Tumor Microenvironment
A section of Cancers (ISSN 2072-6694).
Section Information
The MDPI journal Cancers has recently defined the scope and have introduced a Tumor Microenvironment Section. The TME section aims to publish high-quality research on the molecular and cellular components of cancer microenvironment, with a particular focus on basic, translational and clinical research that has significant implications for the diagnosis, prevention and treatment of human malignancies. The subject area include, but not limited to, the mechanisms playing essential role in tumor cell plasticity under the influence of unique microenvironment, molecular and cellular markers for diagnosis, prognosis, drug targets in malignant cells and its microenvironment, and the role of microbiome in influencing the etiology and characteristics of cancer cell. The section also encourages communication of scientific advancement in complementary and alternative medicines influencing tumor microenvironment.
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Targeted Therapy of Cholangiocarcinoma (Deadline: 19 March 2026)
- TGF-β Signaling in the Tumor Microenvironment: Dual Roles in Cancer Progression and Therapy (Deadline: 31 March 2026)
- Genetic Alterations and the Tumor Microenvironment (Deadline: 31 March 2026)
- Mastering the Immunosuppressive Tumor Microenvironment with Cancer Vaccines (Deadline: 31 March 2026)
- Cancer Cell Motility (2nd Edition) (Deadline: 2 April 2026)
- Endothelial Cells in Inflammation, Tissue Repair, Ageing and Cancer: 2nd Edition (Deadline: 10 April 2026)
- The Bone Marrow Microenvironment in Myelodysplastic Syndromes—Pathogenesis, Immune Evasion, and Therapeutic Opportunities (Deadline: 15 April 2026)
- Advances in Cellular Heterogeneity and Plasticity in the Tumor Microenvironment (Deadline: 15 April 2026)
- The Influence of Epigenetic Regulation on the Tumor Microenvironment: Mechanisms and Therapeutic Implications (Deadline: 30 April 2026)
- Myeloma: Pathogenesis and Targeted Therapies (Deadline: 30 April 2026)
- Fatty Acid Synthesis and Mitochondrial Beta-Oxidation in Cancer (Deadline: 30 April 2026)
- G Protein-Coupled Receptors in Cancer Progression (Deadline: 30 April 2026)
- Role of Myeloid Cells in the Regulation of Cancer Onset and Development (Deadline: 30 April 2026)
- Human Microbiome, Diet and Cancerogenesis (Deadline: 30 April 2026)
- Interrogating Molecular Regulators and Chemical Agents in Brain Tumor Progression (Deadline: 30 April 2026)
- Inhibitors in Thyroid Carcinoma (2nd Edition) (Deadline: 24 May 2026)
- Decoding the Dynamic Matrix Complexity in Cancer (Deadline: 31 May 2026)
- Cellular Senescence, Aging and the Tumor Microenvironment in Cancer (Deadline: 31 May 2026)
- Role of Protein and Metabolite in Cancers (Deadline: 31 May 2026)
- Tumor Microenvironment in Ovarian Cancer Progression, Dissemination, Recurrence: Biology and Therapeutic Opportunities (Deadline: 31 May 2026)
- Role of Cytokines in Cancer (2nd Edition) (Deadline: 31 May 2026)
- Extracellular Vesicles in Cancer Progression (Deadline: 10 June 2026)
- Decoding and Remodeling the Suppressive Tumor Immune Microenvironment in Head and Neck Cancer (Deadline: 20 June 2026)
- Angiogenesis and Anti-Angiogenic Therapies in Cancer (Deadline: 24 June 2026)
- Epigenetic and Metabolic Alterations in the Tumor Microenvironment: 2nd Edition (Deadline: 26 June 2026)
- Redox Balance, Antioxidant Defenses, and Inflammation in Cancer: From Initial Changes to Tumor Progression (Deadline: 30 June 2026)
- Tumor Microenvironment of Thyroid Carcinoma (Deadline: 30 June 2026)
- Advances in Bacteria and Cancer (Deadline: 30 June 2026)
- Tumor Microenvironment (TME): Cellular and Molecular Interactions (Deadline: 30 June 2026)
- Calcium-Linked Messaging in Cancer (Deadline: 30 June 2026)
- Dendritic Cells and Immune Checkpoints Within the Tumor Microenvironment: Mechanisms, Models, and Therapy (Deadline: 30 June 2026)
- Modulating the Acidic Tumor Microenvironment to Enhance the Efficacy and Reduce the Toxicity of Cancer Treatment (Deadline: 30 June 2026)
- Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition) (Deadline: 30 June 2026)
- Class 2 Tumor Suppressor Gene Pathways for Therapeutic Applications in Hard-to-Treat Cancers (Deadline: 30 June 2026)
- Epigenetic Regulation in Hematologic Malignancies (Deadline: 30 June 2026)
- Signaling Networks Controlling Ovarian Cancer Progression and Response to Therapy (Deadline: 30 June 2026)
- Leukemia Cell Signaling Pathways: Recent Advances, Future Perspectives, and Potential Clinical Applications (Deadline: 30 June 2026)
- Tumor Microenvironment of Breast Cancer—2nd Edition (Deadline: 15 July 2026)
- Tumor Microenvironment of Gynecological Tumors (Deadline: 15 July 2026)
- Multiple Myeloma and Immunology: From Pathophysiology to Therapy (Deadline: 31 July 2026)
- Circulating Tumor DNA and Liquid Biopsy (Deadline: 31 July 2026)
- Redefining Cancer Through Its Microenvironment: Mechanisms, Modeling, and Targeting Strategies (Deadline: 31 July 2026)
- Crosstalk Mechanisms in Liver Cancer Microenvironments (Deadline: 31 July 2026)
- Tumor Microenvironment in Cancer Progression and Therapy Resistance (Deadline: 31 July 2026)
- The Tumor Microenvironment: Interplay Between Immune Cells (Deadline: 31 July 2026)
- Circulating Tumor Cells (CTCs) and the Implementation of Liquid Biopsy (2nd Edition) (Deadline: 31 July 2026)
- Tumorigenesis and Tumor Microenvironment—Insights and Interventions (TTMII) (Deadline: 31 July 2026)
- Decoding the Tumor Microenvironment: Immune Cell–Tumor Interplay in Breast Cancer (Deadline: 31 July 2026)
- Microsatellite Instability in Colorectal Cancer (Deadline: 31 July 2026)
- Targeted Therapies in Sarcomas: Overcoming Resistance and Improving Outcomes (Deadline: 8 August 2026)
- Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition) (Deadline: 30 August 2026)
- Tumor Microenvironment in Bone Sarcoma (Deadline: 31 August 2026)
- Tumor Microenvironment in Cancer Therapies: Supportive or Hostile? (Deadline: 31 August 2026)
- Roles of the Tumor Microenvironment on Liquid Biopsy (2nd Edition) (Deadline: 31 August 2026)
- Drug Resistance Mechanisms and Tumor Microenvironment in Upper Gastrointestinal Cancers (Deadline: 31 August 2026)
- The Development of Effective Therapy Targeting the Microenvironment of Cancer (2nd Edition) (Deadline: 30 September 2026)
- Tumor Microenvironment Dynamics in Hepatocellular Carcinoma (Deadline: 30 September 2026)
- Beyond PEGylation: Next-Generation Nanomedicine for Cancer Therapy (Deadline: 30 September 2026)
- Tumor-Initiating Cells in Cancer: Their Interactions with Other Cell Types, and Prospective Applications (Deadline: 30 September 2026)
- Extracellular Matrix Proteins in Cancer (2nd Edition) (Deadline: 30 September 2026)
- Tumor Microenvironment in Hematological Malignancies: Advances in Targeted Therapies and Cellular Mechanisms (Deadline: 30 September 2026)
- Breast Cancer Microenvironment: Molecular Mechanisms and Therapeutic Targeting (Deadline: 30 September 2026)
- Unraveling Immune Dynamics and Novel Therapeutic Strategies in the Tumor Microenvironment (Deadline: 30 October 2026)
- Decoding the Tumor Microenvironment: From Mechanisms to Therapeutic Opportunities (Deadline: 31 October 2026)
- The Tumor Microenvironment and Its Role in Tumor Growth and Angiogenesis—2nd Edition (Deadline: 31 October 2026)
- Targeting the Hypoxic Axis: HIF Signaling and Therapeutic Resistance in the Tumor Microenvironment (Deadline: 31 October 2026)
- Studies on Molecular Mechanisms in the Tumor Microenvironment (Deadline: 15 December 2026)
- Epitranscriptomics and the Tumor Microenvironment (Deadline: 25 December 2026)
- Tumor Microenvironment: Cellular Dynamics, Molecular Players, and Mechanisms of Therapy Resistance (Deadline: 31 December 2026)
- Cancer Cell Communications, Metastasis and Survival in the Host Microenvironment—2nd Edition (Deadline: 31 December 2026)
- Serum Biomarkers to Monitor Cancer Progression and Response to Therapy (Deadline: 31 December 2026)
Topical Collections
Following topical collections within this section are currently open for submissions: