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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Sensory Function and Perception in Dementia

edited by

Andrea Tales

submission deadline 5 May 2025 | 1 articles | Viewed by 1644 | Submission Open

Keywords: ageing ; cognitive decline ; objectively measured effects of sensory dysfunction in people with cognitive decline ; subjective reports of sensory dysfunction in people with cognitive decline

(This special issue belongs to the Section Neurodegenerative Diseases)

The Latest Research on Drug Treatment of Epilepsy

edited by Alberto E. Musto and Luis Pacheco

submission deadline 5 May 2025 | Viewed by 185 | Submission Open

Keywords: epilepsy; neuroinflammation; seizures; cannabinoid

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Stress, Resilience and Susceptibility

edited by Elaine Gavioli

submission deadline 15 May 2025 | 3 articles | Viewed by 3378 | Submission Open

Keywords: stress; resilience; vulnerability; psychiatric disorders; biomarkers

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 May 2025 | Viewed by 407 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Molecular and Cellular Biology of Brain Tumors and Neuro-Oncology

edited by Rafael Roesler

submission deadline 16 May 2025 | 1 articles | Viewed by 1706 | Submission Open

Keywords: glioma; medulloblastoma; ependymoma; brain cancer; central nervous system tumor; neuro-oncology

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Current Perspectives on the Management of Acute-Phase Ischemic Stroke

edited by Stefano Caproni, Ettore Nicolini and Soffien Ajmi

submission deadline 16 May 2025 | 1 articles | Viewed by 740 | Submission Open

Keywords: acute ischemic stroke; endovascular thrombectomy; thrombolysis; clinical treatment

(This special issue belongs to the Section Neurorehabilitation)

The Application of EEG in Neurorehabilitation

edited by

Ryouhei Ishii

submission deadline 19 May 2025 | 9 articles | Viewed by 8016 | Submission Open

Keywords: electroencephalography (EEG); neurorehabilitation; neural plasticity; personalized treat-ment strategies; brain– computer interfaces

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

So, What? What Does Contemporary ADHD Research Tell Us about Lived Experiences?

edited by

Conor Mc Guckin

, Kate Carr-Fanning and Aoife Lynam

submission deadline 19 May 2025 | 1 articles | Viewed by 1508 | Submission Open

Keywords: ADHD; social model; participant voice; educational inclusion; social inclusion; transition planning; family experience; early intervention; policy; advocacy

(This special issue belongs to the Section Developmental Neuroscience)

Advances in the Pharmacologic Treatment of Depression, Anxiety, and Other Psychiatric Disorders

edited by Danielle S. Cha

submission deadline 20 May 2025 | Viewed by 195 | Submission Open

Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease

(This special issue belongs to the Section Neuropsychiatry)

Mechanisms That Support Music Learning and Development

edited by Jennifer A. Bugos

submission deadline 20 May 2025 | Viewed by 135 | Submission Open

Keywords: music; music therapy; neurophysiological research; cognitive development; music cognition; performance; auditory processing

(This special issue belongs to the Section Behavioral Neuroscience)

Neuromodulation and Neurostimulation in Psychiatric Disorders

edited by

Takuma Inagawa

submission deadline 25 May 2025 | 2 articles | Viewed by 2812 | Submission Open

Keywords: brain stimulation; rTMS; ECT; depression; OCD

(This special issue belongs to the Section Neuropsychiatry)

Anosognosia and the Determinants of Self-Awareness

edited by

Guido Gainotti

submission deadline 25 May 2025 | 1 articles | Viewed by 759 | Submission Open

Keywords: anosognosia; disease unawareness; stroke patients; Alzheimer’ s disease; self-awareness; hemiplegia; unilateral neglect; Anton syndrome; insight

(This special issue belongs to the Section Neuropsychology)

Genetics of Neurodegenerative Diseases: Retrospect and Prospect

edited by

Kallirhoe Kalinderi

and

Vasileios T. Papaliagkas

submission deadline 30 May 2025 | 2 articles | Viewed by 4102 | Submission Open

Keywords: Alzheimer's disease (AD); Parkinson's disease (PD); amyotrophic lateral sclerosis (ALS); multiple sclerosis; neurodegeneration; protein aggregation; therapy; pharmacogenetics; gene; nutrigenomics

(This special issue belongs to the Section Neurodegenerative Diseases)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 30 May 2025 | 2 articles | Viewed by 3898 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Novel Neuroimaging of Neurological and Psychiatric Disorders

edited by

Darrin J. Lee

submission deadline 30 May 2025 | Viewed by 213 | Submission Open

Keywords: neuroimaging; diagnosis; treatment; psychiatric diseases; brain structure

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 30 May 2025 | Viewed by 171 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Diagnosis, Therapy and Rehabilitation in Neuromuscular Diseases

edited by

Vincenzo Donadio

submission deadline 31 May 2025 | 7 articles | Viewed by 16667 | Submission Open

Keywords: neuromuscular diseases; autonomic dysfunctions; pain; small fiber neuropathies; Fabry disease; hereditary transthyretin amyloidosis; myasthenic disorders; myopathies; diagnosis and treatment

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Aging-Related Changes in Memory and Cognition

edited by Anna Christakou

submission deadline 31 May 2025 | 7 articles | Viewed by 6280 | Submission Open

Keywords: aging; quality of life; cognitive/physical health; neurodegenerative diseases; geriatric physiotherapy; memory; cognition; attention; prevention; therapeutic treatments

(This special issue belongs to the Section Neurodegenerative Diseases)

Brain Tumors: From Molecular Basis to Therapy

edited by Paolo Tini and Giuseppe Minniti

submission deadline 31 May 2025 | 4 articles | Viewed by 4293 | Submission Open

Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance

(This special issue belongs to the Section Neuro-oncology)

Relationships Between Disordered Sleep and Mental Health

edited by Anne M. Fink

submission deadline 31 May 2025 | 2 articles | Viewed by 3413 | Submission Open

Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide

(This special issue belongs to the Section Neuropsychiatry)

Brain Stimulation Treatments for Memory Disorders

edited by

Windy McNerney

and

John Philip Coetzee

submission deadline 31 May 2025 | 1 articles | Viewed by 1259 | Submission Open

Keywords: DBS; tACS; tDCS; TUS; memory loss; plasticity; cognition; biochemistry

(This special issue belongs to the Section Systems Neuroscience)

The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System

edited by Kyle Gobrogge

submission deadline 1 Jun 2025 | 1 articles | Viewed by 1181 | Submission Open

Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

State of the Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes

edited by Jeannette R. Mahoney

submission deadline 1 Jun 2025 | 1 articles | Viewed by 1002 | Submission Open

Keywords: multisensory integration; sensorimotor integration; aging; mobility; balance; falls; cognition; dementia

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Use of Chemogenetics and Optogenetics on Understanding the Neurobiology of Brain Disorders

edited by

Sandesh Panthi

and

Marc Ekker

submission deadline 6 Jun 2025 | Viewed by 663 | Submission Open

Keywords: chemogenetics; optogenetics; DREADDs; brain disorders; neurobiology of disease

From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition

edited by

Daniele Corbo

submission deadline 10 Jun 2025 | 3 articles | Viewed by 4592 | Submission Open

Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Current Research in Neurosurgery

edited by

Roberto Altieri

, Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque

submission deadline 10 Jun 2025 | 4 articles | Viewed by 3267 | Submission Open

Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 10 Jun 2025 | Viewed by 301 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 13 Jun 2025 | 5 articles | Viewed by 9002 | Submission Open

Keywords: neuroinflammation; oxidative stress; mitochondrial dysfunction; metabolism; metabolomics; neurodegenerative diseases; neurodevelopmental diseases; pharmacological targets; potential drugs

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Mental Health: From a Neurobiology Perspective

edited by

Zuleide Maria Ignácio

and

Margarete Dulce Bagatini

submission deadline 13 Jun 2025 | 2 articles | Viewed by 4719 | Submission Open

Keywords: neurobiology; mental health; psychiatric disorders; neurotransmission; signaling pathway; genetic and epigenetic factors; neurodevelopment; inflammation; therapeutic interventions; translational and clinical research

(This special issue belongs to the Section Neuropsychiatry)

Exploration of the Brain Structural Changes in Patients with Mental Illness

edited by

Fengyu Zhang

submission deadline 15 Jun 2025 | Viewed by 279 | Submission Open

Keywords: psychiatric diseases; human brain connectome; biomarkers; endophenotypes

(This special issue belongs to the Section Neuropsychiatry)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Jun 2025 | Viewed by 180 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

New Challenges in the Study of Cognitive Impairment in Parkinson’s Disease

edited by

Sonia Di Tella

and Laura Colautti

submission deadline 16 Jun 2025 | 2 articles | Viewed by 3631 | Submission Open

Keywords: Parkinson’ s disease; cognitive impairment; assessment; intervention; executive functions; learning; decision making; creativity; cognitive reserve

(This special issue belongs to the Section Neurodegenerative Diseases)

Prediction and Prevention of Psychotic Disorders

edited by Francesco Monaco and Annarita Vignapiano

submission deadline 20 Jun 2025 | 1 articles | Viewed by 2458 | Submission Open

Keywords: psychotic disorders; early identification; prevention; biomarkers; genetics; psychosocial interventions

(This special issue belongs to the Section Neuropsychiatry)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by

Nicoletta Ciccarelli

submission deadline 20 Jun 2025 | 1 articles | Viewed by 618 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Neurofunctional Basis of Language Processing—2nd Edition

edited by

Roozbeh Rezaie

and

Vahab Youssof Zadeh

submission deadline 20 Jun 2025 | Viewed by 206 | Submission Open

Keywords: language neurological disorders; non-invasive; brain mapping; neural networks; plasticity

(This special issue belongs to the Section Neurolinguistics)

Neurosurgery: Minimally Invasive Surgery in Brain and Spine

edited by Christopher Ahuja

submission deadline 25 Jun 2025 | 1 articles | Viewed by 1054 | Submission Open

Keywords: minimally invasive surgery; neurosurgery; brain; spine

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Multisensory Perception of the Body and Its Movement

edited by Monica Gori, Lara Coelho and Silvia Zanchi

submission deadline 27 Jun 2025 | 3 articles | Viewed by 3277 | Submission Open

Keywords: body; space; spatial navigation; development; blindness multisensory

(This special issue belongs to the Section Sensory and Motor Neuroscience)

What Impact Does Lack of Sleep Have on Mental Health?

edited by

Haitham Jahrami

Seithikurippu R. Pandi-Perumal

and

Khaled Trabelsi

submission deadline 28 Jun 2025 | 2 articles | Viewed by 5239 | Submission Open

Keywords: ADHD; Alzheimer's; anxiety; autism; bipolar disorder; CBT-I; chronotherapy; circadian rhythm; cognitive function; depression; eating disorders; emotional regulation; epilepsy; executive function; insomnia; jet lag; memory consolidation; mental health; multiple sclerosis; neurobiological mechanisms; neurodevelopmental disorders; neuropsychiatric disorders; OCD; Parkinson's disease; personality disorders; PTSD; schizophrenia; self-harm; shift work; sleep deprivation; sleep disturbances; sleep quality; social cognition; substance use disorders; suicidal ideation; wearable technology

(This special issue belongs to the Section Neuropsychiatry)

Integrating Advanced Imaging Techniques and Computational Models in Headache Research

edited by Catherine S. Hubbard

submission deadline 28 Jun 2025 | Viewed by 118 | Submission Open

Keywords: personalized medicine; migraine; headache disorders; machine learning; deep learning; neuroimaging; animal models; neuromodulation; fMRI; neural networks

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life

edited by

Giuseppe Barbato

submission deadline 30 Jun 2025 | 5 articles | Viewed by 6675 | Submission Open

Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

New Advances in Neuroimmunology and Neuroinflammation

edited by

Junhui Wang

Xueping Chen

, Jing Sun and Matheus Uba Chupel

submission deadline 30 Jun 2025 | 6 articles | Viewed by 6467 | Submission Open

Keywords: neuroinflammation; neuroimmunology; glia; neurodegenerative diseases; cytokines; chemokines

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

New Advances in the Development of New Drugs and Treatment Targets for Brain Cancers (2nd Edition)

edited by

Luis Ibarra

Laura Natalia Milla Sanabria

and

Nuria Arias-Ramos

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2394 | Submission Open

Keywords: gliomas; targeted therapy; blood– brain barrier; tumor microenvironment; molecular and cellular biology

(This special issue belongs to the Section Neuro-oncology)

Clinical Research on Sleep Disorders: Opportunities and Challenges

edited by

Pasquale Tondo

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2303 | Submission Open

Keywords: innovation; personalized management; sleep disorders; telemonitoring; treatment

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Recent Advances in Neuroscience: Theoretical, Applied, and Experimental Research

edited by

Julian Keenan

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1975 | Submission Open

Keywords: neuroscience; genetics; brain; optogenetics; fMRI; MRI; TMS; tDCS; gene therapy; evolutionary neuroscience; psychiatric disorders

(This special issue belongs to the Section Systems Neuroscience)

Minimally Invasive Surgery for Brain and Skull Base Tumors

edited by

Carmine Antonio Donofrio

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1499 | Submission Open

Keywords: minimally invasive surgery; keyhole approaches; endoscopic surgery; stereotactic surgery; parafascicular surgery; brain tumors; neuro-oncology; skull base tumors

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Spinal Cord Injury

edited by Mark H. Tuszynski and Paul Lu

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1301 | Submission Open

Keywords: spinal cord injury; axonal regeneration; neural stem cells; neural progenitor cells; synaptic connection; neuronal relay

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neural Correlates of Art and Multisensory Perception

edited by

Letizia Palumbo

Zaira Cattaneo

and