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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Eicosanoids and Fatty Acids in Health, Diseases and Therapeutics

edited by Mihai Nechifor

submission deadline 28 Feb 2026 | Viewed by 80 | Submission Open

Keywords: eicosanoids; prostaglandins; leukotrienes; prostacyclin; lipoxins; resolvins; protectins; maresins; arachidonic acid (AA); eicosapentaenoic acid (EPA); docosahexaenoic acid (DHA); cell functions; immunity; cardiovascular; neuropsychiatric; metabolic; digestive; reproductive; hematologic; inflammatory and oncologic pathology; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Human Stem Cells in Disease Modelling and Treatment (2nd Edition)

edited by Sofia M. Calado and

Álvaro Plaza Reyes

submission deadline 28 Feb 2026 | Viewed by 78 | Submission Open

Keywords: induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); disease models; cell therapies; cell therapy medicinal products (CTMPs); regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Insights into Breast Cancer Management: From Tumorigenesis to Personalized Treatments—2nd Edition

edited by

Rita De Sanctis

and

Paola Tiberio

submission deadline 28 Feb 2026 | Viewed by 78 | Submission Open

Keywords: breast cancer; diagnosis; prognosis; treatment response prediction; biomarkers; risk factors; new therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Liver Cancer: Molecular and Translational Insights of Carcinogenesis and Treatments

edited by

Joon Hyuk Choi

submission deadline 28 Feb 2026 | Viewed by 76 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; intrahepatic cholangiocarcinoma; carcinogenesis; premalignant lesions; diagnosis; pathology; treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Research Progress on Antimicrobial Resistance (AMR)

edited by

Tomohiro Oishi

submission deadline 28 Feb 2026 | Viewed by 76 | Submission Open

Keywords: antimicrobial resistance; mechanism; therapy; experiment; bacteria; antibiotics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies (2nd Edition)

edited by

Hee-Eun Kim

submission deadline 28 Feb 2026 | Viewed by 72 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Pyroptosis and Cellular Stress: Emerging Mechanisms and Therapeutic Targets

edited by Gang Du

submission deadline 28 Feb 2026 | Viewed by 70 | Submission Open

Keywords: pyroptosis; cellular stress; ROS; programmed cell death; gasdermin; cytokines; inflammation; infection; cellular metabolism; immunometabolism

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Liver Fibrosis: From Mechanisms to Therapeutics

edited by

Kun Zhang

submission deadline 28 Feb 2026 | Viewed by 70 | Submission Open

Keywords: liver fibrosis; therapeutic target; biomarker; hepatocyte; macrophage; LSEC; HSC; immune cells; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

Thyroid Disease: From Mechanism to Therapeutic Approaches (2nd Edition)

edited by

Beata Wojtczak

submission deadline 28 Feb 2026 | Viewed by 69 | Submission Open

Keywords: pathogenesis and molecular mechanism of thyroid diseases; genetic disorders of the thyroid; biomarkers for thyroid dysfunctions; diagnostic challenges; new thyroid’ s therapies; immunotherapy; nuclear medicine; minimally invasive treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Kidney Disease: From Pathophysiology to Treatment

edited by

Paola Pontrelli

and

Francesca Conserva

submission deadline 28 Feb 2026 | Viewed by 68 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; precision medicine; molecular mechanisms; biomarkers; therapeutic response

Molecular Diagnostics in Diabetes: From Biomarkers to Clinical Applications

edited by

Robert Stawski

and Konrad Walczak

submission deadline 28 Feb 2026 | Viewed by 67 | Submission Open

Keywords: diabetes; molecular diagnostics; cell-free DNA (cfDNA); microRNAs; circulating biomarkers; diabetes complications; personalized therapy

(This special issue belongs to the Section Cell Biology and Pathology)

State of the Art in Mitochondrial Research

edited by

Jan Ježek

submission deadline 28 Feb 2026 | Viewed by 64 | Submission Open

Keywords: mitochondrial metabolism; bioenergetics; mitochondrial signaling; mitochondrial dynamics; reactive oxygen species; apoptosis; hypoxia; mitochondrial genetics; mitochondrial diseases; aging

(This special issue belongs to the Section Cell Biology and Pathology)

Intestinal Homeostasis and Disease Dysbiosis

edited by

Nikolas Dovrolis

submission deadline 28 Feb 2026 | Viewed by 64 | Submission Open

Keywords: gut microbiota; intestinal homeostasis; dysbiosis; microbiota– drug interactions; host– microbe interactions; microbiome therapeutics; precision medicine

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Immunotherapy and Immune-Related Adverse Events in Cancer

edited by

Ivana Mikolašević

submission deadline 28 Feb 2026 | Viewed by 61 | Submission Open

Keywords: immunotherapy; cancer; PD-1 inhibitors; immune-related adverse effects; management

(This special issue belongs to the Section Immunology and Immunotherapy)

Encephalitis and Viral Infection: Mechanisms and Therapies—2nd Edition

edited by Bradley S. Hollidge and

Samantha S. Soldan

submission deadline 28 Feb 2026 | Viewed by 58 | Submission Open

Keywords: neurovirology; encephalitis; gene therapy; viral vectors; virology; immunology; neuroscience; gene editing; neuroinflammation; arboviruses; innate immunity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diagnosis and Treatment of Periodontal Disease

edited by

Khaing Myat Thu

submission deadline 28 Feb 2026 | Viewed by 57 | Submission Open

Keywords: periodontitis; gingivitis; periimplantitis; artificial intelligence; X-ray; periodontal treatment; plaque control; oral hygiene

(This special issue belongs to the Section Molecular and Translational Medicine)

The Tumor Microenvironment and Heterogeneity: Challenges and Opportunities in Multiple Myeloma Immunotherapy

edited by

Enze Liu

submission deadline 28 Feb 2026 | Viewed by 56 | Submission Open

Keywords: multiple myeloma; immunotherapies; tumor microenvironment; novel targets; surfaceome; expression heterogeneity

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis, Diagnosis and Treatment of Endocrine Cancers

edited by

Rajeev Parameswaran

submission deadline 28 Feb 2026 | Viewed by 55 | Submission Open

Keywords: thyroid; parathyroid; adrenal; paraganglioma; genomes; transcriptomes; signalling pathways; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Generative Artificial Intelligence in Biomedical Sciences: Transforming Research, Diagnosis, and Therapy

edited by Iman Tavassoly

submission deadline 28 Feb 2026 | Viewed by 54 | Submission Open

Keywords: artificial intelligence; biomedical data; generative models; machine learning; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Contribution of Neural Stemness and Its Regulatory Networks to Tumorigenesis

edited by

Ying Cao

submission deadline 28 Feb 2026 | Viewed by 53 | Submission Open

Keywords: neural stemness; tumorigenicity; pluripotency; phenotypic heterogeneity; cancer cell; cancer cell-intrinsic neural factors; differentiation therapy via targeting neural stemness; tumorigenesis; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

Anti-Cancer Agents: Synthesis and Evaluation of Pharmacological Activity

edited by Sureshbabu Popuri

submission deadline 28 Feb 2026 | Viewed by 51 | Submission Open

Keywords: anticancer agents; synthesis; pharmacological evaluation; medicinal chemistry; small molecules; metal complexes; structure– activity relationship (SAR); cytotoxic activity; apoptosis; drug discovery; chemotherapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Thyroid Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment

edited by Sonam Kumari

submission deadline 28 Feb 2026 | Viewed by 51 | Submission Open

Keywords: radioactive iodine (RAI) treatment; tyrosine kinase inhibitors (TKIs); biomarkers; radiolabeled peptides; diagnostic markers; molecular targets; metastatic progressive thyroid cancer; overcoming resistance; personalized therapies; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Mechanisms of Cardiovascular Diseases (CVDs)

edited by

Xiaoquan Rao

submission deadline 28 Feb 2026 | Viewed by 47 | Submission Open

Keywords: cardiovascular diseases (CVDs); molecular mechanisms; metabolic dysregulation; immunity; immunometabolism

(This special issue belongs to the Section Molecular and Translational Medicine)

Channelopathies: Drug Interactions and Clinical Advances

edited by Cesar Celis Ceballos

submission deadline 28 Feb 2026 | Viewed by 46 | Submission Open

Keywords: electrophysiology; ion channels; channelopathies; drugs; patch-clamp

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Metabolic Dysregulation in Chronic Kidney Disease: Emerging Mechanisms and Targeted Therapies

edited by

Leszek Niepolski

submission deadline 28 Feb 2026 | Viewed by 43 | Submission Open

Keywords: chronic kidney disease; metabolic dysregulation; biomarkers; gut-kidney axis; targeted therapy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Molecular Mechanisms of Coronary Disease

edited by Quanyi Zhao and João P. Monteiro

submission deadline 28 Feb 2026 | Viewed by 42 | Submission Open

Keywords: atherosclerosis; coronary artery disease; cell fate transition; transcription; epigenetics; genetics; cytokine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advance Research in Cancer Immunotherapy

edited by

Sheila Spada

submission deadline 28 Feb 2026 | Viewed by 42 | Submission Open

Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology

(This special issue belongs to the Section Cancer Biology and Oncology)

New Insights in Immunological Pathways

edited by

Wan-Chung Hu

submission deadline 28 Feb 2026 | Viewed by 40 | Submission Open

Keywords: immune response; immune signal pathway; cytokine storm

(This special issue belongs to the Section Immunology and Immunotherapy)

Liquid Biopsy in Tumor

edited by Heidi Fettke

submission deadline 28 Feb 2026 | Viewed by 39 | Submission Open

Keywords: cfDNA; ctDNA; liquid biopsy; solid tumors; fragmentomics; MRD; cancer genomics; non-invasive biomarkers; treatment resistance; precision oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Novel Biomarkers and Precision Medicine in Gynecologic Malignancies

edited by Zheng Feng

submission deadline 28 Feb 2026 | Viewed by 37 | Submission Open

Keywords: clinical trials; genomic landscape; targeted therapy; liquid biopsy; tumor screening; biomarker research; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

3D Cell Culture Systems for Biomedical Research, 2nd Edition

edited by

Agnieszka Rusak

and

Benita Wiatrak

submission deadline 28 Feb 2026 | Viewed by 33 | Submission Open

Keywords: 3D; scaffolds; spheroids; biomaterials; tumour model; bioengineering; tissue regeneration; regenerative medicine; targeted therapies; tissue mimics; angiogenesis; cancerogenesis; drug development; 3D printing; material functionalisation

(This special issue belongs to the Section Biomedical Engineering and Materials)

Regenerative Medicine for Bone and Cartilage

edited by Deryk Jones

submission deadline 28 Feb 2026 | Viewed by 28 | Submission Open

Keywords: articular cartilage; bone marrow lesion; osteochondral allograft and autograft; chondrocyte; trabeculae; magnetic resonance image; regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Precision Approaches in the Diagnosis and Management of Inflammatory Bowel Disease

edited by

Jiayu Ye

submission deadline 28 Feb 2026 | Viewed by 25 | Submission Open

Keywords: inflammatory bowel disease; ulcerative colitis; Crohn’ s disease; precision medicine; microbiome-based therapy; noninvasive diagnostics; stratified therapeutic response; immunometabolism; system immunology; therapeutic repurposing

(This special issue belongs to the Section Cell Biology and Pathology)

Laser Applications in Medicine: Current Status and Emerging Challenges

edited by Irit Juwiler

submission deadline 16 Mar 2026 | Viewed by 216 | Submission Open

Keywords: lasers; medicine; surgery; dermatology; ophthalmology; dentistry; otolaryngology; gastroenterology; urology; gynecology; cardiology; neurosurgery; orthopedics; tissue types; biological interactions; technological advancements; clinical applications; health outcomes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Recent Advances in Chronic Rhinosinusitis and Asthma: 2nd Edition

edited by

Giuseppe Guida

and Cristiano Caruso

submission deadline 30 Mar 2026 | 1 articles | Viewed by 923 | Submission Open

Keywords: asthma; chronic rhinosinusitis; nasal polyps; severe asthma; type-2 inflammation; phenotypes; endotypes; biologics; epithelial disfunction; remodeling

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomarkers in Pain: 2nd Edition

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 30 Mar 2026 | Viewed by 157 | Submission Open

Keywords: analgesia; biomarker; CSF; cytokine; inflammation; neuropathy; neurotransmitter; pain; QoL; sensitization; sensory

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research—2nd Edition

edited by

Cristiana Bustea

submission deadline 30 Mar 2026 | Viewed by 69 | Submission Open

Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research

(This special issue belongs to the Section Molecular and Translational Medicine)

Metabolic Dysfunction-Associated Steatotic Disease

edited by Junzhao Ye

submission deadline 30 Mar 2026 | Viewed by 65 | Submission Open

Keywords: metabolic dysfunction-associated fatty liver disease; metabolic dysfunction-associated steatotic disease; novel classification using proteomic and metabolomic profiles; new kinds of lifestyle modification interventions; especially for nutrition interventions; radiologic advances in steatosis; inflammation; and fibrosis assessments; artificial intelligence applications; therapeutic innovations; microbiota

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Genetic and Epigenetic Research on Kidney Diseases

edited by Hailong Hu

submission deadline 30 Mar 2026 | Viewed by 53 | Submission Open

Keywords: kidney disease; genetics; epigenetics; DNA methylation; non-coding RNAs; precision medicine; therapeutic target; nephrology

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advanced Research in Cell and Tissue Engineering

edited by

Yoshitaka Miyamoto

submission deadline 30 Mar 2026 | Viewed by 46 | Submission Open

Keywords: cell and tissue engineering; regenerative medicine; stem cells; organoid; biomaterials; extracellular matrix (ECM); micro electro mechanical systems (MEMSs); microphysiological systems (MPSs); medical device; decellularization (decellularized tissue)

(This special issue belongs to the Section Biomedical Engineering and Materials)

Cholinergic System Neurodegeneration: Novel Pharmacotherapy

edited by

Javier del Pino

and Paula Moyano

submission deadline 31 Mar 2026 | 1 articles | Viewed by 13171 | Submission Open

Keywords: cholinergic system; neurodegeneration; acetylcholine; cholinergic neurons; cholinergic pathologies; therapeutic approaches

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Crohn’s Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Dingpei Long

and Junsik Sung

submission deadline 31 Mar 2026 | 11 articles | Viewed by 13099 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Long COVID: Mechanisms, Biomarkers, and Treatment

edited by

Frédérique Ponchel

submission deadline 31 Mar 2026 | 3 articles | Viewed by 12589 | Submission Open

Keywords: long-COVID; clinical observations; disease mechanism; biomarkers; treatment strategies; opinions

(This special issue belongs to the Section Cell Biology and Pathology)

Clinical Electrophysiology for Precision Diagnosis for Cardiology and Central Nervous System Diseases

edited by

Fátima Regina Mena Barreto Silva

and

Diana Marcela Aragon Novoa

submission deadline 31 Mar 2026 | 3 articles | Viewed by 10756 | Submission Open

Keywords: brain; cardiology; precision medicine.

(This special issue belongs to the Section Molecular and Translational Medicine)

Saving Lives from Myocardial Infarction: Prevention vs. Therapy

edited by Dong Wang

submission deadline 31 Mar 2026 | 3 articles | Viewed by 8246 | Submission Open

Keywords: myocardial infarction; molecular markers; AI-powered early detection; wearable devices; ischemia– reperfusion injury; artificial intelligence; ventricular remodeling; fibrosis control; molecular imaging; genomics; transcriptomics; proteomics; metabolomics; MI prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Multidisciplinary Management of Rare Head and Neck Tumors: The Importance of Knowing and Dealing with Them

edited by

Francesco Perri

submission deadline 31 Mar 2026 | 3 articles | Viewed by 7480 | Submission Open

Keywords: rare head and neck cancers; translational research; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated

edited by

Consolato M. Sergi

and

Paola Di Carlo

submission deadline 31 Mar 2026 | 4 articles | Viewed by 6917 | Submission Open

Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Lung Cancer: From Bench to Bedside

edited by

Seung Hyeun Lee

submission deadline 31 Mar 2026 | 5 articles | Viewed by 5577 | Submission Open

Keywords: lung cancer; immunotherapy; targeted therapy; translational oncology; biomarkers; EGFR; ALK; ROS1

(This special issue belongs to the Section Cancer Biology and Oncology)

New Insights in Gastric, Colorectal, and Pancreatic Cancer

edited by

John K. Triantafillidis

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5559 | Submission Open

Keywords: gastric cancer ; colorectal cancer ; pancreatic cancer; immunotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Connective Tissue Disorders: Pathogenetic, Diagnostic and Therapeutic Perspectives

edited by

Katarzyna Winsz-Szczotka

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5167 | Submission Open

Keywords: connective tissue disorders; pathophysiological mechanisms; inflammation; autoimmunity; extracellular matrix; fibrosis; biomarkers; treatment; therapeutic targets

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 551-600 on page 12 of 16.

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