Mastering the Immunosuppressive Tumor Microenvironment with Cancer Vaccines
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 7
Special Issue Editor
Interests: cancer therapeutic resistance; prostate & breast cancer mechanisms; natural product-based drug development; immunosuppressive tumor microenvironment; computational drug discovery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) is a major obstacle in cancer immunotherapy, largely because it actively suppresses immune responses. To make cancer vaccines more effective, we need innovative ways to disrupt or evade this immunosuppressive barrier. This Special Issue will highlight the latest advances in reprogramming TME to boost the power of both therapeutic and preventive cancer vaccines. We invite the submission of original research and in-depth reviews, covering new vaccine technologies, optimal antigen selection, improved adjuvants, advanced delivery systems, and combination strategies such as pairing vaccines with checkpoint inhibitors, cytokine therapies, or stromal-targeting agents. We are especially interested in studies that bridge lab discoveries with real-world clinical applications. Submissions on topics like tumor-infiltrating immune cells, metabolic and stromal influences on immunity, and personalized vaccine design are highly encouraged. By bringing together cutting-edge research, this Special Issue aims to uncover how cancer vaccines can transform the TME and trigger long-lasting anti-tumor immunity.
Dr. Prem Prakash Kushwaha
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- cancer vaccines
- immunosuppression
- immune modulation
- checkpoint inhibitors
- dendritic cell vaccines
- T cell activation
- personalized cancer immunotherapy
- vaccine adjuvants
- combination immunotherapy
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