Artificial Intelligence for Network-Based Oncomarker Discovery and Cancer Prediction

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Informatics and Big Data".

Deadline for manuscript submissions: 10 May 2026 | Viewed by 38

Special Issue Editor


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Guest Editor
Wolfson Institute of Population Health, Queen Mary University of London, London, UK
Interests: machine learning; medical statistics; artificial intelligence; longitudinal data; early detection; active surveillance

Special Issue Information

Dear Colleagues,

The discovery of reliable biomarkers, or oncomarkers, remains one of the central challenges in oncology, with profound implications for early detection, prognosis, and personalised treatment strategies. While traditional biomarker studies have provided important insights, they often focus on individual molecules rather than the complex biological networks driving cancer initiation and progression.

Recent advances in artificial intelligence (AI) and machine learning (ML) are enabling a paradigm shift toward network-based biomarker discovery. By integrating genomics, transcriptomics, proteomics, epigenomics, and metabolomics, AI methods can uncover novel molecular interactions, dysregulated pathways, and predictive signatures that may remain hidden in conventional analyses. In particular, graph neural networks (GNNs), network embeddings, and systems biology-inspired approaches hold promise for identifying prognostic and predictive oncomarkers, improving risk stratification, and informing clinical decision support in oncology.

The aim of this Special Issue is to bring together cutting-edge research and comprehensive reviews on the applications of AI for network-based biomarker discovery and cancer prediction. We welcome contributions that explore computational innovations and translational insights with clinical relevance.

Dr. Oleg Blyuss
Guest Editor

Manuscript Submission Information

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Keywords

  • artificial intelligence (AI)
  • network-based biomarkers
  • graph neural networks (GNNs)
  • multi-omic integration
  • cancer prediction
  • oncomarker discovery
  • prognostic and predictive biomarkers

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Published Papers

This special issue is now open for submission.
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