Special Issues

Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders
edited by and Ana Lucia De Paul
submission deadline 31 Dec 2025 | 1 articles | Viewed by 791 | Submission Open
Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Lifestyle and Risk Factors for Multiple Sclerosis submission deadline 31 Dec 2025 | Viewed by 521 | Submission Open
Keywords: multiple sclerosis; lifestyle; risk factors; nutrition; pollution; sleep quality; progression
(This special issue belongs to the Section Neurodegenerative Diseases)
Neuroscience of Learning, Mental Health, and Cultural Adaptation: Cognitive, Pedagogical, and Psychological Perspectives submission deadline 31 Dec 2025 | Viewed by 317 | Submission Open
Keywords: cognitive neuroscience; mental health and learning; cultural adaptation; educational neuroscience; neuropsychology of learning; pedagogical interventions; emotional resilience in education; multicultural and inclusive education; neural mechanisms of learning; cross-cultural pedagogy
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Quantifying Motor Neurone Disease: Advances and Challenges in Developing Biomarkers, Predictive Models and Outcome Measures
edited by Roisin McMackin and
submission deadline 31 Dec 2025 | Viewed by 222 | Submission Open
Keywords: amyotrophic lateral sclerosis; primary lateral sclerosis; progressive muscular atrophy; biomarkers (cognition; neurophysiology; biofluid markers; neuroimaging); modelling; therapeutic development; early detection and diagnosis; precision medicine
(This special issue belongs to the Section Sensory and Motor Neuroscience)
New Advances in Functional Neurosurgery—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 199 | Submission Open
Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Advanced Neuromodulation Therapies for Chronic Pain and Psychiatric Disorders
edited by and Marina de Goes Salvetti
submission deadline 31 Dec 2025 | Viewed by 100 | Submission Open
Keywords: repetitive transcranial magnetic stimulation (rTMS); theta burst stimulation (TBS); chronic pain; treatment-resistant depression; neuromodulation; tDCS; tACS; non-invasive brain stimulation; neuroplasticity; functional connectivity; major depressive disorder and generalized anxiety disorder
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Applications of Cognitive Behavioral Therapy in Mental Disorders
edited by Maria Rita Sergi
submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open
Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions
Multiple Sclerosis Across the Age Spectrum—Beyond Inflammation
edited by
submission deadline 1 Jan 2026 | Viewed by 75 | Submission Open
Keywords: multiple sclerosis; neurodegeneration; disability; cognition; functional outcomes; rehabilitation; pediatric-onset; late onset; ageing
Neural Mechanisms Underlying Social Cognition and Emotional Processing
edited by
submission deadline 10 Jan 2026 | Viewed by 298 | Submission Open
Keywords: social cognition; emotional processing; social neuroscience; developmental neuroscience
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Deep Research into Stroke
edited by
submission deadline 15 Jan 2026 | 2 articles | Viewed by 2389 | Submission Open
Keywords: stroke; rehabilitation; neuromodulation; physical therapy; robotics; artificial intelligence; neuroimaging; deep learning; machine learning; exercise
(This special issue belongs to the Section Neurorehabilitation)
Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease
edited by Yuta Katsumi, and Bradford C. Dickerson
submission deadline 15 Jan 2026 | 2 articles | Viewed by 1424 | Submission Open
Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Beyond Boundaries: Current Advances in Developmental Learning Disorders
edited by Daniela Traficante and
submission deadline 15 Jan 2026 | Viewed by 162 | Submission Open
Keywords: developmental learning disorders; transdiagnostic approach; comorbidity; domain-general components
(This special issue belongs to the Section Neuropsychology)
Non-Invasive Neurotechnologies for Cognitive Augmentation submission deadline 15 Jan 2026 | Viewed by 90 | Submission Open
Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Inflammation and Central Nervous System
edited by
submission deadline 15 Jan 2026 | Viewed by 83 | Submission Open
Keywords: inflammation; inflammasome; brain injury; neurodegeneration; aging; cognition; brain senescence
(This special issue belongs to the Section Systems Neuroscience)
Anxiety, Depression and Stress
edited by
submission deadline 18 Jan 2026 | 3 articles | Viewed by 2387 | Submission Open
Keywords: anxiety; depression; stress; NMDA modulators; brain stimulation; anti-inflammatory agents; psychosocial interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Perception Across Disciplines: Exploring the Intersections of Cognitive, Social, Affective and Neural Dimensions
edited by
submission deadline 18 Jan 2026 | 1 articles | Viewed by 1129 | Submission Open
Keywords: sensory processing; cognitive systems; perception-action binding; multimodal processing; neural foundations; socio-affective systems; computational models; interdisciplinary research
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition
edited by
submission deadline 20 Jan 2026 | 4 articles | Viewed by 8642 | Submission Open
Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Brain Boosting: Recent Advances in Neurostimulation on Cognitive Functions and Behavioral Performance
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 2035 | Submission Open
Keywords: TMS; cognitive functions; behavioral interventions; brain plasticity; addictions; hypnosis; neurostimulation
(This special issue belongs to the Section Behavioral Neuroscience)
Translational EEG Biomarkers in Animal Models: Bridging Pre-Clinical Findings to Human Neuroscience
edited by and Cestmir Vejmola
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1535 | Submission Open
Keywords: EEG; ECoG; biomarker; animal model; pre-clinical
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Advances in the Treatment of Depression, Anxiety, and Other Psychiatric Disorders
edited by Danielle S. Cha
submission deadline 20 Jan 2026 | Viewed by 316 | Submission Open
Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease
(This special issue belongs to the Section Neuropsychiatry)
Neuropathic Pain: Pathophysiology, Diagnosis and Treatment
edited by Marcos Brioschi and
submission deadline 20 Jan 2026 | Viewed by 84 | Submission Open
Keywords: neuropathic pain; pathophysiology; diagnosis; neuroimaging; thermography; artificial intelligence; treatment; rehabilitation; translational research; neuromodulation
(This special issue belongs to the Section Sensory and Motor Neuroscience)
The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System
edited by
submission deadline 23 Jan 2026 | 2 articles | Viewed by 5278 | Submission Open
Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Emerging Trends in Youth Mental Health
edited by
submission deadline 23 Jan 2026 | 1 articles | Viewed by 728 | Submission Open
Keywords: mental health; adolescent mental health; young adult; stress; psychological; social media; climate change; identity development; digital health; school health services
(This special issue belongs to the Section Neuropsychology)
Assessment and Rehabilitation of Cognitive Function in Neurological Disorders
edited by Gilles Naeije
submission deadline 25 Jan 2026 | 1 articles | Viewed by 818 | Submission Open
Keywords: post-stroke cognitive impairment; diaschisis; cerebellum; cortico-cerebellar connectivity; neuromodulation; transcranial cerebellar stimulation; cognitive rehabilitation; functional connectivity
(This special issue belongs to the Section Neurorehabilitation)
Advances in Neurofeedback Research
edited by
submission deadline 25 Jan 2026 | 1 articles | Viewed by 689 | Submission Open
Keywords: neurofeedback; brain– computer interface; neurophenomenology; EEG; rt-fMRI; fNIRS-neurofeedback
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Current Research in Neurosurgery
edited by , Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque
submission deadline 30 Jan 2026 | 8 articles | Viewed by 9089 | Submission Open
Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Brain Tumors: From Molecular Basis to Therapy
edited by Paolo Tini and Giuseppe Minniti
submission deadline 30 Jan 2026 | 5 articles | Viewed by 6671 | Submission Open
Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance
(This special issue belongs to the Section Neuro-oncology)
Advances in the Relationship Among Brain, Physical Function, and Exercise Performance
edited by
submission deadline 30 Jan 2026 | 3 articles | Viewed by 3890 | Submission Open
Keywords: physical performance; dual task; cognition; sport; environment; cerebellum; movement; neurodegenerative disease
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Management of Acute Stroke
edited by and Ali Hammed
submission deadline 30 Jan 2026 | 4 articles | Viewed by 2640 | Submission Open
Keywords: management in acute stroke care; thrombolysis; mechanical thrombectomy; epidemiology in stroke care; stroke unit; cerebral infarction; intracranial bleeding; therapy in acute stroke
(This special issue belongs to the Section Systems Neuroscience)
The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 15285 | Submission Open
Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes
(This special issue belongs to the Section Sleep and Circadian Neuroscience)
Advances in Memory and Cognitive Decline Associated with Aging and Alzheimer's Disease
edited by
submission deadline 31 Jan 2026 | 8 articles | Viewed by 14917 | Submission Open
Keywords: neurodegeneration; neuroprotection; neurogenesis; learning and memory; engram; neuro-vascular
(This special issue belongs to the Section Neurodegenerative Diseases)
Advanced Clinical Diagnosis, Evaluation, and Treatment of Psychosis
edited by Giulia Menculini and
submission deadline 31 Jan 2026 | 5 articles | Viewed by 10763 | Submission Open
Keywords: psychotic disorders; affective psychoses; schizophrenia; antipsychotic drugs; psychosocial treatments; at-risk mental states; biomarkers; early intervention; prevention; social psychiatry
(This special issue belongs to the Section Neuropsychiatry)
Advances in the Diagnosis, Visualization and Treatment of Intracranial Aneurysms and Subarachnoid Hemorrhage
edited by and Lukas Andereggen
submission deadline 31 Jan 2026 | 2 articles | Viewed by 1457 | Submission Open
Keywords: neurovascular; intracranial aneurysm; subarachnoid hemorrhage; education and teaching; imaging technology; hybrid operating room; augmented reality; cerebrovascular disease; cost-effectiveness; artificial intelligence
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Outcome Measures in Rehabilitation submission deadline 31 Jan 2026 | 1 articles | Viewed by 1335 | Submission Open
Keywords: outcome measures; qualitative measures; quantitative measures; neurologic rehabilitation; musculoskeletal rehabilitation; cardiopulmonary rehabilitation; robotic rehabilitation; movement analysis; gait analysis
(This special issue belongs to the Section Neurorehabilitation)
The Eye as the Window to Brain Science: Fields of Neuroscience Created from Eye Research
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 1207 | Submission Open
Keywords: sensory system functions; neuroanatomy; neurochemistry; neurophysiology; developmental neurobiology; neurological health and disease
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Mechanisms That Support Music Learning and Development
edited by Jennifer A. Bugos
submission deadline 31 Jan 2026 | Viewed by 257 | Submission Open
Keywords: music; music therapy; neurophysiological research; cognitive development; music cognition; performance; auditory processing
(This special issue belongs to the Section Behavioral Neuroscience)
Deep Brain Stimulation (DBS)—Current Status and Future Directions
edited by Yousef Salimpour
submission deadline 31 Jan 2026 | Viewed by 49 | Submission Open
Keywords: deep brain stimulation; neuromodulation; adaptive closed-loop systems; directional leads; neural biomarkers artificial intelligence; personalization treatment; biocompatible materials
(This special issue belongs to the Section Neurodegenerative Diseases)
Translational Neuroanatomy: Recent Updates and Future Perspectives—2nd Edition
edited by and Andrzej Żytkowski
submission deadline 10 Feb 2026 | 1 articles | Viewed by 101 | Submission Open
Keywords: neuroanatomy; clinical neuroscience; central or peripheral nervous system
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Feb 2026 | Viewed by 87 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innovative diagnostic tools
Novel Insights into Developmental Coordination Disorder
edited by Rita C Silveira and
submission deadline 10 Feb 2026 | Viewed by 60 | Submission Open
Keywords: neurodevelopment; prematurity; developmental coordination disorder (DCD); executive function; life-course trajectories; mental health; brain development
(This special issue belongs to the Section Developmental Neuroscience)
Neuropathic Pain: From Physiopathology to Improvements in Diagnosis and Management
edited by Caren Tatiane De David Antoniazzi and Patricia Rodrigues
submission deadline 15 Feb 2026 | Viewed by 142 | Submission Open
Keywords: neuropathic pain; pain mechanisms; neuroinflammation; sensitization; biomarkers; chronic pain; somatosensory system; pain diagnosis; personalized medicine; pain management
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Critical Issues in Motor Control and Sensory–Motor Integration
edited by Simone Gill
submission deadline 15 Feb 2026 | Viewed by 69 | Submission Open
Keywords: motor control; sensorimotor; multisensory; human movement
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Somatosensory Evoked Potentials: Beyond Somesthesis
edited by Ana Maria Cebolla and Guy Cheron
submission deadline 15 Feb 2026 | Viewed by 65 | Submission Open
Keywords: somatosensory evoked potentials; EEG; brain oscillations; movement; gating; modified consciousness states; motor learning
(This special issue belongs to the Section Systems Neuroscience)
Migraine Management: Exploring Neural Clues
edited by Soma Sahai-Srivastava
submission deadline 15 Feb 2026 | Viewed by 44 | Submission Open
Keywords: migraine management; translational research; non-drug treatment; neural cues; non-pharmacological treatment
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
The Role of Glia in Inflammatory Processes
edited by and Margarete Dulce Bagatini
submission deadline 16 Feb 2026 | 4 articles | Viewed by 4839 | Submission Open
Keywords: neuroinflammation; neurodegenerative and psychiatric disorders; microglia; astrocytes; purinergic signaling; bioactive and natural compounds; immunopharmacology and immunotoxicology; oxidative and nitrosative stress; neuroimaging; neuroscience and behavior
(This special issue belongs to the Section Neuroglia)
Language, Communication and the Brain—2nd Edition submission deadline 20 Feb 2026 | 2 articles | Viewed by 1978 | Submission Open
Keywords: cognitive; attention; working memory; executive functions; linguistic; language planning; speech production; fluency; sensorimotor; hearing; speech and language production; neurotypical; neurodiverse; autism; apraxia; dysarthria; stuttering; speech sound disorders; artificial intelligence; data science; theoretical; data-driven
(This special issue belongs to the Section Neurolinguistics)
Advanced Technologies and Approaches for Understanding and Treating Psychological Disorders submission deadline 20 Feb 2026 | 1 articles | Viewed by 1382 | Submission Open
Keywords: psychological disorders; psychological well-being; psychological interventions; non-invasive brain stimulation; digital therapies; artificial intelligence; virtual reality; pharmacological interventions
(This special issue belongs to the Section Neuropsychiatry)
Advances in Cerebral Aneurysm Surgery: The Latest Technologies and Techniques
edited by Andreas Gruber
submission deadline 20 Feb 2026 | Viewed by 86 | Submission Open
Keywords: microsurgical aneurysm clipping; preoperative simulation; hybrid neurovascular surgery; skills-lab training; intraoperative monitoring and imaging
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Non-Invasive Neural Technology in Analysing Spinal Cord Activity
edited by
submission deadline 20 Feb 2026 | Viewed by 51 | Submission Open
Keywords: spinal cord; non-invasive recording; electrophysiology; neurotechnology; signal processing; artifact reduction; wearable sensors; machine learning
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Cognitive Training in Health and Disease submission deadline 22 Feb 2026 | Viewed by 61 | Submission Open
Keywords: cognitive training; child development; adolescence; executive functions; cognitive stimulation; mental health; neurodevelopmental disorders; healthy aging; education and cognition
(This special issue belongs to the Section Cognitive Neuroscience)
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