Endoscopic Advances in Gastrointestinal Oncology

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 1543

Special Issue Editor


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Guest Editor
Gastroenterology Department, Centro Hospitalar Universitário de São João, Porto, Portugal
Interests: therapeutic endoscopy; endoscopic treatment of benign and malignant strictures, leaks and fistulas; endoscopic retrograde cholangiopancreatography; endoscopic mucosal resection

Special Issue Information

Dear Colleagues,

Endoscopy has provided physicians with unprecedented access to the gastrointestinal tract, with implications for the management of all major oncological diseases in the gastrointestinal tract. With rapid advances in endoscopic technology, endoscopists are assuming an increasingly significant role in endoscopic oncology. The application of endoscopy affects many aspects of cancer management, ranging from the diagnosis of premalignant and malignant conditions to surveillance of premalignant conditions, the staging of cancers, definitive therapy for early-stage neoplasms, and palliation.

This Special Issue is devoted to the current and future role of the endoscopic oncologist, with a focus on the latest endoscopic advances in the diagnosis, management, and treatment of premalignant and malignant gastrointestinal conditions.

Prof. Dr. Eduardo Rodrigues-Pinto
Guest Editor

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Keywords

  • endoscopic oncology
  • endoscopic screening
  • endoscopic resection
  • endoscopic palliation
  • staging

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Published Papers (1 paper)

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Review

14 pages, 583 KiB  
Review
Self-Expandable Metal Stents for Obstructing Colon Cancer and Extracolonic Cancer: A Review of Latest Evidence
by Pedro Marílio Cardoso and Eduardo Rodrigues-Pinto
Cancers 2025, 17(1), 87; https://doi.org/10.3390/cancers17010087 - 30 Dec 2024
Cited by 1 | Viewed by 1153
Abstract
Colorectal cancer (CRC) is a leading cause of cancer mortality, with many patients presenting with malignant colorectal obstruction (MCO). Self-expandable metal stents (SEMSs) have emerged as a minimally invasive key intervention, both as a bridge to surgery (BTS) in curative setting sand for [...] Read more.
Colorectal cancer (CRC) is a leading cause of cancer mortality, with many patients presenting with malignant colorectal obstruction (MCO). Self-expandable metal stents (SEMSs) have emerged as a minimally invasive key intervention, both as a bridge to surgery (BTS) in curative setting sand for palliation in advanced disease. This review aims to provide an evidence-based analysis of SEMS indications, contraindications, and efficacy across curative and palliative contexts, with focus on long-term outcomes. Based on data from recent trials and guidelines, we examine SEMS placement outcomes, focusing on specific scenarios, including BTS for left-sided MCO, chemotherapy (with angiogenic agents) safety during stent therapy, the optimal timing between SEMS placement and surgery, and oncological outcomes. We also discuss the use of SEMSs in challenging contexts such as proximal colon obstruction and extracolonic obstruction, and the relevant technical considerations. Findings indicate that using a SEMS in the BTS setting reduces emergency surgery needs, minimizes complications, and decreases stoma formation. Long-term oncologic outcomes, particularly recurrence, are still debated, but recent evidence shows that SEMS placement is safe, without worsening long term outcomes. Palliative SEMS placement shows high efficacy in symptom relief with manageable adverse events. Success depends on patient selection and technical expertise, with multidisciplinary approaches essential for optimal outcomes. Full article
(This article belongs to the Special Issue Endoscopic Advances in Gastrointestinal Oncology)
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