New Trends in Regional Anesthesia and Pain Management
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 946
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue delves into the latest trends in regional anesthesia and pain management, emphasizing innovations within the biomedical field. Regional analgesic techniques have emerged as a major aspect of the Enhanced Recovery After Surgery (ERAS) protocol. Notably, the integration of AI into the planning and execution of the regional technique promises to further enhance outcomes by optimizing nerve block placement and individualizing treatment plans. Furthermore, percutaneous microlead implantation for continuous peripheral nerve stimulation has been developed in order to preferentially affect the sensory fibers (SPRint PNS system) with an adjustable period of action. In addition to its civilian applications, such technical advancements have gained significant attention in military medicine. To save the lives of patients with ongoing traumatic bleeding requiring amputation, regional anesthesia exhibits unique value in the context of modern conflict and warfare. In war zones where traditional general anesthesia equipment may be unavailable, ultrasound- or nerve stimulator-guided peripheral nerve blocks offer a practical strategy for performing surgeries without anesthesia machines and the shock induced by neuraxial block during bleeding. Furthermore, a curriculum is now required to train anesthesiologists in rescuing the lives of military trauma patients. For transporting military trauma patients, catheterization for continuous infusion is more adequate, either via neuraxial or peripheral perineural routes. While TEA procedures can be technically challenging, innovations such as EpiFaith or CompuFlo have emerged to enhance safety and efficacy.
To effectively manage chronic pain, a multimodal approach that incorporates various treatment strategies is often necessary. In addition to the advancement of regenerative and nutritional pain medicine, minimally invasive interventional techniques, such as transarterial microembolization or joint denervation, have emerged as promising techniques for addressing pain conditions in which traditional pain management strategies have proven limited in their effectiveness. These innovative techniques offer a targeted and potentially transformative approach to managing complex pain conditions.
This Special Issue welcomes the submission of original research papers, communication, opinion and comprehensive reviews that address these emerging trends, including the latest clinical applications and future directions.
Dr. Jui-An Lin
Guest Editor
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Keywords
- regional anesthesia
- ultrasound-guided/stimulator-guided nerve blocks
- novel techniques for motor-sparing neural intervention
- continuous catheter infusions
- opioid-sparing techniques
- perioperative pain management
- novel local anesthetics
- cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques
- modalities (techniques, technologies, or drug regimen) to prolong the effect of local anesthetics
- ERAS-related studies
- AI applications in regional anesthesia and pain management
- innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield
- studies comparing new technologies/simulation (such as EpiFaith, SPRint PNS system, or CompuFlo) with traditional methods in improving regional anesthesia and pain management
- regenerative medicine
- nutritional pain medicine
- application of bone marrow aspirate concentration or other stem cell components in pain medicine
- multidisciplinary/comprehensive care program
- transarterial embolization for pain management
- joint denervation for pain management
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