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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanoparticles and Biomaterials: Pioneering Innovations in Biomedical Device Engineering

edited by Eleni Papachristou

submission deadline 30 Nov 2025 | Viewed by 59 | Submission Open

Keywords: nanoparticle NPs; biomaterials; drug delivery; mRNA delivery; antimicrobial activity; cancer; tissue regeneration; differentiation

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advanced Research in Congenital Heart Disease (CHD)

edited by Paul Philipp Heinisch

submission deadline 30 Nov 2025 | Viewed by 58 | Submission Open

Keywords: congenital heart disease (CHD); biomaterials; imaging modalities

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in the Pathogenesis and Treatment of Acute Myeloid Leukemia—2nd Edition

edited by

Alessandra Sperotto

submission deadline 30 Nov 2025 | Viewed by 58 | Submission Open

Keywords: acute myeloid leukemia; target therapies; molecular pathogenesis; biological therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Two Decades of Advances in Colorectal Cancer Prevention and Treatment: From Aspirin to Precision Oncology

edited by

Manish Tripathi

and

Puneet Vij

submission deadline 30 Nov 2025 | Viewed by 55 | Submission Open

Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways

(This special issue belongs to the Section Cancer Biology and Oncology)

Basic and Clinical Research of Psychiatric Diseases

edited by

Anita Kovács

submission deadline 30 Nov 2025 | Viewed by 52 | Submission Open

Keywords: psychiatric diseases; anxiety disorder; PTSD; schizophrenia; Alzheimer’ s disease; autism spectrum disorder; depression

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms of Cellular Senescence and Inflammation in Cardiovascular Disease

edited by Sivareddy Kotla

submission deadline 30 Nov 2025 | Viewed by 50 | Submission Open

Keywords: cellular senescence; inflammation; cardiovascular disease

(This special issue belongs to the Section Cell Biology and Pathology)

Human Dental Stem Cells: The Last 25 Years

edited by

Christian Morsczeck

submission deadline 30 Nov 2025 | Viewed by 50 | Submission Open

Keywords: dental stem cells; regenerative dentistry; differentiation; periodontitis

(This special issue belongs to the Section Cell Biology and Pathology)

Innovative Therapies for Neurodegenerative Diseases

edited by

Rosa María Giráldez-Pérez

, María Victoria Naval,

Javier Garcia-Pardo

and

Maria João Ramalho

submission deadline 30 Nov 2025 | Viewed by 49 | Submission Open

Keywords: nanotechnology-based therapies; cellular and regenerative therapies; stem cell therapy; gene therapy and RNA interference; protein aggregation inhibitors; neuroinflammation modulators; mitochondrial dysfunction-targeted drugs; preclinical and clinical trials

(This special issue belongs to the Section Gene and Cell Therapy)

Immunological Avalanches: Understanding Immune System Instability in Lupus, IgA Nephropathy, and Transplant Rejection

edited by

Davide Viggiano

, Giuseppe Gigliotti and Angelo Ferrantelli

submission deadline 30 Nov 2025 | Viewed by 47 | Submission Open

Keywords: immunological avalanche; lupus nephritis; IgA nephropathy; transplant rejection; complement dysregulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Pharmacology of Pain and Inflammation

edited by Fernanda Regina de Castro Almeida and Francisco De Assis Oliveira

submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open

Keywords: natural products; chronic pain; neuropathies; oncological pain; anti-inﬂammatory activity; pulmonary emphysema

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

From Cell Dysfunction to Prothrombotic Disorders: Molecular Pathways and Clinical Implications

edited by

Cristina Barale

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: prothrombotic disorder; cellular dysfunction; hemostatic balance; thrombosis; novel biomarkers; antithrombotic therapies

(This special issue belongs to the Section Cell Biology and Pathology)

Recent Advance in the Molecular Biology of Transplantation

edited by Anil S. Paramesh

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: donor-derived cell-free DNA; Torque Teno Virus monitoring; gene expression profiling; kidney/pancreas transplants

(This special issue belongs to the Section Immunology and Immunotherapy)

Gut Microbiota and Cancers of the GI Tract: Role in Regulation, Prevention and Therapy

edited by Luka Bočkor and

Jurica Žučko

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: gut microbiota; gastrointestinal cancers; gastrointestinal microbiota; anti-cancer therapies

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advancing Pharmacogenetics and Pharmacogenomics in Pre-Clinical Research: Unveiling New Avenues for Precision Medicine

edited by

Shengying Qin

and

Cong Huai

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: pharmacogenetics; pharmacogenomics; precision medicine; individualized medicine

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Activation and Regulation of NLRP3 Inflammasome

edited by

Wei Guo

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: NLRP3 inflammasome; innate immunity; inflammation; pyroptosis; caspase-1; IL-1β ; IL-18; DAMPs; PAMPs; inflammasome inhibitors; post-translational modifications; chronic inflammatory diseases; metabolic disorders; neurodegenerative diseases; therapeutic targeting

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Medically Assisted Reproduction

edited by

Theodoros Kalampokas

submission deadline 30 Nov 2025 | Viewed by 33 | Submission Open

Keywords: infertility; medically assisted reproduction; reproductive endocrinology; clinical embryology; genetics; artificial intelligence; epigenetics; precision medicine; evidence-based medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Human Immunodeficiency Virus (HIV): Past, Present and Future

edited by

Ana Borrajo

submission deadline 30 Nov 2025 | Viewed by 25 | Submission Open

Keywords: HIV latency; ART; HIV reservoirs; NeuroHIV; immune activation; HIV cure strategies; virus– host interactions; HIV comorbidities; HIV and ageing; translational HIV research

(This special issue belongs to the Section Cell Biology and Pathology)

Extracellular Matrix in Health and Disorders (2nd Edition)

edited by

Caterina Licini

submission deadline 15 Dec 2025 | Viewed by 26 | Submission Open

Keywords: ECM; connective tissue; healthy tissues; pathological tissues; imaging; drug targets; markers; dermis; bone; tendon

(This special issue belongs to the Section Molecular and Translational Medicine)

Personalized Treatment in Cancer Research, Second Edition

edited by

Silvia De Francia

and

Sarah Allegra

submission deadline 30 Dec 2025 | Viewed by 15 | Submission Open

Keywords: cancer; personalized medicine; personalized treatment; pharmacogenetics; pharmacokinetics; chemotherapy; adjuvant treatment; therapeutic drug monitoring

(This special issue belongs to the Section Cancer Biology and Oncology)

Cellular Senescence in Age-Related Diseases: Pathophysiology and Therapeutic Approaches

edited by

David J. Rademacher

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7661 | Submission Open

Keywords: cellular senescence; senescence-associated secretory phenotype; aging; senolytics; senomorphics; senoreverters; therapeutics

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Neurological Diseases: Pathogenesis, Diagnosis and Therapeutic Strategies

edited by

Foteini Christidi

and

Dimitrios Tsiptsios

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7584 | Submission Open

Keywords: neurological diseases; neurodegenerative diseases; stroke; multiple sclerosis; epilepsy; neuromuscular disorders; demyelinating diseases; traumatic brain injury; clinical neurophysiology; neuroimaging; genetics; neuropsychological tests; molecular and cellular mechanisms; biomarkers; diagnosis and therapeutics; prognosis; neurorehabilitation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research in Neuroprotection

edited by Evangelia Kesidou, Iliana Michailidou and

Christos Bakirtzis

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7205 | Submission Open

Keywords: neuroprotection; neurodegeneration; neuroinflammation; axonal loss; neuropharmacology; traumatic brain injury; blood– brain barrier

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Tumor Immune Microenvironment and Novel Strategies for Cancer Immunotherapy

edited by Sidra Islam

submission deadline 31 Dec 2025 | 5 articles | Viewed by 6630 | Submission Open

Keywords: tumor microenvironment cancer immunotherapy; immune markers; tumor infilterating immune cells; tumors

(This special issue belongs to the Section Immunology and Immunotherapy)

Challenges in the Diagnosis and Treatment of Parkinson’s Disease

edited by Iro Boura and Cleanthe Spanaki

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6360 | Submission Open

Keywords: Parkinson’ s disease; diagnosis; treatment; pathophysiology; biomarkers; prodromal; advanced therapies; subtypes; imaging; genetic

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of Factors in Embryo Implantation and Placental Development

edited by

Micol Massimiani

and Valentina Lacconi

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6337 | Submission Open

Keywords: placental development; implantation; embryo development; pregnancy disorders; endometrium; implantation failure; recurrent pregnancy loss; decidualization

(This special issue belongs to the Section Molecular and Translational Medicine)

Periodontal Disease: From Pathophysiology to Novel Therapeutic Approaches

edited by

Lu Li

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5925 | Submission Open

Keywords: periodontal disease; oral microbiome; dysbiosis; artificial intelligence (AI); personalized therapeutic interventions

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms, Implications, and Therapeutic Targets in Infectious Diseases

edited by Mihai Lazăr and Oana Săndulescu

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5523 | Submission Open

Keywords: infectious diseases; virus; antibiotics; pathophysiology; molecular mechanism; therapeutic management

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research on Heart Failure and Heart Transplantation

edited by

Nandan Kumar Mondal

submission deadline 31 Dec 2025 | 5 articles | Viewed by 4914 | Submission Open

Keywords: heart failure; heart transplantation; DBD (donation after brain death); DCD (donation after cardiac death); cardiac arrest; ischemic time and reperfusion injury; myocardial damage; preservation techniques; post-transplant outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

The Promise and Challenge of Induced Pluripotent Stem Cells (iPSCs): 2nd Edition

edited by

Xiufang Guo

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4438 | Submission Open

Keywords: iPSC; cell differentiation; disease model; disease-in-a-dish; body-on-a-chip; CRISPR/Cas9; gene edition; stem cell therapy; cell transplantation; translational

(This special issue belongs to the Section Molecular and Translational Medicine)

Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Serafino Fazio

and Valentina Mercurio

submission deadline 31 Dec 2025 | 5 articles | Viewed by 4091 | Submission Open

Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetic Regulation in Cancer Progression

edited by

Yonghwan Shin

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4023 | Submission Open

Keywords: cancer progression; epigenetic regulation; gene expression; dysregulation; therapeutic targets

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Neurotransmitters in Health and Diseases

edited by

Zsolt Bagosi

and Krisztina Csabafi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3609 | Submission Open

Keywords: neurotransmitters; GABA; dopamine; glutamate; acetylcholine; neurohormones; neuromodulators

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nano-Based Drug Delivery and Drug Discovery

edited by

Xiangli Shao

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2885 | Submission Open

Keywords: nanotechnology; drug discovery; drug delivery; nanocarriers; nanomaterials; drug targeting; drug release; drug therapeutic

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Antioxidant Materials with Additional Biological Properties

edited by

Nurettin Sahiner

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2633 | Submission Open

Keywords: natural antioxidants; flavonoids; and polyphenols; biocompatible and blood compatible; hydrogel; microgels; nanogel; and particles; polymeric particles; carbon quantum dots; and g-C3N4; stimuli-responsive materials; drug delivery systems; controlled release; and targeted delivery/therapies; antibacterial; antifungal; antiviral; anticancer; and biocidal; ROS-scavenging activity; proteins; enzyme; peptides; and amino acids; activate-able materials and photodynamic therapy

(This special issue belongs to the Section Biomedical Engineering and Materials)

Molecular Research in Breast Cancer

edited by

Anna De Blasio

and

Daniela Carlisi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1957 | Submission Open

Keywords: breast cancer; apoptosis; signaling pathways; drug resistance; metastasis; cancer stem cells; microRNA; biomarkers; drug target; tumor metabolism; tumor immunity

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Biomarker and Treatments for Diabetic Neuropathy

edited by Arun V. Krishnan and Tushar Issar

submission deadline 31 Dec 2025 | 4 articles | Viewed by 1808 | Submission Open

Keywords: diabetic peripheral neuropathy; type 1 diabetes; type 2 diabetes; glucagon-like peptide-1 receptor agonists; metabolic syndrome; in vivo corneal confocal microscopy; nerve ultrasonography; obesity; exercise

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Biological Therapies for Asthma: Targeting Type 1 and Type 2 Inflammation

edited by Mohammad Irshad Reza and Nilesh Sudhakar Ambhore

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1800 | Submission Open

Keywords: asthma endotypes; type 1 inflammation; type 2 inflammation; biological therapies for asthma; non-type 2 asthma; cytokine pathways in asthma; precision medicine in asthma; inflammatory biomarkers in asthma; Th1/Th2 immune responses

(This special issue belongs to the Section Molecular and Translational Medicine)

Traumatic CNS Injury: From Bench to Bedside (2nd Edition)

edited by

Andres M. Rubiano

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1541 | Submission Open

Keywords: neurotrauma; traumatic brain injury; translational science; bench to bedside; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Liver Disease: Etiology, Pathology, and Treatment

edited by Ivana Mikolašević

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1315 | Submission Open

Keywords: chronic liver disease; metabolic-associated fatty liver disease; liver fibrosis; liver injury; etiology; pathology; molecular and cellular mechanisms; biomarkers and therapeutic targets; immunotherapy; prevention and treatment

(This special issue belongs to the Section Cell Biology and Pathology)

From Molecules to Minds: Translational Breakthroughs in Preclinical Psychiatry

edited by

Masaru Tanaka

Simone Battaglia

and

Sandra Barbalho

submission deadline 31 Dec 2025 | Viewed by 1235 | Submission Open

Keywords: depression; anxiety; bipolar disorder; post-traumatic stress disorder; mental disorders; epigenomics; psychiatric disorders/genetics; circadian rhythm; sex characteristics; mitochondrial dysfunction; neurotoxins; intergenerational transmission; cannabinoid receptor modulators; adolescent neuroplasticity; synaptic pruning; psychoimmunology; preclinical studies; translational medical research; neuroplasticity; neuromodulation; phytochemicals; plant extracts; transcranial magnetic stimulation

(This special issue belongs to the Section Molecular and Translational Medicine)

Genetic and Molecular Mechanisms of Cardiometabolic Diseases and Cancers—2nd Edition

edited by Tao Wu and

Dafang Chen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1111 | Submission Open

Keywords: cardiometabolic disease; oncology; comorbidity; genetic pleiotropy; direct genetic effects; indirect genetic effects; parent-of-origin

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Recent Therapeutic Advances in Parkinson’s Disease

edited by

Chieh-Sen Chuang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1063 | Submission Open

Keywords: Parkinson's disease; disease-modifying therapy; continuous dopaminergic stimulation; non-dopaminergic drugs; deep brain stimulation; drug repurposing; immunotherapies; gene therapies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Hepatology

edited by Yuanwen Chen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 864 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); alcohol-associated liver disease (ALD); alcohol-associated hepatitis; viral hepatitis; liver cancer; autoimmune liver diseases; liver fibrosis; gut microbiota; neuroimmune; inflammatory mechanisms; oxidative stress; reversibly oxidized human non-mercaptalbumin-1; irreversibly oxidized human non-mercaptalbumin-2 (HNA2)

(This special issue belongs to the Section Molecular and Translational Medicine)

Current Trends in Regenerative Medicine

edited by

Leonidas Kandilogiannakis

and

Eirini Filidou

submission deadline 31 Dec 2025 | Viewed by 848 | Submission Open

Keywords: regenerative medicine; stem cells; organoids; tissue engineering; gene therapy; cell therapy; biomaterials; personalized medicine

(This special issue belongs to the Section Gene and Cell Therapy)

The Gut Microbiome in Early Life and Beyond: Implications for Health and Disease

edited by

Ye Peng

and

Shilan Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 830 | Submission Open

Keywords: gut microbiome; early-life development; DOHaD; microbial dysbiosis; chronic disease; probiotics; prebiotics; microbiome– host interactions; developmental programming; translational research

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advances in Reproductive Medicine and Health

edited by Athanasios Zikopoulos, Sofoklis Stavros and

Anastasios Potiris

submission deadline 31 Dec 2025 | Viewed by 820 | Submission Open

Keywords: reproductive medicine; assisted reproductive technology; fertility preservation; IVF; early pregnancy; miscarriages; proteomics; metabolomics; transcriptomics; infertility; bioethics; cryopreservation; personalized medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research on Psychiatric Disorders

edited by Wen Zhang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 774 | Submission Open

Keywords: psychiatric disorders; artificial intelligence; predictive modeling; personalized treatment strategies; animal experiments; risk factors; multimodal approaches

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Hematologic Malignancies: From Pathophysiologic Mechanisms to Therapeutic Strategies

edited by

Yun Chen

submission deadline 31 Dec 2025 | 1 articles | Viewed by 679 | Submission Open

Keywords: leukemia; hematological malignancies; tumor microenvironment; disease models; precision medicine; immunotherapy; targeted therapy; drug resistance; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathophysiology of Fatty Acid Metabolism

edited by

Nikolina Kolobarić

and

Ines Drenjančević

submission deadline 31 Dec 2025 | 1 articles | Viewed by 662 | Submission Open

Keywords: fatty acids; signalling molecules; gene expression; metabolic disorders

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Molecular Genomics of Oral Submucous Fibrosis Pathology

edited by Sanjit Mukherjee

submission deadline 31 Dec 2025 | Viewed by 623 | Submission Open

Keywords: oral submucous fibrosis; gene expression; biomarker; DNA methylation; epigenetic drugs; immune biomarkers; pathology; therapeutic interventions; epithelial mesenchymal transition; cancer stem cell marker

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 451-500 on page 10 of 15.

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