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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements and Future Directions in Clinical Psychosis

edited by

Marco Colizzi

and

Alessandra Martinelli

submission deadline 10 Feb 2026 | 1 articles | Viewed by 1714 | Submission Open

Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innovative diagnostic tools

Novel Insights into Developmental Coordination Disorder

edited by Rita C Silveira and

Renato S. Procianoy

submission deadline 10 Feb 2026 | 1 articles | Viewed by 479 | Submission Open

Keywords: neurodevelopment; prematurity; developmental coordination disorder (DCD); executive function; life-course trajectories; mental health; brain development

(This special issue belongs to the Section Developmental Neuroscience)

Somatosensory Evoked Potentials: Beyond Somesthesis

edited by Ana Maria Cebolla and Guy Cheron

submission deadline 15 Feb 2026 | 1 articles | Viewed by 498 | Submission Open

Keywords: somatosensory evoked potentials; EEG; brain oscillations; movement; gating; modified consciousness states; motor learning

(This special issue belongs to the Section Systems Neuroscience)

Neuropathic Pain: From Physiopathology to Improvements in Diagnosis and Management

edited by Caren Tatiane De David Antoniazzi and Patricia Rodrigues

submission deadline 15 Feb 2026 | Viewed by 202 | Submission Open

Keywords: neuropathic pain; pain mechanisms; neuroinflammation; sensitization; biomarkers; chronic pain; somatosensory system; pain diagnosis; personalized medicine; pain management

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Critical Issues in Motor Control and Sensory–Motor Integration

edited by Simone Gill

submission deadline 15 Feb 2026 | Viewed by 172 | Submission Open

Keywords: motor control; sensorimotor; multisensory; human movement

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Migraine Management: Exploring Neural Clues

edited by Soma Sahai-Srivastava

submission deadline 15 Feb 2026 | Viewed by 85 | Submission Open

Keywords: migraine management; translational research; non-drug treatment; neural cues; non-pharmacological treatment

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Role of Glia in Inflammatory Processes

edited by

Charles Elias Assmann

and Margarete Dulce Bagatini

submission deadline 16 Feb 2026 | 4 articles | Viewed by 6165 | Submission Open

Keywords: neuroinflammation; neurodegenerative and psychiatric disorders; microglia; astrocytes; purinergic signaling; bioactive and natural compounds; immunopharmacology and immunotoxicology; oxidative and nitrosative stress; neuroimaging; neuroscience and behavior

(This special issue belongs to the Section Neuroglia)

Language, Communication and the Brain—2nd Edition

edited by

Jayanthi Sasisekaran

submission deadline 20 Feb 2026 | 4 articles | Viewed by 5768 | Submission Open

Keywords: cognitive; attention; working memory; executive functions; linguistic; language planning; speech production; fluency; sensorimotor; hearing; speech and language production; neurotypical; neurodiverse; autism; apraxia; dysarthria; stuttering; speech sound disorders; artificial intelligence; data science; theoretical; data-driven

(This special issue belongs to the Section Neurolinguistics)

Advanced Technologies and Approaches for Understanding and Treating Psychological Disorders

edited by

Alessandra Vergallito

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3708 | Submission Open

Keywords: psychological disorders; psychological well-being; psychological interventions; non-invasive brain stimulation; digital therapies; artificial intelligence; virtual reality; pharmacological interventions

(This special issue belongs to the Section Neuropsychiatry)

Advances in Cerebral Aneurysm Surgery: The Latest Technologies and Techniques

edited by Andreas Gruber

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1261 | Submission Open

Keywords: microsurgical aneurysm clipping; preoperative simulation; hybrid neurovascular surgery; skills-lab training; intraoperative monitoring and imaging

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Non-Invasive Neural Technology in Analysing Spinal Cord Activity

edited by

Giulio Gabrieli

submission deadline 20 Feb 2026 | Viewed by 84 | Submission Open

Keywords: spinal cord; non-invasive recording; electrophysiology; neurotechnology; signal processing; artifact reduction; wearable sensors; machine learning

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Cognitive Training in Health and Disease

edited by

María del Carmen Carcelén-Fraile

submission deadline 22 Feb 2026 | Viewed by 111 | Submission Open

Keywords: cognitive training; child development; adolescence; executive functions; cognitive stimulation; mental health; neurodevelopmental disorders; healthy aging; education and cognition

(This special issue belongs to the Section Cognitive Neuroscience)

Eye-Tracking Monitoring of Neurological and Psychiatric Conditions Across Life Span

edited by

Marco Cavallo

and

Juan Esteban Kamienkowski

submission deadline 23 Feb 2026 | 3 articles | Viewed by 7833 | Submission Open

Keywords: gaze patterns; eye tracking; mild cognitive impairment; multiple sclerosis; neurodevelopmental disorders; saccades

(This special issue belongs to the Section Behavioral Neuroscience)

Current Advances in Developmental Dyslexia

edited by

John F. Stein

submission deadline 25 Feb 2026 | 1 articles | Viewed by 768 | Submission Open

Keywords: developmental dyslexia; neuroimaging; neuropsychology; molecular genetics

(This special issue belongs to the Section Neurolinguistics)

Advances in Pediatric Neurological Disease Research

edited by Milena La Spina and

Silvia Marino

submission deadline 25 Feb 2026 | 1 articles | Viewed by 438 | Submission Open

Keywords: non-invasive ventilation; ultrasound; epilepsy; CNS infection; neuro-oncology; genetic disease; sindromology; polysomnography

(This special issue belongs to the Section Developmental Neuroscience)

Prenatal and Perinatal Risk Factors for Autism

edited by Gary Steinman

submission deadline 25 Feb 2026 | Viewed by 104 | Submission Open

Keywords: perinatal period; prenatal infection; children born preterm; pregnancy; autism

(This special issue belongs to the Section Developmental Neuroscience)

Lucid Dreaming and Psychophysiological Correlates of States of Consciousness

edited by

Daniel Erlacher

and Clarita Bonamino

submission deadline 27 Feb 2026 | 1 articles | Viewed by 2040 | Submission Open

Keywords: lucid dreaming; states of consciousness; REM sleep; metacognition; dream phenomenology; volitional control

(This special issue belongs to the Section Neuropsychology)

Mental Images and the Brain: From Cognitive Neuropsychology to Functional Neuroimaging

edited by

Anna Maria Berardi

submission deadline 27 Feb 2026 | Viewed by 124 | Submission Open

Keywords: mental imagery; visual perception; dorsal visual stream; ventral visual stream; object; spatial; brain lesion; functional brain imaging; aphantasia; hyperphantasia

(This special issue belongs to the Section Neuropsychology)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Feb 2026 | 1 articles | Viewed by 8003 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6842 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Non-Invasive Brain Stimulation for Brain Disorders

edited by

Giovanni Cirillo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1568 | Submission Open

Keywords: TMS; tCS; NIBS; plasticity; CNS; neurological disorders; psychiatric disorders

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Assessment and Training of Perceptual-Motor Performance (2nd Edition)

edited by

Gary Wilkerson

and

Scott L. Bruce

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1077 | Submission Open

Keywords: perception; cognition; motor control; neural efficiency; traumatic brain injury; neurodegeneration; psycho-affective disorder

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Novel Techniques in Spine Neurosurgery

edited by Maurizio Fornari,

Cesare Faldini

and Gabriele Capo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 861 | Submission Open

Keywords: spine neurosurgery; minimally invasive spine surgery; spinal endoscopy; robotic-assisted spine surgery; spinal navigation; augmented reality in neurosurgery; biologics and spinal fusion; neuromodulation; novel surgical techniques; technological innovation in spine surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Cellular and Molecular Mechanisms Underlying Aging Progression

edited by

Mateus Vidigal de Castro

submission deadline 28 Feb 2026 | 1 articles | Viewed by 433 | Submission Open

Keywords: neuroaging ; neurodegeneration ; iPSC-derived models ; omics technologies ; cellular senescence ; neuroinflammation ; longevity

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 28 Feb 2026 | Viewed by 286 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Advances in Neuroinflammation and Immune Response

edited by Bojan Shutinoski

submission deadline 28 Feb 2026 | Viewed by 170 | Submission Open

Keywords: neuroinflammation; immune response; glial cells; blood– brain barrier; neurodegenerative diseases

(This special issue belongs to the Section Systems Neuroscience)

Anxiety and Mood Disorders: Novel Research on Mechanisms, Diagnosis, and Treatment

edited by

Zuleide Maria Ignácio

submission deadline 28 Feb 2026 | Viewed by 103 | Submission Open

Keywords: anxiety disorders; mood disorders; neurotransmission; genetic and epigenetic mechanisms; therapeutic strategies; pharmacological targets; cellular circuits and signaling; neuronal plasticity; inflammation; oxidative stress

(This special issue belongs to the Section Neuropsychiatry)

Risks and Mechanisms in Addiction Neuroscience Informing Treatment

edited by Amy A. Herrold

submission deadline 7 Mar 2026 | Viewed by 278 | Submission Open

Keywords: substance use disorders; risk; mechanism; neuromodulation; psychedelic; GLP-1

(This special issue belongs to the Section Neuropsychiatry)

Application of Invasive and Non-Invasive Brain Stimulation Techniques in Neurological Disorders

edited by Vincenzo Levi and

Massimo Marano

submission deadline 10 Mar 2026 | 2 articles | Viewed by 1831 | Submission Open

Keywords: deep brain stimulation (DBS); magnetic resonance-guided focused ultrasound (MRgFUS); transcranial magnetic stimulation (TMS); transcranial direct-current stimulation (tDCS); vagus nerve stimulation (VNS); brain– machine interface; brain stimulation; non-invasive brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Unraveling the Role of Physical Activity in Brain, Cognition, and Mental Health

edited by

Fiorenzo Moscatelli

, Nicola Mancini and Pompilio Cusano

submission deadline 15 Mar 2026 | 4 articles | Viewed by 17004 | Submission Open

Keywords: physical activity; brain health; cognition; mental health; neurogenesis; neuroplasticity; cognitive function; exercise; depression; anxiety

(This special issue belongs to the Section Neuropsychiatry)

Current Basic and Clinical Approaches in Neurodegenerative Diseases: Diagnostics and Therapeutics

edited by

Genaro G. Ortiz

and Gloria A. Benítez-King

submission deadline 15 Mar 2026 | 3 articles | Viewed by 14254 | Submission Open

Keywords: neurodegenerative diseases; advances; diagnosis; treatment; basic clinical approach; treatment protocols

(This special issue belongs to the Section Neurodegenerative Diseases)

Neuropeptides, Behavior and Psychiatric Disorders

edited by Chanpreet Singh and Jin Xu

submission deadline 15 Mar 2026 | 2 articles | Viewed by 2836 | Submission Open

Keywords: neuropeptides; psychiatric disorders; behavioral neuroscience; neuromodulation; stress and emotion; neurocircuitry; translational psychiatry; biomarkers; optogenetics; peptidergic signaling

(This special issue belongs to the Section Behavioral Neuroscience)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 Mar 2026 | 1 articles | Viewed by 2685 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Spinal Cord Injury: Biomarkers, Neuroimaging and Therapeutic Approaches

edited by

Alaa Abd-Elsayed

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1565 | Submission Open

Keywords: spinal cord; injury; neuromodulation; surgery; injury; innovations

(This special issue belongs to the Section Neurorehabilitation)

EEG and fMRI Applications in Exploring Brain Activity

edited by

Nicoletta Cera

and Faustino Ricardo

submission deadline 15 Mar 2026 | 1 articles | Viewed by 764 | Submission Open

Keywords: fMRI; EEG; resting state; data-driven analysis; machine learning; emotion; cognitive functions; aging; multimodal imaging

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Concussions

edited by

Neil Heron

submission deadline 15 Mar 2026 | Viewed by 62 | Submission Open

Keywords: concussion; mild traumatic brain injury; systematic review; concussion biomarkers; clinical trials; public health

(This special issue belongs to the Section Systems Neuroscience)

Neuromorphic Artificial Intelligence and Its Applications: Retrospective and Prospective

edited by Vassilis Cutsuridis

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4374 | Submission Open

Keywords: neuromorphic artificial intelligence; deep learning; sensory recognition; cognitive function; cognitive robotics; neuroimaging

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Clinical Research on Neurological Rehabilitation After Stroke

edited by

Myoung-Kwon Kim

submission deadline 20 Mar 2026 | 1 articles | Viewed by 4070 | Submission Open

Keywords: stroke rehabilitation; neurological recovery; physical therapy; cognitive rehabilitation; neuroplasticity; functional outcomes; assistive technology; virtual reality therapy; Parkinson’ s disease rehabilitation

(This special issue belongs to the Section Neurorehabilitation)

The Olfactory System in Health and Disease

edited by David M. Coppola

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1367 | Submission Open

Keywords: Alzheimer’ s; Parkinson’ s; Huntington’ s; MS; depression; anxiety; disorder; olfactory bulbectomy; anosmia; smell; limbic system

(This special issue belongs to the Section Systems Neuroscience)

The Role of Multimodal Imaging in Assessing the Biology and Staging of Neurodegenerative Disorders

edited by

Andrea Varrone

submission deadline 20 Mar 2026 | 1 articles | Viewed by 745 | Submission Open

Keywords: amyloid beta; phosphorylated tau; alpha-synuclein; neuronal loss; neuromelanin; iron content; cardiac denervation; dopaminergic cell loss

(This special issue belongs to the Section Neurodegenerative Diseases)

Cellular and Molecular Mechanisms of Neuropathic Pain

edited by

Al-Khrasani Mahmoud

submission deadline 20 Mar 2026 | 1 articles | Viewed by 268 | Submission Open

Keywords: neuropathic pain; mechanisms; novel targets; natural drugs; novel synthetic and semi-synthetic drugs; monoclonal antibodies

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Advances in Rehabilitation Strategies for Traumatic Brain Injury

edited by

Jennifer V. Wethe

submission deadline 20 Mar 2026 | Viewed by 141 | Submission Open

Keywords: traumatic brain injury; neurorehabilitation; neuroplasticity; cognitive rehabilitation; virtual reality; community reintegration; tele-rehabilitation; neurostimulation; translational research; individualized intervention

(This special issue belongs to the Section Neurorehabilitation)

Neurobehavioral Mechanisms of Learning and Adaptation: Translational Perspectives from Basic to Applied Science

edited by John Michael Falligant and

Rusty Nall

submission deadline 20 Mar 2026 | Viewed by 139 | Submission Open

Keywords: behavioral neuroscience; experimental analysis of behavior; computational behavior analysis; quantitative modeling; reinforcement learning; translational research; behavioral pharmacology; neurobehavioral mechanisms of learning; persistence and relapse; behavioral phenotyping

(This special issue belongs to the Section Behavioral Neuroscience)

Inflammation, Stress, and Comorbidity in Psychiatry: Mechanisms and Therapeutic Implications

edited by Heline Mirzakhanian

submission deadline 20 Mar 2026 | Viewed by 87 | Submission Open

Keywords: immune biomarkers in psychiatry; neuroinflammation; precision neuropsychiatry; risk mechanisms; comorbidity models; HPA axis dysregulation; anti-inflammatory treatments; psychiatric and physical comorbidity; cytokine signaling; microglial activation

(This special issue belongs to the Section Neuropsychiatry)

Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 85 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Neural Correlates of Cognitive Workload and Learning: Portable Brain Monitoring During Skill Acquisition and Real-World Task Performance

edited by Adrian Curtin, Sebastien Scannella,

Hasan Ayaz

and

Candida Barreto

submission deadline 25 Mar 2026 | 1 articles | Viewed by 647 | Submission Open

Keywords: portable neuroimaging; wearable brain sensing; skill acquisition; expertise development; motor learning; cognitive workload; fNIRS/EEG applications; neural efficiency; closed-loop training; neurostimulation (tDCS/rTMS/FUS)

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Balance: Multisensory Integration and Rehabilitation Approaches

edited by

Min-wook Kim

submission deadline 25 Mar 2026 | Viewed by 170 | Submission Open

Keywords: multisensory integration; balance and gait disorders; vestibular; visual; and somatosensory assessment; postural control; sensorimotor dysfunction; neurodegenerative diseases (e.g.; Parkinson’ s; PSP); stroke and brain injury; motor rehabilitation; virtual and augmented reality; neuroplasticity; fall risk and prevention; wearable technology and kinematic analysis

(This special issue belongs to the Section Neurodegenerative Diseases)

Language Perception and Processing

edited by

Ratree Wayland

submission deadline 27 Mar 2026 | 6 articles | Viewed by 6620 | Submission Open

Keywords: language; cognitive mechanism; neural mechanism; speech; perception; processing

(This special issue belongs to the Section Neurolinguistics)

Neuropsychological Exploration of Spatial Cognition and Navigation

edited by

Jose Manuel Cimadevilla

Laura Piccardi

Raffaella Nori

Maria Kozhevnikov

and Sean Commins

submission deadline 27 Mar 2026 | 4 articles | Viewed by 3879 | Submission Open

Keywords: spatial memory; neuropsychological; spatial navigation; cognitive disorder; Alzheimer’ s disease; spatial cognition; dementia; brain Function

(This special issue belongs to the Section Neuropsychology)

Palliative Care for Patients with Severe Neurological Impairment

edited by

Giovanna Artioli

and

Federica Dellafiore

submission deadline 30 Mar 2026 | 4 articles | Viewed by 5154 | Submission Open

Keywords: severe neurological impairment; neurological chronic disease; palliative care; early palliative care; nursing competencies; advance care planning; caregiver support; mental Illness of Healthcare professionals; non pharmacological and complementary treatment; bio-psyco-social and existential needs of patient and caregiver

(This special issue belongs to the Section Neurorehabilitation)

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