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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Reviews in Cancer Genetics and Epigenetics

edited by

Zheng-Yuan Su

submission deadline 30 Jun 2026 | Viewed by 331 | Submission Open

Keywords: cancer genetics; epigenetics; DNA methylation; histone modifications; non-coding RNAs; tumor heterogeneity; drug resistance; biomarkers; precision oncology; personalized therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances of Microbiome in Human Cancers

edited by

Weg M. Ongkeko

submission deadline 30 Jun 2026 | Viewed by 294 | Submission Open

Keywords: human microbiome; gut microbiota; tumor-resident microbes; translational research; biomarkers; computational biology

(This special issue belongs to the Section Cancer Biology and Oncology)

Cancer-Associated Thrombosis: From Biomarkers to Diagnostic and Therapeutic Strategies to Optimize Treatment

edited by

Roberta Pancani

, Gualtiero Palareti and Emilia Antonucci

submission deadline 30 Jun 2026 | Viewed by 281 | Submission Open

Keywords: cancer-associated thrombosis; venous thrombosis; biomarkers; pulmonary embolism; precision medicine; diagnostic optimization

(This special issue belongs to the Section Cancer Biology and Oncology)

Exercise-Induced Physiological Responses: From Oxidative Stress to DNA Alterations

edited by

Robert Stawski

submission deadline 30 Jun 2026 | Viewed by 235 | Submission Open

Keywords: exercise-induced oxidative stress; reactive oxygen species (ROS); molecular adaptations to exercise; epigenetic modifications in exercise; DNA damage and repair; cell-free DNA; extracellular DNA; inflammation and exercise; DNA alterations

(This special issue belongs to the Section Cell Biology and Pathology)

Antipsychotics: 70 Years—2nd Edition

edited by

Giovanni Lentini

and

Serge Mignani

submission deadline 30 Jun 2026 | Viewed by 216 | Submission Open

Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; complementary medicine; psychosis; schizophrenia; bipolar disorder; Alzheimer’ s disease

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Novel Biomaterials and Tissue Engineering Approaches in Periodontal Regeneration

edited by

Federico Mussano

submission deadline 30 Jun 2026 | Viewed by 214 | Submission Open

Keywords: periodontium; tissue engineering; regenerative medicine; biomaterials; bioprinting; mesenchymal stem/stromal cells; senescence; aging; advanced therapeutics

(This special issue belongs to the Section Biomedical Engineering and Materials)

The Preparation of an Exosome/Liposomal Nano-Drug Delivery System and Its Application in the Treatment of Inflammatory Bowel Disease

edited by

Dingpei Long

and

Jialing Bao

submission deadline 30 Jun 2026 | Viewed by 213 | Submission Open

Keywords: exosomes; liposomes; nano-drug delivery systems; inflammatory bowel disease (IBD); targeted therapy; mucosal drug delivery; drug encapsulation; immunomodulation; nanomedicine; extracellular vesicles; personalized medicine

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Morpho-Molecular and Genetic Basis of Cardiomyopathies

edited by

Andrea Frustaci

submission deadline 30 Jun 2026 | Viewed by 213 | Submission Open

Keywords: dilated cardiomyopathy; hypertrophic cardiomyopathy; restrictive cardiomyopathy; inflammatory cardiomyopathy; myocardial storage diseases; genetic investigations

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Airway Inflammation and Lung Dysfunction

edited by Aruni Jha

submission deadline 30 Jun 2026 | Viewed by 195 | Submission Open

Keywords: airway inflammation; lung dysfunction; acute respiratory distress syndrome (ARDS); chronic obstructive pulmonary disease (COPD); asthma; airway remodeling; therapeutic strategies; inflammation mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Inflammation in Neurogenerative Diseases: Mechanisms and Therapeutic Frontiers

edited by

Shao-Bin Wang

submission deadline 30 Jun 2026 | 1 articles | Viewed by 179 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; biomarkers mitochondria dysfunction; microglia; immune response; therapeutic development; gene therapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers—2nd Edition

edited by

Sadhna Aggarwal

submission deadline 30 Jun 2026 | Viewed by 179 | Submission Open

Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therap; tumor growth; tumor invasion; angiogenesis; tumor metastasis; immune response modulation

(This special issue belongs to the Section Cancer Biology and Oncology)

Nanoparticles and Biomaterials: Pioneering Innovations in Biomedical Device Engineering

edited by Eleni Papachristou

submission deadline 30 Jun 2026 | Viewed by 157 | Submission Open

Keywords: nanoparticle NPs; biomaterials; drug delivery; mRNA delivery; antimicrobial activity; cancer; tissue regeneration; differentiation

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advancements and Innovations in Chemotherapy

edited by

Yu-Jung Lin

submission deadline 30 Jun 2026 | Viewed by 154 | Submission Open

Keywords: chemotherapy; drug resistance; immunotherapy; combination therapy; drug delivery systems; novel agents; personalized medicine; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Kidney Diseases Research

edited by

Yi-Che Lee

submission deadline 30 Jun 2026 | Viewed by 140 | Submission Open

Keywords: kidney diseases; biomarkers; artificial intelligence; diagnostics; dialysis; immunomodulation; regenerative medicine

AI/Machine Learning-Driven Multi-Omics Research in Oncology

edited by Wenjun Mao,

Renjun Gu

and Yize Mao

submission deadline 30 Jun 2026 | Viewed by 137 | Submission Open

Keywords: artificial intelligence; machine learning; multi-omics; oncology; precision medicine; biomarker discovery; cancer genomics; deep learning

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Parkinson’s Disease Research

edited by Valentino Racki

submission deadline 30 Jun 2026 | Viewed by 130 | Submission Open

Keywords: Parkinson’ s disease; movement disorders; neurodegeneration; biomarkers; deep brain stimulation; infusion therapies; gut– brain axis; neuroinflammation; personalized medicine; atypical parkinsonism

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical, and Translational Neuropsychiatry—3rd Edition

edited by

Masaru Tanaka

and Simone Battaglia

submission deadline 30 Jun 2026 | Viewed by 123 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; psychiatric disorders; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Human Dental Stem Cells: The Last 25 Years

edited by

Christian Morsczeck

submission deadline 30 Jun 2026 | Viewed by 115 | Submission Open

Keywords: dental stem cells; regenerative dentistry; differentiation; periodontitis

(This special issue belongs to the Section Cell Biology and Pathology)

The Aging Metabolism: Diabetes, Obesity, and Lifespan Insights

edited by

Rafael Ramírez-Carracedo

and

Rafael Moreno-Gómez-Toledano

submission deadline 30 Jun 2026 | Viewed by 109 | Submission Open

Keywords: metabolic diseases; aging; obesity; diabetes; cell signaling

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Human Immunodeficiency Virus (HIV): Past, Present and Future

edited by

Ana Borrajo

submission deadline 30 Jun 2026 | Viewed by 108 | Submission Open

Keywords: HIV latency; ART; HIV reservoirs; NeuroHIV; immune activation; HIV cure strategies; virus– host interactions; HIV comorbidities; HIV and ageing; translational HIV research

(This special issue belongs to the Section Cell Biology and Pathology)

Genitourinary Cancers: From Molecular Pathogenesis to Precision Diagnosis and Therapy

edited by

Qi-Dong Xia

and Jian-Xuan Sun

submission deadline 30 Jun 2026 | Viewed by 103 | Submission Open

Keywords: genitourinary tumors; molecular pathogenesis; tumor microenvironment; biomarkers; liquid biopsy; immunotherapy; targeted therapy; therapy resistance; precision diagnosis

(This special issue belongs to the Section Cancer Biology and Oncology)

Venous and Lymphatic Diseases: Updates on Phlebo-Lymphology and Cross-Talk

edited by

Sergiu-Ciprian Matei

and

Sergio Gianesini

submission deadline 30 Jun 2026 | Viewed by 95 | Submission Open

Keywords: chronic venous disease; chronic venous insufficiency; venous leg ulcers; venous reflux; vein wall; glycocalyx; lymphoedema; lipoedema

(This special issue belongs to the Section Molecular and Translational Medicine)

Artificial Intelligence Applications in Neuroscience and Brain Diseases

edited by

Marios Krokidis

submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open

Keywords: neuroscience; brain diseases; neurology and neurodegeneration; artificial intelligence; machine learning; bioinformatics; neuroimaging; neurotechnology; multimodal data integration; brain– computer interfaces; personalized medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Targeted Nanomedicine: From Design to Application

edited by

Ming Ma

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: targeted nanomedicine; nanocarriers; nanosystems; drug delivery

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Update on Cancer Therapy

edited by

Jian Ruan

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: cancer; cancer immunotherapy; targeted therapy; ccancer vaccines; therapeutic agents; drug resistance mechanisms

(This special issue belongs to the Section Cancer Biology and Oncology)

Thyroid Disorders: Comprehensive Insight from Functional Abnormalities, Structural Lesions to Autoimmunity

edited by

Darko Katalinić

submission deadline 30 Jun 2026 | Viewed by 87 | Submission Open

Keywords: thyroid gland pathology; autoimmunity; immunopathogenesis; diagnostic biomarkers; therapeutic strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

Novel Insights into Depression Research: Neurobiology, Models, Biomarkers and Therapies

edited by

Adela Magdalena Ciobanu

submission deadline 30 Jun 2026 | Viewed by 86 | Submission Open

Keywords: depression; neurobiology; biomarkers; experimental models; antidepressant therapies; personalized medicine; treatment resistance; pharmacology; psychiatric disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Cardiac Arrhythmias: Technological Frontiers, Therapeutic Approaches and Future Directions

edited by

Panteleimon Pantelidis

Polychronis E. Dilaveris

, Raffaele De Lucia and

Evangelos Oikonomou

submission deadline 30 Jun 2026 | Viewed by 85 | Submission Open

Keywords: cardiac arrhythmias; electrophysiology; implantable devices; artificial intelligence; translational medicine; arrhythmogenesis; e-cardiology; biomarkers; telemonitoring

(This special issue belongs to the Section Molecular and Translational Medicine)

Multiple Sclerosis: From Early Diagnosis to Personalized Treatment Strategies

edited by Alberto Calvi

submission deadline 30 Jun 2026 | Viewed by 83 | Submission Open

Keywords: multiple sclerosis; susceptibility; deformation-based techniques; PRL; GFAP; machine learning

(This special issue belongs to the Section Immunology and Immunotherapy)

Next-Generation Approaches in Clinical Antiviral Therapy: From Bench to Bedside

edited by

Pouya Hassandarvish

submission deadline 30 Jun 2026 | Viewed by 82 | Submission Open

Keywords: clinical antiviral therapy; antiviral potential; novel drug discovery platforms; host-targeted antivirals; drug repurposing; combination therapies; resistance mechanisms; clinical trial; viral infections; viral diseases

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Immunology in Recurrent Pregnancy Loss, Preeclampsia and Infertility

edited by

Jenny Valentina Garmendia

submission deadline 30 Jun 2026 | Viewed by 81 | Submission Open

Keywords: immunology of pregnancy; recurrent pregnancy loss; infertility; preeclampsia; autoimmunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Emerging Molecular and Translational Insights into Obstructive Sleep Apnea and Its Cardiovascular Comorbidities

edited by Hui-Ting Wang and

Yunglung Chen

submission deadline 30 Jun 2026 | Viewed by 81 | Submission Open

Keywords: obstructive sleep apnea (OSA); atrial fibrillation (AF); molecular mechanisms; epigenetics; biomarkers; oxidative stress; inflammation; endothelial dysfunction; translational research; precision medicine; artificial intelligence; cardiovascular comorbidities

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Hereditary Diseases: Insights from Genetic Perspectives

edited by

Maud de Dieuleveult

submission deadline 30 Jun 2026 | Viewed by 77 | Submission Open

Keywords: genetic mutations; inheritance patterns; genomic medicine; monogenic disorders; genetic counseling

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Precision Oncology in Solid Tumors: Emerging Biomarkers and Therapeutic Targets

edited by Giuseppe Nicolò Fanelli

submission deadline 30 Jun 2026 | Viewed by 74 | Submission Open

Keywords: precision oncology; predictive biomarkers; target therapy; molecular pathology; liquid biopsy; tumor microenvironment; immunotherapy; multi-omics integration; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Treatment of Amyotrophic Lateral Sclerosis (ALS)

edited by

Dongsheng Fan

submission deadline 30 Jun 2026 | Viewed by 73 | Submission Open

Keywords: amyotrophic lateral sclerosis (ALS); multi-target therapy; drug repurposing; translational research; biomarkers; induced pluripotent stem cells (iPSCs); clinical trial design; AI-based prediction models; precise treatment

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pathogenesis, Diagnosis and Treatment of Infectious Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: infection; infectious diseases; vaccination; antibiotics; antibiotic resistance; novel therapies; novel diagnosis; inflammaging; immunosenescence

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in the Diagnosis and Treatment of Urothelial Cancers

edited by Aleksander Ślusarczyk and

Łukasz Zapała

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: bladder cancer; urethral cancer; upper tract urothelial carcinoma

(This special issue belongs to the Section Cancer Biology and Oncology)

Integrative Insights into Biology, Diagnosis and Treatment of Pulmonary Diseases

edited by

Te-Chun Shen

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: pulmonary medicine; critical care; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; lung cancer; respiratory infection; obstructive sleep apnea (OSA); respiratory failure; acute respiratory distress syndrome (ARDS)

(This special issue belongs to the Section Molecular and Translational Medicine)

Metabolic Reprogramming and Immune Modulation in the Tumor Microenvironment: From Mechanisms to Immunotherapy Enhancement

edited by

Reza Bayat Mokhtari

submission deadline 30 Jun 2026 | Viewed by 68 | Submission Open

Keywords: cancer metabolism; tumor microenvironment; immune modulation; immunotherapy resistance; metabolic reprogramming; immunosuppression; combination therapy; biomarkers; metabolic plasticity; anti-tumor immunity

(This special issue belongs to the Section Cancer Biology and Oncology)

Lipid Nanoparticles for Cancer Immunotherapy

edited by Qiyan Wang

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: mRNA; LNP; cancer vaccine; immune therapy; target delivery

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathogenesis, Diagnostics, and Therapeutics for Rheumatic Diseases (2nd Edition)

edited by Jixin Zhong

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: rheumatic diseases; pathogenesis; autoimmunity; biomarkers; precision medicine; therapeutics; disease management; immunology; clinical diagnostics; treatment strategies

(This special issue belongs to the Section Molecular and Translational Medicine)

Multiple Sclerosis: From Early Diagnosis to Personalized Therapeutic Approaches

edited by

Marta Ponzano

submission deadline 30 Jun 2026 | Viewed by 67 | Submission Open

Keywords: multiple sclerosis; diagnosis; revised criteria; neuroimaging; therapy; disability; individual well-being

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of DNA Methylation in Human Health and Diseases

edited by

Ting-Hai Xu

submission deadline 30 Jun 2026 | Viewed by 65 | Submission Open

Keywords: DNA methylation; epigenetics; translational research; biomarker; gene regulation; epigenetic therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Nano-Mediated Drug Delivery

edited by

Zhengxing Li

submission deadline 30 Jun 2026 | Viewed by 64 | Submission Open

Keywords: engineered nano-carriers; nanomedicine; micro/nanorobotics; targeted drug delivery; intelligent controllable systems; biohybrid systems; RNA therapeutics; translational nanotechnology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advanced Research in Melanoma Metastasis

edited by

Viktória Koroknai

submission deadline 30 Jun 2026 | Viewed by 62 | Submission Open

Keywords: melanoma; metastasis; tumor– host interactions; pre-metastatic niche; tumor microenvironment; organ-specific metastasis; molecular mechanisms; therapeutic targets

(This special issue belongs to the Section Cancer Biology and Oncology)

Atopic Dermatitis in the Precision Medicine Era: Immunological Mechanisms, Biomarkers, and Therapeutic Innovations

edited by

Mihail Virgil Boldeanu

submission deadline 30 Jun 2026 | Viewed by 62 | Submission Open

Keywords: atopic dermatitis; immunopathology; skin barrier biology; neuroimmune signaling; microbiome interactions; therapeutic targets; biomarkers; personalized treatment approaches

(This special issue belongs to the Section Molecular and Translational Medicine)

Thrombophilia and Haemophilia: Pathophysiology and Therapeutic Interventions

edited by Petr Dulíček

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: hemophilia; therapy; thrombophilia; F XI inhibitors

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanomaterials for Drug Delivery: Current Status and Future Prospects

edited by

Bing Guo

and Madappa C. Maridevaru

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: nanomaterials for drug delivery; metal– organic frameworks (MOFs); porous nanomaterials; polymeric nanocarriers; inorganic nanoparticles; hybrid drug delivery systems; controlled drug release; targeted delivery; stimuli-responsive nanocarriers; biocompatible nanoplatforms; theranostics; precision nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Genomics and Epitranscriptomics Regulation in Cancer

edited by Ilias Georgakopoulos-Soares and

Candace S. Y. Chan

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: cancer genomics; epitranscriptomics; RNA modifications; non-coding RNAs; gene expression regulation; RNA splicing

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research in Hematological Malignancies

edited by

Te-Fu Weng

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: hematological malignancies; leukemia; lymphoma; myeloma

(This special issue belongs to the Section Cancer Biology and Oncology)

Displaying special issue 551-600 on page 12 of 15.

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