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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mindfulness and Emotion Regulation

edited by

Ciro Conversano

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1025 | Submission Open

Keywords: mindfulness; emotion regulation; affective neuroscience; emotional cognition; interoception; contemplative practices; psychophysiology; neural plasticity; stress reactivity; self-regulation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Next-Generation Tools in Neurosurgery: Robotics, Imaging and Beyond

edited by Salvatore M. Cardali and

Giada Garufi

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1025 | Submission Open

Keywords: neurosurgery; robotics; artificial intelligence; AI; neuronavigation; augmented reality

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Examining Executive Function in Early Childhood: Context, Individual Differences and Interventions

edited by

Lisa Boyce

and Sophia D'Agostino

submission deadline 15 Sep 2026 | Viewed by 475 | Submission Open

Keywords: early childhood; cognitive development; executive function; early intervention; developmental trajectories; neurodevelopment

(This special issue belongs to the Section Behavioral Neuroscience)

The Neural Processes Underlying the Sensorimotor System and Cognitive Function

edited by Francesca Ginatempo

submission deadline 15 Sep 2026 | Viewed by 248 | Submission Open

Keywords: sensory system; motor system; cognitive function; connectivity; neurologic disorders; Alzheimer’ s disease; embodied simulation; psychiatric disorder; neurophysiology; neuroimaging

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neural Substrates of Opioid Reward and Addiction: From Bench to Bedside

edited by

Kabirullah Lutfy

and

Syed Muzzammil Ahmad

submission deadline 15 Sep 2026 | Viewed by 209 | Submission Open

Keywords: opioids; neuropeptides; pain; reward; dependence; withdrawal; addiction; side effects

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Neural and Muscular Plasticity in Motor and Postural Control

edited by

Thierry Paillard

submission deadline 25 Sep 2026 | 3 articles | Viewed by 2279 | Submission Open

Keywords: postural balance; motor behaviour; movement; posture; postural adjustments; neural plasticity; perception; sensory integration; intermuscular coordination

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Clinical Research on Psychotic Disorders: Advances and Challenges

edited by

Robert Pudlo

and

Szymon Florek

submission deadline 25 Sep 2026 | 1 articles | Viewed by 577 | Submission Open

Keywords: psychotic disorders; schizophrenia; clinical research; early intervention; biomarkers; treatment outcomes; pharmacotherapy; mental health

(This special issue belongs to the Section Neuropsychiatry)

Anesthesia in Clinical Neuroscience: Neurotoxicity, Consciousness and Recovery

edited by Natesh Yepuri

submission deadline 26 Sep 2026 | Viewed by 210 | Submission Open

Keywords: neurotoxicity; intra-operative awareness; PTST; delirium agitation; emergence delirium

(This special issue belongs to the Section Systems Neuroscience)

Advances in Parkinson's Disease and Movement Disorders

edited by

Gabriele Imbalzano

and Domiziana Rinaldi

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2384 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; biomarkers; device-aided therapies; genetics; disease-modifying therapies; digital health technologies; neuromodulation

(This special issue belongs to the Section Neurodegenerative Diseases)

Advanced Image-Guided Neurosurgery: Brain Mapping and Intraoperative Imaging Innovations

edited by Prashin Unadkat and Yoonbae Oh

submission deadline 30 Sep 2026 | Viewed by 327 | Submission Open

Keywords: neurosurgery; intraoperative imaging; brain mapping; multimodal imaging; AI-driven image analysis; stereotactic neurosurgery; imaging biomarkers

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

The Right Hemisphere: Is It Really the Secondary Hemisphere?

edited by

Simona Spaccavento

and Pasquale Moretta

submission deadline 30 Sep 2026 | Viewed by 268 | Submission Open

Keywords: right hemisphere; stroke; attention deficits; neglect; visuospatial deficits; emotions; communication; social cognition; functional outcome

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Mechanisms and Applications of Vagus Nerve Stimulation in Neuroplasticity and Neurorehabilitation

edited by

Matteo Maria Ottaviani

submission deadline 30 Sep 2026 | Viewed by 257 | Submission Open

Keywords: vagus nerve stimulation; neuroplasticity; neurorehabilitation; neuromodulation; stroke recovery; traumatic brain injury; cortical reorganization; autonomic nervous system; bioelectronic medicine

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Unraveling Brain Networks in Epilepsy with Advanced Imaging and Monitoring Technology

edited by

Fabrice Bartolomei

submission deadline 30 Sep 2026 | Viewed by 256 | Submission Open

Keywords: focal epilepsy; network; functional connectivity; signal analysis; graph theory; epileptogenesis; neuromodulation; sleep

(This special issue belongs to the Section Systems Neuroscience)

Neural Oscillations in Cognition and Behavior

edited by

Yalda Shahriari

submission deadline 30 Sep 2026 | Viewed by 220 | Submission Open

Keywords: cross-frequency coupling; cognitive processes; behavior; electrophysiology; hemodynamic imaging; multimodal integration; neural dynamics; signal processing; computational modeling; machine learning; neuroimaging methods

(This special issue belongs to the Section Behavioral Neuroscience)

Neuroimaging and Neuromodulation in Movement Disorders

edited by

Jae Woo Chung

submission deadline 30 Sep 2026 | Viewed by 218 | Submission Open

Keywords: movement disorders; neuroimaging; Parkinson’ s disease; dystonia; tremor; EEG; TMS; tES; DBS; MRI

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Personality Disorders

edited by Nathan J. Kolla

submission deadline 30 Sep 2026 | Viewed by 216 | Submission Open

Keywords: personality disorder; maladaptive personality traits; neurobiology; psychopathy; callous-unemotional traits; impulsivity; dimensional models; aggression; comorbidities; clinical implications

(This special issue belongs to the Section Neuropsychiatry)

Sleep Disorders Affecting Quality of Life: Diagnosis, Symptoms, and Treatment

edited by

Pasquale Tondo

and Giulio Trono

submission deadline 30 Sep 2026 | Viewed by 201 | Submission Open

Keywords: sleep disorders; OSAS; sleep apnea; OSA; CSA; OHS; CPAP

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Cognition and Affective States: Interconnected Dynamics

edited by Sonia Montemurro and

Sara Mondini

submission deadline 30 Sep 2026 | Viewed by 184 | Submission Open

Keywords: mental health; clinical assessment; cognition; psychopathology; clinical neuropsychology

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Molecular Mechanisms of Neurotoxicity and the Discovery of Neuroprotective Agents

edited by

Wayne G. Carter

submission deadline 30 Sep 2026 | Viewed by 129 | Submission Open

Keywords: apoptosis; antioxidants; biomedicines; excitotoxicity; neurotoxicity; neuroprotection; neuroinflammation; phytochemicals; redox stress

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advances in Borderline Personality Disorder: From Detection to Treatment

edited by

Irene Messina

submission deadline 9 Oct 2026 | 1 articles | Viewed by 1479 | Submission Open

Keywords: borderline personality disorder; early detection; treatment; mechanisms; neurobiology

(This special issue belongs to the Section Neuropsychiatry)

Physical Activity Across the Lifespan: Mechanisms, Interventions and Cognitive Function

edited by

Daniele Magistro

and

Simon Cooper

submission deadline 10 Oct 2026 | 1 articles | Viewed by 2280 | Submission Open

Keywords: physical activity; cognitive function; brain health; neuroplasticity; lifespan; intervention; sedentary behaviour; wearable monitoring

(This special issue belongs to the Section Behavioral Neuroscience)

Risks and Mechanisms in Addiction Neuroscience Informing Treatment

edited by Amy A. Herrold

submission deadline 15 Oct 2026 | 2 articles | Viewed by 1946 | Submission Open

Keywords: substance use disorders; risk; mechanism; neuromodulation; psychedelic; GLP-1

(This special issue belongs to the Section Neuropsychiatry)

Advances in the Relationship Among Brain, Physical Function, and Exercise Performance: 2nd Edition

edited by

Luca Petrigna

submission deadline 15 Oct 2026 | Viewed by 189 | Submission Open

Keywords: physical performance; dual task; cognition; sport; environment; cerebellum; movement; neurodegenerative disease

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Language, Communication and the Brain—2nd Edition

edited by

Jayanthi Sasisekaran

submission deadline 20 Oct 2026 | 5 articles | Viewed by 10742 | Submission Open

Keywords: cognitive; attention; working memory; executive functions; linguistic; language planning; speech production; fluency; sensorimotor; hearing; speech and language production; neurotypical; neurodiverse; autism; apraxia; dysarthria; stuttering; speech sound disorders; artificial intelligence; data science; theoretical; data-driven

(This special issue belongs to the Section Neurolinguistics)

Clinical Research on Neurological Rehabilitation After Stroke

edited by

Myoung-Kwon Kim

submission deadline 20 Oct 2026 | 3 articles | Viewed by 9036 | Submission Open

Keywords: stroke rehabilitation; neurological recovery; physical therapy; cognitive rehabilitation; neuroplasticity; functional outcomes; assistive technology; virtual reality therapy; Parkinson’ s disease rehabilitation

(This special issue belongs to the Section Neurorehabilitation)

EEG and fMRI Applications in Exploring Brain Activity

edited by

Nicoletta Cera

and Faustino Ricardo

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2863 | Submission Open

Keywords: fMRI; EEG; resting state; data-driven analysis; machine learning; emotion; cognitive functions; aging; multimodal imaging

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Neural and Cognitive Mechanisms of Tinnitus, Hyperacusis, and Misophonia

edited by

Aazh Hashir

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1180 | Submission Open

Keywords: tinnitus; hyperacusis; misophonia; auditory processing; neuro-otology; peripheral auditory pathology; salience network; predictive processing; sensory gain and gating; stratified mechanisms

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Cognition and the Hearing Brain: Neural Plasticity, Perception and Rehabilitation

edited by Adam S. Greenberg and Michael S. Harris

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: cochlear implants; hearing loss; cognition; cognitive decline/impairment; music perception; speech perception; auditory neuroscience; cognitive neuroscience; hearing rehabilitation

(This special issue belongs to the Section Systems Neuroscience)

Psychological Disorders in Mechanically Ventilated Critical Care Patients: Novel Tools for Diagnosis and Treatment

edited by

Antonio Matías Esquìnas

and

Şengül Kocamer Şahin

submission deadline 20 Oct 2026 | Viewed by 409 | Submission Open

Keywords: mechanical ventilation; psychiatric morbidity; critical care; translational neuroscience; delirium; anxiety; cognitive dysfunction

(This special issue belongs to the Section Neuropsychology)

Noninvasive Neuromodulation Applications in Research and Clinics—2nd Edition

edited by

Mehran Emadi Andani

and

Bernardo Villa-Sánchez

submission deadline 20 Oct 2026 | Viewed by 224 | Submission Open

Keywords: transcranial brain stimulation (TBS); transcranial magnetic stimulation (TMS; rTMS; iTBS; and cTBS); transcranial electrical stimulation (tDCS; tACS; and tRNS); transcranial focused ultrasound stimulation (tFUS); transcranial vagus nerve stimulation (tVNS); virtual reality effect on the brain states; TBS applications in neuromotor disease (Parkinson’ s disease and Huntington’ s disease); TBS applications in mental disease (Alzheimer disease and dementia); TBS application on functional brain mapping (TMS brain mapping); clinical application of brain stimulation in motor symptoms in PD patients (tremor; gait; bradykinesia; postural instability; rigidity; handwriting; etc.); clinical application of brain stimulation in non-motor symptoms (cognitive; psychosis; neuropsychiatric; etc.); safety of brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Neural Mechanisms Underlying Social Cognition and Emotional Processing

edited by

Atiqah Azhari

submission deadline 30 Oct 2026 | 4 articles | Viewed by 10948 | Submission Open

Keywords: social cognition; emotional processing; social neuroscience; developmental neuroscience

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Hypnotherapy: From Basic Research to Clinical Practice

edited by Giuseppe De Benedittis

submission deadline 30 Oct 2026 | 3 articles | Viewed by 4195 | Submission Open

Keywords: hypnosis; brain mechanisms; neuroimaging studies; EEG studies; hypnotherapy; hypnotic analgesia; neurocognitive studies

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Advances in Tourette Syndrome and Tic Disorders: From Mechanism to Intervention

edited by Natalia Szejko

submission deadline 30 Oct 2026 | 1 articles | Viewed by 883 | Submission Open

Keywords: tic disorders; Tourette syndrome; neurodevelopmental mechanisms; neuroimaging; neuromodulation therapy; translational medicine

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neural Control of Feeding Behavior: Focus on Emotional–Metabolic Comorbidity

edited by Patricia de Gortari and Cinthia García-Luna

submission deadline 30 Oct 2026 | Viewed by 247 | Submission Open

Keywords: feeding; mood disorders; anxiety; depression; obesity; anorexia; schizophrenia; neuropeptides; hypothalamus; amygdala; nucleus accumbens

(This special issue belongs to the Section Behavioral Neuroscience)

Gene Therapy for Neurological Diseases

edited by

Sara Marcó

, Miquel García and Xavier Sanchez

submission deadline 30 Oct 2026 | Viewed by 244 | Submission Open

Keywords: gene therapy; neurological diseases; adeno-associated viral vectors; lentiviral vectors; lipid nanoparticles; gene replacement; genome editing; lipid nanoparticles; immune responses; translational neuroscience

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neuromuscular Diseases: Emerging Trends from Molecular Genetics to Multidisciplinary Clinical Practice

edited by Alberto Dubrovsky

submission deadline 30 Oct 2026 | Viewed by 235 | Submission Open

Keywords: neuromuscular; gene therapy; medicine

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Cerebrovascular Diseases and Neuropsychological Sequelae

edited by

Panayiotis Patrikelis

and Themistoklis Papasilekas

submission deadline 30 Oct 2026 | Viewed by 223 | Submission Open

Keywords: cerebrovascular diseases (CVDs); cognitive impairment; neuropsychology; neurorehabilitation; stroke; vascular dementia; brain aneurysms; hypertension

(This special issue belongs to the Section Neuropsychology)

The Role of Multimodal Imaging in Assessing the Biology and Staging of Neurodegenerative Disorders

edited by

Andrea Varrone

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2525 | Submission Open

Keywords: amyloid beta; phosphorylated tau; alpha-synuclein; neuronal loss; neuromelanin; iron content; cardiac denervation; dopaminergic cell loss

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Assessment and Training of Perceptual-Motor Performance (2nd Edition)

edited by

Gary Wilkerson

and

Scott L. Bruce

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2273 | Submission Open

Keywords: perception; cognition; motor control; neural efficiency; traumatic brain injury; neurodegeneration; psycho-affective disorder

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neural Mechanisms and Treatments of Pain

edited by Mayank Gupta

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1973 | Submission Open

Keywords: mild traumatic brain injury; neural mechanisms of mild traumatic brain injury; prognostic factors; diagnostic criteria; treatment of chronic mild traumatic brain injury

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advanced Applications of Non-Invasive Stimulation for Therapeutics

edited by Naaz Desai, Robert Chen and Amitabh Bhattacharya

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1119 | Submission Open

Keywords: non-invasive neuromodulation; brain stimulation; spinal and peripheral stimulation; transcranial magnetic stimulation; focused ultrasound stimulation; transcranial electrical stimulation; neuroplasticity; translational therapeutics; brain disorders

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Child and Adolescent Psychiatry: Developmental Perspectives, Psychopathology, and Clinical Care

edited by M. Giulia D'Acunto

submission deadline 31 Oct 2026 | 1 articles | Viewed by 488 | Submission Open

Keywords: child and adolescent psychiatry; developmental psychopathology; emotional dysregulation; mood and anxiety disorders; psychosis; suicidality; neurodevelopmental disorders; non-suicidal self-injury; internet use disorders

(This special issue belongs to the Section Neuropsychology)

Pharmacological and Psychopathological Clinical Studies on Psychotic and Mood Disorders

edited by Matteo Lupi and Alessandro Carano

submission deadline 31 Oct 2026 | 1 articles | Viewed by 473 | Submission Open

Keywords: clinical pharmacology; psychopharmacology; psychopathology; phenomenology; psychosis; mood disorders

(This special issue belongs to the Section Neuropsychiatry)

Mental Disorders: Diagnosis, Symptoms, Assessment, and Treatment

edited by Donatella Marazziti

submission deadline 31 Oct 2026 | 1 articles | Viewed by 382 | Submission Open

Keywords: mental disorders; clinical diagnosis; psychopathological assessment; evidence-based treatment; transdiagnostic processes; comorbidity; psychometric validation; translational mental health research

(This special issue belongs to the Section Neuropsychiatry)

Multimodal Neuroimaging and Precision Management in Neurodegenerative Diseases

edited by

Rodolfo Gabriel Gatto

submission deadline 31 Oct 2026 | Viewed by 222 | Submission Open

Keywords: neuroimaging technologies; precision management; neurodegenerative disease; molecular biomarkers; translational neuroscience

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

The Evolving Landscape of Trigeminal Neuralgia: From Bench to Bedside and Beyond

edited by

Andreas Demetriades

and Fuminari Komatsu

submission deadline 1 Nov 2026 | Viewed by 343 | Submission Open

Keywords: trigeminal neuralgia; facial pain syndromes; neurovascular conflict; central sensitization; channelopathies; predictive biomarkers; pharmacotherapy; neuropsychiatric comorbidities; patient-reported outcomes; comparative effectiveness of surgical modalities; microvascular decompression; stereotactic radiosurgery; percutaneous procedures; glycerol rhizolysis; percutaneous ballonn compression; radiofrequency thermocoagulation; comparative effectiveness of surgical modalities

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Dementia and Cognitive Decline in Aging

edited by

Yvonne Leung

submission deadline 5 Nov 2026 | 3 articles | Viewed by 3532 | Submission Open

Keywords: dementia; cognitive impairment; Alzheimer’ s disease; mild cognitive impairment (MCI); neurodegeneration; cognitive aging; biomarkers; cognitive resilience; cognitive reserve

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by

Nicoletta Ciccarelli

and

Elisa Pini

submission deadline 10 Nov 2026 | 3 articles | Viewed by 6388 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Advanced Study in Stroke and Stroke Rehabilitation

edited by