Deep Brain Stimulation (DBS)—Current Status and Future Directions
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 9
Special Issue Editor
Special Issue Information
Dear Colleagues,
Deep brain stimulation (DBS) has emerged as a groundbreaking neuromodulation therapy, employing implanted electrodes to deliver targeted electrical impulses to the brain and offering clinical improvements in disease-related symptoms of neurological and neuropsychiatric disorders. For this Special Issue, we invite high-quality contributions on the latest technological and clinical advances in DBS, including adaptive closed-loop systems that optimize stimulation parameters in real time via neural biomarkers, innovations in directional leads and multi-contact electrode arrays to refine targeting precision and minimize side effects, and explorations of novel indications, such as for depression, obsessive–compulsive disorder, and Alzheimer’s disease. We also encourage research on biocompatible materials for long-term stability, artificial intelligence-driven personalization algorithms, and minimally invasive delivery methods, such as MRI-guided electrode placement. All article types—original studies, brief communications, opinion pieces, systematic reviews, and meta-analyses—are welcome. Join us in expanding and refining the therapeutic scope of DBS.
Dr. Yousef Salimpour
Guest Editor
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Keywords
- deep brain stimulation
- neuromodulation
- adaptive closed-loop systems
- directional leads
- neural biomarkers artificial intelligence
- personalization treatment
- biocompatible materials
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