Infectious Agents and Cancer in Children and Adolescents
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Infectious Agents and Cancer".
Deadline for manuscript submissions: 15 May 2025 | Viewed by 62
Special Issue Editors
Interests: childhood cancer; survivorship; adolescents and young adults with cancer; acute lymphoblastic leukemia; Hodgkin lymphoma; thrombosis
Special Issues, Collections and Topics in MDPI journals
Interests: miRNAs; epigenetics; acute lymphoblastic leukemia; immunooncology
Special Issue Information
Dear Colleagues,
The complex interplay between infectious agents, the immune system and tumor development, progression and clearance has been drawing increasing attention. Pathogens share common antigenic epitopes with neoplastic cells; as such, the hypothesis that prior infection aids the clearance of neoplastic cells by creating immunological memory has been developed. On the other hand, there is accumulating evidence for the possible involvement of infectious agents in the pathogenesis of a variety of malignancies. The established oncogenic viruses represent only the tip of the iceberg. Prior infection affects the immunological status, i.e., Th1 versus Th2 polarization, and hence the success of immunosurveillance. Chronic low-grade inflammation associated with infections has also been linked with an increased risk of tumorigenesis. Recently, infectious agents in the form of oncolytic viruses have revolutionized the field of oncology by either selectively infecting and lysing neoplastic cells or modifying the tumor microenvironment. Finally, infections represent a major cause of morbidity and mortality among cancer patients, especially nowadays that the intensity of chemotherapy has been pushed to the limit of tolerance in several neoplasms.
This Special Issue aims to showcase original research articles, along with state-of-the-art reviews on the broad spectrum of the role of infectious agents in cancer pathogenesis and treatment, as well as in the form of malignancy-related or treatment-related complications.
Dr. Emmanouel Hatzipantelis
Dr. Eleni Tsotridou
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- infectious agents
- immune system
- tumor development
- immunological memory
- oncolytic viruses
