Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Liver Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 93 | Submission Open
Keywords: liver; obesity; alcohol; oxidative stress; nutrients; vitamins; metabolism; homeostasis
(This special issue belongs to the Section Cell Biology and Pathology)
Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications
edited by
submission deadline 31 Jan 2026 | Viewed by 92 | Submission Open
Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms  
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Cell Cycle in Normal Physiology and Disease
edited by
submission deadline 31 Jan 2026 | Viewed by 90 | Submission Open
Keywords: cell cycle; DNA replication; DNA damage; cyclins; cyclin-dependent kinases (CDKs); CDK inhibitors; cell proliferation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation
edited by
submission deadline 31 Jan 2026 | Viewed by 89 | Submission Open
Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
New Treatments for Colorectal Cancer
edited by
submission deadline 31 Jan 2026 | Viewed by 86 | Submission Open
Keywords: biomarkers; signaling pathway; chemotherapy; reactive oxygen species; angiogenesis
(This special issue belongs to the Section Cancer Biology and Oncology)
Biologic Drugs: The Evolution of Asthma Therapeutics submission deadline 31 Jan 2026 | Viewed by 84 | Submission Open
Keywords: severe asthma; IgE; IL-4; IL-5; IL-13; TSLP; monoclonal antibodies
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in 3D Printing for Drug Delivery Systems
edited by , Cristina Manuela Drăgoi and Alina Crenguța Nicolae
submission deadline 31 Jan 2026 | Viewed by 84 | Submission Open
Keywords: 3D printing; drug delivery systems; personalized medicine; pharmaceutical engineering; controlled release
(This special issue belongs to the Section Biomedical Engineering and Materials)
Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open
Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Pathways and Their Clinical Implications in Ischemic Heart Disease and Heart Failure: From Pathophysiology to Therapeutic Strategies
edited by and Efstratios Karagiannidis
submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open
Keywords: ischemic heart disease; heart failure; molecular mechanisms; biomarkers; targeted therapy; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Insights into HIV: Second Edition
edited by , Antonios Papadopoulos and
submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open
Keywords: HIV/AIDS; antiretroviral treatment; comorbidities; co-infection; neuroHIV
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Bioactive Lipids in Disease: Diagnosis, Prognosis, and Pathophysiology
edited by
submission deadline 31 Jan 2026 | Viewed by 81 | Submission Open
Keywords: bioactive lipids; eicosanoids; endocannabinoids; lysophospholipids; sphingolipids; oxysterols; bile acids; lipidomics; pathophysiology; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
The Latest Advancements in Tumor Drug Delivery Systems
edited by
submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: tumor targeting; gene delivery; biomemetic drug delivery; cancer-targeting nanorobot; specific cancer cell targeting; antitumor immunotherapy; cancer nanovaccine; tumor-suppressing nanoenzyme
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
New Advances in Neuroprotective Agent
edited by
submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: mitochondrial disfunction; antioxidant molecules; gene therapy; stem cell; nanomedicine; cellular reprogramming
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Genetically Determined Cardiovascular Disease
edited by
submission deadline 31 Jan 2026 | Viewed by 78 | Submission Open
Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Pharmacogenetics and Pharmacogenomics: Driving Forces in Modern Precision Medicine
edited by Miriam Saiz-Rodríguez and Dora Koller
submission deadline 31 Jan 2026 | Viewed by 77 | Submission Open
Keywords: pharmacogenetics; pharmacogenomics; precision medicine; polygenic risk scores; phenoconversion; drug response; genetic biomarkers; personalized therapy; underrepresented populations; clinical implementation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma
edited by Julia Federspiel, and
submission deadline 31 Jan 2026 | Viewed by 77 | Submission Open
Keywords: head and neck oncology 3D tumor models; cancer-associated fibroblasts; phototherapy; exosomes
(This special issue belongs to the Section Cancer Biology and Oncology)
Exploring Antiangiogenic Agents in Drug Discovery: Molecular Mechanisms and Therapeutic Implications submission deadline 31 Jan 2026 | Viewed by 76 | Submission Open
Keywords: angiogenesis; antiangiogenic agents; signaling pathway; preclinical model; drug discovery; computational tools
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Cancer Metastasis Modeling: From Mechanisms to Therapies
edited by
submission deadline 31 Jan 2026 | Viewed by 76 | Submission Open
Keywords: cancer metastasis; tumor microenvironment; extracellular matrix; metastasis models; drug resistance; in vivo imaging; molecular mechanisms; targeted therapy; computational modeling; and antibody-drug conjugates
(This special issue belongs to the Section Cancer Biology and Oncology)
Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition submission deadline 31 Jan 2026 | Viewed by 76 | Submission Open
Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering
(This special issue belongs to the Section Cell Biology and Pathology)
Microbiota and Immunity in Cancers
edited by Davide Frumento
submission deadline 31 Jan 2026 | Viewed by 64 | Submission Open
Keywords: immunology; cancer; microbiota; immunotherapy; probiotics; oncology
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Allergies and Autoimmunity
edited by
submission deadline 31 Jan 2026 | Viewed by 60 | Submission Open
Keywords: asthma; arthritis; diabetes; inflammatory bowel disease; dermatomyositis; Sjö gren's syndrome; systemic lupus erythematosus; psoriasis; multiple sclerosis
(This special issue belongs to the Section Cell Biology and Pathology)
Dopamine in Health and Disease (3rd Edition)
edited by
submission deadline 31 Jan 2026 | Viewed by 59 | Submission Open
Keywords: dopamine; disease models; mitochondria; Parkinson’ s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Nanoparticles in Medicine: The Potential of “Empty” Nanoparticles and Future Challenges
edited by Cuthbert O Simpkins and
submission deadline 31 Jan 2026 | Viewed by 53 | Submission Open
Keywords: nanoparticles; empty nanoparticles; nanoparticle technology
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Advances in Cancer Cell Metabolism and Tumor Microenvironment
edited by
submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open
Keywords: metabolism; cancer; immune cells; tumor microenvironment; cancer-associated organ failure; cancer therapeutics
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Emerging Therapeutic Approaches to Head and Neck Cancer
edited by and Daria Maria Filippini
submission deadline 31 Jan 2026 | Viewed by 48 | Submission Open
Keywords: head and neck cancer; HPV-related head and neck cancer; EBV-related nasopharyngeal cancer; prognostic biomarkers; predictive biomarkers; novel combinations; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
The Prefrontal Cortex in Cognition and Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 47 | Submission Open
Keywords: executive function; working memory; behavioral inhibition; attention; anxiety; social behavior; ADHD (attention-deficit hyperactivity disorder); schizophrenia; MDD (major depressive disorder); AD (Alzheimer's disease); PD (Parkinson’ s disease)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Innovations in Understanding and Treating Pancreatic Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 46 | Submission Open
Keywords: pancreatic cancer; pancreatitis; tumor microenvironment; epithelial– mesenchymal transition (EMT); metastasis; liver metastatic niche; immunotherapy; biomarkers; targeted therapies; inflammation and fibrosis
(This special issue belongs to the Section Cell Biology and Pathology)
Biochemical and Molecular Perspectives on Engineered Nanoparticles for Cancer Therapy submission deadline 10 Feb 2026 | Viewed by 161 | Submission Open
Keywords: cancer; oxidative stress; engineered nanoparticles (ENPs); drug delivery; biochemical processes; ferroptosis; apoptosis; cell death; molecular interactions; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Innovations in Bone and Craniofacial Tissue Engineering: From Biomaterials and Mechanobiology to Clinical Applications
edited by Zhekai Hu
submission deadline 15 Feb 2026 | Viewed by 114 | Submission Open
Keywords: bone tissue engineering; craniofacial regeneration; biomaterials and scaffolds; stem cells and exosomes; mechanobiology and orthodontic forces; osteoimmunology; oxidative stress modulation; gene/drug delivery; translational research; periodontal and alveolar bone regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Emerging Trends in Malignant Mesothelioma
edited by Yuan Xu
submission deadline 20 Feb 2026 | Viewed by 243 | Submission Open
Keywords: mesothelioma; asbestos; novel therapeutic strategies; treatment resistance; multi-omics analysis
(This special issue belongs to the Section Cancer Biology and Oncology)
Autophagic Signatures in Health and Disease: Molecular Insights and Clinical Applications submission deadline 20 Feb 2026 | Viewed by 82 | Submission Open
Keywords: autophagy; pathology; physiology; therapy; methods
(This special issue belongs to the Section Cell Biology and Pathology)
Obstructive Sleep Apnea: Mechanisms, Comorbidities, and Optimization of Emerging and Established Therapies submission deadline 25 Feb 2026 | 1 articles | Viewed by 1858 | Submission Open
Keywords: obstructive sleep apnea; sleep-disordered breathing; pathophysiology; cardiometabolic comorbidities; precision medicine; CPAP; sleep diagnostics; biomarkers; neurocognitive impairment; new therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 27 Feb 2026 | Viewed by 177 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathology, Complications and Prognosis of Type 1 Diabetes
edited by Maurizio Delvecchio
submission deadline 27 Feb 2026 | Viewed by 45 | Submission Open
Keywords: type 1 diabetes mellitus; autoimmune β -cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research of Gut Microbiota in Health and Diseases—2nd Edition submission deadline 28 Feb 2026 | 8 articles | Viewed by 17180 | Submission Open
Keywords: microbiota; gut; dysbiosis; gut microbiome; pathological conditions; metabolic disorders; autoimmune disease; inflammatory disorders; degenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Cellular and Molecular Biology of Neurodegenerative Disorders
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 13541 | Submission Open
Keywords: neurodegeneration; omics; biomarkers; systems biology; disease-modifying therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Glioblastoma: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 28 Feb 2026 | 5 articles | Viewed by 13418 | Submission Open
Keywords: drug delivery methods (TTFields; nanoparticles); immunotherapy; oncolytic virotherapy; cell metabolism (glycolysis; OXPHOS; fatty acid oxidation); epigenetic; biomarkers; gene therapy (CRISPR/Cas9)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cellular and Pathogenesis Mechanisms in Oral Cancer
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 12935 | Submission Open
Keywords: oral carcinogenesis; oral cancer model; OSCC; oral cytology; biomarkers; targeted therapies; precision medicine; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Musculoskeletal Injuries: Clinical, Radiological, and Biochemical Evaluation in Orthopedics submission deadline 28 Feb 2026 | 6 articles | Viewed by 10806 | Submission Open
Keywords: orthopedic surgery; sports injuries; bone cancer; diabetic foot; clinical evaluation; radiological evaluation; biomarkers; prognostic markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 10387 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Feature Reviews in Cell Death
edited by and Madalina Nistor
submission deadline 28 Feb 2026 | 4 articles | Viewed by 9003 | Submission Open
Keywords: cell death pathways; apoptosis; necrosis; biomarkers; therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Progress in Cardiovascular Pharmacology submission deadline 28 Feb 2026 | 3 articles | Viewed by 7643 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Biomarker Discovery for Cardiovascular Disease
edited by and
submission deadline 28 Feb 2026 | 6 articles | Viewed by 6419 | Submission Open
Keywords: cardiovascular disease; genomics; transcriptomics; proteomics; metabolomics; multiomics; gene sequencing; liquid chromatography/gas chromatography tandem mass spectrometry; diagnostic biomarkers; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Mesenchymal Stem Cells submission deadline 28 Feb 2026 | 2 articles | Viewed by 6210 | Submission Open
Keywords: mesenchymal stem cells; tissue repair and regeneration; immunomodulatory functions
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention
edited by and
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5935 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Nanotechnology-Based Therapeutic Strategies
edited by Ambra Del Grosso and Mariacristina Gagliardi
submission deadline 28 Feb 2026 | 3 articles | Viewed by 4629 | Submission Open
Keywords: nanotechnology-based therapies; targeted drug delivery; nanoparticles; nanostructures; cancer treatment; cardiovascular diseases; neurodegenerative diseases; infectious diseases; lysosomal storage disorders; regenerative medicine; tissue engineering; gene therapy; biochemical diagnostics; omics approaches; biological barriers
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Animal Models for the Study of Human Diseases
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 4427 | Submission Open
Keywords: animal models; zebrafish; mice; rats
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Breast Diseases and Histopathology
edited by Michał Budzik
submission deadline 28 Feb 2026 | 3 articles | Viewed by 3726 | Submission Open
Keywords: breast cancer; breast diseases; histopathology; biomarkers; screening; diagnosis; early detection; tumor microenvironment; pathophysiology; molecular biology
(This special issue belongs to the Section Cell Biology and Pathology)
The Role of Ion Channels and Transporters in Human Health and Diseases (2nd Edition)
edited by Teresa Soda
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3238 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; piezo channels; NALCN channels; inositol-1; 4; 5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Kidney Diseases in Critical Ill Patients
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2892 | Submission Open
Keywords: acute kidney disease; critical care; beside diagnostics; point of care ultrasounds; dialysis
(This special issue belongs to the Section Molecular and Translational Medicine)
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