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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Speech and Language Research for Cognitive Well-Being in Aging

edited by

Maria Teresa Carthery-Goulart

, Lilian Cristine Hubner and Erica Dos Santos Rodrigues

submission deadline 10 Jul 2026 | 6 articles | Viewed by 23156 | Submission Open

Keywords: communication skills; language abilities; speech; cognitive function; neurodegenerative diseases; neuromodulation

(This special issue belongs to the Section Neurolinguistics)

Cognitive Processes in Human–AI Interaction: Neural and Behavioral Insights

edited by

Gioele Gavazzi

submission deadline 10 Jul 2026 | 1 articles | Viewed by 867 | Submission Open

Keywords: cognitive control; human–artificial intelligence interaction; inhibition & AI

(This special issue belongs to the Section Behavioral Neuroscience)

Mental Health and Justice: New Advances in Forensic Psychiatry

edited by

Andrea Cioffi

submission deadline 14 Jul 2026 | Viewed by 713 | Submission Open

Keywords: forensic psychiatry; legal medicine; ethics and mental health; psychiatry in correctional settings; criminal responsibility; expert witness; risk assessment; violent behavior; psychiatrist’s professional liability

(This special issue belongs to the Section Neuropsychiatry)

Primary Progressive Aphasia: What Happens to Speech and Language? What Can We Do to Help?

edited by

Monica Lavoie

, Anna Volkmer, Jason D. Warren and

Petronilla Battista

submission deadline 15 Jul 2026 | 9 articles | Viewed by 11217 | Submission Open

Keywords: primary progressive aphasia; language; brain; communication; cognition

(This special issue belongs to the Section Neurolinguistics)

Sleep Disorders: Bridging Basic Mechanisms and Clinical Translation

edited by

Oscar Arias-Carrión

submission deadline 15 Jul 2026 | 1 articles | Viewed by 1542 | Submission Open

Keywords: sleep disorders; insomnia; narcolepsy; REM sleep behaviour disorder; obstructive sleep apnoea; hypersomnia; circadian rhythms; biomarkers; neuroimaging; translational neuroscience

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

The Influence of Genetic/Environmental Risk Factors on Early Brain Development

edited by Duy Phan

submission deadline 15 Jul 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: neurodevelopmental disorders; human genomics; whole-exome sequencing; whole-genome sequencing; neonatal neurology; epilepsy; seizures; congenital malformations

(This special issue belongs to the Section Systems Neuroscience)

Translating Gut–Brain Crosstalk into Novel Neurological Treatments

edited by

Diego Iacono

submission deadline 15 Jul 2026 | Viewed by 285 | Submission Open

Keywords: gut–brain axis; central nervous system; enteric nervous system; anatomy; microbiota; GI-to-brain signals; brain-to-GI signals; neuroinflammation

(This special issue belongs to the Section Systems Neuroscience)

At the Frontiers of Neurorehabilitation: 3rd Edition

edited by

Manuel Gaviria

submission deadline 17 Jul 2026 | 8 articles | Viewed by 13674 | Submission Open

Keywords: CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; optimization of clinical care; motor learning; cognitive reinforcement; motivational issues; relevant outcome measures; innovative approaches; rehabilitation devices; neuro-prosthetics; brain–computer interfaces; clinical trials for validation; regulatory issues; activities of daily living (ADLs) autonomy; quality of life; neurodevelopmental disorder

(This special issue belongs to the Section Neurorehabilitation)

Advances in Emotion Processing and Cognitive Neuropsychology

edited by

Pasquale La Malva

submission deadline 20 Jul 2026 | 11 articles | Viewed by 21254 | Submission Open

Keywords: emotion processing; cognitive neuropsychology; affective neuroscience; emotion regulation; executive functions; neuroimaging (fMRI, EEG); non-invasive brain stimulation (TMS, tDCS); psychophysiological measures; age-related differences; translational research

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Cerebrospinal Fluid Dynamics in Brain Health and Disease

edited by

Renan B. Domingues

submission deadline 20 Jul 2026 | Viewed by 351 | Submission Open

Keywords: cerebrospinal fluid; glymphatic system; intracranial pressure; idiopathic intracranial hypertension; normal pressure hydrocephalus; neuroinflammation; neuroinfection; neurodegeneration; biomarkers; brain clearance

(This special issue belongs to the Section Systems Neuroscience)

The Impact of Social Media on Human Behavior and Mental Health

edited by

Ebenezer Larnyo

and Henry Asante Antwi

submission deadline 23 Jul 2026 | Viewed by 864 | Submission Open

Keywords: social media; mental health; human behavior; psychological well-being; digital addiction; cognitive impairment; online communities; public health; health behavior change; algorithmic bias

(This special issue belongs to the Section Neuropsychology)

Chronic Non-Infectious Diseases with a High Impact on the Central Nervous System

edited by

Grazyna Lietzau

submission deadline 24 Jul 2026 | 6 articles | Viewed by 26788 | Submission Open

Keywords: mental disorders; metabolic diseases; migraine; movement disorders; multiple sclerosis; neurodegenerative diseases; stroke

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advancements in Diagnosis and Treatment of Stroke and Cerebral Aneurysms: A Call for Innovative Research Submissions

edited by

Sherief Ghozy

, Ram Kadirvel and Ajay Malhotra

submission deadline 24 Jul 2026 | 9 articles | Viewed by 20225 | Submission Open

Keywords: stroke; cerebral aneurysms; minimally invasive surgical; imaging; neurovascular

(This special issue belongs to the Section Neurorehabilitation)

Chemotherapy-Associated Brain Damage—Translational Insights from Pre-Clinical and Clinical Research

edited by

Nikola Stojanović

submission deadline 25 Jul 2026 | Viewed by 353 | Submission Open

Keywords: chemotherapeutics; brain damage; brain fog; translation studies; preventing brain damage

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advances in Theory and Applications in Geriatric Musculoskeletal and Neurological Therapy

edited by Anna Christakou

submission deadline 25 Jul 2026 | Viewed by 318 | Submission Open

Keywords: myopathy; dementia; geriatric medicine; geriatric physiotherapy; osteoporosis; falls; arthritis; muscle weakness; shoulder dysfunction; rehabilitation

(This special issue belongs to the Section Systems Neuroscience)

Artificial Intelligence in Neurological Disorders

edited by

Rahul Kashyap

and

Pallavi Dinesh Shirsat

submission deadline 30 Jul 2026 | 3 articles | Viewed by 4210 | Submission Open

Keywords: artificial intelligence; neurological disorders; machine learning; deep learning; neuroimaging; Alzheimer’s disease; Parkinson’s disease; predictive analytics; personalized medicine; ethical AI

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Bilateral Motor Learning, Sensorimotor Adaptation, and Neuromodulation

edited by

Jinsung Wang

and

Yuming Lei

submission deadline 30 Jul 2026 | 1 articles | Viewed by 1121 | Submission Open

Keywords: interlimb transfer; intermanual transfer; bilateral transfer; cross-education; sensorimotor learning; generalization of motor learning; motor adaptation; motor memory; motor control; skill acquisition; neuroplasticity; bilateral coordination; rehabilitation; stroke rehabilitation; neurorehabilitation; visuomotor adaptation; locomotor adaptation; neuroplasticity; brain stimulation; aging; computational neuroscience

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Decoding Motor Control: Multimodal Approaches to Cortical Plasticity and Learning

edited by

Gonzalo Marquez

and

David Colomer-Poveda

submission deadline 30 Jul 2026 | Viewed by 299 | Submission Open

Keywords: motor control; cortical plasticity; motor learning; multimodal approaches; neurorehabilitation; brain–machine interfaces; computational neuroscience; neuroimaging; electrophysiology; biomechanics

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Applications of Neuroimaging in Healthy Aging and Neurodegenerative Diseases

edited by Samaneh Nemati

submission deadline 30 Jul 2026 | Viewed by 228 | Submission Open

Keywords: neuroimaging; healthy aging; neurodegenerative disorders; cognitive aging; multimodal imaging; network neuroscience; functional connectivity; structural connectivity; machine learning; biomarkers

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI

edited by

Dionysios Tafiadis

, Nafsika Ziavra,

Angelos Papadopoulos

and

Konstantinos Drosos

submission deadline 31 Jul 2026 | 6 articles | Viewed by 9733 | Submission Open

Keywords: lifespan speech and language disorders; lifespan communication disorders; special learning disabilities; lifespan voice and swallowing disorders; assessment; intervention; innovations; neuromodulation; artificial intelligence

(This special issue belongs to the Section Neurolinguistics)

Diagnosis and Treatment of Post-Stroke and Progressive Aphasias

edited by Sigfus Kristinsson and Sladjana Lukic

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4151 | Submission Open

Keywords: post-stroke aphasia; primary progressive aphasia; lesion–symptom mapping; neuroimaging; speech and language treatment; neural markers

(This special issue belongs to the Section Neurolinguistics)

Biobehavioral Neuroscience and Pain Medicine: Assessment and Management of Pain

edited by

Raúl Ferrer-Peña

and

Francisco Gurdiel-Álvarez

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2926 | Submission Open

Keywords: biobehavioral neuroscience; chronic pain; pain modulation; emotion and motor control; brain plasticity; pain assessment; neurobehavioral markers; central sensitization; behavioral interventions; translational pain research

(This special issue belongs to the Section Behavioral Neuroscience)

Electrophysiological Approaches to Cognitive Neuroscience

edited by

Andrés Antonio González Garrido

and

Steven Woltering

submission deadline 31 Jul 2026 | 3 articles | Viewed by 1707 | Submission Open

Keywords: electroencephalography (EEG); cognition, neurocognitive processes; brain dynamics; cognitive neuroscience; event-related potentials (ERP); functional connectivity; neural oscillations; multimodal neuroimaging; clinical EEG

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Deep Brain Stimulation (DBS)—Current Status and Future Directions

edited by Yousef Salimpour

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1174 | Submission Open

Keywords: deep brain stimulation; neuromodulation; adaptive closed-loop systems; directional leads; neural biomarkers artificial intelligence; personalization treatment; biocompatible materials

(This special issue belongs to the Section Neurodegenerative Diseases)

From Neural Mechanisms to Plasticity-Driven Therapies: A Focus on Auditory Processing

edited by Giulia Cartocci,

Bianca Maria Serena Inguscio

Dario Rossi

and Saviana Antonella Barbati

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1000 | Submission Open

Keywords: neuroplasticity; sensory deprivation; hearing loss; cochlear implants; hearing aids; sensory disorders

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Substance Use and Addiction: From Molecular Mechanisms to Treatment

edited by

Davide Arillotta

Giuseppe Floresta

and

Fabrizio Schifano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 752 | Submission Open

Keywords: substance use disorders; addiction; reward; neuroplasticity; craving; precision medicine; translational neuroscience; co-occurring substance use and mental disorders

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Applications of Cognitive Behavioral Therapy in Mental Disorders

edited by Maria Rita Sergi

submission deadline 31 Jul 2026 | Viewed by 738 | Submission Open

Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions

Basic Mechanisms of Speech Production, Speech Perception and Perception-Production Link

edited by Yi Xu and

Anqi Xu

submission deadline 31 Jul 2026 | Viewed by 365 | Submission Open

Keywords: speech production; speech perception; production-perception link; articulatory dynamics; sensorimotor learning; speech acquisition; vocal learning; perceptual learning; computational modelling; modelling simulation

(This special issue belongs to the Section Neurolinguistics)

Human-Centered Robotics Applications in Rehabilitation of Individuals with Neurological Conditions

edited by Giovanni Morone

submission deadline 31 Jul 2026 | Viewed by 360 | Submission Open

Keywords: robotics; neurological disabilities; stroke; gait; rehabilitation

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

The Intersection of Mind and Muscle: Motor Control and Psychology

edited by

Wanxiang Yao

and Guang Yue

submission deadline 31 Jul 2026 | Viewed by 315 | Submission Open

Keywords: motor control; motor learning cognition; neurophysiology; psychophysiology; neuroimaging; mind–body interaction

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Targeted Therapy of Glioma: Current Developments in Targeted Drug Delivery Systems

edited by Łukasz Uram

submission deadline 31 Jul 2026 | Viewed by 274 | Submission Open

Keywords: glioblastoma multiforme therapy; targeted glioma therapy; in vivo and in vitro studies; blood–brain barrier crossing; repurposing drugs; nanoparticles as targeting factors

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovative Research on the Health, Physiological and Neuroscientific Consequences of Mental Health Conditions

edited by

Jeffrey L. Kibler

submission deadline 31 Jul 2026 | Viewed by 244 | Submission Open

Keywords: health risks; psychophysiological; neuroscience; mental health

(This special issue belongs to the Section Neuropsychology)

Chronic Pain: Symptoms, Causes, Real World Evidence, and Diagnosis

edited by Guy Hans

submission deadline 1 Aug 2026 | 1 articles | Viewed by 1256 | Submission Open

Keywords: neuropathic pain; visceral pain; nociplastic pain; pharmacology of pain; invasive pain therapies; multidisciplinary approach; real-world evidence; pre-emptive analgesia; diagnostic evaluation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neuroimaging Biomarkers for the Diagnosis of Mental Disorders

edited by

Fabrício Pereira

submission deadline 10 Aug 2026 | Viewed by 543 | Submission Open

Keywords: neuroimaging biomarkers; multimodality imaging; precision psychiatry; translational neuropsychiatric research; neuroimaging-informed phenotype; personalized mental health; computer-aided diagnosis; artificial intelligence in psychiatry; imaging-based prognosis

(This special issue belongs to the Section Neuropsychiatry)

Neuroimmunology: Past, Present, and Promise

edited by

Maria Elsa Gambuzza

submission deadline 10 Aug 2026 | Viewed by 249 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative disorders; multiple sclerosis; neurological disorders; neuropsychiatric disorders; peripheral nervous system; neuro-oncological conditions

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Aug 2026 | 5 articles | Viewed by 6808 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Non-Invasive Neurotechnologies for Cognitive Augmentation

edited by

Caterina Cinel

Davide Valeriani

and

Saugat Bhattacharyya

submission deadline 15 Aug 2026 | 2 articles | Viewed by 2447 | Submission Open

Keywords: neurotechnology; brain–computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Advances in Parkinson’s Disease

edited by

Osmar Pinto Neto

submission deadline 15 Aug 2026 | Viewed by 356 | Submission Open

Keywords: Parkinson’s disease; neurodegeneration; motor control; digital biomarkers; sensorimotor integration; neuromuscular physiology; machine learning and signal analysis; early diagnosis; neuromodulation; translational neuroscience

(This special issue belongs to the Section Neurodegenerative Diseases)

Bridging Neurodegeneration and Neuroinflammation: Novel Therapeutic Approaches

edited by

Maheedhar Kodali

submission deadline 15 Aug 2026 | Viewed by 325 | Submission Open

Keywords: neurodegeneration; neuroinflammation; transcriptomic alterations; extracellular vesicles; mTOR signaling; autophagy and mitophagy; synaptogenesis brain repair preclinical models; therapeutic interventions

(This special issue belongs to the Section Neurodegenerative Diseases)

Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia

edited by Chiara Baglioni and Debora Meneo

submission deadline 20 Aug 2026 | 3 articles | Viewed by 7602 | Submission Open

Keywords: sleep health; insomnia; emotional processes; pre-sleep behaviours; cognitive processes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neurosurgery: Minimally Invasive Surgery in Brain and Spine—2nd Edition

edited by Christopher Ahuja

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1170 | Submission Open

Keywords: minimally invasive surgery; neurosurgery; brain; spine

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Writing on the Brain: Current Trends, Challenges and Future Venues

edited by Roberto Limongi

submission deadline 20 Aug 2026 | Viewed by 459 | Submission Open

Keywords: writing and the brain; writing to learn; epistemic writing; expressive writing; memory and writing

(This special issue belongs to the Section Neurolinguistics)

Defining Emotion: A Collection of Current Models

edited by

Peter Walla

submission deadline 21 Aug 2026 | 9 articles | Viewed by 32044 | Submission Open

Keywords: emotion; affect; affection; affective processing of feelings; mood; cognitive processing

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroeducation: Bridging Cognitive Science and Classroom Practice

edited by Yuvaraj Rajamanickam

submission deadline 25 Aug 2026 | 3 articles | Viewed by 13102 | Submission Open

Keywords: education; neuroscience; learning and memory; neurodevelopmental disorders; emotions; cognitive skills; neuroplasticity; EEG; neuroimaging; school; classroom; educational interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroprotection for Neurodegenerative Diseases: Current Status and Future Perspectives

edited by

Adriano Martimbianco de Assis

submission deadline 25 Aug 2026 | Viewed by 416 | Submission Open

Keywords: neuroprotection; neurodegeneration; Alzheimer’s disease; Parkinson’s disease; amyotrophic lateral sclerosis (ALS); biomarkers; neuroinflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neurodegenerative Diseases)

Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders

edited by

Alexandra Susana Latini

and Ana Lucia De Paul

submission deadline 28 Aug 2026 | 4 articles | Viewed by 6069 | Submission Open

Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovations in Skull Base Surgery

edited by

Fumihiro Matano

submission deadline 29 Aug 2026 | 1 articles | Viewed by 2045 | Submission Open

Keywords: microsurgery; endoscopic skull base surgery; exoscopic surgery; minimally invasive neurosurgery; skull base and cerebrovascular surgery; intracranial aneurysm; moyamoya disease; RNF213

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Predictive Processing in Brain and Behavior

edited by Mario Trevino

submission deadline 30 Aug 2026 | 2 articles | Viewed by 2491 | Submission Open

Keywords: predictive processing; sensorimotor integration; visuomotor coordination; prediction error; adaptive behavior; anticipatory gaze; motor learning; neural dynamics

(This special issue belongs to the Section Behavioral Neuroscience)

Exploring Human Emotion: From Brain to Behavior Across Disciplines

edited by

Simona Massimino

and

Carmelo M. Vicario

submission deadline 30 Aug 2026 | Viewed by 357 | Submission Open

Keywords: emotion; perception; cognition; neural process

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Outcome Measures in Rehabilitation

edited by

Antonio Nardone

and

Irene Aprile

submission deadline 31 Aug 2026 | 8 articles | Viewed by 10649 | Submission Open

Keywords: outcome measures; qualitative measures; quantitative measures; neurologic rehabilitation; musculoskeletal rehabilitation; cardiopulmonary rehabilitation; robotic rehabilitation; movement analysis; gait analysis

(This special issue belongs to the Section Neurorehabilitation)

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