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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Translating Gut–Brain Crosstalk into Novel Neurological Treatments

edited by

Diego Iacono

submission deadline 15 Jul 2026 | Viewed by 236 | Submission Open

Keywords: gut– brain axis; central nervous system; enteric nervous system; anatomy; microbiota; GI-to-brain signals; brain-to-GI signals; neuroinflammation

(This special issue belongs to the Section Systems Neuroscience)

At the Frontiers of Neurorehabilitation: 3rd Edition

edited by

Manuel Gaviria

submission deadline 17 Jul 2026 | 8 articles | Viewed by 12767 | Submission Open

Keywords: CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; optimization of clinical care; motor learning; cognitive reinforcement; motivational issues; relevant outcome measures; innovative approaches; rehabilitation devices; neuro-prosthetics; brain– computer interfaces; clinical trials for validation; regulatory issues; activities of daily living (ADLs) autonomy; quality of life; neurodevelopmental disorder

(This special issue belongs to the Section Neurorehabilitation)

Advances in Emotion Processing and Cognitive Neuropsychology

edited by

Pasquale La Malva

submission deadline 20 Jul 2026 | 9 articles | Viewed by 19422 | Submission Open

Keywords: emotion processing; cognitive neuropsychology; affective neuroscience; emotion regulation; executive functions; neuroimaging (fMRI; EEG); non-invasive brain stimulation (TMS; tDCS); psychophysiological measures; age-related differences; translational research

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Cerebrospinal Fluid Dynamics in Brain Health and Disease

edited by

Renan B. Domingues

submission deadline 20 Jul 2026 | Viewed by 235 | Submission Open

Keywords: cerebrospinal fluid; glymphatic system; intracranial pressure; idiopathic intracranial hypertension; normal pressure hydrocephalus; neuroinflammation; neuroinfection; neurodegeneration; biomarkers; brain clearance

(This special issue belongs to the Section Systems Neuroscience)

The Impact of Social Media on Human Behavior and Mental Health

edited by

Ebenezer Larnyo

and Henry Asante Antwi

submission deadline 23 Jul 2026 | Viewed by 793 | Submission Open

Keywords: social media; mental health; human behavior; psychological well-being; digital addiction; cognitive impairment; online communities; public health; health behavior change; algorithmic bias

(This special issue belongs to the Section Neuropsychology)

Chronic Non-Infectious Diseases with a High Impact on the Central Nervous System

edited by

Grazyna Lietzau

submission deadline 24 Jul 2026 | 6 articles | Viewed by 25770 | Submission Open

Keywords: mental disorders; metabolic diseases; migraine; movement disorders; multiple sclerosis; neurodegenerative diseases; stroke

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advancements in Diagnosis and Treatment of Stroke and Cerebral Aneurysms: A Call for Innovative Research Submissions

edited by

Sherief Ghozy

, Ram Kadirvel and Ajay Malhotra

submission deadline 24 Jul 2026 | 9 articles | Viewed by 19088 | Submission Open

Keywords: stroke; cerebral aneurysms; minimally invasive surgical; imaging; neurovascular

(This special issue belongs to the Section Neurorehabilitation)

Chemotherapy-Associated Brain Damage—Translational Insights from Pre-Clinical and Clinical Research

edited by

Nikola Stojanović

submission deadline 25 Jul 2026 | Viewed by 301 | Submission Open

Keywords: chemotherapeutics; brain damage; brain fog; translation studies; preventing brain damage

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Advances in Theory and Applications in Geriatric Musculoskeletal and Neurological Therapy

edited by Anna Christakou

submission deadline 25 Jul 2026 | Viewed by 255 | Submission Open

Keywords: myopathy; dementia; geriatric medicine; geriatric physiotherapy; osteoporosis; falls; arthritis; muscle weakness; shoulder dysfunction; rehabilitation

(This special issue belongs to the Section Systems Neuroscience)

Artificial Intelligence in Neurological Disorders

edited by

Rahul Kashyap

and

Pallavi Dinesh Shirsat

submission deadline 30 Jul 2026 | 3 articles | Viewed by 3556 | Submission Open

Keywords: artificial intelligence; neurological disorders; machine learning; deep learning; neuroimaging; Alzheimer’ s disease; Parkinson’ s disease; predictive analytics; personalized medicine; ethical AI

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Interlimb Transfer of Sensorimotor Learning

edited by

Jinsung Wang

and

Yuming Lei

submission deadline 30 Jul 2026 | 1 articles | Viewed by 993 | Submission Open

Keywords: inter-limb transfer; inter-manual transfer; cross-education; sensorimotor learning; motor adaptation; skill acquisition; motor control; neuroplasticity

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Decoding Motor Control: Multimodal Approaches to Cortical Plasticity and Learning

edited by

Gonzalo Marquez

and

David Colomer-Poveda

submission deadline 30 Jul 2026 | Viewed by 248 | Submission Open

Keywords: motor control; cortical plasticity; motor learning; multimodal approaches; neurorehabilitation; brain– machine interfaces; computational neuroscience; neuroimaging; electrophysiology; biomechanics

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Applications of Neuroimaging in Healthy Aging and Neurodegenerative Diseases

edited by Samaneh Nemati

submission deadline 30 Jul 2026 | Viewed by 183 | Submission Open

Keywords: neuroimaging; healthy aging; neurodegenerative disorders; cognitive aging; multimodal imaging; network neuroscience; functional connectivity; structural connectivity; machine learning; biomarkers

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI

edited by

Dionysios Tafiadis

, Nafsika Ziavra,

Angelos Papadopoulos

and

Konstantinos Drosos

submission deadline 31 Jul 2026 | 6 articles | Viewed by 8917 | Submission Open

Keywords: lifespan speech and language disorders; lifespan communication disorders; special learning disabilities; lifespan voice and swallowing disorders; assessment; intervention; innovations; neuromodulation; artificial intelligence

(This special issue belongs to the Section Neurolinguistics)

Diagnosis and Treatment of Post-Stroke and Progressive Aphasias

edited by Sigfus Kristinsson and Sladjana Lukic

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3853 | Submission Open

Keywords: post-stroke aphasia; primary progressive aphasia; lesion– symptom mapping; neuroimaging; speech and language treatment; neural markers

(This special issue belongs to the Section Neurolinguistics)

Biobehavioral Neuroscience and Pain Medicine: Assessment and Management of Pain

edited by

Raúl Ferrer-Peña

and

Francisco Gurdiel-Álvarez

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2076 | Submission Open

Keywords: biobehavioral neuroscience; chronic pain; pain modulation; emotion and motor control; brain plasticity; pain assessment; neurobehavioral markers; central sensitization; behavioral interventions; translational pain research

(This special issue belongs to the Section Behavioral Neuroscience)

Electrophysiological Approaches to Cognitive Neuroscience

edited by

Andrés Antonio González Garrido

and

Steven Woltering

submission deadline 31 Jul 2026 | 1 articles | Viewed by 965 | Submission Open

Keywords: electroencephalography (EEG); cognition; neurocognitive processes; brain dynamics; cognitive neuroscience; event-related potentials (ERP); functional connectivity; neural oscillations; multimodal neuroimaging; clinical EEG

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Deep Brain Stimulation (DBS)—Current Status and Future Directions

edited by Yousef Salimpour

submission deadline 31 Jul 2026 | 1 articles | Viewed by 906 | Submission Open

Keywords: deep brain stimulation; neuromodulation; adaptive closed-loop systems; directional leads; neural biomarkers artificial intelligence; personalization treatment; biocompatible materials

(This special issue belongs to the Section Neurodegenerative Diseases)

From Neural Mechanisms to Plasticity-Driven Therapies: A Focus on Auditory Processing

edited by Giulia Cartocci,

Bianca Maria Serena Inguscio

Dario Rossi

and Saviana Antonella Barbati

submission deadline 31 Jul 2026 | 1 articles | Viewed by 881 | Submission Open

Keywords: neuroplasticity; sensory deprivation; hearing loss; cochlear implants; hearing aids; sensory disorders

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Substance Use and Addiction: From Molecular Mechanisms to Treatment

edited by

Davide Arillotta

Giuseppe Floresta

and

Fabrizio Schifano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 546 | Submission Open

Keywords: substance use disorders; addiction; reward; neuroplasticity; craving; precision medicine; translational neuroscience; co-occurring substance use and mental disorders

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Applications of Cognitive Behavioral Therapy in Mental Disorders

edited by Maria Rita Sergi

submission deadline 31 Jul 2026 | Viewed by 380 | Submission Open

Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions

Human-Centered Robotics Applications in Rehabilitation of Individuals with Neurological Conditions

edited by Giovanni Morone

submission deadline 31 Jul 2026 | Viewed by 332 | Submission Open

Keywords: robotics; neurological disabilities; stroke; gait; rehabilitation

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Basic Mechanisms of Speech Production, Speech Perception and Perception-Production Link

edited by Yi Xu and

Anqi Xu

submission deadline 31 Jul 2026 | Viewed by 322 | Submission Open

Keywords: speech production; speech perception; production-perception link; articulatory dynamics; sensorimotor learning; speech acquisition; vocal learning; perceptual learning; computational modelling; modelling simulation

(This special issue belongs to the Section Neurolinguistics)

The Intersection of Mind and Muscle: Motor Control and Psychology

edited by

Wanxiang Yao

and Guang Yue

submission deadline 31 Jul 2026 | Viewed by 284 | Submission Open

Keywords: motor control; motor learning cognition; neurophysiology; psychophysiology; neuroimaging; mind– body interaction

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Targeted Therapy of Glioma: Current Developments in Targeted Drug Delivery Systems

edited by Łukasz Uram

submission deadline 31 Jul 2026 | Viewed by 247 | Submission Open

Keywords: glioblastoma multiforme therapy; targeted glioma therapy; in vivo and in vitro studies; blood– brain barrier crossing; repurposing drugs; nanoparticles as targeting factors

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovative Research on the Health, Physiological and Neuroscientific Consequences of Mental Health Conditions

edited by

Jeffrey L. Kibler

submission deadline 31 Jul 2026 | Viewed by 218 | Submission Open

Keywords: health risks; psychophysiological; neuroscience; mental health

(This special issue belongs to the Section Neuropsychology)

Chronic Pain: Symptoms, Causes, Real World Evidence, and Diagnosis

edited by Guy Hans

submission deadline 1 Aug 2026 | 1 articles | Viewed by 1166 | Submission Open

Keywords: neuropathic pain; visceral pain; nociplastic pain; pharmacology of pain; invasive pain therapies; multidisciplinary approach; real-world evidence; pre-emptive analgesia; diagnostic evaluation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neuroimaging Biomarkers for the Diagnosis of Mental Disorders

edited by

Fabrício Pereira

submission deadline 10 Aug 2026 | Viewed by 482 | Submission Open

Keywords: neuroimaging biomarkers; multimodality imaging; precision psychiatry; translational neuropsychiatric research; neuroimaging-informed phenotype; personalized mental health; computer-aided diagnosis; artificial intelligence in psychiatry; imaging-based prognosis

(This special issue belongs to the Section Neuropsychiatry)

Neuroimmunology: Past, Present, and Promise

edited by

Maria Elsa Gambuzza

submission deadline 10 Aug 2026 | Viewed by 224 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative disorders; multiple sclerosis; neurological disorders; neuropsychiatric disorders; peripheral nervous system; neuro-oncological conditions

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Aug 2026 | 5 articles | Viewed by 6334 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Non-Invasive Neurotechnologies for Cognitive Augmentation

edited by

Caterina Cinel

Davide Valeriani

and

Saugat Bhattacharyya

submission deadline 15 Aug 2026 | 2 articles | Viewed by 2144 | Submission Open

Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Advances in Parkinson’s Disease

edited by

Osmar Pinto Neto

submission deadline 15 Aug 2026 | Viewed by 307 | Submission Open

Keywords: Parkinson’ s disease; neurodegeneration; motor control; digital biomarkers; sensorimotor integration; neuromuscular physiology; machine learning and signal analysis; early diagnosis; neuromodulation; translational neuroscience

(This special issue belongs to the Section Neurodegenerative Diseases)

Bridging Neurodegeneration and Neuroinflammation: Novel Therapeutic Approaches

edited by

Maheedhar Kodali

submission deadline 15 Aug 2026 | Viewed by 288 | Submission Open

Keywords: neurodegeneration; neuroinflammation; transcriptomic alterations; extracellular vesicles; mTOR signaling; autophagy and mitophagy; synaptogenesis brain repair preclinical models; therapeutic interventions

(This special issue belongs to the Section Neurodegenerative Diseases)

Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia

edited by Chiara Baglioni and Debora Meneo

submission deadline 20 Aug 2026 | 3 articles | Viewed by 6864 | Submission Open

Keywords: sleep health; insomnia; emotional processes; pre-sleep behaviours; cognitive processes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Writing on the Brain: Current Trends, Challenges and Future Venues

edited by Roberto Limongi

submission deadline 20 Aug 2026 | Viewed by 409 | Submission Open

Keywords: writing and the brain; writing to learn; epistemic writing; expressive writing; memory and writing

(This special issue belongs to the Section Neurolinguistics)

Neurosurgery: Minimally Invasive Surgery in Brain and Spine—2nd Edition

edited by Christopher Ahuja

submission deadline 20 Aug 2026 | Viewed by 322 | Submission Open

Keywords: minimally invasive surgery; neurosurgery; brain; spine

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Defining Emotion: A Collection of Current Models

edited by

Peter Walla

submission deadline 21 Aug 2026 | 8 articles | Viewed by 29280 | Submission Open

Keywords: emotion; affect; affection; affective processing of feelings; mood; cognitive processing

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroeducation: Bridging Cognitive Science and Classroom Practice

edited by Yuvaraj Rajamanickam

submission deadline 25 Aug 2026 | 3 articles | Viewed by 11785 | Submission Open

Keywords: education; neuroscience; learning and memory; neurodevelopmental disorders; emotions; cognitive skills; neuroplasticity; EEG; neuroimaging; school; classroom; educational interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroprotection for Neurodegenerative Diseases: Current Status and Future Perspectives

edited by

Adriano Martimbianco de Assis

submission deadline 25 Aug 2026 | Viewed by 361 | Submission Open

Keywords: neuroprotection; neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis (ALS); biomarkers; neuroinflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neurodegenerative Diseases)

Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders

edited by

Alexandra Susana Latini

and Ana Lucia De Paul

submission deadline 28 Aug 2026 | 4 articles | Viewed by 5360 | Submission Open

Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovations in Skull Base Surgery

edited by

Fumihiro Matano

submission deadline 29 Aug 2026 | 1 articles | Viewed by 1818 | Submission Open

Keywords: microsurgery; endoscopic skull base surgery; exoscopic surgery; minimally invasive neurosurgery; skull base and cerebrovascular surgery; intracranial aneurysm; moyamoya disease; RNF213

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Predictive Processing in Brain and Behavior

edited by Mario Trevino

submission deadline 30 Aug 2026 | 2 articles | Viewed by 2118 | Submission Open

Keywords: predictive processing; sensorimotor integration; visuomotor coordination; prediction error; adaptive behavior; anticipatory gaze; motor learning; neural dynamics

(This special issue belongs to the Section Behavioral Neuroscience)

Exploring Human Emotion: From Brain to Behavior Across Disciplines

edited by

Simona Massimino

and

Carmelo M. Vicario

submission deadline 30 Aug 2026 | Viewed by 308 | Submission Open

Keywords: emotion; perception; cognition; neural process

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Outcome Measures in Rehabilitation

edited by

Antonio Nardone

and

Irene Aprile

submission deadline 31 Aug 2026 | 8 articles | Viewed by 9551 | Submission Open

Keywords: outcome measures; qualitative measures; quantitative measures; neurologic rehabilitation; musculoskeletal rehabilitation; cardiopulmonary rehabilitation; robotic rehabilitation; movement analysis; gait analysis

(This special issue belongs to the Section Neurorehabilitation)

Recent Advances in Hearing Impairment: 2nd Edition

edited by

Agnieszka Szczepek

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3181 | Submission Open

Keywords: hearing loss; ototoxicity; autoimmune disease; cochlear synaptopathy; hair cell loss; spiral ganglion damage; translational research; audiology; animal models; biomarkers for hearing loss

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances and Perspectives in Stereotactic Neurosurgery and Radiosurgery

edited by

Michele Longhi

and Antonio Nicolato

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1992 | Submission Open

Keywords: gamma knife; radiosurgery; focused ultrasound; stereotactic neurosurgery; DBS

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

New Advances in Functional Neurosurgery—2nd Edition

edited by

Nicola Montano

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1887 | Submission Open

Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Cognitive Impairment Associated with Psychiatric Disorders

edited by Rune Raudeberg and Eivind Haga Ronold

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1451 | Submission Open

Keywords: cognitive impairment; therapeutic interventions; mental disorders; substance use disorders; neuroimaging; biomarkers; epigenetics

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Memory and Cognition in Bi/Multilingual Minds: Mechanisms, Models, and Developmental Pathways

edited by

Meesha Warmington

and

Diana R. Pereira

submission deadline 31 Aug 2026 | Viewed by 453 | Submission Open

Keywords: bilingualism; multilingualism; memory and cognition; language control; working memory; episodic memory; cross-linguistic transfer; executive function; neurocognitive mechanisms; computational modeling

(This special issue belongs to the Section Neurolinguistics)

Modulation of the Tumor Microenvironment for the Treatment of Brain Tumors

edited by

Lam C. Fred

and Cecile Maire

submission deadline 31 Aug 2026 | 1 articles | Viewed by 428 | Submission Open

Keywords: tumor microenvironment; immuno-oncology; primary brain tumors; metastatic brain tumors; neuro-oncology

(This special issue belongs to the Section Neuro-oncology)

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