New Advances in the Pathology, Diagnosis and Treatment of Thyroid Tumors
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 103
Special Issue Editor
Special Issue Information
Dear Colleagues,
Thyroid cancer (TC) is a complex aspect of immuno-oncology and endocrinology, being associated with various biases and paradigms. One such bias is gender (e.g., to Riedel’s thyroiditis), with women showing an advantage compared to men at the level of 4:1. However, when considering the frequency of visits to endocrinologists, one can see how difficult it is to perform an equivalent study, contrary to simple, retrospective data collection.
Similarly, in the clinic, the low incidence of Medullary TC is associated with the performance of fewer calcitonin tests than TSH, with thyroxin being used in initial screenings. Likewise, lymphomas are rarely recognized as a primary focus in the thyroid gland, because abundant lymphoid cells (including small lymphocytes from germinal centers) are observed in Hashimoto thyroiditis. Non-Hodgkin lymphoma is diagnosed via neck node biopsy, but this may have metastasized from the primary thyroid.
Surgery is considered the optimum treatment; however, as in surgery, total thyroidectomy cannot be compared with subtotal, radioiodine or immunotherapy, especially when an observational strategy is employed (as in pharmacology—a placebo effect).
Finally, with a plateau in the incidence of thyroid cancer and an overestimation of local of TC (alongside the underreporting of metastatic of TC), the role of thyroid supplements remains unclear.
Special Issue welcomes the submission of articles that focus on the mechanisms implicated in the oncogenesis of TC, its diagnosis and potential therapeutic regimens.
Dr. Przemyslaw Zdziarski
Guest Editor
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Keywords
- goitre
- thyroid cancer
- screening
- bias
- paraneoplastic syndrome
- immunosurveillance
- thyroiditis
- thyroidectomy
- immunotherapy
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