Advanced Materials for Electrochemical Sensors and Biosensors Development—2nd Edition

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 1195

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Guest Editor
MiCRA Biodiagnostics Technology Gateway and Health, Engineering and Material Sciences (HEMS) Hub, Technological University Dublin (TU Dublin), D24 FKT9 Dublin, Ireland
Interests: electrochemical sensors and biosensors; agri-food and diagnostic microbiology; immunoassay development; biomarkers detection and point-of-care devices; nanomaterials and antimicrobial resistance (AMR)
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Special Issue Information

Dear Colleagues,

Electrochemical methods and electroanalytical techniques are promising next-generation analytical tools for various sensing and biosensing applications owing to their exceptional characteristics and advantages over conventional analytical techniques. Electroanalytical techniques are rapid, cost-effective and user-friendly, capable of sensitive and selective measurements, and compatible for miniaturization and out-of-laboratory applications, thereby providing exciting prospects for various fields. Electrochemical approaches can be applied for bioanalysis (e.g., glucose sensing, antigen/antibody or biomarker detection, etc.) as well as for non-biological contaminant analysis (e.g., in agri-food, water and environmental analysis, etc.).

An electrochemical sensor transforms electrochemical information into an analytically useful signal, and is usually composed of two basic components: a chemical (molecular) recognition system and a physicochemical transducer. This device converts chemical reaction into a signal that can be detected via electroanalytical techniques. Biosensors are a type of analytical device that can be classified according to the type of biological sensing element (enzymes, antibodies, aptamers, whole cells, etc.) that they employ or based on the transducer (e.g., electrochemical). The fundamental principle of electrochemical biosensors involves the specific interaction between an immobilized biological sensing element and a target analyte, resulting in alterations in signals (e.g., current, potential and impedance) that correlate with the analyte concentration. The transduction of a chemical or biological signal into an electrical signal can be achieved by various electroanalytical techniques (voltammetry, amperometry or electrochemical impedance spectroscopy, among others).

Electrochemical sensors and biosensors offer a number of advantages, including high sensitivity, low detection limits, and the ability to perform selective and reproducible measurements necessary to meet the rigorous demands of diverse applications. The performance of a biosensor depends on its intrinsic characteristics, such as physicochemical properties, composition, crystal phases, and the morphologies of the materials used for its fabrication. Novel materials and nanomaterials have been extensively used to enhance sensor performance due to their exciting characteristics (size-to-volume ratio, conductivity, surface and interfacial effects, quantum effects, etc.). Thus, determining the appropriate materials is key for developing and fabricating sensors with superior performance for next-generation diagnostics and analysis.

The combination of novel materials and electroanalytical techniques is very promising in further advancing electrochemical sensor and biosensor platforms and devices for various applications, including healthcare diagnostics, biological, biomedical, dairy and agri-food, water and environmental monitoring.

This Special Issue aims to collect the latest developments in advanced and novel materials for electrochemical sensing and biosensing applications to further accelerate innovations in these fields. Original research papers, reviews, and perspective articles are all welcome.

Dr. Baljit Singh
Guest Editor

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Keywords

  • electrochemical sensors and biosensors
  • sensor development
  • advanced materials
  • nanomaterials
  • nano-biosensors
  • flexible and wearable sensors
  • screen-printed sensors
  • electrode materials and fabrication
  • electrochemical analysis and electroanalytical techniques
  • healthcare diagnostics and biological analysis
  • dairy-agri-food, water and environmental monitoring

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Published Papers (1 paper)

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Review

26 pages, 4449 KB  
Review
Recent Progress in Electrocatalysts for Hydroquinone Electrochemical Sensing Application
by Mohammad Aslam, Khursheed Ahmad, Saood Ali, Khaled Hamdy and Danishuddin
Biosensors 2025, 15(8), 488; https://doi.org/10.3390/bios15080488 - 28 Jul 2025
Cited by 1 | Viewed by 982
Abstract
This review article compiled previous reports in the fabrication of hydroquinone (HQ) electrochemical sensors using differently modified electrodes. The electrode materials, which are also called electrocatalysts, play a crucial role in electrochemical detection of biomolecules and toxic substances. Metal oxides, MXenes, carbon-based materials [...] Read more.
This review article compiled previous reports in the fabrication of hydroquinone (HQ) electrochemical sensors using differently modified electrodes. The electrode materials, which are also called electrocatalysts, play a crucial role in electrochemical detection of biomolecules and toxic substances. Metal oxides, MXenes, carbon-based materials such as reduced graphene oxide (rGO), carbon nanotubes (CNTs), layered double hydroxides (LDH), metal sulfides, and hybrid composites were extensively utilized in the fabrication of HQ sensors. The electrochemical performance, including limit of detection, linearity, sensitivity, selectivity, stability, reproducibility, repeatability, and recovery for real-time sensing of the HQ sensors have been discussed. The limitations, challenges, and future directions are also discussed in the conclusion section. It is believed that the present review article may benefit researchers who are involved in the development of HQ sensors and catalyst preparation for electrochemical sensing of other toxic substances. Full article
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