Cellular and Molecular Mechanisms Regulating Neuronal Function, Homeostasis, and Disease
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 1847
Special Issue Editors
2. UCIBIO—Applied Molecular Biosciences Unit, Translational Toxicology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Gandra, Portugal
Interests: molecular motors; intracellular transport; cell biology; molecular biology; neurodegeneration; drugs of abuse; pharmacology; toxicology; neurotoxicology; forensic sciences
Special Issues, Collections and Topics in MDPI journals
2. UCIBIO-Applied Molecular Biosciences Unit, Toxicologic Pathology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Gandra, Portugal
Interests: cell biology; molecular biology; pharmacology; neurodegeneration; toxicology; genetics; oncobiology; cytoskeleton
Special Issue Information
Dear Colleagues,
Neuronal activity is governed by intricate signaling pathways, ion channel dynamics, and synaptic mechanisms, which together influence processes such as neurotransmission, plasticity, and metabolic regulation. An optimal interplay among distinct cellular and molecular mechanisms not only sustains normal neuronal function and homeostasis but also influences the onset and progression of neurodegenerative diseases and other pathologies of the central nervous system.
Through a comprehensive review of the current literature and original research contributions, this Special Issue aims to explore the cellular and molecular mechanisms regulating neuronal function and homeostasis. We invite research that explores topics such as the regulation of ion channels and receptors, synaptic plasticity, cellular trafficking, neuronal metabolism, and the critical interplay between neurons and glial cells. Studies examining how alterations in these mechanisms contribute to neurodegenerative diseases, as well as those identifying potential biomarkers or therapeutic targets, are of particular interest. Submissions utilizing advanced genomic, proteomic, imaging, or electrophysiological techniques to elucidate these complex pathways are especially welcome.
By bridging the gap between basic science and clinical applications, this Special Issue aims to enhance our understanding of the cellular and molecular mechanisms regulating neuronal function, homeostasis, and neurodegeneration.
Dr. Daniel José Barbosa
Dr. Ana Filipa Sobral
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- molecular mechanisms
- cellular mechanisms
- neuronal function
- neuronal homeostasis
- neuronal health
- neuronal development
- neuronal metabolism
- neuron–glia interactions
- synaptic plasticity
- biomarkers of early diagnosis
- neurodegeneration
- brain diseases
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