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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanisms Underlying the Neuropathic/Chronic Pain Development and Maintenance: Focus on Pharmacological Targets and Therapeutic Approaches

edited by

Giada Amodeo

submission deadline 25 Oct 2025 | 1 articles | Viewed by 462 | Submission Open

Keywords: neuropathic pain; chronic pain; mood alteration; neurons; glia cells; cytokines; neuroinflammation

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Contributions of Multisensory Processing and Integration in Successful Ageing

edited by Argiro Vatakis

submission deadline 25 Oct 2025 | Viewed by 238 | Submission Open

Keywords: multisensory; sensory; ageing; multisensory integration; multisensory processing; healthy ageing

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Stroke: Epidemiology, Diagnosis, Etiology, Treatment, and Prevention

edited by Rubens José Gagliardi

submission deadline 30 Oct 2025 | Viewed by 159 | Submission Open

Keywords: stroke; cerebrovascular disease; epidemiology; thrombolysis; thrombectomy; risk factors; ischemia

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Non-Invasive Brain Stimulation

edited by

Mariagiovanna Cantone

and

Giuseppe Lanza

submission deadline 31 Oct 2025 | 2 articles | Viewed by 6244 | Submission Open

Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

How to Rewire the Brain—Neuroplasticity

edited by

Jianyang Du

and Hui Lu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4798 | Submission Open

Keywords: brain circuits; neural networks; synaptic plasticity; neural development; network dynamics; neural coding; information processing; neuron– glia interaction; behavioral output; neurological disorders

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Editorial Board Collection Series: Advances in Neuro-Oncology

edited by

Terry Lichtor

submission deadline 31 Oct 2025 | 5 articles | Viewed by 4322 | Submission Open

Keywords: brain tumors; gliomas; cytokine gene vaccine therapy; immunotherapy; angiogenesis; checkpoint inhibitors; dendritic cell therapy

(This special issue belongs to the Section Neuro-oncology)

Modulating Brain Network Dynamics Through Training: Impacts on Perception, Cognition, and Action in Health and Disorder

edited by

Mukesh Dhamala

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3475 | Submission Open

Keywords: perception; cognition; motor actions; behavioral training; music; video game playing; neuroimaging; computational models; physical exercise

(This special issue belongs to the Section Behavioral Neuroscience)

Molecular and Neuroimaging Biomarkers in Alzheimer’s Disease and Frontotemporal Lobar Degeneration

edited by

Rodolfo Gabriel Gatto

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1844 | Submission Open

Keywords: neuroimaging; biomarkers; genetic and molecular biology; connectomics; neuropathology; neuropsychological measures; dementia; preclinical models; alzheimer’ s disease; frontotemporal dementia

(This special issue belongs to the Section Neurodegenerative Diseases)

Neuroimaging and Biomarker-Guided Neuromodulation: Advances in Personalized Brain and Autonomic Stimulation

edited by Mohsen Mosayebi-Samani and

Desmond Agboada

submission deadline 31 Oct 2025 | 1 articles | Viewed by 775 | Submission Open

Keywords: neuromodulation; brain stimulation; autonomic regulation; neuroimaging; biomarkers; AI-driven Closed-loop Systems; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); deep brain stimulation (DBS); transcranial ultrasound stimulation (TUS); vagus nerve stimulation (tVNS); heart rate variability (HRV); biofeedback; magnetic resonance imaging (MRI); electroencephalography (EEG); functional near-infrared spectroscopy (fNIRS); epilepsy; depression; stroke; Alzheimer; PTSD; anxiety

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Understanding Human Social Cognition: Integration of Neural, Cognitive, Behavioral, Affective, and Social Determinants

edited by

Eduar Herrera

submission deadline 31 Oct 2025 | 1 articles | Viewed by 774 | Submission Open

Keywords: social cognition; neural; cognitive; affective; social determinants

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

The Impact of Self and Reward on Cognitive Processes

edited by Ada Kritikos

submission deadline 31 Oct 2025 | Viewed by 301 | Submission Open

Keywords: self-prioritisation; memory self-reference effects; source and recognition memory; decision making; value modulated attentional capture; reward bias; ownership; self-evaluation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Advancements and Future Directions in Real-Time fMRI Neurofeedback Research

edited by Meghan Martz, Scott Peltier and Stefanie Russman Block

submission deadline 31 Oct 2025 | Viewed by 259 | Submission Open

Keywords: neurofeedback; real-time fMRI; neuromodulation; imaging methods; self-regulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Exploring the Neurobiology of the Sensory-Motor System

edited by

Daya Shankar Gupta

and Hubert Löffler

submission deadline 31 Oct 2025 | Viewed by 146 | Submission Open

Keywords: sensory; perception; motor; execution; cognitive functions; space of the brain; temporal-spatial; time dimension

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Emotional Recognition and Behavioral Regulation: An Integral Perspective

edited by

Ángel Romero Martínez

submission deadline 31 Oct 2025 | Viewed by 131 | Submission Open

Keywords: behavioral regulation; emotion decoding; emotion recognition; mental disorders; personality disorders; violence

(This special issue belongs to the Section Neuropsychology)

From Diagnosis to Care: Cognitive Challenges and Innovations in Multiple Sclerosis

edited by

Adriana Aguayo-Arelis

and Brenda Viridiana Rabago-Barajas

submission deadline 31 Oct 2025 | Viewed by 118 | Submission Open

Keywords: multiple sclerosis; neuropsychological diagnosis; diagnostic biomarkers; cognition and care; research on neurodegenerative diseases

(This special issue belongs to the Section Systems Neuroscience)

Ferroptosis in Epilepsy: From Molecular Mechanisms to Possible Therapeutic Alternatives

edited by

Alberto Lazarowski

and Jerónimo Andrés Auzmendi

submission deadline 31 Oct 2025 | Viewed by 90 | Submission Open

Keywords: epilepsy; ferroptosis; hypoxia; brain parenchyma; peripheral organs; iron metabolism; transferrin; hemosiderin

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Artificial Intelligence in Neuropsychology: Advancing Diagnosis, Personalized Treatment, and Predictive Modeling

edited by

Sara Palermo

submission deadline 1 Nov 2025 | Viewed by 173 | Submission Open

Keywords: AI-driven diagnostic tools; personalized treatment; machine learning predictive modeling; data analysis; mental health and rehabilitation; decision support systems

(This special issue belongs to the Section Neuropsychology)

The Neural Processes Underlying Parkinson’s Disease and Related Synucleinopathies

edited by Danielle E. Mor

submission deadline 5 Nov 2025 | Viewed by 202 | Submission Open

Keywords: α -synuclein; synucleinopathies; Parkinson’ s disease; dementia with Lewy bodies; multiple system atrophy; neurodegeneration; protein aggregation

(This special issue belongs to the Section Neurodegenerative Diseases)

Application of MRI in Brain Diseases

edited by

Carlo A. Mallio

Gianfranco Di Gennaro

and Andrea Elefante

submission deadline 6 Nov 2025 | 4 articles | Viewed by 2149 | Submission Open

Keywords: magnetic resonance imaging (MRI); medical imaging; neurological disorders; mental disorders; brain diseases; diagnosis; treatment

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Clinical Studies in Alcohol Use Disorders

edited by Łukasz Mokros and

Katarzyna Nowakowska-Domagała

submission deadline 10 Nov 2025 | Viewed by 490 | Submission Open

Keywords: AUD; suicide; suicidality; sleep; circadian rhythm; addiction therapy; cognitive functions; psychotherapy; trauma

(This special issue belongs to the Section Behavioral Neuroscience)

Deep into the Brain: Artificial Intelligence in Brain Diseases—2nd Edition

edited by

Gianluca Borghini

Pietro Aricò

Gaia Romana Pellicano

and

Alessandra Anzolin

submission deadline 15 Nov 2025 | 3 articles | Viewed by 7808 | Submission Open

Keywords: artificial intelligence; brain diseases; neurological disorders; machine learning; deep learning; neuroimaging; neuroscience; neurophysiological measures; mental states; multimodal approach

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

New Advances in Surgical Treatment of Brain Injury

edited by

Andres M. Rubiano

and Luigi Valentino Berra

submission deadline 15 Nov 2025 | 1 articles | Viewed by 1975 | Submission Open

Keywords: traumatic brain injury; intracranial compartment syndrome; invasive monitoring; non-invasive neuroimaging; decompressive craniectomy; expansion craniotomy; hinge craniotomy; endoscopic neurosurgery; brain injury management

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Molecular Genetics of Neurodevelopment Disorders

edited by

Constance Smith-Hicks

and

Philip H. Iffland

submission deadline 15 Nov 2025 | 1 articles | Viewed by 794 | Submission Open

Keywords: genotype– phenotype correlations; epigenetics; genome editing; translational research; neuroethics; deep sequencing; functional genomics

(This special issue belongs to the Section Developmental Neuroscience)

The Interplay Between the Brain, Behavior and Immunity

edited by

Fatme Seval Ismail

submission deadline 15 Nov 2025 | Viewed by 138 | Submission Open

Keywords: behavior; therapy; drugs; immunity; neuroinflammation; neurological/psychiatric disorders; clinical studies; in vivo/in vitro models

(This special issue belongs to the Section Behavioral Neuroscience)

Using Neuroimaging Techniques to Explore the Diagnosis and Treatment of Epilepsy

edited by Friedhelm C. Schmitt

submission deadline 15 Nov 2025 | Viewed by 36 | Submission Open

Keywords: neuroimaging; epilepsy; MRI; PET; MEG

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Translational Omics in Neurodegenerative and Neurodevelopmental Disorders

edited by

Shiek S.S.J. Ahmed

and

Prabu Paramasivam

submission deadline 17 Nov 2025 | 3 articles | Viewed by 7975 | Submission Open

Keywords: Neurodegeneration; Neurodevelopment; Omics; Translation regulation; Diagnostic biomarkers; Therapeutic targets

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Computational Neuroscience and Artificial Intelligence: Cross-Talks and Interrelated Contributions

edited by

Ali Yadollahpour

submission deadline 17 Nov 2025 | 5 articles | Viewed by 7277 | Submission Open

Keywords: computational neuroscience; cognitive neuroscience; artificial intelligence; machine learning; precision medicine; early diagnosis; treatment

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Retinal Neurochemistry and Development

edited by Roberto Paes-de-Carvalho and Sriparna Majumdar

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3175 | Submission Open

Keywords: retina; neurochemistry; development; neurotransmitter; signaling pathways; cultures; neuron– glia interactions; synapses; neuronal differentiation; neuritogenesis

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Application of Transcranial Magnetic Stimulation (TMS) in Motor Control and Learning

edited by

Sean Meehan

submission deadline 20 Nov 2025 | 1 articles | Viewed by 710 | Submission Open

Keywords: transcranial magnetic stimulation; non-invasive; motor; sensorimotor; intracortical; neuroplasticity; basic neuroscience; clinical neuroscience; dual-site TMS

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Diagnosis and Treatment of Post-Stroke and Progressive Aphasias

edited by Sigfus Kristinsson and Sladjana Lukic

submission deadline 20 Nov 2025 | Viewed by 331 | Submission Open

Keywords: post-stroke aphasia; primary progressive aphasia; lesion– symptom mapping; neuroimaging; speech and language treatment; neural markers

(This special issue belongs to the Section Neurolinguistics)

Neuropsychological Exploration of Spatial Cognition and Navigation

edited by

Jose Manuel Cimadevilla

Laura Piccardi

Raffaella Nori

Maria Kozhevnikov

and Sean Commins

submission deadline 21 Nov 2025 | 2 articles | Viewed by 1460 | Submission Open

Keywords: spatial memory; neuropsychological; spatial navigation; cognitive disorder; Alzheimer’ s disease; spatial cognition; dementia; brain Function

(This special issue belongs to the Section Neuropsychology)

New Horizons in Multisensory Perception and Processing—2nd Edition

edited by

Sara Invitto

submission deadline 24 Nov 2025 | Viewed by 142 | Submission Open

Keywords: chemosensory perception; multisensory perception; haptic perception; auditory perception; multisensory processing

(This special issue belongs to the Section Behavioral Neuroscience)

Advances in Emotion Processing and Cognitive Neuropsychology

edited by

Pasquale La Malva

submission deadline 25 Nov 2025 | 1 articles | Viewed by 1471 | Submission Open

Keywords: emotion processing; cognitive neuropsychology; affective neuroscience; emotion regulation; executive functions; neuroimaging (fMRI; EEG); non-invasive brain stimulation (TMS; tDCS); psychophysiological measures; age-related differences; translational research

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Blood–Brain Barrier: Latest Research

edited by Richard A. Hawkins and Jacinthe Gingras

submission deadline 25 Nov 2025 | Viewed by 74 | Submission Open

Keywords: central nervous system; blood– brain barrier transport; receptor; transcytosis; therapeutic; neurovascular unit; translation; development; disease; membranes; astrocytes; nutrient; homeostasis

(This special issue belongs to the Section Systems Neuroscience)

Advancements in Diagnosis and Treatment of Stroke and Cerebral Aneurysms: A Call for Innovative Research Submissions

edited by

Sherief Ghozy

, Ram Kadirvel and Ajay Malhotra

submission deadline 28 Nov 2025 | 4 articles | Viewed by 6298 | Submission Open

Keywords: stroke; cerebral aneurysms; minimally invasive surgical; imaging; neurovascular

(This special issue belongs to the Section Neurorehabilitation)

Relationships Between Disordered Sleep and Mental Health

edited by Anne M. Fink

submission deadline 28 Nov 2025 | 2 articles | Viewed by 3713 | Submission Open

Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide

(This special issue belongs to the Section Neuropsychiatry)

The Neuroscience of Decision-Making: Linking the Brain, Behavior, and Society

edited by Bruno Kluwe-Schiavon and Giorgio Manenti

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1747 | Submission Open

Keywords: decision-making; neural circuits; social cognition; moral dilemmas; adaptive behaviors; biopsychosocial factors

(This special issue belongs to the Section Behavioral Neuroscience)

Defining Emotion: A Collection of Current Models

edited by

Peter Walla

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1317 | Submission Open

Keywords: emotion; affect; affection; affective processing of feelings; mood; cognitive processing

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Frontotemporal Dementia: Behavioural and Neuroimaging Studies

edited by

Leonardo Cruz de Souza

submission deadline 30 Nov 2025 | 1 articles | Viewed by 994 | Submission Open

Keywords: frontotemporal dementia; neuroimaging; behaviour

(This special issue belongs to the Section Neurodegenerative Diseases)

Editorial Board Collection Series: Neuro-Otorhinolaryngology—Bridging Sensory Impairments and Central Nervous System Disease in the Head and Neck

edited by

Arianna Di Stadio

Evanthia Bernitsas

and

Michael J. Brenner

submission deadline 30 Nov 2025 | Viewed by 234 | Submission Open

Keywords: hearing loss; vertigo; dysphonia; dysphagia; imbalance; tinnitus; hyposmia; parosmia

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Generality and Specificity of Reading Processes

edited by Sendy Caffarra

submission deadline 30 Nov 2025 | Viewed by 159 | Submission Open

Keywords: reading; assessment; training; development; acquisition; behavior; electrophysiology; neuroimaging

(This special issue belongs to the Section Neurolinguistics)

Drug Development for Schizophrenia

edited by

Alessio Mosca

submission deadline 30 Nov 2025 | Viewed by 115 | Submission Open

Keywords: antipsychotics; biomarkers; glutamatergic modulation; schizophrenia treatment; drug discovery

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Novel Therapeutic Approaches for Treatment-Resistant Depression

edited by Yuliya O. Knyahnytska

submission deadline 30 Nov 2025 | Viewed by 82 | Submission Open

Keywords: treatment resistant depression; hard-to-treat mood disorders; innovative interventions; therapeutic brain stimulation interventions; neuromodulation interventions; novel psychotropics

(This special issue belongs to the Section Neuropsychiatry)

Chronic Non-Infectious Diseases with a High Impact on the Central Nervous System

edited by

Grazyna Lietzau

submission deadline 5 Dec 2025 | 5 articles | Viewed by 5155 | Submission Open

Keywords: mental disorders; metabolic diseases; migraine; movement disorders; multiple sclerosis; neurodegenerative diseases; stroke

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advances in Cognitive and Psychometric Evaluation

edited by

Rubén Trigueros Ramos

José M. Aguilar-Parra

and

Rocío Collado-Soler

submission deadline 10 Dec 2025 | 1 articles | Viewed by 646 | Submission Open

Keywords: cognitive assessment; psychometric evaluation; measurement innovation; advanced data analysis; affective assessment

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Pharmacy and Mental Health

edited by

Kyle Burghardt

submission deadline 10 Dec 2025 | Viewed by 59 | Submission Open

Keywords: pharmacy; mental health; pharmacists

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Interoception and Women’s Health

edited by

Jennifer Todd

and Jennifer Murphy

submission deadline 12 Dec 2025 | 1 articles | Viewed by 13574 | Submission Open

Keywords: interoception; women’ s health; sex differences; healthcare disparities; reproductive health

(This special issue belongs to the Section Neuropsychology)

The Use of Robotics and Artificial Intelligence in Neurorehabilitation: From Diagnosis to Treatment

edited by

Rocco Salvatore Calabrò

David Perpetuini

and

Irene Aprile

submission deadline 15 Dec 2025 | 5 articles | Viewed by 13110 | Submission Open

Keywords: robotic-assisted rehabilitation; machine learning; neurological disorders; artificial intelligence

(This special issue belongs to the Section Neurorehabilitation)

Neuromodulation for Pain Management: Evidence of Safety and Efficacy

edited by

Andrés Molero-Chamizo

and Rafael Tomás Andújar-Barroso

submission deadline 15 Dec 2025 | 4 articles | Viewed by 2798 | Submission Open

Keywords: chronic pain; clinical neurostimulation; invasive neuromodulation; neurostimulation-induced plasticity; non-invasive neuromodulation; pain management; transcranial electric stimulation; transcranial magnetic stimulation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Machine Learning and Artificial Intelligence Algorithms in Neuroscience

edited by Mohsen Ahmadi

submission deadline 15 Dec 2025 | 1 articles | Viewed by 972 | Submission Open

Keywords: machine learning; artificial intelligence; computational neuroscience; deep learning; neuroimaging; brain– computer interfaces; neural signal processing; cognitive modeling; neurodegenerative diseases; explainable AI

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

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