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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Perinatal Psychiatry: Mental Health During Pregnancy and the Postpartum

edited by Saulo Gantes Tractenberg,

Thiago Wendt Viola

and Tagma Marina Schneider Donelli

submission deadline 15 Dec 2025 | Viewed by 177 | Submission Open

Keywords: perinatal; postpartum; mental health; pregnancy; postpartum depression; postpartum psychosis; psychiatric disorders; puerperal disorders; infant; perinatal care

(This special issue belongs to the Section Neuropsychiatry)

Advanced Optical Neuroimaging and Neurotransmitter Analysis in Cortical Circuits and Sensory Processing

edited by

Kurtulus Golcuk

submission deadline 15 Dec 2025 | Viewed by 85 | Submission Open

Keywords: Optical neuroimaging; Neurotransmitter dynamics; Cortical circuits; Sensory processing; Fiber Photometry; Two-Photon microscopy; Neuromodulation; Neurological disorders; Neurophysiological diseases

(This special issue belongs to the Section Systems Neuroscience)

The Microbiome in Neurological Disorders

edited by

Keehoon Lee

submission deadline 20 Dec 2025 | Viewed by 107 | Submission Open

Keywords: microbiome; brain– microbiome axis; brain– gut axis; neurological disorders; neurodegenerative; neurodevelopmental; neuroinflammatory; human microbiome

Falls: Developing, Understanding, and Communicating Effective Interventions

edited by

Shashank Ghai

submission deadline 20 Dec 2025 | Viewed by 66 | Submission Open

Keywords: gait; posture; fall prevention; balance disorders; rehabilitation; assistive technology; neurological disorders; wearable devices; intervention strategies; clinical practice; intervention communication

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Non-Antibody Based Anti-Aggregation Therapies Targeting Amyloid-Beta, Tau and Alpha-Synuclein and Other Proteins Associated With Neurodegenerative Disorders

edited by

Bruno Meloni

submission deadline 20 Dec 2025 | Viewed by 60 | Submission Open

Keywords: amyloid-beta (Aβ ) aggregation; Tau aggregation; alpha-synuclein (α -Syn) aggregation; TAR DNA-binding protein 43 (TDP-43) aggregation; superoxide dismutase (SOD1) aggregation; Huntingtin (HTT) aggregation; prion protein (PrPᶜ); protein aggregation; anti-protein aggregating agents; proteinopathies; neurodegeneration

(This special issue belongs to the Section Neurodegenerative Diseases)

Primary Progressive Aphasia: What Happens to Speech and Language? What Can We Do to Help?

edited by

Monica Lavoie

, Anna P. Volkmer, Jason D. Warren and

Petronilla Battista

submission deadline 21 Dec 2025 | Viewed by 174 | Submission Open

Keywords: primary progressive aphasia; language; brain; communication; cognition

(This special issue belongs to the Section Neurolinguistics)

Advances in Speech and Language Research for Cognitive Well-Being in Aging

edited by

Maria Teresa Carthery-Goulart

, Lilian Christine Hubner and Erica Dos Santos Rodrigues

submission deadline 21 Dec 2025 | Viewed by 47 | Submission Open

Keywords: communication skills; language abilities; speech; cognitive function; neurodegenerative diseases; neuromodulation

(This special issue belongs to the Section Neurolinguistics)

Artificial Intelligence in Neurological Disorders

edited by

Rahul Kashyap

and

Pallavi Dinesh Shirsat

submission deadline 24 Dec 2025 | Viewed by 337 | Submission Open

Keywords: artificial intelligence; neurological disorders; machine learning; deep learning; neuroimaging; Alzheimer’ s disease; Parkinson’ s disease; predictive analytics; personalized medicine; ethical AI

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Using Neuroimaging to Explore Neurodegenerative Diseases

edited by

Ting Shen

submission deadline 25 Dec 2025 | 1 articles | Viewed by 571 | Submission Open

Keywords: neuroimaging; neurodegenerative diseases; multidisciplinary research; imaging-omics study; multimodal integration; AI-driven analytics

(This special issue belongs to the Section Neurodegenerative Diseases)

Risk Factors for Tinnitus and Tinnitus-Related Disease

edited by

Alessandra Fioretti

and Alberto Eibenstein

submission deadline 25 Dec 2025 | Viewed by 326 | Submission Open

Keywords: tinnitus; anxiety; depression; stress; migraine; hearing loss; insomnia; biomarkers; noise; ototoxicity

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Brain Stimulation for Psychiatric Disorders: Emerging Evidence and New Perspectives—2nd Edition

edited by

Jacopo Lisoni

and

Stefano Barlati

submission deadline 30 Dec 2025 | 8 articles | Viewed by 7601 | Submission Open

Keywords: repetitive transcranial magnetic stimulation (rTMS) and Theta burst stimulation (TBS); transcranial electrical stimulation (tES) (transcranial direct current stimulation (tDCS); transcranial alternating current stimulation (tACS); transcranial random noise stimulation (tRNS)); magnetic seizure therapy (MST); depression; bipolar disorder; and other mood disorders; schizophrenia and psychosis; obsessive– compulsive disorder and anxiety disorders; substance use disorders; neurodevelopmental disorders (ADHD; autism); neuroimaging; neurophysiology; cognition

(This special issue belongs to the Section Neuropsychiatry)

Neural Mechanisms Underlying Sensorimotor Learning and Plasticity: Novel Advances and Future Perspectives

edited by

Giacomo Guidali

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3367 | Submission Open

Keywords: sensorimotor learning; brain plasticity; cognitive neuroscience; neurophysiology; non-invasive brain stimulation; EEG; neuromodulation; motor system; visual system; somatosensory system

(This special issue belongs to the Section Systems Neuroscience)

Cellular and Molecular Mechanisms Regulating Neuronal Function, Homeostasis, and Disease

edited by

Daniel José Barbosa

and

Ana Filipa Sobral

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2436 | Submission Open

Keywords: molecular mechanisms; cellular mechanisms; neuronal function; neuronal homeostasis; neuronal health; neuronal development; neuronal metabolism; neuron– glia interactions; synaptic plasticity; biomarkers of early diagnosis; neurodegeneration; brain diseases

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

The Future of Human–Machine Collaboration: AI in Neural Rehabilitation and Assistive Technologies

edited by

Cristian Randieri

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1109 | Submission Open

Keywords: artificial intelligence; neural rehabilitation; brain– computer interface; neuroprosthetics; machine learning; rehabilitation robotics; neuroengineering; assistive technology; wearable devices; neurosignal processing

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Advances in Psychopharmacology in Neurodevelopmental Disorders (NDDs)

edited by Shoumitro Deb

submission deadline 31 Dec 2025 | 1 articles | Viewed by 626 | Submission Open

Keywords: neurodevelopmental disorders; psychopharmacology; research; recent advances; mental health medicine

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

At the Frontiers of Neurorehabilitation: 3rd Edition

edited by

Manuel Gaviria

submission deadline 31 Dec 2025 | 1 articles | Viewed by 599 | Submission Open

Keywords: CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; optimization of clinical care; motor learning; cognitive reinforcement; motivational issues; relevant outcome measures; innovative approaches; rehabilitation devices; neuro-prosthetics; brain– computer interfaces; clinical trials for validation; regulatory issues; activities of daily living (ADLs) autonomy; quality of life; neurodevelopmental disorder

(This special issue belongs to the Section Neurorehabilitation)

Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI

edited by

Dionysus Tafiadis

, Nafsika Ziavra,

Angelos Papadopoulos

and

Konstantinos Drosos

submission deadline 31 Dec 2025 | Viewed by 282 | Submission Open

Keywords: lifespan speech and language disorders; lifespan communication disorders; special learning disabilities; lifespan voice and swallowing disorders; assessment; intervention; innovations; neuromodulation; artificial intelligence

(This special issue belongs to the Section Neurolinguistics)

Substance Abuse in the Psychiatric Population

edited by

Michael Fritz

and

Marc Fakhoury

submission deadline 31 Dec 2025 | Viewed by 267 | Submission Open

Keywords: substance abuse disorder; genetics (expression; SNPs); epigenetics; schizophrenia; forensic psychiatry; depression; bipolar disorder; translational research; personality disorders; imaging (PET; SPECT; MRI); general psychiatry

(This special issue belongs to the Section Neuropsychiatry)

Neuroscience of Learning, Mental Health, and Cultural Adaptation: Cognitive, Pedagogical, and Psychological Perspectives

edited by

Evgenia Gkintoni

Georgios Nikolaou

and

Stephanos Ph Vassilopoulos

submission deadline 31 Dec 2025 | Viewed by 195 | Submission Open

Keywords: cognitive neuroscience; mental health and learning; cultural adaptation; educational neuroscience; neuropsychology of learning; pedagogical interventions; emotional resilience in education; multicultural and inclusive education; neural mechanisms of learning; cross-cultural pedagogy

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Quantifying Motor Neurone Disease: Advances and Challenges in Developing Biomarkers, Predictive Models and Outcome Measures

edited by Roisin McMackin and

Joke De Vocht

submission deadline 31 Dec 2025 | Viewed by 177 | Submission Open

Keywords: amyotrophic lateral sclerosis; primary lateral sclerosis; progressive muscular atrophy; biomarkers (cognition; neurophysiology; biofluid markers; neuroimaging); modelling; therapeutic development; early detection and diagnosis; precision medicine

(This special issue belongs to the Section Sensory and Motor Neuroscience)

New Advances in Functional Neurosurgery—2nd Edition

edited by

Nicola Montano

submission deadline 31 Dec 2025 | Viewed by 113 | Submission Open

Keywords: functional neurosurgery; trigeminal neuralgia; microvascular decompression; deep brain stimulation; neuromodulation; spinal cord stimulation; epilepsy surgery; neurophysiological intraoperative monitoring; artificial intelligence in neurosurgery; MR-guided focused ultrasound (MRgFUS); laser interstitial thermal therapy (LiTT)

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Advanced Neuromodulation Therapies for Chronic Pain and Psychiatric Disorders

edited by

Valquíria Aparecida da Silva

and Marina de Goes Salvetti

submission deadline 31 Dec 2025 | Viewed by 44 | Submission Open

Keywords: repetitive transcranial magnetic stimulation (rTMS); theta burst stimulation (TBS); chronic pain; treatment-resistant depression; neuromodulation; tDCS; tACS; non-invasive brain stimulation; neuroplasticity; functional connectivity; major depressive disorder and generalized anxiety disorder

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Applications of Cognitive Behavioral Therapy in Mental Disorders

edited by Maria Rita Sergi

submission deadline 31 Dec 2025 | Viewed by 42 | Submission Open

Keywords: psychological well-being; psychotherapy; assessment tools; psychometric validation; clinical psychology; mental health interventions

Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders

edited by

Alexandra Susana Latini

and Ana Lucia De Paul

submission deadline 31 Dec 2025 | Viewed by 29 | Submission Open

Keywords: neurotoxicity; physiopathology; therapies; mitochondrial transplantation; oxidative stress; inflammation; mitochondrial dysfunction

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Multiple Sclerosis Across the Age Spectrum—Beyond Inflammation

edited by

Angelo Bellinvia

submission deadline 1 Jan 2026 | Viewed by 32 | Submission Open

Keywords: multiple sclerosis; neurodegeneration; disability; cognition; functional outcomes; rehabilitation; pediatric-onset; late onset; ageing

Neural Mechanisms Underlying Social Cognition and Emotional Processing

edited by

Atiqah Azhari

submission deadline 10 Jan 2026 | Viewed by 201 | Submission Open

Keywords: social cognition; emotional processing; social neuroscience; developmental neuroscience

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Deep Research into Stroke

edited by

Min Su Kim

submission deadline 15 Jan 2026 | 1 articles | Viewed by 880 | Submission Open

Keywords: stroke; rehabilitation; neuromodulation; physical therapy; robotics; artificial intelligence; neuroimaging; deep learning; machine learning; exercise

(This special issue belongs to the Section Neurorehabilitation)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Jan 2026 | Viewed by 222 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Beyond Boundaries: Current Advances in Developmental Learning Disorders

edited by Daniela Traficante and

Luisa Girelli

submission deadline 15 Jan 2026 | Viewed by 100 | Submission Open

Keywords: developmental learning disorders; transdiagnostic approach; comorbidity; domain-general components

(This special issue belongs to the Section Neuropsychology)

Inflammation and Central Nervous System

edited by

Saifudeen Ismael

submission deadline 15 Jan 2026 | Viewed by 38 | Submission Open

Keywords: inflammation; inflammasome; brain injury; neurodegeneration; aging; cognition; brain senescence

(This special issue belongs to the Section Systems Neuroscience)

Non-Invasive Neurotechnologies for Cognitive Augmentation

edited by

Caterina Cinel

Davide Valeriani

and

Saugat Bhattacharyya

submission deadline 15 Jan 2026 | Viewed by 33 | Submission Open

Keywords: neurotechnology; brain– computer interfaces; neuroergonomics; neurorehabilitation; neuroethics; brain stimulation; cognitive augmentation; cognitive enhancement; adaptive neurotechnology

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Perception Across Disciplines: Exploring the Intersections of Cognitive, Social, Affective and Neural Dimensions

edited by

Yang Zhang

submission deadline 18 Jan 2026 | 1 articles | Viewed by 594 | Submission Open

Keywords: sensory processing; cognitive systems; perception-action binding; multimodal processing; neural foundations; socio-affective systems; computational models; interdisciplinary research

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Anxiety, Depression and Stress

edited by

Sung Joon Cho

submission deadline 18 Jan 2026 | Viewed by 59 | Submission Open

Keywords: anxiety; depression; stress; NMDA modulators; brain stimulation; anti-inflammatory agents; psychosocial interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition

edited by

Daniele Corbo

submission deadline 20 Jan 2026 | 3 articles | Viewed by 5878 | Submission Open

Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Translational EEG Biomarkers in Animal Models: Bridging Pre-Clinical Findings to Human Neuroscience

edited by

Inga Griskova-Bulanova

and Cestmir Vejmola

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1232 | Submission Open

Keywords: EEG; ECoG; biomarker; animal model; pre-clinical

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in the Pharmacologic Treatment of Depression, Anxiety, and Other Psychiatric Disorders

edited by Danielle S. Cha

submission deadline 20 Jan 2026 | Viewed by 236 | Submission Open

Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease

(This special issue belongs to the Section Neuropsychiatry)

Neuropathic Pain: Pathophysiology, Diagnosis and Treatment

edited by Marcos Brioschi and

Areerat Suputtitada

submission deadline 20 Jan 2026 | Viewed by 19 | Submission Open

Keywords: neuropathic pain; pathophysiology; diagnosis; neuroimaging; thermography; artificial intelligence; treatment; rehabilitation; translational research; neuromodulation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System

edited by

Kyle Gobrogge

submission deadline 23 Jan 2026 | 2 articles | Viewed by 2445 | Submission Open

Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Emerging Trends in Youth Mental Health

edited by

Ilaria Riboldi

submission deadline 23 Jan 2026 | Viewed by 129 | Submission Open

Keywords: mental health; adolescent mental health; young adult; stress; psychological; social media; climate change; identity development; digital health; school health services

(This special issue belongs to the Section Neuropsychology)

Assessment and Rehabilitation of Cognitive Function in Neurological Disorders

edited by Gilles Naeije

submission deadline 25 Jan 2026 | 1 articles | Viewed by 457 | Submission Open

Keywords: post-stroke cognitive impairment; diaschisis; cerebellum; cortico-cerebellar connectivity; neuromodulation; transcranial cerebellar stimulation; cognitive rehabilitation; functional connectivity

(This special issue belongs to the Section Neurorehabilitation)

Advances in Neurofeedback Research

edited by

Eddy J. Davelaar

submission deadline 25 Jan 2026 | Viewed by 73 | Submission Open

Keywords: neurofeedback; brain– computer interface; neurophenomenology; EEG; rt-fMRI; fNIRS-neurofeedback

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Current Research in Neurosurgery

edited by

Roberto Altieri

, Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque

submission deadline 30 Jan 2026 | 6 articles | Viewed by 5184 | Submission Open

Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Brain Tumors: From Molecular Basis to Therapy

edited by Paolo Tini and Giuseppe Minniti

submission deadline 30 Jan 2026 | 5 articles | Viewed by 4953 | Submission Open

Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance

(This special issue belongs to the Section Neuro-oncology)

Advances in the Relationship Among Brain, Physical Function, and Exercise Performance

edited by

Luca Petrigna

submission deadline 30 Jan 2026 | 1 articles | Viewed by 751 | Submission Open

Keywords: physical performance; dual task; cognition; sport; environment; cerebellum; movement; neurodegenerative disease

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Management of Acute Stroke

edited by Ali Hammed and

Christian Tanislav

submission deadline 30 Jan 2026 | Viewed by 12 | Submission Open

Keywords: management in acute stroke care; thrombolysis; mechanical thrombectomy; epidemiology in stroke care; stroke unit; cerebral infarction; intracranial bleeding; therapy in acute stroke

(This special issue belongs to the Section Systems Neuroscience)

Advances in Memory and Cognitive Decline Associated with Aging and Alzheimer's Disease

edited by

Pavan Kumar

submission deadline 31 Jan 2026 | 7 articles | Viewed by 9954 | Submission Open

Keywords: neurodegeneration; neuroprotection; neurogenesis; learning and memory; engram; neuro-vascular

(This special issue belongs to the Section Neurodegenerative Diseases)

The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life

edited by

Giuseppe Barbato

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9521 | Submission Open

Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Advanced Clinical Diagnosis, Evaluation, and Treatment of Psychosis

edited by Giulia Menculini and

Gaia Sampogna

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8235 | Submission Open

Keywords: psychotic disorders; affective psychoses; schizophrenia; antipsychotic drugs; psychosocial treatments; at-risk mental states; biomarkers; early intervention; prevention; social psychiatry

(This special issue belongs to the Section Neuropsychiatry)

The Eye as the Window to Brain Science: Fields of Neuroscience Created from Eye Research

edited by

George Ayoub

submission deadline 31 Jan 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: sensory system functions; neuroanatomy; neurochemistry; neurophysiology; developmental neurobiology; neurological health and disease

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in the Diagnosis, Visualization and Treatment of Intracranial Aneurysms and Subarachnoid Hemorrhage

edited by

Serge Marbacher

and Lukas Andereggen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 452 | Submission Open

Keywords: neurovascular; intracranial aneurysm; subarachnoid hemorrhage; education and teaching; imaging technology; hybrid operating room; augmented reality; cerebrovascular disease; cost-effectiveness; artificial intelligence

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Displaying special issue 151-200 on page 4 of 6.

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