Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Progress in Wound Healing
edited by
submission deadline 31 May 2026 | Viewed by 79 | Submission Open
Keywords: wound healing; tissue engineering; nanoparticle
(This special issue belongs to the Section Biomedical Engineering and Materials)
Innovative Drug Target Discovery in Cancer: From Molecular Mechanisms to Therapeutic Targets
edited by Rakesh Nair
submission deadline 31 May 2026 | Viewed by 79 | Submission Open
Keywords: cancer therapy; drug target; drug resistance; oncology drug development; cancer metastasis mechanisms; signaling pathways; biomarker
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Current Challenges and Future Perspectives of Antimicrobial Therapy submission deadline 31 May 2026 | Viewed by 74 | Submission Open
Keywords: antibiotics; antifungals; antimicrobial resistance; antimicrobial stewardship; drug safety and efficacy; resistance mechanisms
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bone, Tooth, and Periodontal Ligament Regeneration Biomaterial Advances
edited by and Marianne Sordi
submission deadline 31 May 2026 | Viewed by 64 | Submission Open
Keywords: bone regeneration; tooth regeneration; periodontal ligament; biomaterials; organoids; scaffolds; bioactive ceramics; polymers; composites; tissue engineering; stem cells; growth factors; clinical translation
(This special issue belongs to the Section Biomedical Engineering and Materials)
Crosstalk Between Cardiovascular Health and Cellular Metabolism
edited by and
submission deadline 31 May 2026 | Viewed by 55 | Submission Open
Keywords: cellular metabolism; oxidative stress; antioxidants; cardiovascular health; inflammation; metabolic disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Clinical Pathology in Cancer: From Diagnosis to Precision Medicine
edited by
submission deadline 31 May 2026 | Viewed by 54 | Submission Open
Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker
(This special issue belongs to the Section Cell Biology and Pathology)
Bioengineering and Translational Research for Bone and Joint Disorders
edited by Danilo Donati
submission deadline 31 May 2026 | Viewed by 47 | Submission Open
Keywords: musculoskeletal diseases; advanced materials; stem cell therapies; tissue engineering strategies
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advances in Atherosclerosis: From Pathogenesis to Diagnostics and Targeted Therapies
edited by and Ana Peterlin
submission deadline 31 May 2026 | Viewed by 44 | Submission Open
Keywords: atherosclerosis; molecular pathogenesis; diagnostic imaging modalities; biomarkers
(This special issue belongs to the Section Cell Biology and Pathology)
Neurodegenerative Diseases: Recent Advances and Future Perspectives, 2nd Edition submission deadline 25 Jun 2026 | 2 articles | Viewed by 5950 | Submission Open
Keywords: neurodegeneration; neuroprotection; dementia; Parkinson’ s disease
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanism in Inflammation and Immunity: 2nd Edition
edited by Anella Saviano
submission deadline 29 Jun 2026 | Viewed by 65 | Submission Open
Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity
(This special issue belongs to the Section Immunology and Immunotherapy)
Progress in Neurodevelopmental Disorders Research submission deadline 30 Jun 2026 | 6 articles | Viewed by 34455 | Submission Open
Keywords: neurodevelopmental disorders; autism spectrum disorder; attention deficit hyperactivity disorder
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Feature Reviews on Cardiovascular and Metabolic Diseases
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 19183 | Submission Open
Keywords: cardiovascular diseases; metabolic diseases; global health; disease prevention; innovative treatments
(This special issue belongs to the Section Cell Biology and Pathology)
Dualistic Equilibrium in Neurotransmission and Beyond: Unraveling the Pathophysiology and Unlocking Novel Therapeutic Targets in Neuropsychiatric Disorders—2nd Edition submission deadline 30 Jun 2026 | 2 articles | Viewed by 10753 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; cognitive dysfunction; multiple sclerosis; stroke; migraine; chronic pain; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; brain injuries; comorbidity; brain plasticity; transcranial magnetic stimulation (TMS); transcranial direct current stimulation (tDCS)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Insights in Hematologic Malignancies: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by
submission deadline 30 Jun 2026 | 6 articles | Viewed by 8342 | Submission Open
Keywords: leukemia; hematological malignancies; tumor microenvironment; disease models; precision medicine; immunotherapy; targeted therapy; drug resistance; biomarkers; translational research
(This special issue belongs to the Section Cancer Biology and Oncology)
Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition submission deadline 30 Jun 2026 | 6 articles | Viewed by 7744 | Submission Open
Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Brain Tumor Diagnosis: Innovations and Emerging Technologies submission deadline 30 Jun 2026 | 4 articles | Viewed by 7221 | Submission Open
Keywords: brain tumor diagnosis; artificial intelligence in oncology; deep learning in medical imaging; machine learning models; predictive analytics in healthcare; digital pathology; glioma detection; multi-modal data integration; neuro-oncology; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Novel Drug Discovery, Synthesis, and Evaluation
edited by
submission deadline 30 Jun 2026 | 3 articles | Viewed by 6876 | Submission Open
Keywords: drug synthesis; novel therapies; disease targets; medicinal chemistry; computational methods; screening techniques; pharmaceutical development; target identification
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Genomics and Bioinformatics of Human Disease submission deadline 30 Jun 2026 | 3 articles | Viewed by 6625 | Submission Open
Keywords: genomics; bioinformatics; precision medicine; single-cell RNA sequencing; genetic variations; cellular heterogeneity; AI/ML; pathogenicity prediction
(This special issue belongs to the Section Molecular and Translational Medicine)
Sphingolipid Metabolism and Signaling in Health and Diseases: 2nd Edition submission deadline 30 Jun 2026 | 3 articles | Viewed by 5395 | Submission Open
Keywords: sphingolipids; glycosphingolipids; gangliosides; sphingosine-1-phosphate; cell homeostasis; neurodegeneration; neurodevelopment; inflammation; diabetes; cystic fibrosis; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Prostate Cancer Targeted Therapy: Highlighting Advances in Precision Medicine and Rational Combination Approaches
edited by Alan P. Lombard
submission deadline 30 Jun 2026 | 3 articles | Viewed by 4656 | Submission Open
Keywords: prostate cancer; precision medicine; targeted therapeutics; rational drug combinations; clinical biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Pancreatic, Liver, Biliary Tract and Intestinal Diseases: Pathogenesis, Diagnostics and Therapy—2nd Edition submission deadline 30 Jun 2026 | 3 articles | Viewed by 4547 | Submission Open
Keywords: inflammatory bowel disease; gastrointestinal tumor; gastrointestinal cancer; acute pancreatitis; chronic pancreatitis; pancreatic cyst; biliary cyst; liver disease; biliary tract disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Coronary Artery Disease: From Pathophysiology to Therapeutic Strategies submission deadline 30 Jun 2026 | 2 articles | Viewed by 4473 | Submission Open
Keywords: pathophysiological concept of coronary artery disease; coronary microvascular dysfunction; chronic coronary syndrome; acute coronary syndrome; post-acute coronary syndrome with heart failure; diagnostics in coronary artery disease; therapeutic strategies in CAD; revascularization
(This special issue belongs to the Section Cell Biology and Pathology)
New Insights in Radiotherapy: Bridging Radiobiology and Oncology
edited by and I-Tsang Chiang
submission deadline 30 Jun 2026 | 4 articles | Viewed by 4295 | Submission Open
Keywords: tissue-sparing effect; bystander effect; factors that affect radiation-induced lethality; radiation-induced abscopal effect; mechanisms that enhance tissue radiosensitivity; synergistic effect from radiotherapy and immunotherapy; regulatory perspectives on medical radiation safety
(This special issue belongs to the Section Cancer Biology and Oncology)
Two Decades of Advances in Colorectal Cancer Prevention and Treatment: From Aspirin to Precision Oncology
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3952 | Submission Open
Keywords: immunotherapy; biomarkers; colorectal cancer; targeted therapies; molecular pathways
(This special issue belongs to the Section Cancer Biology and Oncology)
Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches (4th Edition)
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3914 | Submission Open
Keywords: oxidative stress; inflammation; molecular mechanisms; pharmacotherapy; longevity; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
Diagnostic and Therapeutic Challenges of CAR-T Cell Therapy
edited by Vincenzo Maria Perriello
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3554 | Submission Open
Keywords: CAR-T therapy; immunotherapy; relapsed/refractory diffuse large B cell lymphoma (r/r DLBCL); relapsed/refractory mantle cell lymphoma (r/r MCL); B-acute lymphoblastic leukemia (r/r B-ALL); bridging therapy; cytokine release syndrome (CRS); immune effector cell associated neurotoxicity (ICANS); biomarkers; PET/CT assessment after CAR-T cell therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Advances in Type 2 Diabetes: Insulin Regulation and Therapeutic Strategies
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3134 | Submission Open
Keywords: type 2 diabetes; insulin regulation; glycemic control; insulin resistance; therapeutic strategies; personalized medicine; GLP-1 receptor agonists; SGLT2 inhibitors; novel insulin formulations; non-insulin therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition submission deadline 30 Jun 2026 | 2 articles | Viewed by 2757 | Submission Open
Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Therapeutic Strategies for Epilepsy: Bridging Research and Clinical Practice
edited by Tanveer Singh
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2233 | Submission Open
Keywords: epilepsy; status epilepticus; MRI; EEG; inhibitory neurotransmission; immunohistochemistry; gene regulation; neurodegeneration; precision medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Glioma Therapy: Current Status and Future Prospects
edited by Bernd Kaina
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2043 | Submission Open
Keywords: glioblastoma; temozolomide; nitrosoureas; immunotherapy; biologicals; tyrosine kinase inhibitors; senotherapeutics
(This special issue belongs to the Section Cancer Biology and Oncology)
An Update on Mechanisms and Treatments for Thyroid Cancer in Current Oncology, 2nd Edition
edited by Zhilong Ai
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1731 | Submission Open
Keywords: thyroid cancer; mechanisms; treatments; biomarkers; precision medicine; infiltration; metastasis
(This special issue belongs to the Section Cancer Biology and Oncology)
Epilepsy: Pathomechanism, Diagnostics, and Novel Treatment Options submission deadline 30 Jun 2026 | 1 articles | Viewed by 1640 | Submission Open
Keywords: epilepsy; pathophysiology; neurobiology; molecular pathways; experimental models of epilepsy; neuroinflammation; seizure prediction; biomarker discovery; electrophysiological studies; precision neurology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Updates on Kawasaki Disease
edited by Eisuke Suganuma
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1600 | Submission Open
Keywords: coronary artery aneurysm; cluster; individualized treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Cardiovascular Diseases, 2nd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 1593 | Submission Open
Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies
(This special issue belongs to the Section Molecular and Translational Medicine)
Small Intestinal Bacterial Overgrowth and Antimicrobial submission deadline 30 Jun 2026 | 1 articles | Viewed by 1417 | Submission Open
Keywords: small intestine bacterial overgrowth; antibiotics; probiotics; gut microbiome
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in the Pathogenesis and Treatment of Acute Myeloid Leukemia—2nd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 1351 | Submission Open
Keywords: acute myeloid leukemia; target therapies; molecular pathogenesis; biological therapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Coronary Artery Disease: Current Evidence and Future Perspectives
edited by Tadateru Takayama
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1302 | Submission Open
Keywords: coronary artery disease; lipid-lowering therapy; residual risk; small dense LDL; lipoprotein(a); endothelial dysfunction; oxidative stress; inflammation; biomarkers; cardiovascular prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Precision Oncology for Thyroid Carcinoma: Integrating Artificial Intelligence, Genomics and Molecular Diagnostics
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1291 | Submission Open
Keywords: thyroid carcinoma; artificial intelligence; genomics; precision oncology; molecular diagnostics
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular and Histopathological Background of Diabetic Neuropathy
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1222 | Submission Open
Keywords: diabetic neuropathy; insulin; hyperglycaemia; peripheral neuropathy; autonomic neuropathy; proximal neuropathy; enteric neuropathy; mononeuropathy
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Neurophysiology and the Treatment of Parkinson’s Disease
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 889 | Submission Open
Keywords: movement disorders; hypokinetic movement disorders; Parkinson’ s disease; levodopa; treatment; neurophysiology; neuroplasticity; motor learning
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Therapeutic Resistance in Oral Cancer: Mechanisms, Biomarkers, and Novel Strategies to Restore Treatment Responses submission deadline 30 Jun 2026 | 1 articles | Viewed by 840 | Submission Open
Keywords: oral cancer; OSCC; chemotherapy; radiotherapy; immunotherapy; therapeutic resistance; HNSCC; biomarker; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathogenesis and Novel Diagnostic Techniques in Juvenile Idiopathic Arthritis—Second Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 755 | Submission Open
Keywords: juvenile idiopathic arthritis; pathogenesis; cartilage and bone anabolism and catabolism; diagnostics; treatment; prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Immunology and Immunotherapy in Europe (2nd Edition)
edited by
submission deadline 30 Jun 2026 | Viewed by 684 | Submission Open
Keywords: immunology; immunotherapy; lymphocytes; macrophages; eosinophils; neutrophils; diseases
(This special issue belongs to the Section Immunology and Immunotherapy)
Urogenital Cancers: New Molecular and Translational Aspects on Carcinogenesis and Treatments (2nd Edition) submission deadline 30 Jun 2026 | 1 articles | Viewed by 678 | Submission Open
Keywords: prostate cancer; bladder cancer; renal cell carcinoma; testicular cancer; ovarian cancer; endometrial cancer; carcinogenesis; biomarkers; early diagnosis; upper urinary tract tumors; diagnosis; treatment; environmental factors; diet
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (3rd Edition)
edited by Sung Il Im
submission deadline 30 Jun 2026 | 1 articles | Viewed by 642 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in 3D Bioprinting: From Materials to Functional Tissue Constructs
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 642 | Submission Open
Keywords: 3D bioprinting; tissue engineering; biofabrication; regenerative medicine; bioprinted skin; organ-on-a-chip; biomaterials; vascularized constructs
(This special issue belongs to the Section Biomedical Engineering and Materials)
Breast Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatments
edited by Ioanna Akrida
submission deadline 30 Jun 2026 | 1 articles | Viewed by 515 | Submission Open
Keywords: breast cancer carcinogenesis; triple-negative breast cancer (TNBC); HER2; endocrine therapy; neoadjuvant chemotherapy (NACT); immunotherapy; tumor profiling molecular tests; liquid biopsy circulating tumor cells (CTCs); circulating tumor DNA (ctDNA)
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions submission deadline 30 Jun 2026 | Viewed by 502 | Submission Open
Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetic Research of Hearing Loss
edited by Ling Lu, Jun Yang, and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 497 | Submission Open
Keywords: genetic; sensorineural hearing loss; inner ear drug delivery; gene therapy; genetic screening; hearing aids; cochlear implantation
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Current Status and Future Directions of Molecular Genetics and Genetic Diseases
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 452 | Submission Open
Keywords: molecular genetics; genetic diseases; genetic therapy
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
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