Decoding Neurodegeneration: Insights From Multi-Omics and Neuroimaging Integration
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 11
Special Issue Editor
Special Issue Information
Dear Colleagues,
In this Special Issue, we aim to compile cutting‑edge research and comprehensive reviews that accomplish the following goals:
- Integrate multi‑omics datasets (genomic, transcriptomic, proteomic, metabolomic, and epigenomic) to identify novel biomarkers and therapeutic targets;
- Leverage systems biology and network analysis approaches to map molecular interactions driving neurodegeneration;
- Employ advanced neuroimaging and electrophysiological techniques—EEG, PET, fNIRS, fMRI, DTI, TMS, and ECG—in tandem with biomolecular biomarkers to link molecular signatures with functional and structural brain changes;
- Explore single‑cell and spatial omics methods to resolve cellular heterogeneity in affected brain regions;
- Highlight translational studies that bridge omics discoveries with in vivo models and clinical applications.
I look forward to collaborating with leading experts in the field, and to showcasing work that will deepen our mechanistic understanding and accelerate the development of diagnostic and therapeutic strategies for neurodegenerative diseases.
Dr. Abdulhakim Al-Ezzi
Guest Editor
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Keywords
- neurodegenerative
- neuroimaging
- executive functions
- electrophysiology
- brain connectivity
- multi omics data
- bio-molecular data
- biomarkers
- systems biology
- single-cell omics
- translational neuroscience
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