(This special issue belongs to the Section Cancer Therapy)
New Advances in the Treatment of Pediatric Solid Tumors
edited by and Oz Mordechai
submission deadline 20 May 2026 | 3 articles | Viewed by 9025 | Submission Open
Keywords: pediatric oncology; solid tumors; precision medicine; immunotherapy; artificial intelligence; innovative therapies
(This special issue belongs to the Section Pediatric Oncology)
Improving the Quality of Life in Patients with Gynecological Cancer
edited by Vasilios Pergialiotis
submission deadline 20 May 2026 | 2 articles | Viewed by 6147 | Submission Open
Keywords: gynecologic oncology; minimal invasive surgery; ovarian cancer; ERAS protocol; perioperative care; immunonutrition; cervical cancer
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
From Bench to Bedside: Novel Molecular Targets and Therapeutic Strategies in AML
edited by Matteo Molica
submission deadline 20 May 2026 | 2 articles | Viewed by 2760 | Submission Open
Keywords: acute myeloid leukemia; targeted therapy; precision medicine; FLT3 inhibitors; IDH1/2 inhibitors; BCL2 inhibition; menin inhibitors; drug resistance; minimal residual disease; combination therapy
(This special issue belongs to the Section Cancer Therapy)
How to Properly Diagnose and Treat Immune-Related Adverse Events During Immunotherapy in Patients with Cancer: Discussion Between Specialists (2nd Edition) submission deadline 20 May 2026 | Viewed by 115 | Submission Open
Keywords: ICIs; immune-related adverse effects (irAEs); infectious complications; immune reconstitution; inflammatory syndrome (IRIS); microbiota; vaccines; molecular mimicry
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in Endometrial Cancer Prevention, Early Diagnosis and Treatment
edited by
submission deadline 20 May 2026 | Viewed by 108 | Submission Open
Keywords: endometrial cancer; gynaecologic oncology; surgery; prevention; early diagnosis; advanced therapy; molecular classification; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Advances in T-Cell Redirecting Therapy in Plasma Cell Neoplasms
edited by Henry Chi Hang Fung and Asya Varshavsky
submission deadline 20 May 2026 | Viewed by 105 | Submission Open
Keywords: multiple myeloma; CAR-T; T-cell engager; novel targets; sequencing
(This special issue belongs to the Section Cancer Therapy)
Viral Oncogenes and Their Role in Cancer Pathogenesis
edited by and Yosef Sabo
submission deadline 21 May 2026 | 3 articles | Viewed by 7622 | Submission Open
Keywords: viral oncogenes; cancer pathogenesis; cellular regulation; tumorigenesis mechanisms; antiviral and anticancer strategies
(This special issue belongs to the Section Infectious Agents and Cancer)
Non-Melanoma Skin Cancer: A Growing Problem in the Elderly Population
edited by Jolanta Jaworek and Dariusz Kowalczyk
submission deadline 21 May 2026 | Viewed by 53 | Submission Open
Keywords: NMSC; pathomechanism of NMSC; NMSC and gut and/or skin microbiota; NMSC treatment; NMSC diagnosis
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Next-Generation Automation in Radiation Oncology: Innovations in Planning, Informatics, and Clinical Workflow
edited by and Jared Becksfort
submission deadline 22 May 2026 | Viewed by 65 | Submission Open
Keywords: radiation oncology; radiotherapy automation; autosegmentation; rapid automated treatment planning; zero-click quality assurance; fast clinical workflow; artificial intelligence; machine learning; clinical decision support; radiomics; image-guided radiotherapy; adaptive radiation therapy; human-in-the-loop automation; healthcare informatics
(This special issue belongs to the Section Methods and Technologies Development)
Inhibitors in Thyroid Carcinoma (2nd Edition) submission deadline 24 May 2026 | Viewed by 151 | Submission Open
Keywords: thyroid carcinoma; immune checkpoint inhibitors; tyrosine kinase inhibitors; sorafenib; lenvatinib
(This special issue belongs to the Section Tumor Microenvironment)
Study on Acute Myeloid Leukemia
edited by Olga K. Weinberg
submission deadline 25 May 2026 | 3 articles | Viewed by 7259 | Submission Open
Keywords: acute myeloid leukemia (AML); cancer treatment; genetic
(This special issue belongs to the Section Cancer Therapy)
Advances in Molecular Mechanisms of Gastrointestinal Tumors (2nd Edition)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 5420 | Submission Open
Keywords: molecular mechanism; gastrointestinal tumor; gastric cancer; colorectal cancer; esophageal cancer; tumor microenvironment; molecular network; molecular pathway; pathway network; signal transduction
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical Advances and State-of-the-Art Management in Genitourinary Cancers
edited by and Adnan Fazili
submission deadline 25 May 2026 | 2 articles | Viewed by 5346 | Submission Open
Keywords: genitourinary malignancies; tumor– immune microenvironment (TIME); tumor biology; genomic characterization; targeted drug therapy; immunotherapy
(This special issue belongs to the Section Clinical Research of Cancer)
Colorectal Cancer: Risk Factors and Underlying Mechanisms
edited by David Achaintre
submission deadline 25 May 2026 | 1 articles | Viewed by 1099 | Submission Open
Keywords: colorectal cancer; diet; environmental factors; microbiome; inflammation
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Digital Health Technologies in Oncology: 2nd Edition submission deadline 25 May 2026 | Viewed by 192 | Submission Open
Keywords: digital healthcare; digital health technologies; diagnosis; wearable devices; rehabilitation technologies; assistive technologies; robotic surgery; (remote) monitoring; precision medicine; data analytics; healthcare teleassistance; AI-driven diagnostics and monitoring; AI-driven analytics.
(This special issue belongs to the Section Methods and Technologies Development)
Molecular Mechanisms of Breast Cancer Treatment-Related Side Effects and Precision Interventions
edited by
submission deadline 26 May 2026 | Viewed by 130 | Submission Open
Keywords: breast cancer; treatment-related side effects; biomarker; precision interventions
(This special issue belongs to the Section Cancer Therapy)
Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies
edited by Nithya Ratnavelu and Ioannis Biliatis
submission deadline 28 May 2026 | 4 articles | Viewed by 7336 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
New Approaches in Radiotherapy for Cancer
edited by Dandan Zheng, Alexander Podgorsak and Olga Maria Dona Lemus
submission deadline 30 May 2026 | 21 articles | Viewed by 87105 | Submission Open
Keywords: adaptive radiotherapy; FLASH; artificial intelligence; SFRT; particle therapy; proton therapy; SRS; SBRT; HDR; 3D printing; immuno-radiotherapy; radiogenmics
(This special issue belongs to the Section Cancer Therapy)
Advances in the Surgical Treatment of Spinal Tumors
edited by Daniel Lubelski
submission deadline 30 May 2026 | 4 articles | Viewed by 4954 | Submission Open
Keywords: spinal tumors; spinal metastases; minimally invasive spine surgery; radiosurgery; histology-specific treatment; prognostic modeling; machine learning; deep learning; spinal reconstruction; quality of life
(This special issue belongs to the Section Cancer Therapy)
AI-Driven Oncology: Advancing Cancer Detection, Diagnosis, and Personalized Treatment submission deadline 30 May 2026 | 4 articles | Viewed by 4483 | Submission Open
Keywords: cancer detection and diagnosis; AI in oncology; explainable AI (XAI); precision oncology; medical imaging; prognostic biomarkers; clinical decision support systems
(This special issue belongs to the Section Methods and Technologies Development)
Endoscopic Management of Pancreatic Neoplasms (2nd Edition)
edited by
submission deadline 30 May 2026 | 2 articles | Viewed by 4365 | Submission Open
Keywords: pancreatic cancer; pancreatic neoplasm; endoscopic retrograde cholangiopancreatography; endoscopic ultrasound; fine needle aspiration/biopsy; local treatment; biliary stent; biliary drainage; contrast enhancement
(This special issue belongs to the Section Methods and Technologies Development)
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