Drug Development for Schizophrenia
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropharmacology and Neuropathology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 50
Special Issue Editor
Interests: multiple chemical sensitivity; anxiety; depression; new psychoactive substances; NPS; suicide; suicidality; synthetic cannabinoids; synthetic cathinones; new synthetic opioids; ketamine; esketamine; s-ketamine; obsessive–compulsive disorder (OCD); substance use disorder; drug misuse; drug abuse; drug diversion; Psychosis; substance-induced-psychosis
Special Issue Information
Dear Colleagues,
Schizophrenia is a severe and complex psychiatric disorder that affects millions of individuals worldwide. Despite significant progress in understanding its pathophysiology, the development of effective pharmacological treatments remains a critical challenge. Current antipsychotic medications primarily target dopaminergic pathways and often fail to address the full spectrum of symptoms, including cognitive deficits and negative symptoms, while also being associated with significant side effects.
This Special Issue of Brain Sciences aims to present cutting-edge research on drug development for schizophrenia. We invite authors to contribute original research articles and reviews covering a broad range of topics, including but not limited to the following: novel pharmacological targets, advancements in antipsychotic drug mechanisms, personalized medicine approaches, drug repurposing strategies, biomarkers for treatment response, neuroinflammatory and neurodevelopmental perspectives, innovative drug delivery systems, computational drug discovery, and the role of emerging compounds in schizophrenia treatment. Special emphasis will be placed on translational research that bridges the gap between basic neuroscience and clinical applications.
By gathering the latest advancements in drug development for schizophrenia, this Special Issue aims to provide insights that will enhance future therapeutic strategies and improve patient outcomes.
Dr. Alessio Mosca
Guest Editor
Manuscript Submission Information
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Keywords
- antipsychotics
- biomarkers
- glutamatergic modulation
- schizophrenia treatment
- drug discovery
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