Stem Cell Biology and Tissue Engineering for Cardiology
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 8
Special Issue Editor
Interests: atrial fibrillation; heart failure; ESC guidelines implementation; post-mortem cardiovascular pathology; digital health and wearables in cardiology; beta-blocker therapy; sex-specific cardiovascular risk; cardiac imaging and ECG diagnostics
Special Issue Information
Dear Colleagues,
Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, posing a formidable challenge in modern medicine despite decades of advances in pharmacological therapies and surgical interventions. While traditional treatments focus on managing symptoms and preventing progression, they offer limited potential in regenerating lost or damaged myocardial tissue. In recent years, the emergence of stem cell biology and tissue engineering has opened up a transformative frontier in the pursuit of cardiac regeneration and functional repair.
This Special Issue, “Stem Cell Biology and Tissue Engineering for Cardiology”, will spotlight the latest innovations, experimental breakthroughs, and translational insights shaping the future of cardiovascular regenerative medicine. Stem cell-based therapies—including pluripotent, mesenchymal, and cardiac progenitor cell systems—offer promising strategies to replenish cardiomyocytes, modulate inflammation, and stimulate endogenous repair mechanisms. Concurrently, advances in biomaterials, bioprinting, scaffold design, and organoid modeling have propelled cardiac tissue engineering into a new era of precision and personalization.
We invite contributions that explore these evolving paradigms from both basic science and clinical perspectives. Topics of interest include, but are not limited to, the following:
Mechanistic insights into stem cell differentiation and cardiogenesis;
- Innovations in cardiac scaffold fabrication and biomaterials;
- Organoid and microfluidic models for cardiac development and disease;
- Immunomodulatory properties of stem cell-derived products;
- Preclinical and clinical studies evaluating the efficacy and safety of regenerative therapies;
- Translational challenges in stem cell-based cardiology.
Our goal is to curate a diverse collection of original research articles, reviews, and perspectives that reflect the interdisciplinary nature of this rapidly advancing field. We believe that fostering dialog between cell biologists, bioengineers, clinicians, and translational scientists will be essential in moving regenerative cardiology from bench to bedside.
We look forward to receiving your valuable contributions to this Special Issue of Biomedicines and working together to advance the collective mission of restoring cardiovascular health through innovation in stem cell biology and tissue engineering.
Dr. Otilia Țica
Guest Editor
Manuscript Submission Information
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Keywords
- cardiac regeneration
- stem cell therapy
- cardiac tissue engineering
- mesenchymal stem cells (MSCs)
- induced pluripotent stem cells (iPSCs)
- cardiomyocyte differentiation
- myocardial repair
- 3D bioprinting
- biomaterials in cardiology
- cardiac scaffolds
- heart organoids
- translational regenerative medicine
- cell-based therapy
- cardiovascular bioengineering
- immunomodulation in cardiac repair
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