Targeted Therapy for Liver Metastases
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 1 November 2025 | Viewed by 138
Special Issue Editors
Interests: surgical oncology; liver cancers; pancreatic cancers; biliary cancers; liver surgery; pancreatic surgery; biliary surgery; minimally invasive surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The unique vascular and anatomical structures of the liver create a favorable environment for metastatic cancer engraftment and survival, making secondary tumors the most frequently observed liver malignancies. Liver metastases are most commonly originating from colorectal cancer or generally the gastrointestinal tract, but almost half of patients affected by different cancer types will present with or eventually develop liver metastases. The liver oncological status is often a key determinant of patient prognosis, and the possibility of predicting, early diagnosing, and effectively treating liver metastases can significantly prolong survival.
The management is often challenging and should be coordinated by a multidisciplinary team involving oncologists, surgeons, radiologists, radiotherapists, pathologists, and specialized nurses in order to select the best possible treatment among the various therapeutic options with a personalized, patient-centered approach.
In recent decades, thanks to the increased knowledge of tumor and microenvironment biology and molecular profiles, targeted therapies have been developed and integrated into cancer treatment.
This Special Issue will highlight all the possible roles of targeted therapy for liver metastases in all their diversity, covering all aspects that advance our understanding of such a complex oncological entity.
Dr. Gianluca Rompianesi
Dr. Jacopo Lanari
Guest Editors
Manuscript Submission Information
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Keywords
- targeted therapy
- liver metastases
- biological therapy
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