Aptamer-Based Biosensors for Point-of-Care Diagnostics
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".
Deadline for manuscript submissions: 15 November 2025 | Viewed by 590
Special Issue Editors
Interests: biosensors; electrochemistry; cancer; aptamers; gly-cans
Special Issues, Collections and Topics in MDPI journals
Interests: electrochemical and optical sensors; graphene; nanomaterials based electrodes; bioanalysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The dynamic field of molecular diagnostics and personalized medicine demands innovative approaches that deliver accurate and sensitive results in a fast, simple, and convenient manner at the point of need. The rapid advancement of point-of-care (POC) diagnostics has revolutionized healthcare by enabling timely and accurate disease detection outside traditional laboratory settings. Aptamer-based biosensors, leveraging the unique binding capabilities of aptamers—synthetic nucleic acid ligands—represent a promising approach to enhancing the sensitivity, specificity, and versatility of POC devices. These biosensors can detect a wide range of biomarkers (targets), including proteins, pathogens, and small molecules, making them invaluable tools in clinical diagnostics, infectious disease management, and personalized medicine.
This Special Issue aims to bring together innovative research and comprehensive reviews that highlight the development, optimization, and application of aptamer-based biosensors specifically for point-of-care diagnostics. We invite contributions from researchers across multidisciplinary fields to share their latest findings and insights. Topics include, but are not limited to, the following areas:
- Aptamer Selection and Engineering: Novel methods for the selection, design, and bioengineering of aptamers for enhanced binding specificity and stability.
- Biosensor Development: Innovative designs and fabrication techniques for aptamer-based biosensors tailored for POC applications, such as wearable formats, paper-based devices, and microfluidics.
- Detection Techniques: Exploration of signal transduction methods, including electrochemical, optical, and mass-sensitive detection approaches.
- Field Applications: Research demonstrating the use of aptamer-based biosensors in real-world POC settings, particularly in clinical diagnostics and infectious disease detection.
We look forward to your valuable contributions that will advance the field of aptamer-based biosensors and their impactful applications in point-of-care diagnostics.
Dr. Ana Díaz-Fernández
Prof. Dr. Cecilia Cristea
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aptamer
- biosensor
- point of care
- SELEX
- diagnostics
- precision medicine
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