Innovations in Skull Base Surgery

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurosurgery and Neuroanatomy".

Deadline for manuscript submissions: 29 August 2026 | Viewed by 875

Special Issue Editor


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Guest Editor
Department of Neurological Surgery, Nippon Medical School Hospital, Tokyo 113-8603, Japan
Interests: skull base tumor; cerebrovascular surgery; endoscopic

Special Issue Information

Dear Colleagues,

Recent advances in skull base and cerebrovascular surgery have been driven by the development of microsurgical, endoscopic, and exoscopic techniques that enable surgeons to address complex lesions with greater precision and safety. The evolution of visualization technologies, including high-definition systems and head-mounted displays, has further expanded the possibilities of minimally invasive neurosurgery, reducing surgical morbidity and improving ergonomic efficiency. At the same time, new approaches in perioperative management and translational research, such as studies on moyamoya disease, intracranial aneurysms, and RNF213-related vasculopathies, continue to broaden our understanding of cerebrovascular pathophysiology. This Special Issue aims to highlight innovations in skull base and vascular neurosurgery, focusing on surgical strategies, technical refinements, and minimally invasive solutions.

We welcome original research, clinical reports, technical notes, and reviews that provide new insights into surgical practice, patient outcomes, and the future directions of neurosurgery.

Dr. Fumihiro Matano
Guest Editor

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Keywords

  • microsurgery
  • endoscopic skull base surgery
  • exoscopic surgery
  • minimally invasive neurosurgery
  • skull base and cerebrovascular surgery
  • intracranial aneurysm
  • moyamoya disease
  • RNF213

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Published Papers (1 paper)

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Research

13 pages, 4077 KB  
Article
Redefining Access to the Mesiotemporal Lobe: The Transplanum Polare Approach with Cadaveric and Operative Video Demonstration
by Jesse Shamsul, Alessandro Pesaresi, Daniele Starnoni, Samia Messaoudi, Lorenzo Dolci, Hugues Cadas, Sami Schranz, Sara Sabatasso, Vincent Dunet, Roy T. Daniel, Pablo González-López and Lorenzo Giammattei
Brain Sci. 2026, 16(4), 351; https://doi.org/10.3390/brainsci16040351 - 25 Mar 2026
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Abstract
Objectives: This study aims to define the surgical anatomy, technical feasibility, advantages, and limitations of the TPPA through detailed cadaveric dissection and a representative clinical case, evaluating its potential as a safe and effective alternative to traditional approaches to the mesiotemporal lobe. Methods: [...] Read more.
Objectives: This study aims to define the surgical anatomy, technical feasibility, advantages, and limitations of the TPPA through detailed cadaveric dissection and a representative clinical case, evaluating its potential as a safe and effective alternative to traditional approaches to the mesiotemporal lobe. Methods: A cadaveric dissection was performed on one adult head injected with colored latex, using standard microsurgical instruments and high-definition video documentation. Each procedural step was recorded and illustrated with cadaveric photographs. Additionally, a clinical case of mesiotemporal cavernous hemangioma resected via TPPA is presented, including an operative video. Results: The dissection demonstrated a direct and safe trajectory to the amygdala and hippocampal head, with clear identification of key vascular and white matter landmarks. In the clinical case, the lesion was completely resected with no postoperative neurological deficits. Conclusions: The TPPA represents a novel microsurgical corridor to the mesiotemporal region, minimizing cortical disruption, Sylvian fissure dissection, and manipulation of middle cerebral artery branches. Although its exposure is limited posteriorly, the TPPA could offer an optimal balance between functional preservation and surgical accessibility, constituting a valuable addition to the modern microsurgical armamentarium. Full article
(This article belongs to the Special Issue Innovations in Skull Base Surgery)
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