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Cancers, Volume 18, Issue 5

2026 March-1 - 14 articles

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Articles (12)

  • Review
  • Open Access

24 February 2026

Philadelphia-Negative Myeloproliferative neoplasms (MPNs) are chronic clonal hematopoietic malignancies characterized by dysregulated myeloid proliferation, chronic inflammation, and an increased risk of thrombotic and hemorrhagic complications. In a...

  • Article
  • Open Access

24 February 2026

Background: Cancer screening disparities remain understudied, particularly among underrepresented groups at the county level. This study compared the use of preventive breast and colorectal cancer screening services between sexual and gender minority...

  • Article
  • Open Access

24 February 2026

Background/Objectives: The Iroquois (IRX) family of homeobox genes regulates critical developmental processes, and emerging evidence suggests that their dysregulation contributes to cancer progression, particularly in relation to cancer stemness. Alt...

  • Article
  • Open Access

18F-FDG PET/CT for Risk Stratification and Prognosis of Patients with Hypermetabolic Gastrointestinal Stromal Tumors

  • Li Zhang,
  • Yu Liu,
  • Chunxia Qin,
  • Huanyu Chen,
  • Yujun Wu,
  • Jinbo Gui,
  • Jingwen Wang,
  • Yong He,
  • Xiaoli Lan and
  • Wei Cao

24 February 2026

Objectives: We aimed to evaluate the value of various PET parameters derived from 18F- FDG PET/CT for risk stratification and prognosis of hypermetabolic gastrointestinal stromal tumors (GISTs). Methods: This study included 43 patients who underwent...

  • Review
  • Open Access

The Emerging Landscape of Respiratory Viral Infections in Immunocompromised Children

  • Paschalis Evangelidis,
  • Elias Iosifidis,
  • Athanasios Tragiannidis,
  • Emmanouel Hatzipantelis,
  • Emmanuel Roilides and
  • Maria Kourti

24 February 2026

Respiratory viral infections (RVIs) have been described traditionally as clinically important infectious complications in pediatric patients with immunosuppression, particularly in those with malignancies (hematological or solid) and recipients of he...

  • Article
  • Open Access

Improving Lung Cancer Screening Selection: A Comparative Analysis of Risk Models and Traditional Criteria in a Western European General Population

  • Danrong Zhong,
  • Grigory Sidorenkov,
  • Marcel J. W. Greuter,
  • Colin Jacobs,
  • Pim A. de Jong,
  • Hester A. Gietema,
  • Harry J. M. Groen,
  • Firdaus A. A. Mohamed Hoesein,
  • Noa Antonissen and
  • Geertruida H. de Bock
  • + 4 authors

24 February 2026

Background/Objectives: The objective of this study is to evaluate the performance of the traditional age/smoking criteria and existing risk prediction models in selecting high-risk populations for lung cancer screening from a Western European general...

  • Article
  • Open Access

DNMT3B Controls Enhancer-Linked Chromatin and Cell Cycle Networks in Acute Myeloid Leukemia

  • Arundhati Chavan,
  • Pritam Biswas,
  • Kimberly Stephens and
  • Samrat Roy Choudhury

24 February 2026

Background: DNMT3B is frequently overexpressed in molecular subsets of acute myeloid leukemia (AML) and is associated with poor prognosis. Unlike DNMT3A, DNMT3B is rarely mutated, suggesting dysregulation through epigenetic mechanisms. The regulatory...

  • Article
  • Open Access

Two-Stage Surgery in Patients with Diffuse Glioma—Indications, Implications and Outcome

  • Sebastian Jeising,
  • Johannes Reinken,
  • Marion Rapp,
  • Michael Sabel and
  • Franziska Staub-Bartelt

24 February 2026

Introduction: Significant studies have substantiated the evidence for complete resection of intrinsic brain tumours in recent years. However, achieving this through a single surgery is not always possible due to tumour localisation in eloquent areas....

  • Article
  • Open Access

24 February 2026

Background: Hepatocellular carcinoma (HCC) is a major cause of mortality in the United States, but it can be cured with orthotopic liver transplant (OLT) in selected patients. Despite curative intent, post-OLT recurrence can occur in up to 15% of pat...

  • Systematic Review
  • Open Access

24 February 2026

Background: A significant rise is observed in the incidence of early-onset colorectal cancer (EOCRC) worldwide, demanding discovery of promising non-invasive diagnostic biomarkers. This systematic review and meta-analysis evaluated the diagnostic acc...

  • Review
  • Open Access

24 February 2026

Cancer metastasis and chemoresistance are primary reasons for cancer-related mortality. Current therapeutic options rely mostly on single-target drugs, which often fail to exhibit long-lasting remission of the disease progression due to the complexit...

  • Review
  • Open Access

24 February 2026

Health-related quality of life is a multidimensional concept used to describe one’s well-being in relation to their disease. Individuals with gliomas, the most commonly occurring malignant primary brain tumor, experience a multitude of symptoms...

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Cancers - ISSN 2072-6694