Stem Cell Therapy: Traps and Tricks
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Biomedical Engineering and Materials".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 98
Special Issue Editors
Interests: challenges in animal model research; translation; unbiased reporting of animal model characteristics and results; ethical justification
Special Issues, Collections and Topics in MDPI journals
2. Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia
Interests: kidney transplantation; regenerative medicine and substitutive therapies of acute and end-stage kidney failure; transplanted stem cells; nephrology
Special Issue Information
Dear Colleagues,
Over the years, stem cell therapy has garnered significant interest as a treatment for various diseases. The therapeutic potential of mesenchymal stem cells (MSCs) has been explored in numerous animal models and veterinary patients. While preclinical research has reported beneficial treatment effects, these findings have led to the initiation of several clinical trials, which have yielded inconsistent results. Additionally, recent experiences have highlighted numerous reports of adverse events and side-effects associated with MSC therapy.
This experience underscores that there are many challenges and pitfalls in regenerative medicine that are often overlooked in the literature, hindering progress in the field and leading to unnecessary financial costs and safety concerns. A comprehensive understanding of these limitations, challenges, and pitfalls is essential for fostering advancements in stem cell therapy.
Therefore, this Special Issue aims to compile articles and reviews addressing the current obstacles, limitations, and side-effects that impede progress in the field, as well as potential strategies and solutions to overcome these issues.
Dr. Martina Perše
Dr. Željka Večerić-Haler
Guest Editors
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Keywords
- mesenchymal stem cells
- MSC therapy
- preclinical research
- regenerative medicine
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