Migraine Management: Exploring Neural Clues
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropharmacology and Neuropathology".
Deadline for manuscript submissions: closed (15 February 2026) | Viewed by 1693
Special Issue Editor
Special Issue Information
Dear Colleagues,
Migraine is the second most disabling neurological disorder that affects over one billion people globally. Once considered primarily vascular, migraine is a complex neurovascular disorder involving both cortical and subcortical pathways. Recent advances have uncovered early neural cues, such as hypothalamic activation, abnormal thalamocortical processing, role of inflammation and mast cell activation, thus offering new targets for intervention.
This Special Issue explores cutting-edge research into the neural mechanisms, biomarkers, and multidimensional therapies transforming migraine care. We highlight translational research and advances in pharmacological management, but also non-pharmacological treatments such as neuromodulation, wearable neurotech, and AI-based forecasting tools, behavioral therapies—such as cognitive behavioral therapy (CBT), biofeedback, and relaxation training—and structured trigger management, which remain foundational in preventing migraine chronification. The integration of neural insights with behavioral and technological interventions marks a new era in personalized migraine care.
We invite contributions that bridge translational neuroscience with clinical application, highlighting novel diagnostic and therapeutic ideas along with non-drug pathophysiological-targeted treatment strategies highlighting the complex neural inputs and outputs of the migraine brain. We encourage submission of the following paper types: original papers, systematic reviews, short reports, clinical trials, perspectives, communications, etc.
Dr. Soma Sahai-Srivastava
Guest Editor
Manuscript Submission Information
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Keywords
- migraine management
- translational research
- non-drug treatment
- neural cues
- non-pharmacological treatment
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