Zebrafish Models: From Basic Research to Translational Medicine

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 12

Special Issue Editors


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Guest Editor
Georgia Cancer Center, Medical College of Georgia at Augusta University, Augusta, GA 30912, USA
Interests: zebrafish model organism in health prevention, preservation, and treatment; zebrafish transparent transgenic cellular phenotype development and applications; experimental therapeutics; high throughput drug discovery; identification of hit and lead drugs; repurposing of FDA-approved drugs in disease treatment and prevention; genomics; tumor microenvironment; pharmacogenomics; drug-induced toxicity; glioblastoma; microglia pathophysiology; cancer drug-induced cardiotoxicity

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Guest Editor
Division of Cardiology, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA
Interests: interventional cardiology; preventative cardiology; cardiovascular thromboinflammatory pathways; coronary microvascular dysfunction; zebrafish cardiovascular disease models; drug-induced cardiotoxicity; vascular biology; pulmonary embolism and venous thromboembolism; mechanical thrombectomy; endovascular interventions

Special Issue Information

Dear Colleagues,

Zebrafish have emerged as a powerful model organism in biomedical research, bridging the gap between basic science and clinical applications. With its high genetic homology to humans, rapid development, transparency, and suitability for high-throughput screening, the zebrafish model offers unique advantages for studying developmental biology, disease mechanisms, drug discovery, and toxicology. In recent decades, zebrafish have made significant contributions to breakthroughs in cancer research, neurobiology, cardiovascular disease, and regenerative medicine.

This Special Issue aims to collate innovative research that demonstrates the utility of zebrafish models in advancing our understanding of human diseases and therapeutic development. The scope of this Special Issue aligns with the journal’s focus on experimental and translational biology, covering molecular mechanisms, disease modeling, drug screening, and biomedical applications. For this Special Issue, original research articles and reviews are welcome to be submitted.

We look forward to receiving your contributions and collaborating with you to advance the field of zebrafish biomedical research.

Dr. Surendra Rajpurohit
Prof. Dr. Vishal Arora
Guest Editors

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Keywords

  • zebrafish
  • animal models
  • in vivo whole model organism imaging
  • epigenetics
  • physiological and functional discoveries
  • genetic engineered transgenic cellular and mutant phenotype
  • developmental biology
  • drug discovery
  • high-throughput drug screening
  • pharmacogenomics
  • translational research
  • toxicology
  • genomics
  • cardiology
  • cardio-oncology
  • cardiovascular diseases
  • cardio-oncology
  • cancer models
  • melanoma
  • tumor microenvironment
  • dermatology
  • ophthalmology
  • neuroscience
  • aging
  • neurodegenerative disease
  • diabetes
  • kidney disease
  • hematology

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Published Papers

This special issue is now open for submission.
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