Biosensors 2025, 15(11), 754; https://doi.org/10.3390/bios15110754 - 11 Nov 2025
Abstract
Nanotechnology offers powerful new tools to enhance food quality monitoring and safety assurance. In the food industry, nanoscale materials (e.g., metal, metal oxide, carbon, and polymeric nanomaterials) are being integrated into sensory systems to detect spoilage, contamination, and intentional food tampering with unprecedented
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Nanotechnology offers powerful new tools to enhance food quality monitoring and safety assurance. In the food industry, nanoscale materials (e.g., metal, metal oxide, carbon, and polymeric nanomaterials) are being integrated into sensory systems to detect spoilage, contamination, and intentional food tampering with unprecedented sensitivity. Nanosensors can rapidly identify foodborne pathogens, toxins, and chemical changes that signal spoilage, overcoming the limitations of conventional assays that are often slow, costly, or require expert operation. These advances translate into improved food safety and extended shelf-life by allowing early intervention (for example, via antimicrobial nano-coatings) to prevent spoilage. This review provides a comprehensive overview of the types of nanomaterials used in food sensory applications and their mechanisms of action. We examine current applications in detecting food spoilage indicators and adulterants, as well as recent innovations in smart packaging and continuous freshness monitoring. The advantages of nanomaterials—including heightened analytical sensitivity, specificity, and the ability to combine sensing with active preservative functions—are highlighted alongside important toxicological and regulatory considerations. Overall, nanomaterials are driving the development of smarter food packaging and sensor systems that promise safer foods, reduced waste, and empowered consumers. However, realizing this potential will require addressing safety concerns and establishing clear regulations to ensure responsible deployment of nano-enabled food sensing technologies. Representative figures of merit include Au/AgNP melamine tests with LOD 0.04–0.07 mg L−1 and minute-scale readout, a smartphone Au@carbon-QD assay with LOD 3.6 nM, Fe3O4/DPV detection of Sudan I at 0.001 µM (linear 0.01–20 µM), and a reusable Au–Fe3O4 piezo-electrochemical immunosensor for aflatoxin B1 with LOD 0.07 ng mL−1 (≈15 × reuse), alongside freshness labels that track TVB-N/amine in near-real time and e-nose arrays distinguishing spoilage stages.
Full article
(This article belongs to the Section Environmental Biosensors and Biosensing)
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