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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis and Treatment of Post-Stroke and Progressive Aphasias

edited by Sigfus Kristinsson and Sladjana Lukic

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3950 | Submission Open

Keywords: post-stroke aphasia; primary progressive aphasia; lesion– symptom mapping; neuroimaging; speech and language treatment; neural markers

(This special issue belongs to the Section Neurolinguistics)

Biobehavioral Neuroscience and Pain Medicine: Assessment and Management of Pain

edited by

Raúl Ferrer-Peña

and

Francisco Gurdiel-Álvarez

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2245 | Submission Open

Keywords: biobehavioral neuroscience; chronic pain; pain modulation; emotion and motor control; brain plasticity; pain assessment; neurobehavioral markers; central sensitization; behavioral interventions; translational pain research

(This special issue belongs to the Section Behavioral Neuroscience)

Electrophysiological Approaches to Cognitive Neuroscience

edited by

Andrés Antonio González Garrido

and

Steven Woltering

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1257 | Submission Open

Keywords: electroencephalography (EEG); cognition; neurocognitive processes; brain dynamics; cognitive neuroscience; event-related potentials (ERP); functional connectivity; neural oscillations; multimodal neuroimaging; clinical EEG

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Deep Brain Stimulation (DBS)—Current Status and Future Directions

edited by Yousef Salimpour

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1007 | Submission Open

Keywords: deep brain stimulation; neuromodulation; adaptive closed-loop systems; directional leads; neural biomarkers artificial intelligence; personalization treatment; biocompatible materials

(This special issue belongs to the Section Neurodegenerative Diseases)

From Neural Mechanisms to Plasticity-Driven Therapies: A Focus on Auditory Processing

edited by Giulia Cartocci,

Bianca Maria Serena Inguscio

Dario Rossi

and Saviana Antonella Barbati

submission deadline 31 Jul 2026 | 1 articles | Viewed by 936 | Submission Open

Keywords: neuroplasticity; sensory deprivation; hearing loss; cochlear implants; hearing aids; sensory disorders

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Substance Use and Addiction: From Molecular Mechanisms to Treatment

edited by

Davide Arillotta

Giuseppe Floresta

and

Fabrizio Schifano

submission deadline 31 Jul 2026 | 1 articles | Viewed by 628 | Submission Open

Keywords: substance use disorders; addiction; reward; neuroplasticity; craving; precision medicine; translational neuroscience; co-occurring substance use and mental disorders

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Applications of Cognitive Behavioral Therapy in Mental Disorders

edited by Maria Rita Sergi

submission deadline 31 Jul 2026 | Viewed by 393 | Submission Open

Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions

Human-Centered Robotics Applications in Rehabilitation of Individuals with Neurological Conditions

edited by Giovanni Morone

submission deadline 31 Jul 2026 | Viewed by 342 | Submission Open

Keywords: robotics; neurological disabilities; stroke; gait; rehabilitation

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Basic Mechanisms of Speech Production, Speech Perception and Perception-Production Link

edited by Yi Xu and

Anqi Xu

submission deadline 31 Jul 2026 | Viewed by 340 | Submission Open

Keywords: speech production; speech perception; production-perception link; articulatory dynamics; sensorimotor learning; speech acquisition; vocal learning; perceptual learning; computational modelling; modelling simulation

(This special issue belongs to the Section Neurolinguistics)

The Intersection of Mind and Muscle: Motor Control and Psychology

edited by

Wanxiang Yao

and Guang Yue

submission deadline 31 Jul 2026 | Viewed by 299 | Submission Open

Keywords: motor control; motor learning cognition; neurophysiology; psychophysiology; neuroimaging; mind– body interaction

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Targeted Therapy of Glioma: Current Developments in Targeted Drug Delivery Systems

edited by Łukasz Uram

submission deadline 31 Jul 2026 | Viewed by 253 | Submission Open

Keywords: glioblastoma multiforme therapy; targeted glioma therapy; in vivo and in vitro studies; blood– brain barrier crossing; repurposing drugs; nanoparticles as targeting factors

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovative Research on the Health, Physiological and Neuroscientific Consequences of Mental Health Conditions

edited by

Jeffrey L. Kibler

submission deadline 31 Jul 2026 | Viewed by 228 | Submission Open

Keywords: health risks; psychophysiological; neuroscience; mental health

(This special issue belongs to the Section Neuropsychology)

Chronic Pain: Symptoms, Causes, Real World Evidence, and Diagnosis

edited by Guy Hans

submission deadline 1 Aug 2026 | 1 articles | Viewed by 1200 | Submission Open

Keywords: neuropathic pain; visceral pain; nociplastic pain; pharmacology of pain; invasive pain therapies; multidisciplinary approach; real-world evidence; pre-emptive analgesia; diagnostic evaluation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neuroimaging Biomarkers for the Diagnosis of Mental Disorders

edited by

Fabrício Pereira

submission deadline 10 Aug 2026 | Viewed by 508 | Submission Open

Keywords: neuroimaging biomarkers; multimodality imaging; precision psychiatry; translational neuropsychiatric research; neuroimaging-informed phenotype; personalized mental health; computer-aided diagnosis; artificial intelligence in psychiatry; imaging-based prognosis

(This special issue belongs to the Section Neuropsychiatry)

Neuroimmunology: Past, Present, and Promise

edited by

Maria Elsa Gambuzza

submission deadline 10 Aug 2026 | Viewed by 240 | Submission Open

Keywords: neuroimmunology; neuroinflammation; neurodegenerative disorders; multiple sclerosis; neurological disorders; neuropsychiatric disorders; peripheral nervous system; neuro-oncological conditions

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Aug 2026 | 5 articles | Viewed by 6533 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Non-Invasive Neurotechnologies for Cognitive Augmentation

edited by

Caterina Cinel

Davide Valeriani

and

Saugat Bhattacharyya

submission deadline 15 Aug 2026 | 2 articles | Viewed by 2256 | Submission Open

Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Advances in Parkinson’s Disease

edited by

Osmar Pinto Neto

submission deadline 15 Aug 2026 | Viewed by 327 | Submission Open

Keywords: Parkinson’ s disease; neurodegeneration; motor control; digital biomarkers; sensorimotor integration; neuromuscular physiology; machine learning and signal analysis; early diagnosis; neuromodulation; translational neuroscience

(This special issue belongs to the Section Neurodegenerative Diseases)

Bridging Neurodegeneration and Neuroinflammation: Novel Therapeutic Approaches

edited by

Maheedhar Kodali

submission deadline 15 Aug 2026 | Viewed by 304 | Submission Open

Keywords: neurodegeneration; neuroinflammation; transcriptomic alterations; extracellular vesicles; mTOR signaling; autophagy and mitophagy; synaptogenesis brain repair preclinical models; therapeutic interventions

(This special issue belongs to the Section Neurodegenerative Diseases)

Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia

edited by Chiara Baglioni and Debora Meneo

submission deadline 20 Aug 2026 | 3 articles | Viewed by 7174 | Submission Open

Keywords: sleep health; insomnia; emotional processes; pre-sleep behaviours; cognitive processes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neurosurgery: Minimally Invasive Surgery in Brain and Spine—2nd Edition

edited by Christopher Ahuja

submission deadline 20 Aug 2026 | 1 articles | Viewed by 600 | Submission Open

Keywords: minimally invasive surgery; neurosurgery; brain; spine

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Writing on the Brain: Current Trends, Challenges and Future Venues

edited by Roberto Limongi

submission deadline 20 Aug 2026 | Viewed by 425 | Submission Open

Keywords: writing and the brain; writing to learn; epistemic writing; expressive writing; memory and writing

(This special issue belongs to the Section Neurolinguistics)

Defining Emotion: A Collection of Current Models

edited by

Peter Walla

submission deadline 21 Aug 2026 | 9 articles | Viewed by 30402 | Submission Open

Keywords: emotion; affect; affection; affective processing of feelings; mood; cognitive processing

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroeducation: Bridging Cognitive Science and Classroom Practice

edited by Yuvaraj Rajamanickam

submission deadline 25 Aug 2026 | 3 articles | Viewed by 12254 | Submission Open

Keywords: education; neuroscience; learning and memory; neurodevelopmental disorders; emotions; cognitive skills; neuroplasticity; EEG; neuroimaging; school; classroom; educational interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Neuroprotection for Neurodegenerative Diseases: Current Status and Future Perspectives

edited by

Adriano Martimbianco de Assis

submission deadline 25 Aug 2026 | Viewed by 375 | Submission Open

Keywords: neuroprotection; neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis (ALS); biomarkers; neuroinflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neurodegenerative Diseases)

Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders

edited by

Alexandra Susana Latini

and Ana Lucia De Paul

submission deadline 28 Aug 2026 | 4 articles | Viewed by 5843 | Submission Open

Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Innovations in Skull Base Surgery

edited by

Fumihiro Matano

submission deadline 29 Aug 2026 | 1 articles | Viewed by 1905 | Submission Open

Keywords: microsurgery; endoscopic skull base surgery; exoscopic surgery; minimally invasive neurosurgery; skull base and cerebrovascular surgery; intracranial aneurysm; moyamoya disease; RNF213

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Predictive Processing in Brain and Behavior

edited by Mario Trevino

submission deadline 30 Aug 2026 | 2 articles | Viewed by 2255 | Submission Open

Keywords: predictive processing; sensorimotor integration; visuomotor coordination; prediction error; adaptive behavior; anticipatory gaze; motor learning; neural dynamics

(This special issue belongs to the Section Behavioral Neuroscience)

Exploring Human Emotion: From Brain to Behavior Across Disciplines

edited by

Simona Massimino

and

Carmelo M. Vicario

submission deadline 30 Aug 2026 | Viewed by 327 | Submission Open

Keywords: emotion; perception; cognition; neural process

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Outcome Measures in Rehabilitation

edited by

Antonio Nardone

and

Irene Aprile

submission deadline 31 Aug 2026 | 8 articles | Viewed by 10012 | Submission Open

Keywords: outcome measures; qualitative measures; quantitative measures; neurologic rehabilitation; musculoskeletal rehabilitation; cardiopulmonary rehabilitation; robotic rehabilitation; movement analysis; gait analysis

(This special issue belongs to the Section Neurorehabilitation)

Recent Advances in Hearing Impairment: 2nd Edition

edited by

Agnieszka Szczepek

submission deadline 31 Aug 2026 | 3 articles | Viewed by 3255 | Submission Open

Keywords: hearing loss; ototoxicity; autoimmune disease; cochlear synaptopathy; hair cell loss; spiral ganglion damage; translational research; audiology; animal models; biomarkers for hearing loss

(This special issue belongs to the Section Sensory and Motor Neuroscience)

New Advances in Functional Neurosurgery—2nd Edition

edited by

Nicola Montano

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2132 | Submission Open

Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advances and Perspectives in Stereotactic Neurosurgery and Radiosurgery

edited by

Michele Longhi

and Antonio Nicolato

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2026 | Submission Open

Keywords: gamma knife; radiosurgery; focused ultrasound; stereotactic neurosurgery; DBS

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Cognitive Impairment Associated with Psychiatric Disorders

edited by Rune Raudeberg and Eivind Haga Ronold

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1732 | Submission Open

Keywords: cognitive impairment; therapeutic interventions; mental disorders; substance use disorders; neuroimaging; biomarkers; epigenetics

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Modulation of the Tumor Microenvironment for the Treatment of Brain Tumors

edited by

Lam C. Fred

and Cecile Maire

submission deadline 31 Aug 2026 | 1 articles | Viewed by 522 | Submission Open

Keywords: tumor microenvironment; immuno-oncology; primary brain tumors; metastatic brain tumors; neuro-oncology

(This special issue belongs to the Section Neuro-oncology)

Memory and Cognition in Bi/Multilingual Minds: Mechanisms, Models, and Developmental Pathways

edited by

Meesha Warmington

and

Diana R. Pereira

submission deadline 31 Aug 2026 | Viewed by 470 | Submission Open

Keywords: bilingualism; multilingualism; memory and cognition; language control; working memory; episodic memory; cross-linguistic transfer; executive function; neurocognitive mechanisms; computational modeling

(This special issue belongs to the Section Neurolinguistics)

Focus on Mental Health and Mental Illness in Adolescents (2nd Edition)

edited by

Dariusz Krok

submission deadline 31 Aug 2026 | Viewed by 241 | Submission Open

Keywords: mental health; mental illness; adolescents; coping with stress; psychotherapy; medical treatment; well-being

(This special issue belongs to the Section Neuropsychiatry)

Diagnosis, Prediction, and Treatment of Neuropsychological Diseases: Application of EEG-Based Technology

edited by

Agnieszka Wosiak

submission deadline 31 Aug 2026 | Viewed by 225 | Submission Open

Keywords: EEG; neuropsychological diseases; biomarkers; machine learning; deep learning; prediction; neurofeedback; brain– computer interfaces; wearable monitoring

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Neuroempowerment and Neurorehabilitation in Home-Based Training Protocols

edited by

Davide Crivelli

submission deadline 31 Aug 2026 | Viewed by 220 | Submission Open

Keywords: neuroempowerment; neurorehabilitation; digital technologies; home-based training; active role

(This special issue belongs to the Section Neurorehabilitation)

Cutaneous Involvement in Neurological Disorders

edited by

Vincenzo Donadio

submission deadline 31 Aug 2026 | Viewed by 170 | Submission Open

Keywords: neurodegenerative diseases; skin sample; biomarkers; synucleinopathies; Fabry disease

(This special issue belongs to the Section Systems Neuroscience)

Understanding the Role and Functions of the Insula in the Brain

edited by

Boucher Olivier

and

Dang Khoa Nguyen

submission deadline 4 Sep 2026 | 2 articles | Viewed by 8252 | Submission Open

Keywords: insula; neuropsychology; disorder; pathology; cognition; emotion; addiction; neurostimulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Biomarker Development in the Early Identification of Autism Spectrum Disorders

edited by Elissar Andari

submission deadline 5 Sep 2026 | 2 articles | Viewed by 3310 | Submission Open

Keywords: autism deep phenotyping; social and affective neuroscience; biomarkers

(This special issue belongs to the Section Developmental Neuroscience)

Assessment and Rehabilitation of Cognitive Function in Neurological Disorders

edited by Gilles Naeije

submission deadline 10 Sep 2026 | 4 articles | Viewed by 5159 | Submission Open

Keywords: post-stroke cognitive impairment; diaschisis; cerebellum; cortico-cerebellar connectivity; neuromodulation; transcranial cerebellar stimulation; cognitive rehabilitation; functional connectivity

(This special issue belongs to the Section Neurorehabilitation)

Broken Mirrors of the Mind: Illusions, Paradoxes, and the Construction of Consciousness

edited by

Baingio Pinna

and Jurgis Skilters

submission deadline 10 Sep 2026 | 1 articles | Viewed by 1068 | Submission Open

Keywords: perception; illusions; consciousness

(This special issue belongs to the Section Neuropsychology)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 15 Sep 2026 | 2 articles | Viewed by 12744 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Molecular Neurobiology and Behavioral Mechanisms in Psychiatric Disorders

edited by Chanpreet Singh and Jin Xu

submission deadline 15 Sep 2026 | 2 articles | Viewed by 4420 | Submission Open

Keywords: molecular neurobiology; psychiatric disorders; neuromodulation; neural circuits; behavior and cognition; neurochemical signaling; neuroimmune interactions; stress and addiction; translational neuroscience; multi-omics and neuroimaging; biomarkers and therapeutics

(This special issue belongs to the Section Behavioral Neuroscience)

Mental Images and the Brain: From Cognitive Neuropsychology to Functional Neuroimaging

edited by

Anna Maria Berardi

submission deadline 15 Sep 2026 | 2 articles | Viewed by 2794 | Submission Open

Keywords: mental imagery; visual perception; dorsal visual stream; ventral visual stream; object; spatial; brain lesion; functional brain imaging; aphantasia; hyperphantasia

(This special issue belongs to the Section Neuropsychology)

Mindfulness and Emotion Regulation

edited by

Ciro Conversano

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1127 | Submission Open

Keywords: mindfulness; emotion regulation; affective neuroscience; emotional cognition; interoception; contemplative practices; psychophysiology; neural plasticity; stress reactivity; self-regulation

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Next-Generation Tools in Neurosurgery: Robotics, Imaging and Beyond

edited by Salvatore M. Cardali and

Giada Garufi

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1078 | Submission Open

Keywords: neurosurgery; robotics; artificial intelligence; AI; neuronavigation; augmented reality

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Examining Executive Function in Early Childhood: Context, Individual Differences and Interventions

edited by

Lisa Boyce

and Sophia D'Agostino

submission deadline 15 Sep 2026 | Viewed by 491 | Submission Open

Keywords: early childhood; cognitive development; executive function; early intervention; developmental trajectories; neurodevelopment

(This special issue belongs to the Section Behavioral Neuroscience)

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