Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Heart Failure: From Biomarkers to Targeted Therapies
edited by
submission deadline 31 Dec 2025 | Viewed by 609 | Submission Open
Keywords: biomarkers in heart failure; GDMT in heart failure; targeted therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Navigating the Complex Landscape of Non-Communicable Respiratory Diseases: Emerging Challenges and Opportunities
edited by Katya Rigatto
submission deadline 31 Dec 2025 | Viewed by 506 | Submission Open
Keywords: non-communicable respiratory diseases; asthma; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews on Diabetes Pathophysiology and Treatment
edited by
submission deadline 31 Dec 2025 | Viewed by 477 | Submission Open
Keywords: type 1 diabetes mellitus; type 2 diabetes mellitus; pathophysiology; treatment; self-management; technology; continuous glucose monitoring; pump therapy; digital applications
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Respiratory Diseases
edited by
submission deadline 31 Dec 2025 | Viewed by 467 | Submission Open
Keywords: asthma; COPD; bronchiectasis; genetic; therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Liver Fibrosis: Molecular Mechanisms, Potential Therapeutic Targets and Clinical Biomarkers, 2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 417 | Submission Open
Keywords: liver fibrosis treatment; therapeutic target biomarker; hepatitis; NAFLD; NASH; MAFLD; HSC; GPCR; immunity cell death
(This special issue belongs to the Section Molecular and Translational Medicine)
CDK Inhibitors: A New Wave of Therapeutic Agents for Human Diseases
edited by Mengqian Chen
submission deadline 31 Dec 2025 | Viewed by 410 | Submission Open
Keywords: cyclin-dependent kinases (CDKs); cell-cycle CDKs; transcriptional CDKs; CDK inhibitors; CDK degraders; cancer therapeutics; inflammatory diseases; neurodegenerative disorders; pharmacology; clinical trials
(This special issue belongs to the Section Cancer Biology and Oncology)
Neglected Infectious Diseases: From Pathophysiology to Therapy
edited by Raimunda Nonata Ribeiro Sampaio
submission deadline 31 Dec 2025 | Viewed by 370 | Submission Open
Keywords: pathophysiology; host– parasite infection interactions; diagnostic tools; therapeutic intervention; novel biomarkers
(This special issue belongs to the Section Microbiology in Human Health and Disease)
State-of-the-Art Neurobiology and Clinical Neuroscience in the United States
edited by and
submission deadline 31 Dec 2025 | Viewed by 333 | Submission Open
Keywords: neurobiology; neuroscience; bioinformatics; Alzheimer’ s disease; Parkinson’ s disease; imaging; neurotransmitters; neurodegeneration; clinical; population genetics
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Nanomedicine Applications in the Diagnosis and Treatment of Neurodegenerative Diseases
edited by
submission deadline 31 Dec 2025 | Viewed by 323 | Submission Open
Keywords: neurodegenerative diseases; nanomedicine; blood– brain barrier permeability; early diagnosis and treatment; biosensing and bioimaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
State-of-the-Art Molecular and Translational Medicine in USA submission deadline 31 Dec 2025 | Viewed by 285 | Submission Open
Keywords: diagnostics; therapeutics; prevention; cellular biology; disease mechanisms; precision medicine; biomarker discovery; immunotherapies; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Neuromuscular Diseases: From Pathophysiology to Novel Therapeutic Approaches
edited by Marco A.F. Fernandes
submission deadline 31 Dec 2025 | Viewed by 282 | Submission Open
Keywords: neuromuscular diseases; amyotrophic lateral sclerosis (ALS); muscular dystrophy; myasthenia gravis; neuromyotonia; peripheral neuropathy; pathophysiology; gene therapy; targeted drugs; regenerative medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Challenges in the Study of Liver Diseases: From Molecular Pathogenesis to Therapeutic Approaches—4th Edition
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 264 | Submission Open
Keywords: liver diseases and related pathologies; non-alcoholic fatty liver diseases (NAFLDs); obesity; type 2 diabetes; cardiovascular diseases; gut– liver axis; viral hepatitis; alcoholic liver diseases (ALDs); cholestatic disorders; personalized medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Fetal Medicine: New Insights and Future Direction submission deadline 31 Dec 2025 | Viewed by 225 | Submission Open
Keywords: fetal medicine; fetal therapy; prenatal screening; congenital defects; high-risk pregnancy
(This special issue belongs to the Section Molecular and Translational Medicine)
Unleashing the Power of Innovative Nanoparticles for Enhanced Radiation Therapy
edited by Fangchao Jiang
submission deadline 31 Dec 2025 | Viewed by 210 | Submission Open
Keywords: nanomedicine; drug delivery; radiation therapy; nanotheranostics; nanoparticles; cancer treatment; biomaterial
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Supraventricular and Ventricular Cardiac Arrhythmias Systemic Implications: From Mechanisms to Clinical Treatment submission deadline 31 Dec 2025 | Viewed by 206 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; ventricular tachycardia; AVNRT; PVC; supraventricular tachycardia; catheter ablation; electrophysiological study; heart failure; arrhythmias diagnostic; antiarrhythmic treatment; biomarkers; ion channels; cardiac resynchronization therapy; ICD
(This special issue belongs to the Section Molecular and Translational Medicine)
Zebrafish Models for Development and Disease—5th Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 193 | Submission Open
Keywords: disease model; drug screening model; teratogen screening; toxicological screening; neuroscience; behavior; developmental biology
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Regulation of Cancer Progression and Metastasis to Identify Novel Treatment Strategies
edited by
submission deadline 31 Dec 2025 | Viewed by 178 | Submission Open
Keywords: cancer; cancer progression; cancer treatment; solid tumors; immune response; metastasis; tumor suppressor; oncogene
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Review: Advanced Manufacturing, Biomaterials, and Stem Cells for Tissue and Regenerative Engineering submission deadline 31 Dec 2025 | Viewed by 163 | Submission Open
Keywords: advanced manufacturing; biomaterials; tissue engineering; regenerative medicine
(This special issue belongs to the Section Biomedical Engineering and Materials)
NASH and Hepatocellular Carcinoma (HCC)—2nd Edition
edited by , and Xin Yang
submission deadline 31 Dec 2025 | Viewed by 136 | Submission Open
Keywords: NAFLD; NASH; HCC; obesity; inflammation; immunotherapy; stress
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Reviews in Imaging Technology for Human Diseases submission deadline 31 Dec 2025 | Viewed by 130 | Submission Open
Keywords: medical imaging; advanced radiological techniques; artificial intelligence; molecular imaging; computed tomography (CT); magnetic resonance imaging (MRI); ultrasound; fluoroscopy; optical imaging; liquid biopsy
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in Wound Healing
edited by and
submission deadline 31 Dec 2025 | Viewed by 128 | Submission Open
Keywords: wound healing; scar and keloid; diabetic ulcers; multi-omics analysis for wound healing; biomaterials for wound healing; tissue engineering for wound healing; wound infection management; clinical trials and cases of wound healing
(This special issue belongs to the Section Molecular and Translational Medicine)
Diagnosis, Pathogenesis and Treatment of CNS Tumors (2nd Edition)
edited by
submission deadline 31 Dec 2025 | Viewed by 119 | Submission Open
Keywords: CNS tumors; diagnosis; pathogenesis; treatment; prognosis; molecular markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanobiomaterials with Antimicrobial and Anticancer Applications: Second Edition
edited by and
submission deadline 31 Dec 2025 | Viewed by 114 | Submission Open
Keywords: nanobiomaterials; nanomaterials biomaterials; anti-bacterial; anti-cancer
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Advances in Hematological Malignancies: Diagnostic Strategies, Molecular Mechanisms, Prognostic Markers and Therapeutic Approaches
edited by José Antonio García-Vela and Fernando Martin-Moro
submission deadline 31 Dec 2025 | Viewed by 113 | Submission Open
Keywords: hematological malignancies; diagnostic strategies; hematopathology; flow cytometry; molecular biology; prognostic markers; targeted therapies; immunotherapy; cellular therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Current Perspectives on Gynecologic Cancers
edited by
submission deadline 31 Dec 2025 | Viewed by 95 | Submission Open
Keywords: gynecology; genetics; biology; bioinformatics; review; predictive model; artificial intelligence
(This special issue belongs to the Section Cancer Biology and Oncology)
Mitochondrial Function as a Target in Nanomedicine submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open
Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds.
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Omics Approaches on Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential Therapeutic Targets, 3rd Edition submission deadline 31 Dec 2025 | Viewed by 69 | Submission Open
Keywords: IMIDs; IBD; Crohn’ s disease; ulcerative colitis; SLE; Sjogren’ s syndrome; rheumatoid arthritis; psoriatic arthritis; multiple sclerosis; bulk and single-cell omics; multi-omics flow cytometry; next-generation microscopy; tissue microarrays; systems biology
(This special issue belongs to the Section Immunology and Immunotherapy)
Breast Cancer Research: Charting Future Directions submission deadline 31 Dec 2025 | Viewed by 63 | Submission Open
Keywords: personalized medicine; biomarkers for early detection; immunotherapy; patient-reported outcomes
(This special issue belongs to the Section Cancer Biology and Oncology)
New Insights in Reproductive Health and Disease
edited by
submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open
Keywords: reproductive health; artificial intelligence; fertility preservation; stem cells; gene therapy; materials; meiosis; DNA double-strand break; ovarian dysfunction; nanomedicine; pregnancy complications
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements and Innovations in Chemotherapy
edited by
submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open
Keywords: chemotherapy; drug resistance; immunotherapy; combination therapy; drug delivery systems; novel agents; personalized medicine; tumor microenvironment
(This special issue belongs to the Section Cell Biology and Pathology)
Exploring Neuroinflammation in Central and Peripheral Neuropathic Pain and Related Disorders
edited by
submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open
Keywords: neuroinflammation; neuropathic pain; central nervous system; peripheral nervous system; affective disorders; cognitive disorders; in silico modeling; in vitro assays; in vivo models; medical and non-pharmacological interventions
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Research on Diabetic Retinopathy
edited by Stamatios Lampsas
submission deadline 31 Dec 2025 | Viewed by 56 | Submission Open
Keywords: diebetic retinopathy; retinal diseases; novel treatment strategies; progression; pathogenetic mechanisms; non-proliferative diabetic retinopathy; proliferative diabetic retinopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
Three-Dimensional Printed Meshes in Guided Bone Regeneration submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open
Keywords: 3D– 4D printing; vascular metabolism; mucosal stiffness; bone and gingival cells metabolism; bioprinting; melt electrowriting; shape-memory materials; titanium and polycaprolactone meshes
(This special issue belongs to the Section Biomedical Engineering and Materials)
Mechanism of Mesenchymal Stromal Cells and Their Derivatives in Regenerative Medicine
edited by Jia Xian Law and
submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; stem cell; extracellular vesicle; mechanism of action; paracrine factor; secretome; tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders
edited by and Chiara Lucchi
submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open
Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
HIV Therapy: The Latest Developments in Antiviral Drugs submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open
Keywords: HIV; antiviral drugs; experimental therapeutics; drug discovery; viral reservoirs; mechanism of action; preclinical models; novel HIV targets; antiretroviral therapy (ART); immunotherapy (experimental aspects)
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Heart–Brain Axis
edited by Teresa Soda
submission deadline 31 Dec 2025 | Viewed by 49 | Submission Open
Keywords: heart– brain axis; neurocardiology; autonomic nervous system; neuroinflammation; cardiac– cerebral syndromes; psychocardiology; calcium signaling; synaptic plasticity; ion transport; translational neuroscience
(This special issue belongs to the Section Molecular and Translational Medicine)
Pharmacogenomics and Drug Metabolism: From Cytochrome P450 to Emerging Enzymatic Pathways submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open
Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; pharmacogenomics; biotransformation; orphan enzymes; redox biology; enzyme engineering; multi-omics approaches; personalized medicine
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
The Role of Telomere and Telomerase in Human Disease-2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open
Keywords: telomere; telomerase; cancer; aging
(This special issue belongs to the Section Molecular and Translational Medicine)
Dopamine and Androgen Receptor Signaling: Novel Insights in Cancer Biology
edited by Srijan Acharya
submission deadline 31 Dec 2025 | Viewed by 43 | Submission Open
Keywords: dopamine signaling; androgen receptor; cancer biology; hormone-sensitive tumors; signal transduction; tumor microenvironment; neurotransmitters in cancer; prostate cancer; breast cancer; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Biology of Cancer: From Biomarkers to Targeted Therapy
edited by
submission deadline 31 Dec 2025 | Viewed by 38 | Submission Open
Keywords: molecular biology; carcinogenesis; cancer; biomarkers; prognostic markers; predictive markers; precision medicine; targeted therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Oxidative Stress in Health and Disease
edited by Federica Mannino
submission deadline 31 Dec 2025 | Viewed by 34 | Submission Open
Keywords: oxidative stress; inflammation; human diseases; apoptosis; peroxidation; DNA damage; mitochondria
(This special issue belongs to the Section Cell Biology and Pathology)
Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 34 | Submission Open
Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therap; tumor growth; tumor invasion; angiogenesis; tumor metastasis; immune response modulation
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Chondrocyte Biology (2nd Edition)
edited by
submission deadline 31 Dec 2025 | Viewed by 32 | Submission Open
Keywords: osteoarthritis; chondrocyte; differentiation; proliferation; signaling pathways; transcription factor; inflammation; cellular processes; cartilage repair
(This special issue belongs to the Section Cell Biology and Pathology)
Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches—2nd Edition
edited by Vassilis Filiopoulos and
submission deadline 31 Dec 2025 | Viewed by 32 | Submission Open
Keywords: glomerular disease; glomerulonephritis; glomerulopathy; podocytopathies; ciliopathies; cystic kidney disease; polycystic kidney disease; tolvaptan; vasopressin
(This special issue belongs to the Section Molecular and Translational Medicine)
MicroRNAs in Precision Medicine: Regulation, Biomarkers and Novel Therapeutics
edited by Shing Cheng Tan
submission deadline 31 Dec 2025 | Viewed by 32 | Submission Open
Keywords: MicroRNAs; non-coding RNAs; biomarkers; therapeutic targets; cancer; omics technologies; precision medicine; disease pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Precision Oncology for Thyroid Carcinoma: Integrating Artificial Intelligence, Genomics and Molecular Diagnostics
edited by
submission deadline 31 Dec 2025 | Viewed by 30 | Submission Open
Keywords: thyroid carcinoma; artificial intelligence; genomics; precision oncology; molecular diagnostics
(This special issue belongs to the Section Cancer Biology and Oncology)
Epigenetics in Human Cancer: Emerging Biomarkers and Therapeutic Targets
edited by
submission deadline 31 Dec 2025 | Viewed by 30 | Submission Open
Keywords: cancer; epigenetics; DNA methylation; histone modification; chromatin remodeling; non-coding RNAs; therapeutic resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches—2nd Edition
edited by
submission deadline 31 Dec 2025 | Viewed by 29 | Submission Open
Keywords: gastrointestinal cancers; microbiota; anticancer therapy; immunotherapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Genetic Research on Colorectal Cancers
edited by
submission deadline 31 Dec 2025 | Viewed by 27 | Submission Open
Keywords: high microsatellite instability; epigenetic age acceleration; spatial omics and single-cell sequencing; cold tumors and immunotherapy; driver gene; DNA replication repair; liquid biopsy; ctDNA
(This special issue belongs to the Section Cancer Biology and Oncology)
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