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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Molecular Mechanisms and Treatment of Neurological Diseases

edited by

Zhouqing Chen

and Yanbo Yang

submission deadline 30 Sep 2025 | Viewed by 41 | Submission Open

Keywords: neurological disease; molecular mechanisms; neuroinflammation; metabolism; biomarkers; neuroprotection; gene therapy; omics; drug discovery; personalized medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diagnostic and Therapeutic Approaches to Pancreatic Cancer—Second Edition

edited by

Sanchita Rauth

submission deadline 30 Sep 2025 | Viewed by 36 | Submission Open

Keywords: pancreatic cancer; systemic therapy; immunotherapy; tumor microenvironment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Cytogenetics in Health and Diseases

edited by

Rong Xiang

submission deadline 30 Oct 2025 | Viewed by 35 | Submission Open

Keywords: genetic mutations; high-throughput sequencing; genomics; multiomics; rare diseases

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathological Biomarkers in Precision Medicine

edited by

Ovidiu Constantin Baltatu

, Mirela A. Dobre and Tudor Groza

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9987 | Submission Open

Keywords: pathological biomarkers; precision medicine; artificial intelligence; medical imaging; omics data analysis; personalized medicine; biomarker discovery; digital pathology

(This special issue belongs to the Section Cell Biology and Pathology)

Breast Cancer: New Diagnostic and Therapeutic Approaches

edited by

Erika Bandini

Tania Rossi

and Sara Bravaccini

submission deadline 31 Oct 2025 | 7 articles | Viewed by 9086 | Submission Open

Keywords: breast cancer; breast oncology; circulating tumor cells

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Fetal Medicine and Neonatology

edited by

Robert Brawura-Biskupski-Samaha

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5093 | Submission Open

Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Issues in Retinal Degeneration

edited by

Ponarulselvam Sekar

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4682 | Submission Open

Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection

(This special issue belongs to the Section Cell Biology and Pathology)

Mechanisms and Pharmacological Targets for Pain

edited by Renan F. do Espírito-Santo

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4653 | Submission Open

Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain

(This special issue belongs to the Section Molecular and Translational Medicine)

Genetic Research on Neuropsychiatric Disorders and Complex Human Diseases

edited by Wen Zhang

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4290 | Submission Open

Keywords: neuropsychiatric disorders; complex human diseases; genetic research; omics data analysis; high-throughput sequencing; machine learning; disease mechanism

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms of Steroid Hormone Action—2nd Edition

edited by

Omar Cauli

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4058 | Submission Open

Keywords: oestrogen; androgens; thyroid; adrenal gland; menopause; cancer

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advanced Research in Atrial Fibrillation

edited by

Wern Yew Ding

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3319 | Submission Open

Keywords: atrial fibrillation; arrhythmia; electrophysiology; cardiovascular; mechanism; laboratory; experimental

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies

edited by

Dalia El-Gamal

and

Audrey Smith

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3199 | Submission Open

Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Research in Obesity, 2nd Edition

edited by Zaida Abad-Jiménez and

Teresa Vezza

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2574 | Submission Open

Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis, Diagnosis, and Treatment of Respiratory Diseases

edited by

Te-Chun Shen

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2490 | Submission Open

Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia; tuberculosis; respiratory failure; ARDS; COVID-19; obstructive sleep apnea

(This special issue belongs to the Section Cell Biology and Pathology)

Gynecological Diseases in Cellular and Molecular Perspectives

edited by

Iwona Wertel

and

Anna Pawłowska-Łachut

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2318 | Submission Open

Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases

edited by

Jinghua Wang

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2301 | Submission Open

Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetic Regulation and Its Impact for Medicine (2nd Edition)

edited by

Marie Černá

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2004 | Submission Open

Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches in In Vitro Skin Models: From Design to Application

edited by

Tina Maver

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2000 | Submission Open

Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling

(This special issue belongs to the Section Biomedical Engineering and Materials)

Head and Neck Tumors, 4th Edition

edited by

Silvia Di Agostino

and

Jan B. Vermorken

submission deadline 31 Oct 2025 | 4 articles | Viewed by 1801 | Submission Open

Keywords: head and neck tumors; predictive markers; liquid biopsy; therapy; precision medicine; biomaterials

(This special issue belongs to the Section Cancer Biology and Oncology)

Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)

edited by

Juan Gambini

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1779 | Submission Open

Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging

(This special issue belongs to the Section Immunology and Immunotherapy)

Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition

edited by

Giulia Lunghi

Elena Chiricozzi

and

Maria Fazzari

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1655 | Submission Open

Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research in Hypertrophic Cardiomyopathy

edited by Said Alsidawi,

Juan Farina

and

Celestino Sardu

submission deadline 31 Oct 2025 | 5 articles | Viewed by 1648 | Submission Open

Keywords: hypertrophic cardiomyopathy; myosin inhibitors; genetic therapy; risk stratification

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Developments in Mycobacterial Research

edited by

Vishwanath Venketaraman

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1591 | Submission Open

Keywords: Mycobacterium tuberculosis; mycobacterial; host immune responses

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1467 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice

edited by Tanveer Singh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1384 | Submission Open

Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

MicroRNA and Its Role in Human Health, 2nd Edition

edited by

Shih-Yao Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1369 | Submission Open

Keywords: microRNA; disease models; disease associations; molecular mechanism; molecular diagnosis; molecular therapy

(This special issue belongs to the Section Cell Biology and Pathology)

Maternal-Fetal and Neonatal Medicine

edited by

Dimitrios Papageorgiou

submission deadline 31 Oct 2025 | Viewed by 1279 | Submission Open

Keywords: maternal– fetal health; neonatal health; prenatal care; prenatal diagnosis; fetal growth; diabetes mellitus; hypertension; pre-eclampsia; congenital infections; gene therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Secondary Immunodeficiency in Oncohematological Diseases

edited by

Giuseppe Murdaca

and

Sebastiano Gangemi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1197 | Submission Open

Keywords: secondary immunodeficiencies and opportunistic infections; secondary immunodeficiencies and B-lymphocytes; secondary immunodeficiencies and hematological diseases; secondary immunodeficiencies and cancers; secondary immunodeficiencies and novel cancer treatments; secondary immunodeficiencies and oxidative stress

(This special issue belongs to the Section Immunology and Immunotherapy)

Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition

edited by

Mária Szekeres

György L. Nádasy

and

László Dézsi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1165 | Submission Open

Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Tumor Immunology

edited by

Maria-Ioanna Christodoulou

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1154 | Submission Open

Keywords: tumor immunity; immunotherapy; engineered immune cells; antibodies; immunomodulators; cytokines; survival; immune-checkpoint inhibitors; tumor immune microenvironment

(This special issue belongs to the Section Immunology and Immunotherapy)

New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo

edited by

Alfredo Caturano

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1141 | Submission Open

Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Unraveling New Horizon in Vascular Diseases: From Pathophysiology to Novel Therapeutic

edited by Miguel A. Ortega and

Raul Diaz-Pedrero

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1133 | Submission Open

Keywords: vascular diseases; artery; venous disease; venous hypertension; heart; lymph; diabetes; surgery; immune system; translational medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases

edited by Jixin Zhong

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1063 | Submission Open

Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1028 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Sex Hormones and Cardiovascular Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Renáta Szabó

and

Denise Börzsei

submission deadline 31 Oct 2025 | 1 articles | Viewed by 996 | Submission Open

Keywords: endogenous sex hormones; aging; sexual dimorphism; hormone replacement therapy; CVDs; hypertension; myocardial infarction; atherosclerosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Microbial Metabolites and Their Impact on Gut Homeostasis

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 963 | Submission Open

Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Protein Misfolding and Functional Impairment in Neurodegenerative Diseases

edited by

Marios Krokidis

Themis Exarchos

and

Panayiotis Vlamos

submission deadline 31 Oct 2025 | 1 articles | Viewed by 894 | Submission Open

Keywords: protein misfolding; chaperones; energy landscape; neurodegenerative diseases; amyloidogenesis; intrinsically disordered proteins; structure prediction algorithms; bioinformatics; molecular dynamic simulations

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Updates on Kawasaki Disease

edited by Eisuke Suganuma

submission deadline 31 Oct 2025 | 1 articles | Viewed by 753 | Submission Open

Keywords: coronary artery aneurysm; cluster; individualized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Novel Therapeutics in Musculoskeletal Conditions, 3rd Edition

edited by

Juan Antonio Valera-Calero

and

Gustavo Plaza-Manzano

submission deadline 31 Oct 2025 | 2 articles | Viewed by 605 | Submission Open

Keywords: neck pain; low back pain; myofascial pain syndromes; chronic pain; musculoskeletal disorders; disability; pain treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploitation and Development of “Synthetic Lethality” Strategy for Cancer Therapy

edited by Guo Chen

submission deadline 31 Oct 2025 | Viewed by 604 | Submission Open

Keywords: anti-cancer therpies; PARP inhibitors; synthetic lethality

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations

edited by

Rui Caetano Oliveira

, Rui Miguel Martins and

José Guilherme Tralhão

submission deadline 31 Oct 2025 | 1 articles | Viewed by 545 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Cell Signaling and Molecular Regulation in Neurodegenerative Disease

edited by Shao-Ming Wang

submission deadline 31 Oct 2025 | Viewed by 421 | Submission Open

Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of Endothelial Cells in Cardiovascular Disease—2nd Edition

edited by

Lorenzo Falsetti

and

Vincenzo Zaccone

submission deadline 31 Oct 2025 | Viewed by 343 | Submission Open

Keywords: endothelial cells; endothelial dysfunction; cardiovascular disease; endothelial progenitor cells; atherosclerosis; thrombosis; vessel inflammation; regenerative medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Strategies for Anticancer in p53 Mutated Cancers

edited by

Bi-He Cai

and

Ching-Feng Lien

submission deadline 31 Oct 2025 | 1 articles | Viewed by 325 | Submission Open

Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Inflammatory Skin Diseases

edited by

Angelo Ruggiero

Luca Potestio

and

Matteo Megna

submission deadline 31 Oct 2025 | Viewed by 316 | Submission Open

Keywords: inflammatory skin diseases; pathophysiology; therapeutic strategies; novel treatments; skin disorders

(This special issue belongs to the Section Immunology and Immunotherapy)

Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches

edited by Alan P. Lombard

submission deadline 31 Oct 2025 | Viewed by 314 | Submission Open

Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Heparan Sulfate Biology: Protein Interactions and Therapeutic Implications

edited by Miaomiao Li

submission deadline 31 Oct 2025 | Viewed by 305 | Submission Open

Keywords: heparan sulfate; heparin; heparanase; heparan sulfate-binding protein; heparan sulfate oligosaccharides; antibody; natural sulfated carbohydrates

(This special issue belongs to the Section Cell Biology and Pathology)

Progress in Neonatal Pulmonary Biology

edited by

Fumihiko Namba

submission deadline 31 Oct 2025 | Viewed by 292 | Submission Open

Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut–Brain Axis and Diabetes

edited by Nikolett Bódi

submission deadline 31 Oct 2025 | Viewed by 288 | Submission Open

Keywords: diabetes; gut– brain axis; enteric nervous system; central nervous system; microbiota; enteroendocrine cells; inflammation; immune responses

(This special issue belongs to the Section Endocrinology and Metabolism Research)

The Role of Oxidative Stress in Metabolic Syndrome

edited by

Bojlul Bahar

submission deadline 31 Oct 2025 | Viewed by 275 | Submission Open

Keywords: free radical; oxidative stress; ROS; NRF2; Keap1; metabolic syndrome; chronic inflammation; cardiovascular disease; obesity; diabetes

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 451-500 on page 10 of 14.

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