Advances in Micro/Nano-Photonic Biosensors for Precision Diagnostics

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 1 June 2026

Special Issue Editor


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Guest Editor
Photonics Research Centre, Department of Electrical Engineering,The Hong Kong Polytechnic University, Kowloon, Hong Kong
Interests: Optical fiber-based devices; lasers and sensors; micro/nano-photonic structures; devices and biosensors
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Special Issue Information

Dear Colleagues,

Micro/nano-photonics has emerged as one of the most promising technologies for future biosensing due to its unique ability to harness lightwaves for the study of molecular interactions at the nanometer scale. It holds great promise in meeting the requirements of next-generation biosensors in terms of sensitivity, specificity, miniaturization, and parallelism. Consequently, it is poised to play a vital role in a variety of future biomedical applications, such as medical diagnostics, drug discovery, environmental monitoring, and beyond.

This Special Issue delves into cutting-edge developments in micro/nano-photonic biosensors, such as optical microcavity biosensors, nanoplasmonic biosensors, metasurface biosensors, and integrated photonic biosensors, highlighting their potential transformative impact on future precision diagnostics.

Key topics covered include, but are not limited to, the following:

  1. Innovative design and fabrication techniques: exploring the latest advancements in the design and fabrication of micro/nano-photonic biosensors, including optical microcavity, photonic crystal, and plasmonic sensors, which enhance light–matter interactions for improved sensor performance.
  2. Advances in single-molecule detection and analysis: emphasizing the ultrasensitive detection of single molecules using micro/nano-photonic biosensors, focusing on the investigation of the properties of individual molecules using photonic devices and sensing technologies.
  3. Integration with biological systems: discussing the integration of photonic biosensors with biological systems, paying attention to biocompatibility, functionalization with biomolecules, and real-time monitoring capabilities.
  4. Applications in healthcare: highlighting applications in healthcare, such as early disease detection, point-of-care diagnostics, and personalized medicine, where photonic sensors enable the rapid and accurate analysis of disease biomarkers.
  5. Emerging trends and future directions: considering emerging trends, such as the use of artificial intelligence (AI) for data analysis, miniaturization for portable devices, and the potential for integration with other technologies like microfluidics and lab-on-a-chip (LoC) devices.

This issue synthesizes contributions from leading researchers and industry experts, providing a comprehensive collection of the current state and future prospects of micro/nano-photonic biosensors. By showcasing innovative research and practical applications, it aims to inspire further advancements in this promising field.

Prof. Dr. A. Ping Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical microcavity biosensors
  • optical microring biosensors
  • photonic crystal biosensors
  • plasmonic biosensors
  • metasurface sensors
  • integrated photonic biosensors
  • optofluidic biochips
  • diagnosis
  • point-of-care
  • healthcare

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Published Papers

This special issue is now open for submission.
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