Cellular and Molecular Mechanisms of Neuropathic Pain
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Sensory and Motor Neuroscience".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 12
Special Issue Editor
Interests: in vitro and vivo opioid pharmacology; in vitro pharmacology and applied biochemistry (isolated organs, brain slices, calcium imaging)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuropathic pain is a significant condition that impairs individuals' ability to fulfill their professional responsibilities, negatively impacting societal economic well-being. It arises from damage and/or diseases affecting the somatosensory system at peripheral, central, or both levels, leading to various morphological and neurochemical changes in pain processing pathways. The neurochemical alterations associated with neuropathic pain involve an imbalance of neurotransmitters responsible for pain modulation, resulting in both inhibitory and excitatory patterns. These changes complicate the experience of pain and challenge the efficacy of traditional therapies.
In this Special Issue, we invite papers and reviews that explore the mechanisms underlying neuropathic pain, particularly research focused on restoring the balance between the excitatory and inhibitory systems involved in pain sensation. We also encourage contributions investigating novel therapeutic targets and innovative pharmacological approaches—whether natural or synthetic—that show promise for managing this complex condition.
Your research is crucial for enhancing our understanding of neuropathic pain and improving treatment options for affected individuals.
Prof. Dr. Al-Khrasani Mahmoud
Guest Editor
Manuscript Submission Information
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Keywords
- neuropathic pain
- mechanisms
- novel targets
- natural drugs
- novel synthetic and semi-synthetic drugs
- monoclonal antibodies
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