Advances in Parkinson’s Disease

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".

Deadline for manuscript submissions: 15 August 2026 | Viewed by 45

Special Issue Editor


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Guest Editor
Biomedical Engineering and Kinesiology, California State University San Marcos, 333 S. Twin Oaks Valley Rd., San Marcos, CA 92096, USA
Interests: applied mathematics; neuroscience; motor control; heart–brain and brain–muscle coherence; transcranial direct current stimulation (tDCS neuromodulation)
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Special Issue Information

Dear Colleagues,

Parkinson’s disease (PD) is one of the most challenging neurodegenerative disorders, marked by a complex interplay of motor, cognitive, and autonomic impairments that evolve over years. Since its earliest clinical descriptions, research on PD has expanded from characterizing motor symptoms to mapping the neural circuits, biochemical pathways, and systemic alterations that drive disease progression. In recent decades, transformative developments have occurred in high-resolution neural recording, wearable sensing, advanced neuroimaging, and computational tools capable of identifying subtle physiological signatures long before overt symptoms emerge.

This Special Issue, titled “Advances in Parkinson’s Disease”, aims to bring together cutting-edge research spanning basic mechanisms, translational discoveries, and emerging therapeutic strategies. We seek contributions that deepen our mechanistic understanding, ranging from synaptic dysfunction and network-level changes to alterations in motor variability, neuromuscular synchronization, and sensorimotor integration. Studies employing machine learning, quantitative signal analysis, digital biomarkers, neuromodulation, and innovative clinical trial designs are particularly encouraged.

We invite original research, comprehensive reviews, and methodological advances that move the field toward earlier diagnosis, individualized treatment, and improved quality of life for individuals with PD. By assembling diverse perspectives from neuroscience, engineering, rehabilitation, and clinical practice, this Special Issue aims to highlight the most promising avenues shaping the future of PD research and care.

Dr. Osmar Pinto Neto
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Parkinson’s disease
  • neurodegeneration
  • motor control
  • digital biomarkers
  • sensorimotor integration
  • neuromuscular physiology
  • machine learning and signal analysis
  • early diagnosis
  • neuromodulation
  • translational neuroscience

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Published Papers

This special issue is now open for submission.
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