Advances in Neuroinflammation and Immune Response
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 6
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue, “Advances in Neuroinflammation and Immune Response” in Brain Sciences, highlights cutting-edge research focused on the complex interplay between the immune system and central nervous system (CNS). Neuroinflammation, once considered a bystander effect of neural injury, is now recognized as a critical driver of numerous neurological disorders, including Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and psychiatric conditions such as depression and schizophrenia.
This Special Issue brings together original research articles and comprehensive reviews that explore the mechanisms underlying CNS immune activation, the role of glial cells, blood–brain barrier dysfunction, and emerging neuroimmune pathways. Emphasis is placed on novel biomarkers, therapeutic targets, and the translational potential of immunomodulatory strategies. Studies employing advanced techniques such as single-cell sequencing, in vivo imaging, and systems biology contribute to a deeper understanding of the dynamic immune responses within the brain.
By fostering interdisciplinary collaboration across immunology, neuroscience, and clinical research, this Special Issue aims to fill knowledge gaps and promote the development of targeted therapies for neuroinflammatory conditions. Collectively, the contributions offer valuable insights into how immune dysregulation contributes to CNS pathology and how restoring immune balance could transform the treatment of neurological diseases.
Dr. Bojan Shutinoski
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuroinflammation
- immune response
- glial cells
- blood–brain barrier
- neurodegenerative diseases
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