Special Issues

Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Therapeutic Approaches for Treatment-Resistant Depression
edited by Yuliya O. Knyahnytska
submission deadline 30 Nov 2025 | Viewed by 149 | Submission Open
Keywords: treatment resistant depression; hard-to-treat mood disorders; innovative interventions; therapeutic brain stimulation interventions; neuromodulation interventions; novel psychotropics
(This special issue belongs to the Section Neuropsychiatry)
Chronic Non-Infectious Diseases with a High Impact on the Central Nervous System
edited by
submission deadline 5 Dec 2025 | 6 articles | Viewed by 11931 | Submission Open
Keywords: mental disorders; metabolic diseases; migraine; movement disorders; multiple sclerosis; neurodegenerative diseases; stroke
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Advances in Cognitive and Psychometric Evaluation submission deadline 10 Dec 2025 | 3 articles | Viewed by 2628 | Submission Open
Keywords: cognitive assessment; psychometric evaluation; measurement innovation; advanced data analysis; affective assessment
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Pharmacy and Mental Health
edited by
submission deadline 10 Dec 2025 | 1 articles | Viewed by 1205 | Submission Open
Keywords: pharmacy; mental health; pharmacists
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Interoception and Women’s Health
edited by and Jennifer Murphy
submission deadline 12 Dec 2025 | 2 articles | Viewed by 20454 | Submission Open
Keywords: interoception; women’ s health; sex differences; healthcare disparities; reproductive health
(This special issue belongs to the Section Neuropsychology)
The Use of Robotics and Artificial Intelligence in Neurorehabilitation: From Diagnosis to Treatment submission deadline 15 Dec 2025 | 5 articles | Viewed by 16701 | Submission Open
Keywords: robotic-assisted rehabilitation; machine learning; neurological disorders; artificial intelligence
(This special issue belongs to the Section Neurorehabilitation)
Neuromodulation for Pain Management: Evidence of Safety and Efficacy
edited by and Rafael Tomás Andújar-Barroso
submission deadline 15 Dec 2025 | 5 articles | Viewed by 8085 | Submission Open
Keywords: chronic pain; clinical neurostimulation; invasive neuromodulation; neurostimulation-induced plasticity; non-invasive neuromodulation; pain management; transcranial electric stimulation; transcranial magnetic stimulation
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Machine Learning and Artificial Intelligence Algorithms in Neuroscience
edited by Mohsen Ahmadi
submission deadline 15 Dec 2025 | 1 articles | Viewed by 2468 | Submission Open
Keywords: machine learning; artificial intelligence; computational neuroscience; deep learning; neuroimaging; brain– computer interfaces; neural signal processing; cognitive modeling; neurodegenerative diseases; explainable AI
(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
Perinatal Psychiatry: Mental Health During Pregnancy and the Postpartum
edited by Saulo Gantes Tractenberg, and Tagma Marina Schneider Donelli
submission deadline 15 Dec 2025 | 1 articles | Viewed by 941 | Submission Open
Keywords: perinatal; postpartum; mental health; pregnancy; postpartum depression; postpartum psychosis; psychiatric disorders; puerperal disorders; infant; perinatal care
(This special issue belongs to the Section Neuropsychiatry)
Advanced Optical Neuroimaging and Neurotransmitter Analysis in Cortical Circuits and Sensory Processing
edited by
submission deadline 15 Dec 2025 | Viewed by 129 | Submission Open
Keywords: Optical neuroimaging; Neurotransmitter dynamics; Cortical circuits; Sensory processing; Fiber Photometry; Two-Photon microscopy; Neuromodulation; Neurological disorders; Neurophysiological diseases
(This special issue belongs to the Section Systems Neuroscience)
The Microbiome in Neurological Disorders
edited by
submission deadline 20 Dec 2025 | Viewed by 296 | Submission Open
Keywords: microbiome; brain– microbiome axis; brain– gut axis; neurological disorders; neurodegenerative; neurodevelopmental; neuroinflammatory; human microbiome
Anti-Aggregation Therapies Targeting Amyloid-Beta, Tau and Alpha-Synuclein and Other Proteins Associated with Neurodegenerative Disorders
edited by
submission deadline 20 Dec 2025 | Viewed by 147 | Submission Open
Keywords: amyloid-beta (Aβ ) aggregation; Tau aggregation; alpha-synuclein (α -Syn) aggregation; TAR DNA-binding protein 43 (TDP-43) aggregation; superoxide dismutase (SOD1) aggregation; Huntingtin (HTT) aggregation; prion protein (PrPᶜ); protein aggregation; anti-protein aggregating agents; proteinopathies; neurodegeneration
(This special issue belongs to the Section Neurodegenerative Diseases)
Falls: Developing, Understanding, and Communicating Effective Interventions
edited by and
submission deadline 20 Dec 2025 | Viewed by 123 | Submission Open
Keywords: gait; posture; fall prevention; balance disorders; rehabilitation; assistive technology; neurological disorders; wearable devices; intervention strategies; clinical practice; intervention communication
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Primary Progressive Aphasia: What Happens to Speech and Language? What Can We Do to Help?
edited by , Anna P. Volkmer, Jason D. Warren and
submission deadline 21 Dec 2025 | 3 articles | Viewed by 1800 | Submission Open
Keywords: primary progressive aphasia; language; brain; communication; cognition
(This special issue belongs to the Section Neurolinguistics)
Advances in Speech and Language Research for Cognitive Well-Being in Aging
edited by , Lilian Cristine Hubner and Erica Dos Santos Rodrigues
submission deadline 21 Dec 2025 | 1 articles | Viewed by 900 | Submission Open
Keywords: communication skills; language abilities; speech; cognitive function; neurodegenerative diseases; neuromodulation
(This special issue belongs to the Section Neurolinguistics)
Artificial Intelligence in Neurological Disorders submission deadline 24 Dec 2025 | Viewed by 475 | Submission Open
Keywords: artificial intelligence; neurological disorders; machine learning; deep learning; neuroimaging; Alzheimer’ s disease; Parkinson’ s disease; predictive analytics; personalized medicine; ethical AI
(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
Risk Factors for Tinnitus and Tinnitus-Related Disease
edited by and Alberto Eibenstein
submission deadline 25 Dec 2025 | 1 articles | Viewed by 2062 | Submission Open
Keywords: tinnitus; anxiety; depression; stress; migraine; hearing loss; insomnia; biomarkers; noise; ototoxicity
(This special issue belongs to the Section Sensory and Motor Neuroscience)
Brain Stimulation for Psychiatric Disorders: Emerging Evidence and New Perspectives—2nd Edition submission deadline 30 Dec 2025 | 8 articles | Viewed by 18370 | Submission Open
Keywords: repetitive transcranial magnetic stimulation (rTMS) and Theta burst stimulation (TBS); transcranial electrical stimulation (tES) (transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); transcranial random noise stimulation (tRNS)); magnetic seizure therapy (MST); depression; bipolar disorder; and other mood disorders; schizophrenia and psychosis; obsessive– compulsive disorder and anxiety disorders; substance use disorders; neurodevelopmental disorders (ADHD; autism); neuroimaging; neurophysiology; cognition
(This special issue belongs to the Section Neuropsychiatry)
Cellular and Molecular Mechanisms Regulating Neuronal Function, Homeostasis, and Disease submission deadline 31 Dec 2025 | 4 articles | Viewed by 5460 | Submission Open
Keywords: molecular mechanisms; cellular mechanisms; neuronal function; neuronal homeostasis; neuronal health; neuronal development; neuronal metabolism; neuron– glia interactions; synaptic plasticity; biomarkers of early diagnosis; neurodegeneration; brain diseases
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
At the Frontiers of Neurorehabilitation: 3rd Edition
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 5136 | Submission Open
Keywords: CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; optimization of clinical care; motor learning; cognitive reinforcement; motivational issues; relevant outcome measures; innovative approaches; rehabilitation devices; neuro-prosthetics; brain– computer interfaces; clinical trials for validation; regulatory issues; activities of daily living (ADLs) autonomy; quality of life; neurodevelopmental disorder
(This special issue belongs to the Section Neurorehabilitation)
Neural Mechanisms Underlying Sensorimotor Learning and Plasticity: Novel Advances and Future Perspectives
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5132 | Submission Open
Keywords: sensorimotor learning; brain plasticity; cognitive neuroscience; neurophysiology; non-invasive brain stimulation; EEG; neuromodulation; motor system; visual system; somatosensory system
(This special issue belongs to the Section Systems Neuroscience)
The Future of Human–Machine Collaboration: AI in Neural Rehabilitation and Assistive Technologies
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2143 | Submission Open
Keywords: artificial intelligence; neural rehabilitation; brain– computer interface; neuroprosthetics; machine learning; rehabilitation robotics; neuroengineering; assistive technology; wearable devices; neurosignal processing
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI submission deadline 31 Dec 2025 | 2 articles | Viewed by 1823 | Submission Open
Keywords: lifespan speech and language disorders; lifespan communication disorders; special learning disabilities; lifespan voice and swallowing disorders; assessment; intervention; innovations; neuromodulation; artificial intelligence
(This special issue belongs to the Section Neurolinguistics)
Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders
edited by and Ana Lucia De Paul
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1354 | Submission Open
Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Advances in Psychopharmacology in Neurodevelopmental Disorders (NDDs)
edited by Shoumitro Deb
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1202 | Submission Open
Keywords: neurodevelopmental disorders; psychopharmacology; research; recent advances; mental health medicine
(This special issue belongs to the Section Neuropharmacology and Neuropathology)
Substance Abuse in the Psychiatric Population submission deadline 31 Dec 2025 | 1 articles | Viewed by 1055 | Submission Open
Keywords: substance abuse disorder; genetics (expression; SNPs); epigenetics; schizophrenia; forensic psychiatry; depression; bipolar disorder; translational research; personality disorders; imaging (PET; SPECT; MRI); general psychiatry
(This special issue belongs to the Section Neuropsychiatry)
Lifestyle and Risk Factors for Multiple Sclerosis submission deadline 31 Dec 2025 | 1 articles | Viewed by 834 | Submission Open
Keywords: multiple sclerosis; lifestyle; risk factors; nutrition; pollution; sleep quality; progression
(This special issue belongs to the Section Neurodegenerative Diseases)
Neuroscience of Learning, Mental Health, and Cultural Adaptation: Cognitive, Pedagogical, and Psychological Perspectives submission deadline 31 Dec 2025 | Viewed by 338 | Submission Open
Keywords: cognitive neuroscience; mental health and learning; cultural adaptation; educational neuroscience; neuropsychology of learning; pedagogical interventions; emotional resilience in education; multicultural and inclusive education; neural mechanisms of learning; cross-cultural pedagogy
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Quantifying Motor Neurone Disease: Advances and Challenges in Developing Biomarkers, Predictive Models and Outcome Measures
edited by Roisin McMackin and
submission deadline 31 Dec 2025 | Viewed by 233 | Submission Open
Keywords: amyotrophic lateral sclerosis; primary lateral sclerosis; progressive muscular atrophy; biomarkers (cognition; neurophysiology; biofluid markers; neuroimaging); modelling; therapeutic development; early detection and diagnosis; precision medicine
(This special issue belongs to the Section Sensory and Motor Neuroscience)
New Advances in Functional Neurosurgery—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 230 | Submission Open
Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Applications of Cognitive Behavioral Therapy in Mental Disorders
edited by Maria Rita Sergi
submission deadline 31 Dec 2025 | Viewed by 139 | Submission Open
Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions
Advanced Neuromodulation Therapies for Chronic Pain and Psychiatric Disorders
edited by and Marina de Goes Salvetti
submission deadline 31 Dec 2025 | Viewed by 119 | Submission Open
Keywords: repetitive transcranial magnetic stimulation (rTMS); theta burst stimulation (TBS); chronic pain; treatment-resistant depression; neuromodulation; tDCS; tACS; non-invasive brain stimulation; neuroplasticity; functional connectivity; major depressive disorder and generalized anxiety disorder
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Multiple Sclerosis Across the Age Spectrum—Beyond Inflammation
edited by
submission deadline 1 Jan 2026 | Viewed by 104 | Submission Open
Keywords: multiple sclerosis; neurodegeneration; disability; cognition; functional outcomes; rehabilitation; pediatric-onset; late onset; ageing
Neural Mechanisms Underlying Social Cognition and Emotional Processing
edited by
submission deadline 10 Jan 2026 | 1 articles | Viewed by 350 | Submission Open
Keywords: social cognition; emotional processing; social neuroscience; developmental neuroscience
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Deep Research into Stroke
edited by
submission deadline 15 Jan 2026 | 2 articles | Viewed by 3041 | Submission Open
Keywords: stroke; rehabilitation; neuromodulation; physical therapy; robotics; artificial intelligence; neuroimaging; deep learning; machine learning; exercise
(This special issue belongs to the Section Neurorehabilitation)
Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease
edited by Yuta Katsumi, and Bradford C. Dickerson
submission deadline 15 Jan 2026 | 2 articles | Viewed by 1666 | Submission Open
Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Beyond Boundaries: Current Advances in Developmental Learning Disorders
edited by Daniela Traficante and
submission deadline 15 Jan 2026 | 1 articles | Viewed by 568 | Submission Open
Keywords: developmental learning disorders; transdiagnostic approach; comorbidity; domain-general components
(This special issue belongs to the Section Neuropsychology)
Non-Invasive Neurotechnologies for Cognitive Augmentation submission deadline 15 Jan 2026 | Viewed by 130 | Submission Open
Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology
(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)
Inflammation and Central Nervous System
edited by
submission deadline 15 Jan 2026 | Viewed by 105 | Submission Open
Keywords: inflammation; inflammasome; brain injury; neurodegeneration; aging; cognition; brain senescence
(This special issue belongs to the Section Systems Neuroscience)
Anxiety, Depression and Stress
edited by
submission deadline 18 Jan 2026 | 4 articles | Viewed by 3309 | Submission Open
Keywords: anxiety; depression; stress; NMDA modulators; brain stimulation; anti-inflammatory agents; psychosocial interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Perception Across Disciplines: Exploring the Intersections of Cognitive, Social, Affective and Neural Dimensions
edited by
submission deadline 18 Jan 2026 | 1 articles | Viewed by 1251 | Submission Open
Keywords: sensory processing; cognitive systems; perception-action binding; multimodal processing; neural foundations; socio-affective systems; computational models; interdisciplinary research
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition
edited by
submission deadline 20 Jan 2026 | 4 articles | Viewed by 9641 | Submission Open
Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Brain Boosting: Recent Advances in Neurostimulation on Cognitive Functions and Behavioral Performance
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 2192 | Submission Open
Keywords: TMS; cognitive functions; behavioral interventions; brain plasticity; addictions; hypnosis; neurostimulation
(This special issue belongs to the Section Behavioral Neuroscience)
Translational EEG Biomarkers in Animal Models: Bridging Pre-Clinical Findings to Human Neuroscience
edited by and Cestmir Vejmola
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1631 | Submission Open
Keywords: EEG; ECoG; biomarker; animal model; pre-clinical
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Advances in the Treatment of Depression, Anxiety, and Other Psychiatric Disorders
edited by Danielle S. Cha
submission deadline 20 Jan 2026 | Viewed by 346 | Submission Open
Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease
(This special issue belongs to the Section Neuropsychiatry)
Neuropathic Pain: Pathophysiology, Diagnosis and Treatment
edited by Marcos Brioschi and
submission deadline 20 Jan 2026 | Viewed by 94 | Submission Open
Keywords: neuropathic pain; pathophysiology; diagnosis; neuroimaging; thermography; artificial intelligence; treatment; rehabilitation; translational research; neuromodulation
(This special issue belongs to the Section Sensory and Motor Neuroscience)
The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System
edited by
submission deadline 23 Jan 2026 | 2 articles | Viewed by 6271 | Submission Open
Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Emerging Trends in Youth Mental Health
edited by
submission deadline 23 Jan 2026 | 1 articles | Viewed by 839 | Submission Open
Keywords: mental health; adolescent mental health; young adult; stress; psychological; social media; climate change; identity development; digital health; school health services
(This special issue belongs to the Section Neuropsychology)
Assessment and Rehabilitation of Cognitive Function in Neurological Disorders
edited by Gilles Naeije
submission deadline 25 Jan 2026 | 1 articles | Viewed by 955 | Submission Open
Keywords: post-stroke cognitive impairment; diaschisis; cerebellum; cortico-cerebellar connectivity; neuromodulation; transcranial cerebellar stimulation; cognitive rehabilitation; functional connectivity
(This special issue belongs to the Section Neurorehabilitation)
Advances in Neurofeedback Research
edited by
submission deadline 25 Jan 2026 | 1 articles | Viewed by 895 | Submission Open
Keywords: neurofeedback; brain– computer interface; neurophenomenology; EEG; rt-fMRI; fNIRS-neurofeedback
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
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