Adult Neurogenesis and Cognitive Function
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 64
Special Issue Editor
Interests: Alzheimer's disease; memory; neurogenesis; aging; neurodegeneration; neuroinflammation; cognition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurogenesis, the process of generating new neurons, which has intrigued brain researchers for years, begins during early development and is confined to specific brain regions in adulthood. The primary neurogenesis process occurs during development, resulting in the formation of neuronal arrangements in various brain regions, each with a distinct functional role. These brain cells gradually deteriorate as individuals age, with some regions being more susceptible to this process; however, neurodegenerative diseases significantly accelerate neuronal loss. Adult neurogenesis has been observed in the subventricular zone and subgranular zone of the dentate gyrus of the hippocampus, a crucial region involved in learning and memory, in rodents, primates, and humans. Nevertheless, adult human neurogenesis remains a contentious topic within the neuroscience community. Compared to rodents, the human dentate gyrus produces fewer adult-born cells, and the survival and integration of these cells into circuitry remain unanswered questions. Despite these challenges, researchers worldwide have reported neurogenesis in older individuals, including superagers aged 70-80 and older. These newly matured neurons contribute significantly to their cognitive function.
We invite to our Special Issue research articles that explore adult neurogenesis, its impact on various neurodegenerative diseases and neuropsychiatric disorders, and the role it plays in learning and memory.
Dr. Pavan Kumar
Guest Editor
Manuscript Submission Information
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Keywords
- neurogenesis
- learning and memory
- neurodegeneration
- Alzheimer’s
- neuropsychiatric disorders
- cognition
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